Citation Impact
Citing Papers
Anti-Markovnikov alkene oxidation by metal-oxo–mediated enzyme catalysis
2017 StandoutScienceNobel
Olefin Cyclopropanation via Carbene Transfer Catalyzed by Engineered Cytochrome P450 Enzymes
2012 StandoutScienceNobel
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
A Small-Molecule Modulator of Poly-α2,8-Sialic Acid Expression on Cultured Neurons and Tumor Cells
2001 StandoutScienceNobel
Isothermal amplified detection of DNA and RNA
2014
Expansive discovery of chemically diverse structured macrocyclic oligoamides
2024 StandoutScienceNobel
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
Single-crystal x-ray diffraction structures of covalent organic frameworks
2018 StandoutScienceNobel
Ring-closing metathesis strategy to unsaturated γ- and δ-lactones: Synthesis of hydroxyethylene isostere for protease inhibitors
1998
Fluorination reactions in microreactors
2008
Tumor-targeting peptides from combinatorial libraries
2016
Dynamic combinatorial chemistry
2002
Macrocyclization by Ring‐Closing Metathesis in the Total Synthesis of Natural Products: Reaction Conditions and Limitations
2006
Emerging tools for bioluminescence imaging
2021
Dynamic Combinatorial Carbohydrate Libraries: Probing the Binding Site of the Concanavalin A Lectin
2004 Nobel
Modular click chemistry libraries for functional screens using a diazotizing reagent
2019 StandoutNatureNobel
Dynamic Covalent Chemistry
2002 StandoutNobel
Combinatorial and computational challenges for biocatalyst design
2001 StandoutNatureNobel
In vivo catalyzed new-to-nature reactions
2018
Total Synthesis of Complestatin (Chloropeptin II)
2010
Expanding diversity in dynamic combinatorial libraries: simultaneous exchange of disulfide and thioester linkages
2005
Synthetic metabolism: metabolic engineering meets enzyme design
2017
The remarkable metal-catalysed olefin metathesis reaction
2007 StandoutNature
In situ assembly of enzyme inhibitors using extended tethering
2003
Protonic and Temperature Modulation of Constituent Expression by Component Selection in a Dynamic Combinatorial Library of Imines
2006
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
Dynamic Covalent Chemistry on Self‐Templating Peptides: Formation of a Disulfide‐linked β‐Hairpin Mimic
2003
The influence of natural products upon drug discovery (Antiquity to late 1999)
2000
De novo design of luciferases using deep learning
2023 StandoutNatureNobel
Acyclic amino acid-catalyzed direct asymmetric aldol reactions: alanine, the simplest stereoselective organocatalyst
2005
Seeing (and Using) the Light: Recent Developments in Bioluminescence Technology
2020
Catalytic C–H functionalization by metal carbenoid and nitrenoid insertion
2008 StandoutNature
Genetically programmed chiral organoborane synthesis
2017 StandoutNatureNobel
Drug discovery by dynamic combinatorial libraries
2002 Nobel
Direct Asymmetric Intermolecular Aldol Reactions Catalyzed by Amino Acids and Small Peptides
2006
Atropisomerism, Biphenyls, and Fluorine: A Comparison of Rotational Barriers and Twist Angles
2004
Receptor‐Assisted Combinatorial Chemistry: Thermodynamics and Kinetics in Drug Discovery
2004
Atroposelective Synthesis of Axially Chiral Biaryl Compounds
2005 Standout
Staudinger Ligation: A New Immobilization Strategy for the Preparation of Small‐Molecule Arrays
2003
A Stepwise Huisgen Cycloaddition Process: Copper(I)-Catalyzed Regioselective “Ligation” of Azides and Terminal Alkynes
2002 StandoutNobel
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
Fragment-based drug discovery of carbonic anhydrase II inhibitors by dynamic combinatorial chemistry utilizing alkene cross metathesis
2006
Pseudodynamic Combinatorial Libraries: A Receptor‐Assisted Approach for Drug Discovery
2004
Towards the Optimal Screening Collection: A Synthesis Strategy
2007
Electrophilic Cyclization of 1,5‐Enynes
2010
Utilization of Self‐Sorting Processes To Generate Dynamic Combinatorial Libraries with New Network Topologies
2005
The exploration of macrocycles for drug discovery — an underexploited structural class
2008
A Bioorthogonal Reaction of N‐Oxide and Boron Reagents
2015 StandoutNobel
Catalyst‐Controlled Stereoselective Combinatorial Synthesis
2003
Effects of Tryprostatin Derivatives on Microtubule Assembly In Vitro and In Situ.
1998
The Second Total Synthesis of Diazonamide A
2003
Diarylprolinol Ethers: Expanding the Potential of Enamine/Iminium‐Ion Catalysis
2006
Metathesis Reactions in Total Synthesis
2005
Synthesis and biological evaluation of aryl azide derivatives of combretastatin a-4 as molecular probes for tubulin
2000
Nanoparticles, Proteins, and Nucleic Acids: Biotechnology Meets Materials Science
2001 Standout
Inhibitors of HIV‐1 Protease by Using In Situ Click Chemistry
2006 StandoutNobel
Click Chemistry In Situ: Acetylcholinesterase as a Reaction Vessel for the Selective Assembly of a Femtomolar Inhibitor from an Array of Building Blocks
2002 StandoutNobel
Chemical Strategies for Activity‐Based Proteomics
2003
Outrunning the Bear
2004
Recent Developments in Olefin Cross‐Metathesis
2003
Organic Azides: An Exploding Diversity of a Unique Class of Compounds
2005 Standout
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
2016 StandoutNatureNobel
In Situ Click Chemistry: Enzyme‐Generated Inhibitors of Carbonic Anhydrase II
2004 StandoutNobel
Convenient synthesis of novel macrocyclic urethanes: alkoxycarbonylation of amines and ring-closing metathesis strategy
1998
Synthesis of Diastereomers of Complestatin and Chloropeptin I: Substrate‐Dependent Atropstereoselectivity of the Intramolecular Suzuki–Miyaura Reaction
2008
Vancomycin Assembly: Nature's Way
2003
Atroposelective Synthesis of Axially Chiral Biaryl Compounds
2005
Atroposelective Total Synthesis of Axially Chiral Biaryl Natural Products
2010 Standout
Die Olefinmetathese in der organischen Synthese
1997
A Reversible, Unidirectional Molecular Rotary Motor Driven by Chemical Energy
2005 StandoutScienceNobel
Synthesis and Biological Evaluation of a Focused Mixture Library of Analogues of the Antimitotic Marine Natural Product Curacin A
2000
Mechanism-Based Profiling of Enzyme Families
2006
Improved synthesis of the northern hemisphere of epothilone A by a Sharpless asymmetric dihydroxylation
1999
Recent advances in olefin metathesis and its application in organic synthesis
1998 StandoutNobel
Monofluorination of Organic Compounds: 10 Years of Innovation
2015 Standout
Natural Product-like Combinatorial Libraries Based on Privileged Structures. 1. General Principles and Solid-Phase Synthesis of Benzopyrans
2000
Total Synthesis of the Teicoplanin Aglycon
2000
Copper-Mediated Coupling Reactions and Their Applications in Natural Products and Designed Biomolecules Synthesis
2008 Standout
Harnessing the Biosynthetic Code: Combinations, Permutations, and Mutations
1998 Science
Atropodiastereoselective Cleavage of Configurationally Unstable Biaryl Lactones with Amino Acid Esters
2006
Photoremovable Protecting Groups in Chemistry and Biology: Reaction Mechanisms and Efficacy
2012 Standout
Chemical Genetics
2006
Fehlschläge und Umwege bei Totalsynthesen in den neunziger Jahren
2000
Olefinmetathese und mehr
2000
Staudinger‐Ligation: eine Immobilisierungsstrategie zur Herstellung von Wirkstoff‐Arrays
2003
Olefin Metathesis in Organic Chemistry
1997
Natural Product Synthesis Using Multicomponent Reaction Strategies
2009 Standout
Methodologies for Generating Solution-Phase Combinatorial Libraries
2000
The Olefin Metathesis Approach to Epothilone A and Its Analogues
1997
Chemical biology of dynamic combinatorial libraries
2002
Proline-catalysed asymmetric aldol reaction in the room temperature ionic liquid [bmim]PF6
2002
The lactone concept—a novel approach to the metal-assisted atroposelective construction of axially chiral biaryl systems
2002
Total Syntheses of Epothilones A and B
1997
Cyclisation/cleavage of macrocycles by ring-closing metathesis on solid support—conformational studies
1997
Atropisomerism, biphenyls and the Suzuki coupling: peptide antibiotics
2001
Chemical Glycobiology
2001 StandoutScienceNobel
Bis Ring Closing Olefin Metathesis for the Synthesis of Unsaturated Polycyclic Ethers. O-Membered Ring Cyclization in Favor of C-Membered Ring Cyclization
1999
Benzotriazol-1-yl-sulfonyl Azide for Diazotransfer and Preparation of Azidoacylbenzotriazoles
2010
The atom, the molecule, and the covalent organic framework
2017 StandoutScienceNobel
Development and Applications of Bioluminescent and Chemiluminescent Reporters and Biosensors
2019
Solid-Phase Oligosaccharide Synthesis: Preparation of Complex Structures Using a Novel Linker and Different Glycosylating Agents
1999
Solid phase heterocyclic synthesis via ring closing metathesis: Traceless linking and cyclative cleavage through a carbon-carbon double bond
1997
Chiroptical Molecular Switches
2000 StandoutNobel
Synthese von mittleren Ringen durch Ringschluss-Metathese-Reaktion
2000
Ready Transformation of Partially Unprotected Thioglycosides into Glycosyl Fluorides Mediated by NIS/HF–Pyridine or Et3N·3HF
2008
Induction of a Preferred Sense of Twist in Flexible Diphenyls by Carbohydrate Scaffolds. Synthesis of Two “Naked” Ellagitannin Analogous
2001
In Situ Click Chemistry: Enzyme‐Generated Inhibitors of Carbonic Anhydrase II
2004 StandoutNobel
Extended Alkenyl Glycosides by Ruthenium-Catalyzed Cross-Metathesis Reaction and Application toward Novel C-Linked Pseudodisaccharides
1999
Der Aufbau von Vancomycin: so macht es die Natur
2003
Dynamic Combinatorial Chemistry
2006 Standout
Synthetic Methods for Fluorinated Olefins
2011
Alternative synthesis and thermal atropisomerism of a fully functionalized DEFG ring system of teicoplanin
2001
An "Endless" Route to Cyclic Polymers
2002 StandoutScienceNobel
Ring closing metathesis in organic synthesis: Evolution of a high speed, solid phase method for the preparation of β-turn mimetics
1999
Glycosyl fluorides from n-pentenyl-related glycosyl donors — Application to glycosylation strategies
2013
The development of anticancer ruthenium(ii ) complexes: from single molecule compounds to nanomaterials
2017 Standout
Olefin Metathesis and Beyond
2000 Standout
Makrolidanaloga des neuartigen Immunsuppressivums Sanglifehrin: eine neue Anwendung der Ringschluß-Metathese
1999
Aryl−Aryl Bond Formation by Transition-Metal-Catalyzed Direct Arylation
2007 Standout
Recent progress in the design and synthesis of artificial enzymes
2001
First and Second Generation Total Synthesis of the Teicoplanin Aglycon
2001
Tumor Selectivity of Hsp90 Inhibitors: The Explanation Remains Elusive
2006
Enzymatic Chemistry of Cyclopropane, Epoxide, and Aziridine Biosynthesis
2011
The Chemistry of Amine−Azide Interconversion: Catalytic Diazotransfer and Regioselective Azide Reduction
2002
Enzymatic construction of highly strained carbocycles
2018 StandoutScienceNobel
Supported Ionic Liquids. New Recyclable Materials for the L ‐Proline‐Catalyzed Aldol Reaction
2006
Diversifying Vancomycin via Chemoenzymatic Strategies
2005
Designing 129Xe NMR Biosensors for Matrix Metalloproteinase Detection
2006
Dynamic Combinatorial Chemistry
2001 ScienceNobel
The Asymmetric Suzuki Coupling Route to Axially Chiral Biaryls
2005
Click Chemistry In Situ: Acetylcholinesterase as a Reaction Vessel for the Selective Assembly of a Femtomolar Inhibitor from an Array of Building Blocks
2002 StandoutNobel
A Field Guide to Foldamers
2001 Standout
Applications of bioluminescence in biotechnology and beyond
2021
The total synthesis of vitamin B12
1973
Dynamic combinatorial chemistry
2002
Solid-phase organic reactions II: A review of the literature Nov 95–Nov 96
1997
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
Synthesis Mediated by Ring-Closing Metathesis – Applications in the Synthesis of Azasugars and Alkaloids
1999
Synthesis of Trisubstituted Alkenes via Olefin Cross-Metathesis
1999 StandoutNobel
DAST-Mediated Regioselective Anomeric Group Migration in Saccharides
2009
Reversible Optical Transcription of Supramolecular Chirality into Molecular Chirality
2004 StandoutScienceNobel
Molecular Borromean Rings
2004 StandoutScienceNobel
Combinatorial chemistry. Use of an intramolecular ruthenium catalyzed olefin/alkyne metathesis reaction in tandem with a Diels-Alder cycloaddition reaction to construct functionalized hexahydroisoindoles
1998
Metathesis Reactions of Pyrazolotriazinones Generate Dynamic Combinatorial Libraries
2005
Thermal Atropisomerism of Teicoplanin Aglycon Derivatives: Preparation of the P,P,P and M,P,P Atropisomers of the Teicoplanin Aglycon via Selective Equilibration of the DE Ring System
2000
l-Proline catalysed asymmetric aldol reactions in PEG-400 as recyclable medium and transfer aldol reactions
2005
Diastereodivergent Hydroxyfluorination of Cyclic and Acyclic Allylic Amines: Synthesis of 4-Deoxy-4-fluorophytosphingosines
2012
Design and synthesis of constrained epothilone analogs: The efficient synthesis of eleven-membered rings by olefin metathesis
1999
The ‘lactone method’: enantioselective preparation of novel P,N-biaryl ligands and their use in the synthesis of the biarylic alkaloids, ancistrotanzanine B and ancistroealaine A
2004
Impact of Natural Products on Developing New Anti-Cancer Agents
2009 Standout
Solid-phase organic reactions: A review of the recent literature
1996
Polyketide and Nonribosomal Peptide Antibiotics: Modularity and Versatility
2004 Science
A molecular meccano kit †
2000 StandoutNobel
Natural Product-Derived Modulators of Cell Cycle Progression and Viral Entry by Enantioselective Oxa Diels-Alder Reactions on the Solid Phase
2007
Ring-Closing Metathesis on Solid Support: Elaboration of a Cyclization/Cleavage Strategy Towards Unsaturated α-Ester-Substituted N-Heterocycles
1998
Ring-Opening Hydrofluorination of 2,3- and 3,4-Epoxy Amines by HBF4·OEt2: Application to the Asymmetric Synthesis of (S,S)-3-Deoxy-3-fluorosafingol
2011
The Size-Selective Synthesis of Folded Oligomers by Dynamic Templation
2002
The Development of L2X2RuCHR Olefin Metathesis Catalysts: An Organometallic Success Story
2000 StandoutNobel
Desoxyepothilone B: An efficacious microtubule-targeted antitumor agent with a promising in vivo profile relative to epothilone B
1998
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Dynamic Deconvolution of a Pre-Equilibrated Dynamic Combinatorial Library of Acetylcholinesterase Inhibitors
2001 Nobel
Asymmetric Enamine Catalysis
2007 StandoutNobel
Synthesis of the northern hemisphere of epothiline a by a ten-membered ring closing metathesis reaction
1999
Macrocycles by ring-closing-metathesis, XI: Syntheses of (R)-(+)-lasiodiplodin, zeranol and truncated salicylihalamides
1999
Design of higher valency in covalent organic frameworks
2020 StandoutScienceNobel
A facile and convenient synthesis of disarmed glycosyl fluorides using in situ-generated iodine monofluoride (see Ref. 1)
2012
Total Synthesis of the Vancomycin Aglycon
1999
Applications of Zr-Catalyzed Carbomagnesation and Mo-Catalyzed Macrocyclic Ring Closing Metathesis in Asymmetric Synthesis. Enantioselective Total Synthesis of Sch 38516 (Fluvirucin B1)
1997
Works of Nicolas Winssinger being referenced
Luciferase‐Induced Photouncaging: Bioluminolysis
2019
Luciferase-induced photoreductive uncaging of small-molecule effectors
2018
Applications of laser-polarized 129xe to biomolecular assays
2003
Synthesis of epothilones A and B in solid and solution phase
1997 Nature
Fluorescence-based detection of single nucleotide permutation in DNA via catalytically templated reaction
2007
PNA-encoded chemical libraries
2015
PNA-Encoded Protease Substrate Microarrays
2004
Synthesis and Biological Evaluation of Vancomycin Dimers with Potent Activity against Vancomycin-Resistant Bacteria: Target-Accelerated Combinatorial Synthesis
2001
From Split-Pool Libraries to Spatially Addressable Microarrays and Its Application to Functional Proteomic Profiling
2001
Solid-Phase Synthesis of Oligosaccharides: Construction of a Dodecasaccharide
1998
Activity Profile of Dust Mite Allergen Extract Using Substrate Libraries and Functional Proteomic Microarrays
2004
Modular Asymmetric Synthesis of Pochonin C
2004
DNA-templated release of functional molecules with an azide-reduction-triggered immolative linker
2011
Target-Accelerated Combinatorial Synthesis and Discovery of Highly Potent Antibiotics Effective Against Vancomycin-Resistant Bacteria
2000
Multiple simultaneous synthesis of phenolic libraries
1995
Molecular Editing of Kinase‐Targeting Resorcylic Acid Lactones (RAL): Fluoroenone RAL
2010
Totalsynthese von Vancomycin
1999
Festphasensynthese von Makrocyclen mit der Strategie der Abspaltung unter Cyclisierung: Anwendung der Stille-Kupplung bei der Synthese von (S)-Zearalenon
1998
A General and Highly Efficient Solid Phase Synthesis of Oligosaccharides. Total Synthesis of a Heptasaccharide Phytoalexin Elicitor (HPE)
1997
The Art and Science of Total Synthesis at the Dawn of the Twenty-First Century
2000
Target-Accelerated Combinatorial Synthesis and Discovery of Highly Potent Antibiotics Effective Against Vancomycin-Resistant Bacteria
2000
Development of a Functionalized Xenon Biosensor
2004
Von Split-Pool-Molekülbibliotheken zu räumlich adressierbaren Mikro-Arrays und deren Einsatz in der funktionellen Proteomik
2001
Nucleic Acid-Templated Energy Transfer Leading to a Photorelease Reaction and its Application to a System Displaying a Nonlinear Response
2011
Solid Phase Synthesis of Macrocycles by an Intramolecular Ketophosphonate Reaction. Synthesis of a (dl)-Muscone Library
1998
IPy2BF4‐Mediated Glycosylation and Glycosyl Fluoride Formation
2007
Smartphone DNA or RNA Sensing Using Semisynthetic Luciferase-Based Logic Device
2020
The Art and Science of Total Synthesis at the Dawn of the Twenty-First Century
2000
Modular Asymmetric Synthesis of Pochonin C
2004
A New Photolabile Linker for the Photoactivation of Carboxyl Groups
2001
New Selenium-Based Safety-Catch Linkers: Solid-Phase Semisynthesis of Vancomycin
2000
Critical Analysis of Rate Constants and Turnover Frequency in Nucleic Acid-Templated Reactions: Reaching Terminal Velocity
2017
Chemie, Biologie und medizinische Anwendungen der Glycopeptid-Antibiotika
1999
Solid- and Solution-Phase Synthesis of Vancomycin and Vancomycin Analogues with Activity against Vancomycin-Resistant Bacteria
2001
Nucleic Acid Templated Chemical Reaction in a Live Vertebrate
2016
Photoreductive Uncaging of Fluorophore in Response to Protein Oligomers by Templated Reaction in Vitro and in Cellulo
2012
Solid and Solution Phase Synthesis and Biological Evaluation of Combinatorial Sarcodictyin Libraries
1998
Azidopeptide Nucleic Acid. An Alternative Strategy for Solid-Phase Peptide Nucleic Acid (PNA) Synthesis
2003
Der Stand der Totalsynthese zu Beginn des 21. Jahrhunderts
2000
Gezielt entworfene Epothilone: kombinatorische Synthese, Induktion der Tubulin‐Polymerisation und cytotoxische Wirkung gegen taxolresistente Tumorzellen
1997
Total Synthesis of Vancomycin—Part 4: Attachment of the Sugar Moieties and Completion of the Synthesis
1999
Profiling protein function with small molecule microarrays
2002
Synthesis of a PNA-encoded cysteine protease inhibitor library
2004
Imaging of mRNA in Live Cells Using Nucleic Acid-Templated Reduction of Azidorhodamine Probes
2009
Nucleic Acid Templated Uncaging of Fluorophores Using Ru-Catalyzed Photoreduction with Visible Light
2011
Design, Synthesis, and Biological Evaluation of HSP90 Inhibitors Based on Conformational Analysis of Radicicol and Its Analogues
2005
Total Synthesis of Vancomycin
1999
Chemistry, Biology, and Medicine of the Glycopeptide Antibiotics
1999
In cellulo protein labelling with Ru-conjugate for luminescence imaging and bioorthogonal photocatalysis
2015
Designed Epothilones: Combinatorial Synthesis, Tubulin Assembly Properties, abd Cytotoxic Action against Taxol‐Resistant Tumor Cells
1997