Citation Impact
Citing Papers
TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo
2010 StandoutNobel
Induction of natural competence in Streptococcus pneumoniae triggers lysis and DNA release from a subfraction of the cell population
2002
Biochemistry of B Lymphocyte Activation
1993
Genetic manipulation of Patescibacteria provides mechanistic insights into microbial dark matter and the epibiotic lifestyle
2023 StandoutNobel
Re-establishing immunological self-tolerance in autoimmune disease
2012 StandoutNobel
Identification of a signal for rapid export of proteins from the nucleus
1995 StandoutNobel
Activation of Atypical Protein Kinase C ζ by Caspase Processing and Degradation by the Ubiquitin-Proteasome System
2000 StandoutNobel
Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus
2003 Standout
Negative regulation of T-cell receptor signalling by tyrosine protein kinase p50csk
1993 Nature
Inhibitors of Protein Tyrosine Phosphatases: Next‐Generation Drugs?
2005
The when and how of Src regulation
1993
Regulation, substrates and functions of src
1996
Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis
2016 StandoutNobel
Signalling by the p60 family of protein—tyrosine kinases
1995
Smad-dependent and Smad-independent pathways in TGF-β family signalling
2003 StandoutNature
Substrate Specificities of Caspase Family Proteases
1997
β2-Adrenergic Receptor-induced p38 MAPK Activation Is Mediated by Protein Kinase A Rather than by Gi or Gβγ in Adult Mouse Cardiomyocytes
2000 StandoutNobel
X-linked IAP is a direct inhibitor of cell-death proteases
1997 StandoutNature
Constitutive activation of Src family kinases in mouse embryos that lack Csk
1993
G Protein-coupled Receptors Mediate Two Functionally Distinct Pathways of Tyrosine Phosphorylation in Rat 1a Fibroblasts
1997 StandoutNobel
The Oncogenic Cysteine-rich LIM domain protein Rbtn2 is essential for erythroid development
1994 StandoutNobel
Regulation of B-cell activation by CD45: a question of mechanism
1994
Involvement of the Protein Tyrosine Kinase p56lck in T Cell Signaling and Thymocyte Development
1994
Vertebrate non‐receptor protein–tyrosine kinase families
1996
Mechanism of Polypeptide Translocation into the Endoplasmic Reticulum
1996 StandoutNobel
Identification of Substrates of Human Protein-tyrosine Phosphatase PTPN22
2006
Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates
2019 Standout
Signal Recognition Particle (SRP), a Ubiquitous Initiator of Protein Translocation
1995
Determinants for Membrane Association of the Hepatitis C Virus RNA-dependent RNA Polymerase
2001 StandoutNobel
Disruption of the csk gene, encoding a negative regulator of Src family tyrosine kinases, leads to neural tube defects and embryonic lethality in mice
1993
Signal transduction by lymphocyte antigen receptors
1994 Standout
src-related protein tyrosine kinases and their surface receptors
1993
Signaling—2000 and Beyond
2000 Standout
β-Arrestin1 Interacts with the Catalytic Domain of the Tyrosine Kinase c-SRC
2000 StandoutNobel
Protein tyrosine phosphorylation in T cell signaling
2002
The primary transcriptome of the major human pathogen Helicobacter pylori
2010 StandoutNature
Protein modules and signalling networks
1995 StandoutNature
Genetic Evidence for a Tyrosine Kinase Cascade Preceding the Mitogen-activated Protein Kinase Cascade in Vertebrate G Protein Signaling
1997
Type 1 diabetes
2013 Standout
The Src SH3 Domain Is Required for DNA Synthesis Induced by Platelet-derived Growth Factor and Epidermal Growth Factor
1996
Structure‐function relationships in Src family and related protein tyrosine kinases
1995
β-Arrestin-mediated Recruitment of the Src Family Kinase Yes Mediates Endothelin-1-stimulated Glucose Transport
2001 StandoutNobel
Crosstalk between cAMP-dependent kinase and MAP kinase through a protein tyrosine phosphatase
1999
Biophysical mechanism of T-cell receptor triggering in a reconstituted system
2012 Nature
Role of PTPN22 in type 1 diabetes and other autoimmune diseases
2006
Clonal selection and learning in the antibody system
1996 StandoutNature
Identification of Clonogenic Common Lymphoid Progenitors in Mouse Bone Marrow
1997 Standout
Programmed population control by cell–cell communication and regulated killing
2004 StandoutNatureNobel
Two-component and phosphorelay signal transduction
2000
Increase of Solubility of Foreign Proteins in Escherichia coli by Coproduction of the Bacterial Thioredoxin
1995
Status of genome projects for nonpathogenic bacteria and archaea
2000
A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes
2004
Microbial chemical signaling: a current perspective
2012
Protein Tyrosine Phosphatases in the Human Genome
2004 Standout
Binding of Secretory Precursor Polypeptides to a Translocon Subcomplex Is Regulated by BiP
1997 StandoutNobel
The TGFβ Receptor Activation Process
2001
Signal Sequence Recognition and Protein Targeting to the Endoplasmic Reticulum Membrane
1994
Structural Basis for the Autoinhibition of c-Abl Tyrosine Kinase
2003 Standout
Advanced genetic strategies for recombinant protein expression in Escherichia coli
2004
Role of c-Src Tyrosine Kinase in G Protein-coupled Receptorand Gβγ Subunit-mediated Activation of Mitogen-activated Protein Kinases
1996 StandoutNobel
Caspases: Intracellular Signaling by Proteolysis
1997 Standout
Dosage‐dependent switch from G protein‐coupled to G protein‐independent signaling by a GPCR
2006 StandoutNobel
Molecular Basis of Fc Receptor Function
1994
Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice
1995 StandoutNature
Bacterial transformation: distribution, shared mechanisms and divergent control
2014
NUC-1, aCaenorhabditis elegansDNase II homolog, functions in an intermediate step of DNA degradation during apoptosis
2000 StandoutNobel
Protein tyrosine phosphatases
2002
Inhibitoren der Proteintyrosinphosphatasen: Kandidaten für zukünftige Wirkstoffe?
2005
Early T Lymphocyte Progenitors
1996
Analysis of the binding of the Src homology 2 domain of Csk to tyrosine-phosphorylated proteins in the suppression and mitotic activation of c-Src.
1994
β-Arrestin-Dependent Formation of β 2 Adrenergic Receptor-Src Protein Kinase Complexes
1999 StandoutScienceNobel
Strength of TCR–Peptide/MHC Interactions and In Vivo T Cell Responses
2011 StandoutNobel
Loss of the Protein Tyrosine Phosphatase PTPN22 Reduces Mannan-Induced Autoimmune Arthritis in SKG Mice
2016 StandoutNobel
Commensal Host-Bacterial Relationships in the Gut
2001 StandoutScience
Positive and negative regulation of T-cell activation through kinases and phosphatases
2003
Activation of the Lck tyrosine protein kinase by hydrogen peroxide requires the phosphorylation of Tyr-394.
1995
BiP and Sec63p are required for both co- and posttranslational protein translocation into the yeast endoplasmic reticulum.
1995 StandoutNobel
THE DYNAMICS OF T CELL RECEPTOR SIGNALING: Complex Orchestration and the Key Roles of Tempo and Cooperation
1999
Conserved regulation of the lymphocyte-specific expression oflckin the Fugu and mammals
2002 StandoutNobel
Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase
2013 StandoutNobel
Integrins and Signal Transduction Pathways: the Road Taken
1995 StandoutScience
The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition
2014 Standout
Signal Recognition Particle (SRP), a Ubiquitous Initiator of Protein Translocation
1995
Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease
2014 StandoutScienceNobel
Graded Attenuation of TCR Signaling Elicits Distinct Autoimmune Diseases by Altering Thymic T Cell Selection and Regulatory T Cell Function
2010 StandoutNobel
Focal adhesion kinase in the brain: novel subcellular localization and specific regulation by Fyn tyrosine kinase in mutant mice.
1995 StandoutNobel
Cytokine Signaling Through Nonreceptor Protein Tyrosine Kinases
1995 StandoutScience
Fluorosulfuryl Isocyanate Enabled SuFEx Ligation of Alcohols and Amines
2021 StandoutNobel
Csk suppression of Src involves movement of Csk to sites of Src activity.
1994
Gene Expression Profiling of Helicobacter pylori Reveals a Growth-Phase-Dependent Switch in Virulence Gene Expression
2003
Markedly Different Pathogenicity of Four Immunoglobulin G Isotype-Switch Variants of an Antierythrocyte Autoantibody Is Based on Their Capacity to Interact in Vivo with the Low-Affinity Fcγ Receptor III
2000 StandoutNobel
Csk inhibition of c-Src activity requires both the SH2 and SH3 domains of Src.
1993
Overexpression of csk inhibits acid-induced activation of NHE-3.
1995
Subunits of the Saccharomyces cerevisiae signal recognition particle required for its functional expression.
1994
Free Radicals in the Physiological Control of Cell Function
2002 Standout
Induction of Hypoxia-Inducible Factor-1, Erythropoietin, Vascular Endothelial Growth Factor, and Glucose Transporter-1 by Hypoxia: Evidence Against a Regulatory Role for Src Kinase
1997 StandoutNobel
Activation of p56lck by p72syk through Physical Association and N-Terminal Tyrosine Phosphorylation†
1994
Works of Nicholas Flint being referenced
Purification and characterization of an activated form of the protein tyrosine kinase Lck from an Escherichia coli expression system
1994
Domain organization and molecular characterization of 13 two-component systems identified by genome sequencing of Streptococcus pneumoniae
1999
The 68 kDa protein of signal recognition particle contains a glycine‐rich region also found in certain RNA‐binding proteins
1990
Microarray-Based Identification of a Novel Streptococcus pneumoniae Regulon Controlled by an Autoinduced Peptide
2000
Purification and characterization of recombinant human p50csk protein-tyrosine kinase from an Escherichia coli expression system overproducing the bacterial chaperones GroES and GroEL.
1995
The human p50csk tyrosine kinase phosphorylates p56lck at Tyr-505 and down regulates its catalytic activity.
1992