Citation Impact
Citing Papers
Notch signalling controls pancreatic cell differentiation
1999 StandoutNatureNobel
The p48 DNA-binding subunit of transcription factor PTF1 is a new exocrine pancreas-specific basic helix-loop-helix protein.
1996
Conversion of Xenopus Ectoderm into Neurons by NeuroD, a Basic Helix-Loop-Helix Protein
1995 Science
Direct conversion of fibroblasts to functional neurons by defined factors
2010 StandoutNatureNobel
Glimpses of allostery in the control of eukaryotic gene expression
1993
An integrated encyclopedia of DNA elements in the human genome
2012 StandoutNature
Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites
1993
Conserved sequence motifs in the small subunit of human general transcription factor TFIIE
1991 Nature
A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion
1993 StandoutNobel
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
White collar 2,a partner in blue-light signal transduction, controlling expression of light-regulated genes in Neurospora crassa
1997
Mechanism of transcriptional activation by Sp1: Evidence for coactivators
1990
Laboratory evolution of peroxide-mediated cytochrome P450 hydroxylation
1999 StandoutNatureNobel
Chromatin remodeling as a guide to transcriptional regulatory networks in mammals
2003
Mad: A heterodimeric partner for Max that antagonizes Myc transcriptional activity
1993
RAP1 protein interacts with yeast telomeres in vivo: Overproduction alters telomere structure and decreases chromosome stability
1990
Completion of the entire hepatitis C virus life cycle in genetically humanized mice
2013 StandoutNatureNobel
New light on Myc and Myb. Part I. Myc.
1990
Amplification efficiency: linking baseline and bias in the analysis of quantitative PCR data
2009 Standout
Analysis of Sp1 in vivo reveals mutiple transcriptional domains, including a novel glutamine-rich activation motif
1988
The Cold Shock Domain Protein LIN-28 Controls Developmental Timing in C. elegans and Is Regulated by the lin-4 RNA
1997 StandoutNobel
A Mutant Drosophila Homolog of Mammalian Clock Disrupts Circadian Rhythms and Transcription of period and timeless
1998 StandoutNobel
The Hox-1.3 homeo box protein is a sequence-specific DNA-binding phosphoprotein.
1989
Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain
1993 Nature
Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties
1992 StandoutNobel
O-glycosylation of eukaryotic transcription factors: Implications for mechanisms of transcriptional regulation
1988
MUSCLE: multiple sequence alignment with high accuracy and high throughput
2004 Standout
COMPASS: A Tool for Comparison of Multiple Protein Alignments with Assessment of Statistical Significance
2003
Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein
1993 Standout
The origin of pattern and polarity in the Drosophila embryo
1992 StandoutNobel
A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B all
1990 Nobel
Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping
1990 StandoutNature
A mediator required for activation of RNA polymerase II transcription in vitro
1991 StandoutNatureNobel
Runaway telomere elongation caused by telomerase RNA gene mutations
1995 StandoutNatureNobel
Structure and functional properties of human general transcription factor IIE
1991 Nature
Control of telomere growth by interactions of RAP1 with the most distal telomeric repeats
1996 StandoutNatureNobel
PAS is a dimerization domain common to Drosophila Period and several transcription factors
1993 StandoutNatureNobel
Transcription factor ATF interacts with the TATA factor to facilitate establishment of a preinitiation complex
1988
Interactions of coiled coils in transcription factors: where is the specificity?
1993
Patterning of the Caenorhabditis elegans head region by the Pax-6 family member vab-3
1995 StandoutNatureNobel
Regulation of the mevalonate pathway
1990 StandoutNature
Communication Between Mitochondria and the Nucleus in Regulation of Cytochrome Genes in the Yeast Saccharomyces cerevisiae
1989
The war of the whorls: genetic interactions controlling flower development
1991 StandoutNature
Isoprenylation in regulation of signal transduction by G-protein-coupled receptor kinases
1992 StandoutNatureNobel
A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells
1990
Switching and Signaling at the Telomere
2001 StandoutNobel
Synergistic activation and repression of transcription by Drosophila homeobox proteins
1989
PAX6 gene dosage effect in a family with congenital cataracts, aniridia, anophthalmia and central nervous system defects
1994 Standout
Fluorescence ratio imaging of cyclic AMP in single cells
1991 StandoutNatureNobel
floricaula: A homeotic gene required for flower development in antirrhinum majus
1990
HIF-1 Regulates Cytochrome Oxidase Subunits to Optimize Efficiency of Respiration in Hypoxic Cells
2007 StandoutNobel
Rescue of bicoid mutant Drosophila embryos by Bicoid fusion proteins containing heterologous activating sequences
1989 StandoutNatureNobel
SPXX, a frequent sequence motif in gene regulatory proteins
1989
Dual role of TFIIH in DNA excision repair and in transcription by RNA polymerase II
1994 StandoutNatureNobel
A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II
1994 StandoutNobel
Effects of activation-defective TBP mutations on transcription initiation in yeast
1994 StandoutNatureNobel
Quantitative Models of the Mechanisms That Control Genome-Wide Patterns of Transcription Factor Binding during Early Drosophila Development
2011
Regulation of gene expression by transfected subunits of cAMP‐dependent protein kinase
1990
Homeodomain-DNA recognition
1994 StandoutNobel
Genomic structure, evolutionary conservation and aniridia mutations in the human PAX6 gene
1992
The POU-specific domain of Pit-1 is essential for sequence-specific, high affinity DNA binding and DNA-dependent Pit-1—Pit-1 interactions
1990
Possible cross-regulation of phosphate and sulfate metabolism in Saccharomyces cerevisiae.
1992
Activation and repression of transcription by homoeodomain-containing proteins that bind a common site
1988 Nature
Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum response element
1988
The Drosophila single-minded gene encodes a helix-loop-helix protein that acts as a master regulator of CNS midline development
1991
The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES Cells
2003 StandoutNobel
Isolation and characterization of the Drosophila gene encoding the TATA box binding protein, TFIID
1990
Crystal Structures of a Complexed and Peptide-Free Membrane Protein–Binding Domain: Molecular Basis of Peptide Recognition by PDZ
1996 StandoutNobel
Universal control mechanism regulating onset of M-phase
1990 StandoutNatureNobel
Organic Compounds from Diesel Exhaust Particles Elicit a Proinflammatory Response in Human Airway Epithelial Cells and Induce Cytochrome p450 1A1 Expression
2001
Multiple genes encode nuclear factor 1-like proteins that bind to the promoter for 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
1988
DNA Repair Helicase: a Component of BTF2 (TFIIH) Basic Transcription Factor
1993 Science
PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1.
1991
Heterodimerization between light-regulated and ubiquitously expressed Arabidopsis GBF bZIP proteins.
1992
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
1997 Standout
Differences and Similarities in DNA-Binding Preferences of MyoD and E2A Protein Complexes Revealed by Binding Site Selection
1990 Science
Discrimination between related DNA sites by a single amino acid residue of Myc-related basic-helix-loop-helix proteins.
1992
Xenopus Y-box transcription factors: molecular cloning, functional analysis and developmental regulation.
1990
Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus
1990 Standout
Max: A Helix-Loop-Helix Zipper Protein That Forms a Sequence-Specific DNA-Binding Complex with Myc
1991 StandoutScience
Novel cysteine-rich motif and homeodomain in the product of the Caenorhabditis elegans cell lineage gene lin-II
1990 StandoutNatureNobel
PER Protein Interactions and Temperature Compensation of a Circadian Clock in Drosophila
1995 StandoutScienceNobel
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.
1995 StandoutNobel
A single internalization signal from the di-leucine family is critical for constitutive endocytosis of the type II TGF-β receptor
2001
Purification of a NF1-like DNA-binding protein from rat liver and cloning of the corresponding cDNA.
1988
Mechanisms of DNA Excision Repair
1994 StandoutScienceNobel
Adenylyl Cyclase Amino Acid Sequence: Possible Channel- or Transporter-Like Structure
1989 StandoutScienceNobel
Nucleotide sequence of the Pseudomonas putida cytochrome P-450cam gene and its expression in Escherichia coli.
1986
Identification of functional domains of the aryl hydrocarbon receptor nuclear translocator protein (ARNT).
1994
The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments
2009 Standout
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
The Zta trans-activator protein stabilizes TFIID association with promoter DNA by direct protein-protein interaction.
1991
Interaction Cloning: Identification of a Helix-Loop-Helix Zipper Protein that Interacts with c-Fos
1992 Science
Asymmetric DNA Bending Induced by the Yeast Multifunctional Factor TUF
1989
A protein involved in minichromosome maintenance in yeast binds a transcriptional enhancer conserved in eukaryotes.
1989
Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development
1993
The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript.
1993
The HIP1 binding site is required for growth regulation of the dihydrofolate reductase gene promoter.
1992
The HIP1 Binding Site Is Required for Growth Regulation of the Dihydrofolate Reductase Gene Promoter
1992
Novel Jun- and Fos-related proteins in Drosophila are functionally homologous to enhancer factor AP-1.
1988
Coactivators for a proline-rich activator purified from the multisubunit human TFIID complex.
1991
Cloning and characterization of PSF, a novel pre-mRNA splicing factor.
1993
Identification of Functional Domains of the Aryl Hydrocarbon Receptor Nuclear Translocator Protein (ARNT)
1994
The DNA binding subunit of NF-κB is identical to factor KBF1 and homologous to the rel oncogene product
1990
Evidence for a nuclear factor(s), IRF-1, mediating induction and silencing properties to human IFN-beta gene regulatory elements.
1988
Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins
1989 StandoutScience
mTFE3, an X-Linked Transcriptional Activator Containing Basic Helix-Loop-Helix and Zipper Domains, Utilizes the Zipper To Stabilize Both DNA Binding and Multimerization
1992
Isolation of a rel -related Human cDNAThat Potentially Encodes the 65-kD Subunit of NF-κB
1991 Science
Transcriptional activation in yeast by the proline-rich activation domain of human CTF1.
1993
Cooperative Interactions Between the Caenorhabditis elegans Homeoproteins UNC-86 and MEC-3
1993 StandoutScienceNobel
A cAMP response element in the beta 2-adrenergic receptor gene confers transcriptional autoregulation by cAMP.
1990 StandoutNobel
The Mating of a Fly
1994 StandoutScienceNobel
Characterization of the Epstein-Barr virus BZLF1 protein transactivation domain
1992
Structural organization of the human neuronal nitric oxide synthase gene (NOS1)
1994
Structure and function of telomeres
1991 StandoutNatureNobel
Zyxin and cCRP: two interactive LIM domain proteins associated with the cytoskeleton.
1992
Tissue-specific RNA splicing generates an ankyrin-like domain that affects the dimerization and DNA-binding properties of a bHLH protein.
1993
The ubiquitous octamer-binding protein Oct-1 contains a POU domain with a homeo box subdomain.
1988
Consequences of heteromeric interactions among helix-loop-helix proteins.
1993
ß-Arrestin 2 Mediates Endocytosis of Type III TGF-ß Receptor and Down-Regulation of Its Signaling
2003 StandoutScienceNobel
Cloning and expression of AP-2, a cell-type-specific transcription factor that activates inducible enhancer elements.
1988
TFE3: a helix-loop-helix protein that activates transcription through the immunoglobulin enhancer muE3 motif.
1990
Works of Nicolas Mermod being referenced
The proline-rich transcriptional activator of CTF/NF-I is distinct from the replication and DNA binding domain
1989
Transforming growth factor‐β: The breaking open of a black box
1997
High-throughput SELEX–SAGE method for quantitative modeling of transcription-factor binding sites
2002
Enhancer binding factors AP-4 and AP-1 act in concert to activate SV40 late transcription in vitro
1988 Nature
A family of human CCAAT-box-binding proteins active in transcription and DNA replication: cloning and expression of multiple cDNAs
1988 Nature
Statistical significance of quantitative PCR
2007
Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity.
1990
An Autoregulatory Loop ControllingCYP1A1Gene Expression: Role of H2O2and NFI
1999
Proteins bound at adjacent DNA elements act synergistically to regulate human proenkephalin cAMP inducible transcription.
1988
Regulation of Gene Expression by Interferons: Control of H-2 Promoter Responses
1988 Science
Transcription of the TOL plasmid toluate catabolic pathway operon of Pseudomonas putida is determined by a pair of co-ordinately and positively regulated overlapping promoters.
1984