Citation Impact
Citing Papers
Insulin-like growth factor 1 treatment extends longevity in a mouse model of human premature aging by restoring somatotroph axis function
2010
Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation
2013 StandoutScience
Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota
2012 StandoutScience
BMN 673, a Novel and Highly Potent PARP1/2 Inhibitor for the Treatment of Human Cancers with DNA Repair Deficiency
2013
PARP inhibitors: Synthetic lethality in the clinic
2017 StandoutScience
Mismatch Repair-dependent Iterative Excision at Irreparable O6-Methylguanine Lesions in Human Nuclear Extracts
2006 StandoutNobel
An Integrated Approach for Analysis of the DNA Damage Response in Mammalian Cells
2015 StandoutNobel
The DNA-damage response in human biology and disease
2009 StandoutNature
Tipin-Replication Protein A Interaction Mediates Chk1 Phosphorylation by ATR in Response to Genotoxic Stress
2010 StandoutNobel
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
2005 StandoutNature
BRCA2 Is Required for Homology-Directed Repair of Chromosomal Breaks
2001
A view on drug resistance in cancer
2019 StandoutNature
Splitting the ATM: distinct repair and checkpoint defects in ataxia–telangiectasia
1998
Genetic Disorders Associated with Cancer Predisposition and Genomic Instability
1999
Cell-cycle checkpoints and cancer
2004 StandoutNature
BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage
2002
Regulation of DNA repair in hypoxic cancer cells
2007
The genetics of ageing
2010 StandoutNature
Reconstitution of Human Claspin-mediated Phosphorylation of Chk1 by the ATR (Ataxia Telangiectasia-mutated and Rad3-related) Checkpoint Kinase
2009 StandoutNobel
Saccharomyces cerevisiae Rad9 Acts as a Mec1 Adaptor to Allow Rad53 Activation
2005
The DNA Damage Response Kinases DNA-dependent Protein Kinase (DNA-PK) and Ataxia Telangiectasia Mutated (ATM) Are Stimulated by Bulky Adduct-containing DNA
2011 StandoutNobel
Intrinsic disorder in scaffold proteins: Getting more from less
2008
Bleomycins: towards better therapeutics
2005
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
2005 StandoutNature
Hallmarks of aging: An expanding universe
2023 Standout
Genetic instabilities in human cancers
1998 StandoutNature
Nuclear lamins and laminopathies
2011
ATM: from gene to function
1998
ATM and related protein kinases: safeguarding genome integrity
2003 Standout
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
2005 StandoutNature
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
2011 StandoutNature
ATM, a central controller of cellular responses to DNA damage
2001
Regulation of Ionizing Radiation-induced Rad52 Nuclear Foci Formation by c-Abl-mediated Phosphorylation
2002
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
2011 StandoutNatureNobel
A DNA damage checkpoint response in telomere-initiated senescence
2003 StandoutNature
Immunogenicity of induced pluripotent stem cells
2011 StandoutNature
Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response
2012
The Chk2 protein kinase
2004
Functional links between telomeres and proteins of the DNA-damage response
2004
Identification of a defect in DNA ligase IV in a radiosensitive leukaemia patient
1999
Progeria: A Paradigm for Translational Medicine
2014
Progeria syndromes and ageing: what is the connection?
2010
ATM, ATR and DNA-PK: initiators of the cellular genotoxic stress responses
2003
MEC1-Dependent Redistribution of the Sir3 Silencing Protein from Telomeres to DNA Double-Strand Breaks
1999
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
Convergence of the Fanconi Anemia and Ataxia Telangiectasia Signaling Pathways
2002
Recombinational DNA repair and human disease
2002
Chk2 Oligomerization Studied by Phosphopeptide Ligation
2008 StandoutNobel
Human Claspin Is a Ring-shaped DNA-binding Protein with High Affinity to Branched DNA Structures
2004 StandoutNobel
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
γH2AX and cancer
2008
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
2000 StandoutNature
Mechanism of Stimulation of Human DNA Ligase I by the Rad9-Rad1-Hus1 Checkpoint Complex
2006 StandoutNobel
Coupling of Human DNA Excision Repair and the DNA Damage Checkpoint in a Defined in Vitro System
2014 StandoutNobel
Activation and regulation of ATM kinase activity in response to DNA double-strand breaks
2007
Néstor–Guillermo progeria syndrome: A novel premature aging condition with early onset and chronic development caused by BANF1 mutations
2011
The DNA damage response: putting checkpoints in perspective
2000 StandoutNature
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
2003 StandoutNature
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
The role of senescent cells in ageing
2014 StandoutNature
Collaboration of Brca1 and Chk2 in tumorigenesis
2004
Nuclear envelope alterations generate an aging‐like epigenetic pattern in mice deficient in Zmpste24 metalloprotease
2010
The Hallmarks of Aging
2013 Standout
DNA ligases in the repair and replication of DNA
2000
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from BRCA Mutation Carriers
2009 Standout
Loss of ATM sensitizes against O6-methylguanine triggered apoptosis, SCEs and chromosomal aberrations
2004
Proteomics to study genes and genomes
2000 StandoutNature
The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator
2012 StandoutNobel
Requirement of the MRN complex for ATM activation by DNA damage
2003
ATP Activates Ataxia-Telangiectasia Mutated (ATM) in Vitro
2003
The roles of BRCA1 and BRCA2 and associated proteins in the maintenance of genomic stability
2006
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis
2011 StandoutNobel
Radiosensitization and DNA repair inhibition by the combined use of novel inhibitors of DNA-dependent protein kinase and poly(ADP-ribose) polymerase-1.
2003
The Posttranslational Processing of Prelamin A and Disease
2009
Molecular Pathology of Laminopathies
2021
Ataxia telangiectasia mutated (Atm) is not required for telomerase-mediated elongation of short telomeres
2006 StandoutNobel
Quality Control by DNA Repair
1999 StandoutScienceNobel
Prelamin A Acts to Accelerate Smooth Muscle Cell Senescence and Is a Novel Biomarker of Human Vascular Aging
2010
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
Homology-directed dna repair, mitomycin-c resistance, and chromosome stability is restored with correction of a Brca1 mutation.
2001
Progress and trends in the development of therapies for Hutchinson–Gilford progeria syndrome
2020
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
Spermidine in health and disease
2018 StandoutScience
Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses
2003
Four faces of cellular senescence
2011 Standout
Requirement of ATM-Dependent Phosphorylation of Brca1 in the DNA Damage Response to Double-Strand Breaks
1999 Science
The protein kinase Akt/PKB regulates both prelamin A degradation and Lmna gene expression
2013
Splicing-Directed Therapy in a New Mouse Model of Human Accelerated Aging
2011
Cancer Genome Landscapes
2013 StandoutScience
Mouse Models to Disentangle the Hallmarks of Human Aging
2018
Rejoining Kinetics of DNA Single- and Double-Strand Breaks in Normal and DNA Ligase-Deficient Cells after Exposure to Ultraviolet C and Gamma Radiation: An Evaluation of Ligating Activities Involved in Different DNA Repair Processes
1999
Identification and Characterization of a Novel and Specific Inhibitor of the Ataxia-Telangiectasia Mutated Kinase ATM
2004
Direct Cellular Responses to Platinum-Induced DNA Damage
2007
Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase
2010 StandoutNobel
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
2004 StandoutNobel
Works of Nicolas Foray being referenced
A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein
2003
DNA double-strand break repair defects in syndromes associated with acute radiation response: At least two different assays to predict intrinsic radiosensitivity?
2008
Radiation-induced DNA double-strand breaks and the radiosensitivity of human cells: A closer look
1997
The ratio of single- to double-strand DNA breaks and their absolute values determine cell death pathway
2001
Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging
2008
Cross-Resistance to Ionizing Radiation in a Murine Leukemic Cell Line Resistant tocis-Dichlorodiammineplatinum(II): Role of Ku Autoantigen
1999
Gamma-rays-induced death of human cells carrying mutations of BRCA1 or BRCA2
1999
Dose-rate effect on induction and repair rate of radiation-induced DNA double-strand breaks in a normal and an ataxia telangiectasia human fibroblast cell line
1995
Defective repair of DNA double-strand breaks and chromosome damage in fibroblasts from a radiosensitive leukemia patient.
1995
Constitutive Association of BRCA1 and c-Abl and Its ATM-Dependent Disruption after Irradiation
2002
Hypersensitivity of ataxia telangiectasia fibroblasts to ionizing radiation is associated with a repair deficiency of DNA double-strand breaks
1997
Radiosensitivity in Nijmegen Breakage Syndrome cells is attributable to a repair defect and not cell cycle checkpoint defects.
2000
A DNA double-strand break defective fibroblast cell line (180BR) derived from a radiosensitive patient represents a new mutant phenotype.
1997