Citation Impact
Citing Papers
Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression
2009 Standout
Hippo signaling disruption and Akt stimulation of ovarian follicles for infertility treatment
2013 Standout
The DNA-damage response in human biology and disease
2009 StandoutNature
Gamete segregation in female carriers of Robertsonian translocations
2000
Mosaicism for trisomy 21: A review
2014
An Icelandic example of the impact of population structure on association studies
2004
To err (meiotically) is human: the genesis of human aneuploidy
2001 Standout
A Genetic Screen Identifies PITX1 as a Suppressor of RAS Activity and Tumorigenicity
2005
Hic-5 regulates an epithelial program mediated by PPARγ
2005
The genetics of folate metabolism and maternal risk of birth of a child with Down syndrome and associated congenital heart defects
2015
Non-disjunction of chromosome 18
1998
Noninvasive Imaging beyond the Diffraction Limit of 3D Dynamics in Thickly Fluorescent Specimens
2012 StandoutNobel
Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain
2001 StandoutNature
Recombination at work for meiosis
1998
Most mammalian mRNAs are conserved targets of microRNAs
2008 Standout
Meiotic DNA replication checkpoint control in fission yeast
1999 StandoutNobel
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
2006 StandoutNobel
Reprogramming of Somatic Cells to Pluripotency
2010 StandoutNobel
Lung Cancer
2008 Standout
Elite and stochastic models for induced pluripotent stem cell generation
2009 StandoutNatureNobel
Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
2007 StandoutNobel
DNA repair mechanisms in dividing and non-dividing cells
2013
12 Nondisjunction in the Human Male
1997
Pre-meiotic S phase is linked to reductional chromosome segregation and recombination
2001 StandoutNatureNobel
Five Years of GWAS Discovery
2012 Standout
An atlas of genetic correlations across human diseases and traits
2015 Standout
The Epigenomics of Cancer
2007 Standout
Counting cross-overs: characterizing meiotic recombination in mammals
2000
Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions
2008 StandoutNature
PRDM16 controls a brown fat/skeletal muscle switch
2008 StandoutNature
Principal components analysis corrects for stratification in genome-wide association studies
2006 Standout
KLF4, p21 and context-dependent opposing forces in cancer
2005
The Mammalian Epigenome
2007 Standout
Why do human diversity levels vary at a megabase scale?
2005 StandoutNobel
Cytogenetic analyses of culture failures by comparative genomic hybridisation (CGH)–Re-evaluation of chromosome aberration rates in early spontaneous abortions
2001
p21 in cancer: intricate networks and multiple activities
2009 Standout
Maternal sex chromosome non-disjunction: evidence for X chromosome-specific risk factors
2001
Analysis of Human Accelerated DNA Regions Using Archaic Hominin Genomes
2012 StandoutNobel
Down syndrome: genetic recombination and the origin of the extra chromosome 21
2000
Prevalence and specificity of LKB1 genetic alterations in lung cancers
2007
Initial sequence of the chimpanzee genome and comparison with the human genome
2005 StandoutNature
Cytokine gene polymorphism in human disease: on-line databases
1999
Meiotic chromosomes: it takes two to tango
1997
Krüppel-like Factor 4 Is Acetylated by p300 and Regulates Gene Transcription via Modulation of Histone Acetylation
2007
Generation of germline-competent induced pluripotent stem cells
2007 StandoutNatureNobel
Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network
2008 Standout
Trisomic Pregnancy and Earlier Age at Menopause
2000
Maternal meiosis I non-disjunction of chromosome 15: dependence of the maternal age effect on level of recombination
1998
Elucidating the mechanisms of paternal non-disjunction of chromosome 21 in humans
1998
Bonobos Fall within the Genomic Variation of Chimpanzees
2011 StandoutNobel
DNA replication and damage checkpoints and meiotic cell cycle controls in the fission and budding yeasts
2000 StandoutNobel
Fine-scale recombination patterns differ between chimpanzees and humans
2005 StandoutNobel
Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions
2006
The biology of infertility: research advances and clinical challenges
2008
p63 is a p53 homologue required for limb and epidermal morphogenesis
1999 StandoutNature
Defective meiosis in telomere-silencing mutants of Schizosaccharomyces pombe
1998 Nature
Spontaneous X chromosome MI and MII nondisjunction events in Drosophila melanogaster oocytes have different recombinational histories
1996
The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability
2001 StandoutNobel
Risk factors for trisomy 21: Maternal cigarette smoking and oral contraceptive use in a spopulation-based case-control study
1999
Variance component model to account for sample structure in genome-wide association studies
2010 Standout
From meiosis to postmeiotic events: Homologous recombination is obligatory but flexible
2009
Down's syndrome
2003 Standout
The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene
2005
Functional Demarcation of Active and Silent Chromatin Domains in Human HOX Loci by Noncoding RNAs
2007 Standout
Recurrent miscarriage
2006 Standout
Cohesin Rec8 is required for reductional chromosome segregation at meiosis
1999 StandoutNatureNobel
First-Meiotic-Division Nondisjunction in Human Oocytes
1997
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Abnormal folate metabolism and mutation in the methylenetetrahydrofolate reductase gene may be maternal risk factors for Down syndrome
1999
Where the crossovers are: recombination distributions in mammals
2004
Complete Kinetochore Tracking Reveals Error-Prone Homologous Chromosome Biorientation in Mammalian Oocytes
2011
10 Years ofGenomics,Chromosome 21, and Down Syndrome
1998
Regulation of premeiotic S phase and recombination-related double-strand DNA breaks during meiosis in fission yeast
2001 StandoutNobel
The Human Condition—A Molecular Approach
2014 StandoutNobel
The Polycomb complex PRC2 and its mark in life
2011 StandoutNature
Interleukin-1 polymorphisms associated with increased risk of gastric cancer
2000 StandoutNature
Women with a Reduced Ovarian Complement May Have an Increased Risk for a Child with Down Syndrome
2000
Down Syndrome
2020 Standout
Requirement of the Spindle Checkpoint for Proper Chromosome Segregation in Budding Yeast Meiosis
2000 Science
Apolipoprotein E ϵ4 alleles and meiotic origin of non-disjunction in Down syndrome children and in their corresponding fathers and mothers
1998
The role of Krüppel-like factors in the reprogramming of somatic cells to induced pluripotent stem cells.
2009
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
Population‐based study of congenital heart defects in Down syndrome
1998
Studies of non-disjunction in trisomies 2, 7, 15, and 22: does the parental origin of trisomy influence placental morphology?
1998
Murine embryonic stem cell differentiation is promoted by SOCS-3 and inhibited by the zinc finger transcription factor Klf4
2004
An Evolutionary View of the Mechanism for Immune and Genome Diversity
2012 StandoutNobel
Mammalian Meiotic Recombination Hot Spots
2007
Pluripotency and nuclear reprogramming
2008 StandoutNobel
Evolutionary Comparison of the Mechanism of DNA Cleavage with Respect to Immune Diversity and Genomic Instability
2012 StandoutNobel
Promotion of direct reprogramming by transformation-deficient Myc
2010 StandoutNobel
Histone3 lysine4 trimethylation regulated by the facilitates chromatin transcription complex is critical for DNA cleavage in class switch recombination
2010 StandoutNobel
Ovarian Aging: Mechanisms and Clinical Consequences
2009
Centromere Mapping Functions for Aneuploid Meiotic Products: Analysis of rec8, rec10 and rec11 Mutants of the Fission Yeast Schizosaccharomyces pombe
1999
Frequency of meiotic trisomy depends on involved chromosome and mode of ascertainment
1999
Uncapping and Deregulation of Telomeres Lead to Detrimental Cellular Consequences in Yeast
1999 StandoutNobel
Works of Neil E. Lamb being referenced
Identification of Krüppel-like factor 4 as a potential tumor suppressor gene in colorectal cancer
2004
Association between Maternal Age and Meiotic Recombination for Trisomy 21
2004
Recombination rate and reproductive success in humans
2004
LKB1 mutation in large cell carcinoma of the lung
2006
Susceptible chiasmate configurations of chromosome 21 predispose to non–disjunction in both maternal meiosis I and meiosis II
1996
Effect of meiotic recombination on the production of aneuploid gametes in humans
2005
Risk factors for nondisjunction of trisomy 21
2005
Identification of susceptibility loci contributing to a complex disease using conventional segregation, linkage, and association methods
1995
Characterization of susceptible chiasma configurations that increase the risk for maternal nondisjunction of chromosome 21
1997
Estimating Meiotic Exchange Patterns From Recombination Data: An Application to Humans
1997
Methods for genetic linkage analysis using trisomies.
1995