Citation Impact
Citing Papers
A Novel Germline Variant in CSF3R Reduces N-Glycosylation and Exerts Potent Oncogenic Effects in Leukemia
2018 StandoutNobel
Trained immunity: A program of innate immune memory in health and disease
2016 StandoutScience
High Frequency of Mutations of the PIK3CA Gene in Human Cancers
2004 StandoutScience
( R )-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible
2013 StandoutScienceNobel
Prospective isolation and molecular characterization of hematopoietic stem cells with durable self-renewal potential
2009
Inositol phosphatase SHIP1 is a primary target of miR-155
2009 Nobel
The Wnt/β-Catenin Pathway Is Required for the Development of Leukemia Stem Cells in AML
2010 Science
TOR Signaling in Growth and Metabolism
2006 Standout
Hif-2α is not essential for cell-autonomous hematopoietic stem cell maintenance
2013 StandoutNobel
Meis1 regulates the metabolic phenotype and oxidant defense of hematopoietic stem cells
2012
Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger
2009 Nature
Wnt Signaling and a Hox Protein Cooperatively Regulate PSA-3/Meis to Determine Daughter Cell Fate after Asymmetric Cell Division in C. elegans
2006
Mechanisms of type-I- and type-II-interferon-mediated signalling
2005 Standout
JAK Inhibition with Ruxolitinib versus Best Available Therapy for Myelofibrosis
2012 Standout
Quantitative production of macrophages or neutrophils ex vivo using conditional Hoxb8
2006
mTOR Interacts with Raptor to Form a Nutrient-Sensitive Complex that Signals to the Cell Growth Machinery
2002 Standout
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
2007 StandoutNobel
Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche
2011 StandoutNobel
The phosphatidylinositol 3-Kinase–AKT pathway in human cancer
2002 Standout
Cancer Epigenetics: From Mechanism to Therapy
2012 Standout
A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells
2006 Standout
In vitro and in vivo expansion of hematopoietic stem cells
2004
The Caenorhabditis elegans SOMI-1 zinc finger protein and SWI/SNF promote regulation of development by the mir-84 microRNA
2011 StandoutNobel
Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways
2005 StandoutNobel
Cancer stem cells revisited
2017 Standout
Fc Receptors and Their Role in Immune Regulation and Autoimmunity
2005
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
Upstream and downstream of mTOR
2004 Standout
Metazoan MicroRNAs
2018 Standout
Polycomb Group Proteins: Multi-Faceted Regulators of Somatic Stem Cells and Cancer
2010
β-Arrestin1 Mediates Insulin-like Growth Factor 1 (IGF-1) Activation of Phosphatidylinositol 3-Kinase (PI3K) and Anti-apoptosis
2003 StandoutNobel
MicroRNA therapeutics: towards a new era for the management of cancer and other diseases
2017 Standout
The roles of PTEN in development, physiology and tumorigenesis in mouse models: a tissue-by-tissue survey
2008 StandoutNobel
Clinical Effect of Point Mutations in Myelodysplastic Syndromes
2011 Standout
The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow
2011 StandoutNobel
Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia
2013 Standout
Applications of CRISPR technologies in research and beyond
2016 StandoutNobel
Pten inactivation alters peripheral B lymphocyte fate and reconstitutes CD19 function
2003
BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1
2003 StandoutNobel
Phosphoinositides in cell regulation and membrane dynamics
2006 StandoutNature
Concerted action of Helios and Ikaros controls the expression of the inositol 5‐phosphatase SHIP
2010
A decade of exploring the cancer epigenome — biological and translational implications
2011 Standout
Regulatory networks defining EMT during cancer initiation and progression
2013 Standout
The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche
2010
Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
2013 Standout
β-Arrestin2 mediates the initiation and progression of myeloid leukemia
2012 StandoutNobel
Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production
2003 StandoutNobel
PD-1 Inhibits Antiviral Immunity at the Effector Phase in the Liver
2003 StandoutNobel
Isolating gene-corrected stem cells without drug selection
2005 StandoutNobel
Acute Myeloid Leukemia
2015 Standout
Binding to Nonmethylated CpG DNA Is Essential for Target Recognition, Transactivation, and Myeloid Transformation by an MLL Oncoprotein
2004
Apoptosis: A Review of Programmed Cell Death
2007 Standout
PD-L1/B7H-1 Inhibits the Effector Phase of Tumor Rejection by T Cell Receptor (TCR) Transgenic CD8+ T Cells
2004 StandoutNobel
CD150 Association with Either the SH2-Containing Inositol Phosphatase or the SH2-Containing Protein Tyrosine Phosphatase Is Regulated by the Adaptor Protein SH2D1A
2001
A Crucial Role for the p110δ Subunit of Phosphatidylinositol 3-Kinase in B Cell Development and Activation
2002
Iterative in Situ Click Chemistry Assembles a Branched Capture Agent and Allosteric Inhibitor for Akt1
2011 StandoutNobel
Mutations in epigenetic modifiers in the pathogenesis and therapy of acute myeloid leukemia
2013
Critical Roles of Pten in B Cell Homeostasis and Immunoglobulin Class Switch Recombination
2003 StandoutNobel
The prognostic and functional role of microRNAs in acute myeloid leukemia
2010
New mutations and pathogenesis of myeloproliferative neoplasms
2011
Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation
2010
T-Independent Immune Response: New Aspects of B Cell Biology
2000 StandoutScienceNobel
Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2, and DNMT3A
2011
Cellular Function of Phosphoinositide 3-Kinases: Implications for Development, Immunity, Homeostasis, and Cancer
2001
Decoding the Patterns of Self and Nonself by the Innate Immune System
2002 StandoutScience
Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells
2010 StandoutNobel
Prognostic Significance ofASXL1Mutations in Patients With Myelodysplastic Syndromes
2011
In vivo hematopoietic stem cell modification by mRNA delivery
2023 StandoutScienceNobel
Generation of functional platelets from human embryonic stem cells in vitro via ES-sacs, VEGF-promoted structures that concentrate hematopoietic progenitors
2008
ASXL1 mutation correction by CRISPR/Cas9 restores gene function in leukemia cells and increases survival in mouse xenografts
2015
Hydronephrosis associated with antiurothelial and antinuclear autoantibodies in BALB/c-Fcgr2b −/− Pdcd1 −/− mice
2005 StandoutNobel
Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation
2012 StandoutNobel
The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia
2016 Standout
Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten
2004 StandoutNobel
PD-1 and Its Ligands in Tolerance and Immunity
2008 Standout
Immune Inhibitory Receptors
2000 Science
Works of Nicolas Pineault being referenced
Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells throughout murine hematopoietic ontogeny
2002
Candidate Genes for Expansion and Transformation of Hematopoietic Stem Cells by NUP98-HOX Fusion Genes
2007
Efficient in vitro megakaryocyte maturation using cytokine cocktails optimized by statistical experimental design
2005
Hox Genes: From Leukemia to Hematopoietic Stem Cell Expansion
2005
Loss-of-function Additional sex combs like 1 mutations disrupt hematopoiesis but do not cause severe myelodysplasia or leukemia
2009
A Dual Role for Src Homology 2 Domain–Containing Inositol-5-Phosphatase (Ship) in Immunity
2000
Induction of acute myeloid leukemia in mice by the human leukemia-specific fusion gene NUP98-HOXD13 in concert with Meis1
2003
Differential and Common Leukemogenic Potentials of Multiple NUP98-Hox Fusion Proteins Alone or with Meis1
2004