Citation Impact
Citing Papers
Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
2010 StandoutScienceNobel
Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica
2008 StandoutScience
Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels
2006 StandoutNobel
The “Three Italy” of the COVID-19 epidemic and the possible involvement of SARS-CoV-2 in triggering complications other than pneumonia
2020
Autolytic Proteolysis within the Function to Find Domain (FIIND) Is Required for NLRP1 Inflammasome Activity
2012
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Immunotherapy targeting 4-1BB: mechanistic rationale, clinical results, and future strategies
2017
NALPs: a novel protein family involved in inflammation
2003
The Tumor Suppressor PTEN Positively Regulates Macroautophagy by Inhibiting the Phosphatidylinositol 3-Kinase/Protein Kinase B Pathway
2001
Asymmetric Direct Aldol Reaction Assisted by Water and a Proline‐Derived Tetrazole Catalyst
2004 Standout
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
2020 Standout
Gout-associated uric acid crystals activate the NALP3 inflammasome
2006 StandoutNature
NALP3 Forms an IL-1β-Processing Inflammasome with Increased Activity in Muckle-Wells Autoinflammatory Disorder
2004 Standout
β1 integrin antagonism on adherent, differentiated human neuroblastoma cells triggers an apoptotic signaling pathway
2000
Regulation of cell death: the calcium–apoptosis link
2003 Standout
Mitofusin 2 tethers endoplasmic reticulum to mitochondria
2008 StandoutNature
Oncogenic kinase signalling
2001 StandoutNature
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
Rapid apoptosis in the pulmonary vasculature distinguishes non-metastatic from metastatic melanoma cells
2004
Cryopyrin activates the inflammasome in response to toxins and ATP
2006 StandoutNature
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
2012 StandoutNature
Mitochondrial permeability transition in acute neurodegeneration
2002
Activation and regulation of the inflammasomes
2013 Standout
Recognition of microorganisms and activation of the immune response
2007 StandoutNature
Autophagy fights disease through cellular self-digestion
2008 StandoutNature
Cellular and Molecular Pathways of Ischemic Neuronal Death
2002
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
Bcl-2-dependent modulation of Ca2+ homeostasis and store-operated channels in prostate cancer cells
2002
Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins
2002
Nicotine Induces Multi-site Phosphorylation of Bad in Association with Suppression of Apoptosis
2004
Cellular survival: a play in three Akts
1999 Standout
β-Adrenergic Pathway Induces Apoptosis through Calcineurin Activation in Cardiac Myocytes
2000
The Bile Acid Tauroursodeoxycholic Acid Modulates Phosphorylation and Translocation of Bad via Phosphatidylinositol 3-Kinase in Glutamate-Induced Apoptosis of Rat Cortical Neurons
2004
The biochemistry of apoptosis
2000 StandoutNature
Endoplasmic reticulum stress: cell life and death decisions
2005 Standout
BCL-2 family members and the mitochondria in apoptosis
1999 Standout
Delivery technologies for cancer immunotherapy
2019 Standout
PI3K/Akt and apoptosis: size matters
2003
Mitochondrial control of cell death
2000 Standout
FK506 is neuroprotective in a model of antiretroviral toxic neuropathy
2002
Apoptosis-based therapies
2002
The microenvironment of the tumour–host interface
2001 StandoutNature
The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change
2001
From endoplasmic-reticulum stress to the inflammatory response
2008 StandoutNature
Regulation of apoptosis by endoplasmic reticulum pathways
2003
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Autophagy and Cell Death
2007
The Ca2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: significance for the molecular mechanism of Bcl-2 action
2001
Cyclosporin A reduces delayed motor neuron death after spinal cord ischemia in rabbits
2003
Type 3 inositol 1,4,5-trisphosphate receptor modulates cell death
2000
Up-Regulation of Calcineurin Aβ mRNA in the Alzheimer's Disease Brain: Assessment by cDNA Microarray
2001
Dysregulation of apoptosis genes in hematopoietic malignancies
2002
Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities
2008 Standout
CARDINAL, a Novel Caspase Recruitment Domain Protein, Is an Inhibitor of Multiple NF-κB Activation Pathways
2001
Neuroprotection by cyclosporin A following transient brain ischemia correlates with the inhibition of the early efflux of cytochrome C to cytoplasm
2004
The Hallmarks of Aging
2013 Standout
ER Stress Triggers Apoptosis by Activating BH3-Only Protein Bim
2007
Inherent calcineurin inhibitor FKBP38 targets Bcl-2 to mitochondria and inhibits apoptosis
2002
Inflammatory Caspases
2004
CARD-8 Protein, a New CARD Family Member That Regulates Caspase-1 Activation and Apoptosis
2002
Role of YAP/TAZ in mechanotransduction
2011 StandoutNature
Linkage of β1-adrenergic stimulation to apoptotic heart cell death through protein kinase A–independent activation of Ca2+/calmodulin kinase II
2003 StandoutNobel
Inflammasomes in health and disease
2012 StandoutNature
Monogene and Polygene Therapy for the Treatment of Experimental Prostate Cancers by Use of Apoptotic Genes bax and bad Driven by the Prostate-Specific Promoter ARR 2 PB
2002
Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death
2001 StandoutScience
Dual modulation of cell survival and cell death by β 2 -adrenergic signaling in adult mouse cardiac myocytes
2001 StandoutNobel
Bcl-2 on the endoplasmic reticulum: protecting the mitochondria from a distance
2003
The Pathophysiology of Mitochondrial Cell Death
2004 StandoutScience
Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering
2001 StandoutNobel
Type 3 inositol 1,4,5‐trisphosphate receptor modulates cell death
2000
Calcineurin-Mediated BAD Dephosphorylation Activates the Caspase-3 Apoptotic Cascade in Traumatic Spinal Cord Injury
2000
Clinical Characteristics of 58 Children With a Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2
2020 Standout
Phorbol esters promote alpha 1-adrenergic receptor phosphorylation and receptor uncoupling from inositol phospholipid metabolism.
1985 StandoutNobel
A Perspective on Cancer Cell Metastasis
2011 StandoutScience
Regioselective ring cleavage of chiral β-trichloromethyl-β-propiolactone with organoaluminum compounds for the synthesis of optically active intermediates
1998
Myocyte Adrenoceptor Signaling Pathways
2003 StandoutScienceNobel
Bcl-2-mediated alterations in endoplasmic reticulum Ca 2+ analyzed with an improved genetically encoded fluorescent sensor
2004 StandoutNobel
14-3-3 Proteins and Survival Kinases Cooperate to Inactivate BAD by BH3 Domain Phosphorylation
2000
Gain-of-function mutations in the mechanically activated ion channel PIEZO2 cause a subtype of Distal Arthrogryposis
2013 StandoutNobel
Advances in Cancer Immunotherapy in Solid Tumors
2016
The Caenorhabditis elegans mucolipin-like gene cup-5 is essential for viability and regulates lysosomes in multiple cell types
2002 StandoutNobel
Linkage of β1-adrenergic stimulation to apoptotic heart cell death through protein kinase A–independent activation of Ca2+/calmodulin kinase II
2003 StandoutNobel
Piezo1, a mechanically activated ion channel, is required for vascular development in mice
2014 StandoutNobel
Siva-1 binds to and inhibits BCL-XL-mediated protection against UV radiation-induced apoptosis
2002
14-3-3 Proteins: Structure, Function, and Regulation
2000 Standout
Reduced Loading of Intracellular Ca2+ Stores and Downregulation of Capacitative Ca2+Influx in Bcl-2–Overexpressing Cells
2000
Nitric oxide prevents axonal degeneration by inducing HIF-1–dependent expression of erythropoietin
2011 StandoutNobel
Apoptosis in Neural Development and Disease
2000
Asymmetric Enamine Catalysis
2007 StandoutNobel
Scanning the human proteome for calmodulin-binding proteins
2005 StandoutNobel
The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease
2006 StandoutScience
Autophagy in Health and Disease: A Double-Edged Sword
2004 StandoutScience
Works of Nazima Pathan being referenced
Phase Ib Study of Utomilumab (PF-05082566), a 4-1BB/CD137 Agonist, in Combination with Pembrolizumab (MK-3475) in Patients with Advanced Solid Tumors
2017
Myocardial depressant effects of interleukin 6 in meningococcal sepsis are regulated by p38 mitogen-activated protein kinase*
2011
Role of interleukin 6 in myocardial dysfunction of meningococcal septic shock
2004
TUCAN, an Antiapoptotic Caspase-associated Recruitment Domain Family Protein Overexpressed in Cancer
2001
The Tumor Suppressor PTEN Regulates T Cell Survival and Antigen Receptor Signaling by Acting as a Phosphatidylinositol 3-Phosphatase
2000
Phase Ib study of PF-05082566 in combination with pembrolizumab in patients with advanced solid tumors.
2016
Biocatalytic preparation of (R)-(−)-1,1,1-trichloro-2-hydroxy-4-methyl-3-pentene, a synthon for potent agricultural pyrethroids
1991
Ca 2+ -Induced Apoptosis Through Calcineurin Dephosphorylation of BAD
1999 Science