Citation Impact
Citing Papers
Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
2010 StandoutScienceNobel
K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac
2015 Science
Radial stretch reveals distinct populations of mechanosensitive mammalian somatosensory neurons
2008 StandoutNobel
Cytoplasmic ankyrin repeats of transient receptor potential A1 (TRPA1) dictate sensitivity to thermal and chemical stimuli
2011 StandoutNobel
Crystal Structure of the Human K2P TRAAK, a Lipid- and Mechano-Sensitive K + Ion Channel
2012 ScienceNobel
PIEZOs mediate neuronal sensing of blood pressure and the baroreceptor reflex
2018 StandoutScienceNobel
Serotonin Transporter Genetic Variation and the Response of the Human Amygdala
2002 StandoutScience
Control of sensory neuron excitability by serotonin involves 5HT2C receptors and Ca2+-activated chloride channels
2016
Dynamic regulation of TREK1 gating by Polycystin 2 via a Filamin A-mediated cytoskeletal Mechanism
2017
Removal of the mechanoprotective influence of the cytoskeleton reveals PIEZO1 is gated by bilayer tension
2016
Piezo1 Channels Are Inherently Mechanosensitive
2016 StandoutNobel
Piezo1 in Smooth Muscle Cells Is Involved in Hypertension-Dependent Arterial Remodeling
2015
Functional Role for Piezo1 in Stretch-evoked Ca2+ Influx and ATP Release in Urothelial Cell Cultures
2014
Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors
2014 StandoutNatureNobel
Merkel Cells Activate Sensory Neural Pathways through Adrenergic Synapses
2018 StandoutNobel
Discoveries in structure and physiology of mechanically activated ion channels
2020 StandoutNatureNobel
X-Ray Structure of Acid-Sensing Ion Channel 1–Snake Toxin Complex Reveals Open State of a Na+-Selective Channel
2014 StandoutNobel
The mechano-gated K2P channel TREK-1
2008
Mechanisms of sensory transduction in the skin
2007 Nature
Acid-sensing Ion Channels in Sensory Perception
2007
A phospholipid sensor controls mechanogating of the K+ channel TREK‐1
2004
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
2016 StandoutNatureNobel
TRPM8, but not TRPA1, is required for neural and behavioral responses to acute noxious cold temperatures and cold-mimetics in vivo
2010
Phenotyping sensory nerve endings in vitro in the mouse
2009
Physiology of Cell Volume Regulation in Vertebrates
2009
Mechanical, thermal and formalin-induced nociception is differentially altered in 5-HT1A−/−, 5-HT1B−/−, 5-HT2A−/−, 5-HT3A−/− and 5-HTT−/− knock-out male mice
2007 StandoutNobel
The Purified Mechanosensitive Channel TREK-1 Is Directly Sensitive to Membrane Tension
2013
Piezo proteins are pore-forming subunits of mechanically activated channels
2012 StandoutNatureNobel
Acid-Sensing Ion Channels (ASICs): Pharmacology and implication in pain
2010
Eating disorder and epilepsy in mice lacking 5-HT2C serotonin receptors
1995 StandoutNatureNobel
The human raphe nuclei and the serotonergic system
2003
Polycystin-1 and -2 Dosage Regulates Pressure Sensing
2009
A new wave of serotonin receptors
1993 StandoutNobel
Characterization of Acid-sensing Ion Channels in Dorsal Horn Neurons of Rat Spinal Cord
2004
New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor
1994 StandoutNatureNobel
A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain
2011 StandoutNatureNobel
Mechanically Activated Ion Channels
2015 StandoutNobel
Molecular mechanisms of mechanotransduction in mammalian sensory neurons
2011
Recent advances in the electrophysiological characterization of 5-HT3 receptors
1992
Serotonin Receptor 5-HT2BMediates Serotonin-Induced Mechanical Hyperalgesia
2011
Knockout of the ASIC2 channel in mice does not impair cutaneous mechanosensation, visceral mechanonociception and hearing
2004
Descending facilitatory control of mechanically evoked responses is enhanced in deep dorsal horn neurones following peripheral nerve injury
2004
Serotonin receptor mRNA expression in rat dorsal root ganglion neurons
2003
A role of PIEZO1 in iron metabolism in mice and humans
2021 StandoutNobel
The force-from-lipid (FFL) principle of mechanosensitivity, at large and in elements
2014
Piezo2 is the major transducer of mechanical forces for touch sensation in mice
2014 StandoutNatureNobel
A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain
2019 StandoutNobel
Mammalian Mechanoelectrical Transduction: Structure and Function of Force-Gated Ion Channels
2019
TRPM8 Is Required for Cold Sensation in Mice
2007 StandoutNobel
Structure of the mechanically activated ion channel Piezo1
2017 StandoutNatureNobel
TRPV1 structures in distinct conformations reveal activation mechanisms
2013 StandoutNatureNobel
Transmembrane Helix Straightening and Buckling Underlies Activation of Mechanosensitive and Thermosensitive K2P Channels
2014
Molecular basis of infrared detection by snakes
2010 StandoutNatureNobel
Depletion of endogenous spinal 5-HT attenuates the behavioural hypersensitivity to mechanical and cooling stimuli induced by spinal nerve ligation
2006
Mechanosensitive ion channels and the peptide inhibitor GsMTx-4: History, properties, mechanisms and pharmacology
2006
Modifying the Subunit Composition of TASK Channels Alters the Modulation of a Leak Conductance in Cerebellar Granule Neurons
2005
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
What we can do and what we cannot do with fMRI
2008 StandoutNature
Acid-sensing ion channels: advances, questions and therapeutic opportunities
2006
Pungent agents from Szechuan peppers excite sensory neurons by inhibiting two-pore potassium channels
2008 StandoutNobel
HTR7 Mediates Serotonergic Acute and Chronic Itch
2015
Mammalian somatosensory mechanotransduction
2009
SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel
2014 StandoutNobel
The menthol receptor TRPM8 is the principal detector of environmental cold
2007 StandoutNatureNobel
Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel
2014 NatureNobel
PIEZO2 in sensory neurons and urothelial cells coordinates urination
2020 StandoutNatureNobel
TASK-3 Two-Pore Domain Potassium Channels Enable Sustained High-Frequency Firing in Cerebellar Granule Neurons
2007
The role of Drosophila Piezo in mechanical nociception
2012 StandoutNatureNobel
Spider toxins activate the capsaicin receptor to produce inflammatory pain
2006 StandoutNatureNobel
The receptor site of the spider toxin PcTx1 on the proton‐gated cation channel ASIC1a
2005
Nociceptors—Noxious Stimulus Detectors
2007
Piezo2 senses airway stretch and mediates lung inflation-induced apnoea
2016 StandoutNatureNobel
Central Sensitization: A Generator of Pain Hypersensitivity by Central Neural Plasticity
2009 Standout
Pain-associated signals, acidosis and lysophosphatidic acid, modulate the neuronal K2P2.1 channel
2008
Neurosensory mechanotransduction
2008 StandoutNobel
LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength
2016 StandoutNobel
Nociceptors: the sensors of the pain pathway
2010 StandoutNobel
Sensing pressure with ion channels
2012
Uropathic Observations in Mice Expressing a Constitutively Active Point Mutation in the 5-HT3AReceptor Subunit
2004 StandoutNobel
Ion channels involved in cold detection in mammals: TRP and non-TRP mechanisms
2009
Eukaryotic Mechanosensitive Channels
2010 Nobel
Structure and activity of the acid-sensing ion channels
2012
Mechanosensitive Ion Channels: Structural Features Relevant to Mechanotransduction Mechanisms
2020
Impaired retention of spatial memory after transection of longitudinally oriented axons of hippocampal CA3 pyramidal cells
2002 StandoutNobel
The mechanosensitive ion channel TRAAK is localized to the mammalian node of Ranvier
2019 Nobel
Molecular and Cellular Limits to Somatosensory Specificity
2008
Inactivation of a Serotonin-Gated Ion Channel by a Polypeptide Toxin from Marine Snails
1998 StandoutScienceNobel
Nervous system distribution of the serotonin 5-HT3 receptor mRNA.
1993 StandoutNobel
Structure, function, and pharmacology of acid-sensing ion channels (ASICs): focus on ASIC1a.
2010
Interneurons of the hippocampus
1998 Standout
Gain-of-function mutations in the mechanically activated ion channel PIEZO2 cause a subtype of Distal Arthrogryposis
2013 StandoutNobel
Stretch-Activated Ion Channels: What Are They?
2010
Mechanosensitivity is mediated directly by the lipid membrane in TRAAK and TREK1 K + channels
2014 Nobel
Piezo1, a mechanically activated ion channel, is required for vascular development in mice
2014 StandoutNobel
Two amino acid residues determine 2-APB sensitivity of the ion channels TRPV3 and TRPV4
2009 StandoutNobel
Feeling the hidden mechanical forces in lipid bilayer is an original sense
2014
Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation
2018 StandoutNobel
Oxaliplatin‐induced cold hypersensitivity is due to remodelling of ion channel expression in nociceptors
2011
Pharmacology of the Na v 1.1 domain IV voltage sensor reveals coupling between inactivation gating processes
2017 StandoutNobel
Asymmetric mechanosensitivity in a eukaryotic ion channel
2017
Quantitation of 5HT3 receptors in forebrain of serotonin transporter deficient mice
2004
Xerocytosis is caused by mutations that alter the kinetics of the mechanosensitive channel PIEZO1
2013
Structural insights into TRPM8 inhibition and desensitization
2019 StandoutScienceNobel
How ion channels sense mechanical force: insights from mechanosensitive K2P channels TRAAK, TREK1, and TREK2
2015
Lys49 myotoxin from the Brazilian lancehead pit viper elicits pain through regulated ATP release
2017 StandoutNobel
Serotonergic Modulation of Neurotransmission in the Rat Basolateral Amygdala
1999
Works of Nicolas Guy being referenced
Acid-Sensing Ion Channel 2 Is Important for Retinal Function and Protects against Light-Induced Retinal Degeneration
2004
AKAP150, a switch to convert mechano‐, pH‐ and arachidonic acid‐sensitive TREK K+ channels into open leak channels
2006
The mechano‐activated K+ channels TRAAK and TREK‐1 control both warm and cold perception
2009
TREK‐1, a K+ channel involved in neuroprotection and general anesthesia
2004
TREK‐1, a K+ channel involved in polymodal pain perception
2006
Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype
2006
Cross‐talk between the mechano‐gated K 2P channel TREK‐1 and the actin cytoskeleton
2005
Altered acetylcholine, bradykinin and cutaneous pressure‐induced vasodilation in mice lacking the TREK1 potassium channel: the endothelial link
2007
The 5-HT3Subtype of Serotonin Receptor Contributes to Nociceptive Processing via a Novel Subset of Myelinated and Unmyelinated Nociceptors
2002 StandoutNobel
Proximal renal tubular acidosis in TASK2 K + channel-deficient mice reveals a mechanism for stabilizing bicarbonate transport
2004
Serotonin facilitates GABAergic transmission in the CA1 region of rat hippocampus in vitro.
1991
Role of TASK2 Potassium Channels Regarding Volume Regulation in Primary Cultures of Mouse Proximal Tubules
2003