Citation Impact
Citing Papers
Rational design and characterization of a Rac GTPase-specific small molecule inhibitor
2004
Immune Control of Tuberculosis by IFN-γ-Inducible LRG-47
2003 StandoutScience
Comprehensive molecular portraits of human breast tumours
2012 StandoutNature
Hrs, a FYVE finger protein localized to early endosomes, is implicated in vesicular traffic and required for ventral folding morphogenesis
1999
Differential Membrane Localization of ERas and Rheb, Two Ras-related Proteins Involved in the Phosphatidylinositol 3-Kinase/mTOR Pathway
2005 StandoutNobel
The pleckstrin homology domain: An intriguing multifunctional protein module
1996
Activation of Store-Operated Ca2+ Current in Xenopus Oocytes Requires SNAP-25 but Not a Diffusible Messenger
1999 StandoutNobel
Molecular Mechanisms Of Tubulogenesis
2002
The GIT Family of ADP-ribosylation Factor GTPase-activating Proteins
2000 StandoutNobel
Rac1 Activity Is Required for the Activation of Hypoxia-inducible Factor 1
2001 StandoutNobel
FYVE finger proteins as effectors of phosphatidylinositol 3-phosphate
1999
Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
2007 StandoutNature
Cloning and characterization of a novel bicoid-related homeobox transcription factor gene, RIEG, involved in Rieger syndrome
1996 Standout
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors
2005
β-Arrestin 1 and Gαq/11 Coordinately Activate RhoA and Stress Fiber Formation following Receptor Stimulation
2004 StandoutNobel
Oncoprotein Networks
1997
Regulated portals of entry into the cell
2003 StandoutNature
The Hallmarks of Cancer
2000 Standout
The G Protein-coupled Receptor CL1 Interacts Directly with Proteins of the Shank Family
2000 StandoutNobel
Identification of a Mouse p21Cdc42/Rac Activated Kinase
1995
The Small GTPase Rho: Cellular Functions and Signal Transduction
1996
Analysis of the Catalytic Domain of Phosphatidylinositol 4-Kinase Type II
2002 StandoutNobel
Lfc and Lsc Oncoproteins Represent Two New Guanine Nucleotide Exchange Factors for the Rho GTP-binding Protein
1996
Rho GTPases in cell biology
2002 StandoutNature
The Dbl family of oncogenes
1996
Direct Interaction of the Rho GDP Dissociation Inhibitor with Ezrin/Radixin/Moesin Initiates the Activation of the Rho Small G Protein
1997
Lymphocyte signalling: A coordinating role for Vav?
1998
Identification of a Novel Guanine Nucleotide Exchange Factor for the Rho GTPase
1996
A role of PIEZO1 in iron metabolism in mice and humans
2021 StandoutNobel
Rho GTPases and signaling networks
1997 Standout
Nrk, an X-linked Protein Kinase in the Germinal Center Kinase Family, Is Required for Placental Development and Fetoplacental Induction of Labor
2011 StandoutNobel
Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family
1997 Standout
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
1999 StandoutNature
Association of Frabin with the Actin Cytoskeleton Is Essential for Microspike Formation through Activation of Cdc42 Small G Protein
1999
Wiskott-Aldrich Syndrome Protein-Deficient Mice Reveal a Role for WASP in T but Not B Cell Activation
1998
A Novel Regulator of p21-activated Kinases
1998
PAK Kinases Are Directly Coupled to the PIX Family of Nucleotide Exchange Factors
1998
Insulin signalling and the regulation of glucose and lipid metabolism
2001 StandoutNature
Frabin, a Novel FGD1-related Actin Filament-binding Protein Capable of Changing Cell Shape and Activating c-Jun N-terminal Kinase
1998
De novo design of bioactive protein switches
2019 StandoutNatureNobel
A Requirement for the Rho-Family GTP Exchange Factor Vav in Positive and Negative Selection of Thymocytes
1997
Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone
2014 StandoutNature
Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
1997 StandoutNature
Endosomal Localization of the Autoantigen EEA1 Is Mediated by a Zinc-binding FYVE Finger
1996
Rho GTPases
1998
Two actions of frabin: direct activation of Cdc42 and indirect activation of Rac
2000
Phosphatidylinositol(3)-Phosphate Signaling Mediated by Specific Binding to RING FYVE Domains
1998
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Rho family small GTP-binding proteins in growth cone signalling
1997
GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5
2003 StandoutNature
Rho and Rac Take Center Stage
2004 Standout
A novel Cdc42Hs mutant induces cellular transformation
1997
DRhoGEF2 encodes a member of the Dbl family of oncogenes and controls cell shape changes during gastrulation in Drosophila
1998
Guanine nucleotide exchange factors for Rho GTPases: turning on the switch
2002
The basics of epithelial-mesenchymal transition
2009 Standout
CED-1 Is a Transmembrane Receptor that Mediates Cell Corpse Engulfment in C. elegans
2001 StandoutNobel
Points of control in inflammation
2002 StandoutNature
Osteogenesis and Bone-Marrow-Derived Cells
2001
A Putative Src Homology 3 Domain Binding Motif but Not the C-terminal Dystrophin WW Domain Binding Motif Is Required for Dystroglycan Function in Cellular Polarity in Drosophila
2007 StandoutNobel
lin-35 and lin-53, Two Genes that Antagonize a C. elegans Ras Pathway, Encode Proteins Similar to Rb and Its Binding Protein RbAp48
1998 StandoutNobel
The stress-activated protein kinase pathways
1999
Crystal Structure of a Phosphatidylinositol 3-Phosphate-Specific Membrane-Targeting Motif, the FYVE Domain of Vps27p
1999
Phosphoinositide Binding Domains
1999
Specific Role of the Truncated βIV-Spectrin Σ6 in Sodium Channel Clustering at Axon Initial Segments and Nodes of Ranvier
2006 StandoutNobel
Cellular Motility Driven by Assembly and Disassembly of Actin Filaments
2003 Standout
Phosphatidylinositol 3-Phosphate Recognition by the FYVE Domain
1999
Cell Signaling by Receptor Tyrosine Kinases
2000 Standout
The Stress Kinase Mitogen-Activated Protein Kinase Kinase (Mkk)7 Is a Negative Regulator of Antigen Receptor and Growth Factor Receptor–Induced Proliferation in Hematopoietic Cells
2001 StandoutNobel
Small GTP-Binding Proteins
2001 Standout
Synthesis and Function of 3-Phosphorylated Inositol Lipids
2001 Standout
Cortactin Localization to Sites of Actin Assembly in Lamellipodia Requires Interactions with F-Actin and the Arp2/3 Complex
2000
Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function
2009 StandoutNobel
Signaling to Rho GTPases
1999
Rac Downregulates Rho Activity
1999
MSE55, a Cdc42 effector protein, induces long cellular extensions in fibroblasts
1999
Integrin Signaling
1999 StandoutScience
FYVE-finger proteins – effectors of an inositol lipid
1999
Membrane Fusion and Exocytosis
1999 StandoutNobel
Identification of a Novel Cortactin SH3 Domain-Binding Protein and Its Localization to Growth Cones of Cultured Neurons
1998
Rho GTPases and the Actin Cytoskeleton
1998 StandoutScience
Small interfering RNAs as a tool to assign Rho GTPase exchange-factor function in vivo
2002
G PROTEIN–COUPLED RECEPTOR KINASES
1998 StandoutNobel
Regulated Membrane Localization of Tiam1, Mediated by the NH2-terminal Pleckstrin Homology Domain, Is Required for Rac-dependent Membrane Ruffling and C-Jun NH2-terminal Kinase Activation
1997
The GTPase Rho has a critical regulatory role in thymus development
1997
Regulation of the Cytoskeleton and Cell Adhesion by the Rho Family GTPases in Mammalian Cells
1999
Integration of Multiple Signals Through Cooperative Regulation of the N-WASP-Arp2/3 Complex
2000 Science
Regulation of phagocytosis by Rho GTPases
2015
Rho GTPases: molecular switches that control the organization and dynamics of the actin cytoskeleton
2000
Activation of Rac and Cdc42 by Integrins Mediates Cell Spreading
1998
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
The WD40 and FYVE domain containing protein 2 defines a class of early endosomes necessary for endocytosis
2006 StandoutNobel
Two Distinct Vps34 Phosphatidylinositol 3–Kinase Complexes Function in Autophagy and Carboxypeptidase Y Sorting inSaccharomyces cerevisiae
2001 StandoutNobel
Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation
2001 Standout
Signal Transduction and Signal Modulation by Cell Adhesion Receptors: The Role of Integrins, Cadherins, Immunoglobulin-Cell Adhesion Molecules, and Selectins
1998
A novel Sec18p/NSF-dependent complex required for Golgi-to-endosome transport in yeast.
1997
De novo design of protein logic gates
2020 StandoutScienceNobel
Works of N.German Pasteris being referenced
Genomic Organization of the Faciogenital Dysplasia (FGD1; Aarskog Syndrome) Gene
1997
Faciogenital dysplasia protein (FGD1) and Vav, two related proteins required for normal embryonic development, are upstream regulators of Rho GTPases
1996
Isolation and characterization of the faciogenital dysplasia (Aarskog-Scott syndrome) gene: A putative RhoRac guanine nucleotide exchange factor
1994
The Faciogenital Dysplasia Gene Product FGD1 Functions as a Cdc42Hs-specific Guanine-Nucleotide Exchange Factor
1996