Citation Impact

Citing Papers

Alteration of enzyme specificity by computational loop remodeling and design
2009 StandoutNobel
Robotics for Automated Crystal Formation and Analysis
2003
Crystal Structure of a Class XIB Phospholipase A2 (PLA2)
2009
Pharmacology of LY315920/S-5920, [[3-(Aminooxoacetyl)-2-ethyl-1-(phenylmethyl)-1 H-indol-4-yl]oxy]acetate, a Potent and Selective Secretory Phospholipase A2Inhibitor: A New Class of Anti-Inflammatory Drugs, SPI
1999
Down-Regulation of Na+/K+ATPase Activity by Human Parvovirus B19 Capsid Protein VP1
2013 Standout
Phospholipase A2 subclasses in acute respiratory distress syndrome
2009
The Functions of Five Distinct Mammalian Phospholipase A2s in Regulating Arachidonic Acid Release
1998
A Reassessment of the Low Molecular Weight Phospholipase A2 Gene Family in Mammals
1997
Reactions in Droplets in Microfluidic Channels
2006 Standout
Phospholipase A2 structure/function, mechanism, and signaling
2008
Group V Phospholipase A2-mediated Oleic Acid Mobilization in Lipopolysaccharide-stimulated P388D1Macrophages
2000
Biaryl diacid inhibitors of human s-PLA2 with anti-inflammatory activity
2000
Increase in phospholipase A 2 activity towards lipopolymer-containing liposomes
1998
Inhibition of the complete set of mammalian secreted phospholipases A2 by indole analogues
2004
Human nonpancreatic secreted phospholipase A2: interfacial parameters, substrate specificities, and competitive inhibitors
1993
Marine natural products
1990 Standout
The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing
1995 StandoutNatureNobel
Group V Phospholipase A2-dependent Induction of Cyclooxygenase-2 in Macrophages
1999
Secreted phospholipase A2 as a new enzymatic trigger mechanism for localised liposomal drug release and absorption in diseased tissue
2002
Flavonoids as Phospholipase A2 Inhibitors: Importance of Their Structure for Selective Inhibition of Group II Phospholipase A2
1997
Group-Specific Assays That Distinguish between the Four Major Types of Mammalian Phospholipase A2
1999
Exogenously Added Human Group X Secreted Phospholipase A2 but Not the Group IB, IIA, and V Enzymes Efficiently Release Arachidonic Acid from Adherent Mammalian Cells
2000
Simplified YM-26734 inhibitors of secreted phospholipase A2 group IIA
2008
Mechanism of Inhibition of Human Nonpancreatic Secreted Phospholipase A2 by the Anti-inflammatory Agent BMS-181162*
1995
Inhibition of secretory phospholipase A. 1-Design, synthesis and structure–activity relationship studies starting from 4-tetradecyloxybenzamidine to obtain specific inhibitors of group II sPLAs
2005
Kinetic analysis of a high molecular weight phospholipase A2 from rat kidney: divalent metal-dependent trapping of enzyme on product-containing vesicles
1992
The Binding Mode of Petrosaspongiolide M to the Human Group IIA Phospholipase A2: Exploring the Role of Covalent and Noncovalent Interactions in the Inhibition Process
2008
Functional Coupling Between Various Phospholipase A2s and Cyclooxygenases in Immediate and Delayed Prostanoid Biosynthetic Pathways
1999
Asymmetric Catalysis by Chiral Hydrogen‐Bond Donors
2006 Standout
High-throughput protein crystallization
2000
D‐Tyrosine as a Chiral Precusor to Potent Inhibitors of Human Nonpancreatic Secretory Phospholipase A2 (IIa) with Antiinflammatory Activity
2003
Mechanism of inhibition of human secretory phospholipase A2 by flavonoids: rationale for lead design
2007
Histidine-aromatic interactions in barnase
1992
Expression and characterization of human group V phospholipase A2
1998
Novel Human Secreted Phospholipase A2 with Homology to the Group III Bee Venom Enzyme
2000
A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain
2011 StandoutNatureNobel
Crystal Structure of Human Group X Secreted Phospholipase A2
2002
Structures of two novel crystal forms of Naja naja naja phospholipase A 2 lacking Ca 2+ reveal trimeric packing 1 1Edited by I. A. Wilson
1998
p38 Mitogen-activated Protein Kinase Phosphorylates Cytosolic Phospholipase A2 (cPLA2) in Thrombin-stimulated Platelets
1996
Structure-based drug screening for G-protein-coupled receptors
2012 StandoutNobel
Suppression of murine endotoxic shock by sPLA2 inhibitor, indoxam, through group IIA sPLA2-independent mechanisms
1999
Aptamers as Tools in Molecular Biology and Immunology
1999
The antibacterial properties of secreted phospholipases A2
2000
Calcium‐independent phospholipase A2 mediates proliferation of human promonocytic U937 cells
2008
Different Functional Aspects of the Group II Subfamily (Types IIA and V) and Type X Secretory Phospholipase A2s in Regulating Arachidonic Acid Release and Prostaglandin Generation
1999
Further insights on the structural aspects of PLA2 inhibition by γ-hydroxybutenolide-containing natural products: a comparative study on petrosaspongiolides M–R
2004
A Novel Prokaryotic Phospholipase A2
2002
The Crystal Structure of Prokaryotic Phospholipase A2
2002
Structure and mechanism of human cytosolic phospholipase A2
2000
The phospholipase A2 superfamily and its group numbering system
2006 Standout
Protein engineering
1992 StandoutNobel
Molecular characterization of a gene encoding the Drosophila melanogaster phospholipase A2
2003
Thielocin B3, a novel antiinflammatory human group II phospholipase A2 specific inhibitor from ascomycetes.
1994
M-Type Phospholipase A 2 Receptor as Target Antigen in Idiopathic Membranous Nephropathy
2009 Standout
Regulation of Prostaglandin E2 Biosynthesis by Inducible Membrane-associated Prostaglandin E2 Synthase That Acts in Concert with Cyclooxygenase-2
2000 Standout
The electrostatic basis for the interfacial binding of secretory phospholipases A2
1994
Roles of Trp31 in High Membrane Binding and Proinflammatory Activity of Human Group V Phospholipase A2
1999
Design of new secreted phospholipase A2 inhibitors based on docking calculations by modifying the pharmacophore segments of the FPL67047XX inhibitor
2010
Mobilization of potent plasma bactericidal activity during systemic bacterial challenge. Role of group IIA phospholipase A2.
1998
Interfacial Kinetic and Binding Properties of the Complete Set of Human and Mouse Groups I, II, V, X, and XII Secreted Phospholipases A2
2002
The three-dimensional structures of two toxins from snake venom throw light on the anticoagulant and neurotoxic sites of phospholipase A2
1998
Interactions with Aromatic Rings in Chemical and Biological Recognition
2003 Standout
Augmented prostaglandin E 2 generation resulting from increased activities of cytosolic and secretory phospholipase A 2 and induction of cyclooxygenase-2 in interleukin-1 β -stimulated rat calvarial cells during the mineralizing phase
2000
Molecular mechanisms of necroptosis: an ordered cellular explosion
2010 Standout
Innate immunity of the newborn: basic mechanisms and clinical correlates
2007 Standout
Fas-induced Arachidonic Acid Release Is Mediated by Ca2+-independent Phospholipase A2 but Not Cytosolic Phospholipase A2, Which Undergoes Proteolytic Inactivation
1998
Regulation of Delayed Prostaglandin Production in Activated P388D1 Macrophages by Group IV Cytosolic and Group V Secretory Phospholipase A2s
1999
CD14-dependent Internalization and Metabolism of Extracellular Phosphatidylinositol by Monocytes
1999
A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation
1995 Standout
Groups IV, V, and X Phospholipases A2s in Human Neutrophils
2002
The expanding superfamily of phospholipase A2 enzymes: classification and characterization
2000 Standout
Liposomal drug delivery systems: From concept to clinical applications
2012 Standout
Structural Elements of Secretory Phospholipases A2 Involved in the Binding to M-type Receptors
1995
Interleukin-1-Induced Prostaglandin E2 Biosynthesis in Human Synovial Cells Involves the Activation of Cytosolic Phospholipase A2 and Cyclooxygenase-2
1994
Phospholipase A2 enzymes
2002
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Hypertonic Induction of Aquaporin-5 Expression through an ERK-dependent Pathway
2000 StandoutNobel
Enantioselective Rh-Catalyzed Hydrogenation of N-Formyl Dehydroamino Esters with Monodentate Phosphoramidite Ligands
2006 StandoutNobel
E-Prostanoid-3 Receptors Mediate the Proinflammatory Actions of Prostaglandin E2 in Acute Cutaneous Inflammation
2004 StandoutNobel
N-Substituted 2-aza-[3]-ferrocenophanes. New synthesis using RuCl2(PPh3)3 catalyzed condensation, structure, and electrochemical behavior
1999
Highly Specific and Broadly Potent Inhibitors of Mammalian Secreted Phospholipases A2
2008
Molecular Recognition of Protein−Ligand Complexes:  Applications to Drug Design
1997 Standout
Distinct Roles in Signal Transduction for Each of the Phospholipase A2 Enzymes Present in P388D1 Macrophages
1996
Drug Discovery and Natural Products: End of an Era or an Endless Frontier?
2009 StandoutScience
Isolation of high-affinity GTP aptamers from partially structured RNA libraries
2002 StandoutNobel
Biochemistry and Physiology of Mammalian Secreted Phospholipases A2
2008
Long-Circulating and Target-Specific Nanoparticles: Theory to Practice
2001 Standout
Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials
2015 Standout
Drug targets in inflammation and immunomodulation
1997
Cyclooxygenases: Structural, Cellular, and Molecular Biology
2000 Standout
Structures of Free and Inhibited Human Secretory Phospholipase A 2 from Inflammatory Exudate
1991 Science
One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA
2021 StandoutNobel
Chemically Induced Dimerization of Human Nonpancreatic Secretory Phospholipase A2 by Bis-indole Derivatives
2008
Crystal structure of phospholipase A2 from Indian cobra reveals a trimeric association.
1993
Proposed three-dimensional structure for the cellular prion protein.
1994 StandoutNobel
Practical Methodologies for the Synthesis of Indoles
2006 Standout
Classical Electrostatics in Biology and Chemistry
1995 StandoutScience
Enhanced hydrolysis of phosphatidylcholine by human group II non-pancreatic secreted phospholipase A2 as a result of interfacial activation by specific anions. Potential role of cholesterol sulphate
1995
Docking and scoring in virtual screening for drug discovery: methods and applications
2004 Standout
Implicit Solvation Models:  Equilibria, Structure, Spectra, and Dynamics
1999 Standout
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
In Vivo Protective Role of Human Group IIA Phospholipase A2 against Experimental Anthrax
2005
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
A Practical, Nenitzescu-Based Synthesis of LY311727, the First Potent and Selective s-PLA2 Inhibitor
1996
The Cation−π Interaction
1997 Standout
Serine 228 is essential for catalytic activities of 85-kDa cytosolic phospholipase A2.
1994
Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology
2001 StandoutScience
Cation-π Interactions in Chemistry and Biology: A New View of Benzene, Phe, Tyr, and Trp
1996 StandoutScience
Hydrogen Autotransfer in the N-Alkylation of Amines and Related Compounds using Alcohols and Amines as Electrophiles
2009 Standout
In Silico-Guided Target Identification of a Scaffold-Focused Library:  1,3,5-Triazepan-2,6-diones as Novel Phospholipase A2 Inhibitors
2006
Prostanoid biosynthesis and mechanisms of action
1992
Cloning and expression of a membrane receptor for secretory phospholipases A2.
1994
Mammalian non-pancreatic phospholipases A2
1993
Diversity of group types, regulation, and function of phospholipase A2.
1994 Standout
Spinal phospholipase A2 in inflammatory hyperalgesia: Role of the small, secretory phospholipase A2
2005
Total chemical synthesis of enzymatically active human type II secretory phospholipase A 2
1997
What Can We Learn from Molecular Recognition in Protein–Ligand Complexes for the Design of New Drugs?
1996
Ischemic Cell Death in Brain Neurons
1999 Standout
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
Molecular Docking and 3D-QSAR CoMFA Studies on Indole Inhibitors of GIIA Secreted Phospholipase A2
2010
Interfacial Enzymology:  The Secreted Phospholipase A2-Paradigm
2001
Mammalian Caspases: Structure, Activation, Substrates, and Functions During Apoptosis
1999 Standout
Fmoc-Based Synthesis of Peptide-αThioesters:  Application to the Total Chemical Synthesis of a Glycoprotein by Native Chemical Ligation
1999 StandoutNobel
Stereoselective synthesis of α,γ -diamino acid esters
1992
A Common Mechanism Underlying Promiscuous Inhibitors from Virtual and High-Throughput Screening
2002
Synthesis of β-Lactams from Fluoroketenes and Imines:  Ab Initio Potential Energy Surfaces in Gas Phase and in Solution
1996
Modeling protein structures: construction and their applications
1993
Interleukin‐1‐Induced Prostaglandin E2 Biosynthesis in Human Synovial Cells Involves the Activation of Cytosolic Phospholipase A2 and Cyclooxygenase‐2
1994
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
Recombinant Production and Properties of Binding of the Full Set of Mouse Secreted Phospholipases A2to the Mouse M-Type Receptor
2007
Thrombin-induced phosphorylation and activation of Ca(2+)-sensitive cytosolic phospholipase A2 in human platelets.
1993
REGULATION AND INHIBITION OF PHOSPHOLIPASE A2
1999
Converting Trypsin to Chymotrypsin: The Role of Surface Loops
1992 Science
Was läßt sich aus der molekularen Erkennung in Protein‐Ligand‐Komplexen für das Design neuer Wirkstoffe lernen?
1996
Neurotoxins Affecting Neuroexocytosis
2000 Standout
Bovine viral diarrhea virus NS3 serine proteinase: polyprotein cleavage sites, cofactor requirements, and molecular model of an enzyme essential for pestivirus replication
1997 StandoutNobel

Works of N.D. Jones being referenced

Structure of recombinant human rheumatoid arthritic synovial fluid phospholipase A2 at 2.2 Å resolution
1991 Nature
Structure-based design of the first potent and selective inhibitor of human non-pancreatic secretory phospholipase A2
1995
The structure of A201A, a novel nucleoside antibiotic.
1985
A novel rearrangement of a 6-fluoropenicillin derivative
1974
APOCALYPSEnow: update on automated protein crystallization using the new ACA vapor diffusion plate
1987
γ-Lactam analogues of carbapenems
1986
The crystal structure of α-keto-1,1'-trimethyleneferrocene
1965
Rankless by CCL
2026