Standout Papers

The status of platinum anticancer drugs in the clinic and in clinical trials 2010 2026 2015 2020 1.4k
  1. The status of platinum anticancer drugs in the clinic and in clinical trials (2010)
    Nial Wheate, Shonagh Walker et al. Dalton Transactions
  2. The side effects of platinum-based chemotherapy drugs: a review for chemists (2018)
    Rabbab Oun, Yvonne E. Moussa et al. Dalton Transactions

Citation Impact

Citing Papers

Host–guest complexations of local anaesthetics by cucurbit[7]uril in aqueous solution
2009
Self-assembly of metal–organic polyhedra into supramolecular polymers with intrinsic microporosity
2018 StandoutNobel
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
Synthesis, spectral investigation and biological interphase of drug‐based cytotoxic square pyramidal coordination compounds
2012
Synthesis, characterization, activities, cell uptake and DNA binding of trinuclear complex: [{trans-PtCl(NH3)}2μ-{trans-Pt(NH3)(2-hydroxypyridine)-(H2N(CH2)6NH2)2]Cl4
2005
Anticancer activity of opened arene ruthenium metalla-assemblies
2010
Monolayer coated gold nanoparticles for delivery applications
2011
Hexanuclear self-assembled arene-ruthenium nano-prismatic cages: potential anticancer agents
2011
Monofunctionalized Pillar[5]arene as a Host for Alkanediamines
2011 StandoutNobel
Supramolecular gold nanoparticle–polymer composites formed in water with cucurbit[8]uril
2010
Inclusion complex formation of sanguinarinealkaloid with cucurbit[7]uril: inhibition of nucleophilic attack and photooxidation
2010
Near‐Infrared Light‐Mediated Photoactivation of a Platinum Antitumor Prodrug and Simultaneous Cellular Apoptosis Imaging by Upconversion‐Luminescent Nanoparticles
2013
Inclusion complexes of coumarin in cucurbiturils
2009
Quantitative Emergence of Hetero[4]rotaxanes by Template‐Directed Click Chemistry
2012 StandoutNobel
Toxicology and Drug Delivery by Cucurbit[n]uril Type Molecular Containers
2010
Nanocaged platforms: modification, drug delivery and nanotoxicity. Opening synthetic cages to release the tiger
2016
Cucurbit[8]uril-stabilized charge transfer complexes with diquat driven by pH: a SERS study
2012
Targeting and delivery of platinum-based anticancer drugs
2012
Strong Binding of Hydrocarbons to Cucurbituril Probed by Fluorescent Dye Displacement: A Supramolecular Gas‐Sensing Ensemble
2011
Cucurbit[8]uril/Cucurbit[7]uril Controlled Off/On Fluorescence of the Acridizinium and 9‐Aminoacridizinium Cations in Aqueous Solution
2007
Pt(ii) squares as selective and effective human telomeric G-quadruplex binders and potential cancer therapeutics
2012
Metal N-heterocyclic carbene complexes as potential antitumor metallodrugs
2012
Advances in metal–carbene complexes as potent anti-cancer agents
2011
Crystal structures of Λ-[Ru(phen)2dppz]2+ with oligonucleotides containing TA/TA and AT/AT steps show two intercalation modes
2012
Novel molecular drug carrier: encapsulation of oxaliplatin in cucurbit[7]uril and its effects on stability and reactivity of the drug
2005
An Electrochemically and Thermally Switchable Donor–Acceptor [c2]Daisy Chain Rotaxane
2014 StandoutNobel
The golden age: gold nanoparticles for biomedicine
2011 Standout
Self assembled materials: design strategies and drug delivery perspectives
2013
Dynamic SERS Imaging of Cellular Transport Pathways with Endocytosed Gold Nanoparticles
2011
NIR light controlled photorelease of siRNA and its targeted intracellular delivery based on upconversion nanoparticles
2012
Beating cancer in multiple ways using nanogold
2011
Drug delivery of lipophilic pyrenyl derivatives by encapsulation in a water soluble metalla-cage
2010
Cucurbit[7]uril Pseudorotaxane‐Based Photoresponsive Supramolecular Nanovalve
2012
The Cucurbit[n]uril Family
2005 Standout
Cucurbit[6]urilp-xylylenediammonium diiodide decahydrate inclusion complex
2008
Metal-NHC complexes: a survey of anti-cancer properties
2009
Functionalized cucurbiturils and their applications
2006
Multifunctional Carbon Nanohorn Complexes for Cancer Treatment
2014
Toxicity of cucurbit[7]uril and cucurbit[8]uril: an exploratory in vitro and in vivo study
2010
Biological and cytoselective anticancer properties of copper(II)-polypyridyl complexes modulated by auxiliary methylated glycine ligand
2012
Binding Studies on CB[6] with a Series of 1‐Alkyl‐3‐methylimidazolium Ionic Liquids in an Aqueous System
2010
Direct Exfoliation of Graphite to Graphene in Aqueous Media with Diazaperopyrenium Dications
2013 StandoutNobel
Encapsulation of charge-diffuse peralkylated onium cations in the cavity of cucurbit[7]uril
2008
Gold nanoparticle platforms as drug and biomacromolecule delivery systems
2010
Efficient synthesis and biological evaluation of proximicins A, B and C
2012
Gold nanoparticles in biomedical applications: recent advances and perspectives
2011 Standout
Macrocycles as a Tool: A Facile and One‐Pot Synthesis of Silver Nanoparticles Using Cucurbituril Designed for Cancer Therapeutics
2010
Cucurbituril-resisted acylation of the anti-tuberculosis drug isoniazidvia a supramolecular strategy
2010
Supramolecular Tandem Enzyme Assays for Multiparameter Sensor Arrays and Enantiomeric Excess Determination of Amino Acids
2008
Salt-induced guest relocation from a macrocyclic cavity into a biomolecular pocket: interplay between cucurbit[7]uril and albumin
2008
Cucurbit[7]uril⋅Guest Pair with an Attomolar Dissociation Constant
2014
Recognition of amino acids by functionalized calixarenes
2011
Host–Guest Supramolecular Nanosystems for Cancer Diagnostics and Therapeutics
2013
Redox activation of metal-based prodrugs as a strategy for drug delivery
2012
Encapsulation of Pyrene‐Functionalized Poly(benzyl ether) Dendrons into a Water‐Soluble Organometallic Cage
2011
Toxicology of engineered nanomaterials: Focus on biocompatibility, biodistribution and biodegradation
2010
Phenanthriplatin, a monofunctional DNA-binding platinum anticancer drug candidate with unusual potency and cellular activity profile
2012
A Tumor‐Specific Cascade Amplification Drug Release Nanoparticle for Overcoming Multidrug Resistance in Cancers
2017
Synthesis of an Fe(II) dinuclear triple helicate from a novel -bis-(N-pyrazolyl)pyridine ligand, [Fe2L3]4+: solution and solid-state studies
2012
Recognition Properties of Cucurbit[7]uril Self-Assembled Monolayers Studied with Force Spectroscopy
2011
Toward supramolecular polymers incorporating double cavity cucurbituril hosts
2009
Incorporation of an A1/A2-Difunctionalized Pillar[5]arene into a Metal–Organic Framework
2012 StandoutNobel
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
2016 Standout
Visualizing Light-Triggered Release of Molecules Inside Living Cells
2010
Recent Developments in the Chemistry of Deoxyribonucleic Acid (DNA) Intercalators: Principles, Design, Synthesis, Applications and Trends
2009
Photoremovable Protecting Groups in Chemistry and Biology: Reaction Mechanisms and Efficacy
2012 Standout
Sequential inclusion of two berberine cations in cucurbit[8]uril cavity: kinetic and thermodynamic studies
2014
Supramolecular Coordination: Self-Assembly of Finite Two- and Three-Dimensional Ensembles
2011 Standout
Biospectroscopy of Nanodiamond-Induced Alterations in Conformation of Intra- and Extracellular Proteins: A Nanoscale IR Study
2016
Upconversion Nanoparticles: Design, Nanochemistry, and Applications in Theranostics
2014 Standout
Induction of humoral immune response against PfMSP-119 and PvMSP-119 using gold nanoparticles along with alum
2011
Modular Design of Porous Soft Materials via Self-Organization of Metal–Organic Cages
2018 StandoutNobel
Photoexpulsion of Surface-Grafted Ruthenium Complexes and Subsequent Release of Cytotoxic Cargos to Cancer Cells from Mesoporous Silica Nanoparticles
2013 StandoutNobel
Determining Protease Substrate Selectivity and Inhibition by Label-Free Supramolecular Tandem Enzyme Assays
2011
Atomically Precise Colloidal Metal Nanoclusters and Nanoparticles: Fundamentals and Opportunities
2016 Standout
Complexation of Polyoxometalates with Cyclodextrins
2015 StandoutNobel
Bromine and iodine–cucurbit[6]uril complexes: preparation and applications in synthetic organic chemistry
2014
Cucurbituril chemistry: a tale of supramolecular success
2011
Encapsulation of a β-carboline in cucurbit[7]uril
2009
Developmental and organ-specific toxicity of cucurbit[7]uril: in vivo study on zebrafish models
2015
Pillar[5]arene as a Co-Factor in Templating Rotaxane Formation
2013 StandoutNobel
Die Cucurbit[n]uril‐Familie
2005
Ex2Box: Interdependent Modes of Binding in a Two-Nanometer-Long Synthetic Receptor
2013 StandoutNobel
Biological Catalysis Regulated by Cucurbit[7]uril Molecular Containers
2010
Cooperative capture synthesis: yet another playground for copper-free click chemistry
2016 StandoutNobel
Solid-State Supramolecular Assemblies of Tryptophan and Tryptamine with Cucurbit[6]Uril
2011
Black Phosphorus Nanoparticles Potentiate the Anticancer Effect of Oxaliplatin in Ovarian Cancer Cell Line
2017
Cucurbituril-Based Molecular Recognition
2015 Standout
Amphiphilic Molecular Motors for Responsive Aggregation in Water
2015 StandoutNobel
Complexation mechanism of cucurbit[6]uril with hexamethylene diammonium cations in saline solution
2014
Cucurbiturils: from synthesis to high-affinity binding and catalysis
2014
Supramolecular Chirality in Self-Assembled Systems
2015 Standout
Daisy Chain Assembly Formed from a Cucurbit[6]uril Derivative
2012
Chameleonic Binding of the Dimethyldiazaperopyrenium Dication by Cucurbit[8]uril
2013 StandoutNobel
Differentially Addressable Cavities within Metal–Organic Cage-Cross-Linked Polymeric Hydrogels
2015
Surface-Enhanced Raman Spectroscopy for Bioanalysis: Reliability and Challenges
2018 Standout
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Functional Nanomaterials for Phototherapies of Cancer
2014 Standout
Crystal structure and chemical oxidation of the palladium(II) cyclam complex within the cavity of cucurbit[8]uril
2010
Cyclodextrin Capped Gold Nanoparticles as a Delivery Vehicle for a Prodrug of Cisplatin
2013
Supramolecular Analytical Application of Cucurbit[n]urils Using Fluorescence Spectroscopy
2014
Cucurbituril anchored silica gel
2006
Deciphering the host–guest chemistry of Acridine Yellow and Cucurbit[7]uril: An integrated spectroscopic and calorimetric study
2011
Dual-Controlled Nanoparticles Exhibiting AND Logic
2009 StandoutNobel
NIR Photoresponsive Crosslinked Upconverting Nanocarriers Toward Selective Intracellular Drug Release
2013
Recent Developments in the Preparation and Chemistry of Metallacycles and Metallacages via Coordination
2015 Standout
Gold Nanomaterials at Work in Biomedicine
2015
pH Clock-Operated Mechanized Nanoparticles
2009 StandoutNobel
Self Aggregation of Supramolecules of Nitroxides@Cucurbit[8]uril Revealed by EPR Spectra
2009
Stabilization of the (E)-1-Ferrocenyl-2-(1-methyl-4-pyridinium)ethylene Cation by Inclusion in Cucurbit[7]uril
2006
Host–guest complexes of cucurbit[6]uril with isoprenaline: the effect of the metal ion on the crystallization pathway and supramolecular architecture
2013
Cation-Dependent Gold Recovery with α-Cyclodextrin Facilitated by Second-Sphere Coordination
2016 StandoutNobel
Gold Nano-Popcorn-Based Targeted Diagnosis, Nanotherapy Treatment, and In Situ Monitoring of Photothermal Therapy Response of Prostate Cancer Cells Using Surface-Enhanced Raman Spectroscopy
2010
Monofunctionalized Gold Nanoparticles Stabilized by a Single Dendrimer Form Dumbbell Structures upon Homocoupling
2012 StandoutNobel
Supramolecular Inhibition of Amyloid Fibrillation by Cucurbit[7]uril
2014
Probing Cucurbituril Assemblies in Water with TEMPO-like Nitroxides: A Trinitroxide Supraradical with Spin−Spin Interactions
2009
Carbon Nanomaterials for Biological Imaging and Nanomedicinal Therapy
2015 Standout
Controlling the Synthesis and Assembly of Silver Nanostructures for Plasmonic Applications
2011 Standout
Stimuli-responsive Pd2L4metallosupramolecular cages: towards targeted cisplatin drug delivery
2011
Upconversion Luminescent Materials: Advances and Applications
2014 Standout
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
A cucurbit[8]uril inclusion complex with 1,7-dimethyl-1,4,7,10-tetraazacyclododecane tetrachloride
2009
Evolution of water structures in metal-organic frameworks for improved atmospheric water harvesting
2021 StandoutScienceNobel
Acyclic Cucurbit[n]uril Congeners Are High Affinity Hosts
2010
Cucurbit[7]urilhost–guest complexes of cholines and phosphonium cholines in aqueous solution
2009
Advances in Copper Complexes as Anticancer Agents
2013 Standout
Fluorescent Dyes and Their Supramolecular Host/Guest Complexes with Macrocycles in Aqueous Solution
2011
Redox Switchable Daisy Chain Rotaxanes Driven by Radical–Radical Interactions
2014 StandoutNobel
Dendrimers Designed for Functions: From Physical, Photophysical, and Supramolecular Properties to Applications in Sensing, Catalysis, Molecular Electronics, Photonics, and Nanomedicine
2010 Standout
Integration of Porous Coordination Polymers and Gold Nanorods into Core–Shell Mesoscopic Composites toward Light-Induced Molecular Release
2013 StandoutNobel
Allosteric Modulation of Substrate Binding within a Tetracationic Molecular Receptor
2015 StandoutNobel
Structural Basis of Type II Topoisomerase Inhibition by the Anticancer Drug Etoposide
2011 StandoutScience
Upconversion Nanomaterials: Synthesis, Mechanism, and Applications in Sensing
2012
Metal–Organic Frameworks and Self-Assembled Supramolecular Coordination Complexes: Comparing and Contrasting the Design, Synthesis, and Functionality of Metal–Organic Materials
2012 Standout
Emerging Droplet Microfluidics
2017 Standout
Photoswitchable Intramolecular Through-Space Magnetic Interaction
2011 StandoutNobel
Spin Exchange Monitoring of the Strong Positive Homotropic Allosteric Binding of a Tetraradical by a Synthetic Receptor in Water
2014
Redox Control of the Binding Modes of an Organic Receptor
2015 StandoutNobel
Atomically Precise Clusters of Noble Metals: Emerging Link between Atoms and Nanoparticles
2017 Standout

Works of Nial Wheate being referenced

Cucurbit[n]uril: A New Molecule in Host–Guest Chemistry
2006
The Potential of Cucurbit[n]urils in Drug Delivery
2011
The effect of ancillary ligand chirality and phenanthroline functional group substitution on the cytotoxicity of platinum(II)-based metallointercalators
2007
Cucurbit[n]uril binding of platinum anticancer complexes
2005
DNA Intercalators in Cancer Therapy: Organic and Inorganic Drugs and Their Spectroscopic Tools of Analysis
2007
A chemical preformulation study of a host–guest complex of cucurbit[7]uril and a multinuclear platinum agent for enhanced anticancer drug delivery
2009
Evaluation of anionic half generation 3.5–6.5 poly(amidoamine) dendrimers as delivery vehicles for the active component of the anticancer drug cisplatin
2011
Side-on binding of p-sulphonatocalix[4]arene to the dinuclear platinum complex trans-[{PtCl(NH3)2}2μ-dpzm]2+ and its implications for anticancer drug delivery
2008
Multi-Nuclear Platinum Drugs: A New Paradigm in Chemotherapy
2005
Encapsulation of platinum(II)-based DNA intercalators within cucurbit[6,7,8]urils
2007
Cucurbit[7]uril encapsulated cisplatin overcomes cisplatin resistance via a pharmacokinetic effect
2012
Improving platinum(II)-based anticancer drug delivery using cucurbit[n]urils
2008
Solid state stabilisation of the orally delivered drugs atenolol, glibenclamide, memantine and paracetamol through their complexation with cucurbit[7]uril
2010
A 1H NMR study of the oligonucleotide binding of [(en)Pt(μ-dpzm)2Pt(en)]Cl4
2000
Anionic PAMAM dendrimers as drug delivery vehicles for transition metal-based anticancer drugs
2008
Novel platinum(ii)-based anticancer complexes and molecular hosts as their drug delivery vehicles
2007
Multi-nuclear platinum complexes encapsulated in cucurbit[n]uril as an approach to reduce toxicity in cancer treatment
2004
The status of platinum anticancer drugs in the clinic and in clinical trials
2010 Standout
The Host-Guest Chemistry of Proflavine with Cucurbit[6,7,8]urils
2007
Degradation of Bidentate-Coordinated Platinum(II)-Based DNA Intercalators by Reduced l-Glutathione
2008
Rationalising sequence selection by ligand assemblies in the DNA minor groove: the case for thiazotropsin A
2011
Diffusion Coefficient of Cucurbit[n]urils (n = 6 or 7) at Various Concentrations, Temperatures, and pH
2008
Thermal Rearrangement of N -Substituted Pyrazoles to 4,4'-Dipyrazolylmethane and 1,1,2-(4,4',4''-Tripyrazolyl)ethane
2001
Synthesis, Processing and Solid State Excipient Interactions of Cucurbit[6]uril and Its Formulation into Tablets for Oral Drug Delivery
2010
Substituted β-Cyclodextrin and Calix[4]arene As Encapsulatory Vehicles for Platinum(II)-Based DNA Intercalators
2008
Gold Nanoparticles for the Improved Anticancer Drug Delivery of the Active Component of Oxaliplatin
2010
Multi-nuclear platinum complexes as anti-cancer drugs
2003
Cisplatin-Tethered Gold Nanoparticles That Exhibit Enhanced Reproducibility, Drug Loading, and Stability: a Step Closer to Pharmaceutical Approval?
2012
The ex vivo neurotoxic, myotoxic and cardiotoxic activity of cucurbituril-based macrocyclic drug delivery vehicles
2014
Examination of Cucurbit[7]uril and Its Host−Guest Complexes by Diffusion Nuclear Magnetic Resonance
2008
Studies of the Mechanism of Action of Platinum(II) Complexes with Potent Cytotoxicity in Human Cancer Cells
2009
Cisplatin drug delivery using gold-coated iron oxide nanoparticles for enhanced tumour targeting with external magnetic fields
2012
Host–guest complexes of the antituberculosis drugs pyrazinamide and isoniazid with cucurbit[7]uril
2010
Rankless by CCL
2026