Citation Impact

Citing Papers

Regulation of Hepatic Stellate Cell Differentiation by the Neurotrophin Receptor p75 NTR
2007 Science
Galectin-3 regulates myofibroblast activation and hepatic fibrosis
2006
Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis
2007 Standout
Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation
2013 StandoutScience
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis
2023 StandoutNobel
Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair
2005
Hepatic fibrosis 2006: Report of the third AASLD Single Topic Conference
2006
Flt3 Signaling-Dependent Dendritic Cells Protect against Atherosclerosis
2011 StandoutNobel
Cellular and molecular mechanisms of fibrosis
2007 Standout
Liver fibrosis
2005 Standout
Pregnane X Receptor Activators Inhibit Human Hepatic Stellate Cell Transdifferentiation In Vitro
2006
Inhibition of Apoptosis of Activated Hepatic Stellate Cells by Tissue Inhibitor of Metalloproteinase-1 Is Mediated via Effects on Matrix Metalloproteinase Inhibition
2002
The role and regulation of hepatic stellate cell apoptosis in reversal of liver fibrosis
2005
Antibody-targeted myofibroblast apoptosis reduces fibrosis during sustained liver injury
2008
The role of matrix stiffness in regulating cell behavior†
2008
The Global Impact of Hepatic Fibrosis and End-Stage Liver Disease
2008
Mechanisms of liver fibrosis
2005
Increased Angiogenesis Protects against Adipose Hypoxia and Fibrosis in Metabolic Disease-resistant 11β-Hydroxysteroid Dehydrogenase Type 1 (HSD1)-deficient Mice
2011 StandoutNobel
Antifibrotic Agents for Liver Disease
2005
CD133+ hepatic stellate cells are progenitor cells
2006
Liver fibrosis – from bench to bedside
2003 Standout
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
2013 StandoutNature
TLR4 enhances TGF-β signaling and hepatic fibrosis
2007 Standout
Increased stiffness of the rat liver precedes matrix deposition: implications for fibrosis
2007
Function and Regulation of CREB Family Transcription Factors in the Nervous System
2002 Standout
Resveratrol amplifies profibrogenic effects of free fatty acids on human hepatic stellate cells
2009
The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrence
2015 Standout
Delivery materials for siRNA therapeutics
2013 Standout
The biology and function of fibroblasts in cancer
2016 Standout
Macrophages: Master Regulators of Inflammation and Fibrosis
2010 Standout
Hepatic stellate cells and the reversal of fibrosis
2006
Adipogenic Transcriptional Regulation of Hepatic Stellate Cells
2004
LPS-mediated NFκB activation varies between activated human hepatic stellate cells from different donors
2004
Apoptosis: The nexus of liver injury and fibrosis
2004
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
2014 StandoutNature
Engagement of αvβ3 Integrin Regulates Proliferation and Apoptosis of Hepatic Stellate Cells
2004
Inhibition of inhibitor of κB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis
2005
ADAM metallopeptidase with thrombospondin type 1 motif 2 inactivation reduces the extent and stability of carbon tetrachloride–induced hepatic fibrosis in mice
2007
Anandamide induces necrosis in primary hepatic stellate cells†‡
2005
Matrix metalloproteinases, the pros and cons, in liver fibrosis
2006
Reversal of Fibrosis: No Longer a Pipe Dream?
2006
Nonresolving Inflammation
2010 Standout
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Apoptotic body engulfment by hepatic stellate cells promotes their survival by the JAK/STAT and Akt/NF-κB-dependent pathways
2009
Transcriptional regulation of hepatic stellate cell activation: Figure 1
2002
Molecular and cellular mechanisms of liver fibrosis and its regression
2020
A Role for Serotonin (5-HT) in Hepatic Stellate Cell Function and Liver Fibrosis
2006
Caspase 9–dependent killing of hepatic stellate cells by activated Kupffer cells
2002
Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases
2007 Standout
Mechanisms of endotoxin-induced NO, IL-6, and TNF-α production in activated rat hepatic stellate cells: Role of p38 MAPK
2006
Macrophages in Tissue Repair, Regeneration, and Fibrosis
2016 Standout
The Bone Marrow Functionally Contributes to Liver Fibrosis
2006
Role of endogenous opioids in modulating HSC activity in vitro and liver fibrosis in vivo
2007
Mechanisms of Hepatic Fibrogenesis
2008 Standout
Models of liver fibrosis: exploring the dynamic nature of inflammation and repair in a solid organ
2007
Reversal of Hepatic Fibrosis — Fact or Fantasy?
2006
Sinusoidal remodeling and angiogenesis: A new function for the liver-specific pericyte?
2007
CSF-1R inhibition alters macrophage polarization and blocks glioma progression
2013 Standout
Proteasome inhibition induces hepatic stellate cell apoptosis
2006
Hepatocyte Transplantation Activates Hepatic Stellate Cells With Beneficial Modulation of Cell Engraftment in the Rat *
2005
Systemic sclerosis: a prototypic multisystem fibrotic disorder
2007 Standout
Activated stellate cells express the TRAIL receptor-2/death receptor-5 and undergo TRAIL-mediated apoptosis
2003
Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network
2008 Standout
The Role of Matrix Stiffness in Hepatic Stellate Cell Activation and Liver Fibrosis
2005
Activated hepatic stellate cells overexpress p75NTR after partial hepatectomy and undergo apoptosis on nerve growth factor stimulation
2006
Fibroblast Activation Protein Increases Apoptosis, Cell Adhesion, and Migration by the LX-2 Human Stellate Cell Line *
2005
Mechanisms of fibrosis: therapeutic translation for fibrotic disease
2012 Standout
Hepatic stellate cells do not derive from the neural crest
2005
Generation of a monoclonal human single chain antibody fragment to hepatic stellate cells – a potential mechanism for targeting liver anti-fibrotic therapeutics
2005
The pancreatic stellate cell: a star on the rise in pancreatic diseases
2007
Prominent contribution of portal mesenchymal cells to liver fibrosis in ischemic and obstructive cholestatic injuries
2007
Perspective Article: Tissue repair, contraction, and the myofibroblast
2005
Gliotoxin non‐selectively induces apoptosis in fibrotic and normal livers
2005
IgG4-related disease
2014 Standout
Noninvasive Assessment of Liver Fibrosis and Portal Hypertension With Transient Elastography
2008
Protective and pathogenic functions of macrophage subsets
2011 Standout
Replicative Senescence of Activated Human Hepatic Stellate Cells Is Accompanied by A Pronounced Inflammatory But Less Fibrogenic Phenotype
2003
Nuclear Factor-κB1 (p50) Limits the Inflammatory and Fibrogenic Responses to Chronic Injury
2005
Translating an Understanding of the Pathogenesis of Hepatic Fibrosis to Novel Therapies
2013
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Fibroblasts in cancer
2006 Standout
Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis
2012 Standout
Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair
2005
Trk receptors: mediators of neurotrophin action
2001 StandoutNobel
Searching for common stem cells of the hepatic and hematopoietic systems in the human fetal liver: CD34+ cytokeratin 7/8+ cells express markers for stellate cells
2003
Involvement of integrin-linked kinase in carbon tetrachloride–induced hepatic fibrosis in rats
2006
Resolution of liver cirrhosis using vitamin A–coupled liposomes to deliver siRNA against a collagen-specific chaperone
2008
Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
2009 Standout
Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver
2008 Standout
Stellate cell apoptosis by a soluble mediator from immortalized human hepatocytes
2006
Novel sulfasalazine analogues with enhanced NF-kB inhibitory and apoptosis promoting activity
2005
Mechanisms of Disease: mechanisms of hepatic fibrosis and therapeutic implications
2004
Targeting hepatic stellate cells for cell-specific treatment of liver fibrosis
2002
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
2009 Standout
Elastin accumulation is regulated at the level of degradation by macrophage metalloelastase (MMP-12) during experimental liver fibrosis
2011
Human and Rat Hepatic Stellate Cells Express Neurotrophins and Neurotrophin Receptors
2001
The endocannabinoid 2‐arachidonoyl glycerol induces death of hepatic stellate cells via mitochondrial reactive oxygen species
2007
Growth Inhibition and Apoptosis in Liver Myofibroblasts Promoted by Hepatocyte Growth Factor Leads to Resolution from Liver Cirrhosis
2005
Flying Under the Radar: The Immunobiology of Hepatitis C
2006 StandoutNobel
Pregnenolone-16α-carbonitrile inhibits rodent liver fibrogenesis via PXR (pregnane X receptor)-dependent and PXR-independent mechanisms
2005
Mac the knife? Macrophages– the double-edged sword of hepatic fibrosis
2005
Liver fibrosis
2008
Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis
2015 StandoutNobel
Nerve Growth Factor Signaling, Neuroprotection, and Neural Repair
2001
The extracellular matrix: A dynamic niche in cancer progression
2012 Standout
Tissue Cells Feel and Respond to the Stiffness of Their Substrate
2005 StandoutScience
Inhibition of hepatic fibrogenesis by matrix metalloproteinase‐9 mutants in mice
2006
Trk Receptors: Roles in Neuronal Signal Transduction
2003 Standout
Leptin as a novel profibrogenic cytokine in hepatic stellate cells: mitogenesis and inhibition of apoptosis mediated by extracellular regulated kinase (Erk) and Akt phosphorylation
2004
The selective cyclooxygenase‐2 inhibitor SC‐236 reduces liver fibrosis by mechanisms involving non‐parenchymal cell apoptosis and PPARγ activation
2005
Hepatocellular Carcinoma: Epidemiology and Molecular Carcinogenesis
2007 Standout
Immunological and molecular aspects of liver fibrosis in chronic hepatitis C virus infection.
2005
Reversal of Liver Fibrosis and Cirrhosis — An Emerging Reality
2004
Fibrosis — A Common Pathway to Organ Injury and Failure
2015 Standout
Anti‐adipogenic regulation underlies hepatic stellate cell transdifferentiation
2006
Liver fibrosis
2005
Hepatic fibrosis and cirrhosis: The (myo)fibroblastic cell subpopulations involved
2005
Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer
2011 Standout
Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis
2008 Standout
Establishment of an Immortalized Human Hepatic Stellate Cell Line to Develop Antifibrotic Therapies
2003
Scar-Associated Macrophages Are a Major Source of Hepatic Matrix Metalloproteinase-13 and Facilitate the Resolution of Murine Hepatic Fibrosis
2007
Inflammation and metabolism in tissue repair and regeneration
2017 StandoutScience
Growth Factors, Matrices, and Forces Combine and Control Stem Cells
2009 StandoutScience
Novel Role of IL-13 in Fibrosis Induced by Nonalcoholic Steatohepatitis and Its Amelioration by IL-13R-Directed Cytotoxin in a Rat Model
2008
HEPATIC FIBROSIS: Molecular Mechanisms and Drug Targets
2004
Current status of novel antifibrotic therapies in patients with chronic liver disease
2011
Fast detection of liver fibrosis with collagen-binding single-nanometer iron oxide nanoparticles via T 1 -weighted MRI
2023 StandoutNobel
Integrating mechanisms of pulmonary fibrosis
2011 Standout

Works of Nathan Trim being referenced

Hepatocytes Express Nerve Growth Factor during Liver Injury
2003
Impaired Proteolysis of Collagen I Inhibits Proliferation of Hepatic Stellate Cells
2006
Spontaneous recovery from micronodular cirrhosis: Evidence for incomplete resolution associated with matrix cross-linking☆
2004
Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats
2001
Hepatic Stellate Cells Express the Low Affinity Nerve Growth Factor Receptor p75 and Undergo Apoptosis in Response to Nerve Growth Factor Stimulation
2000
Mutation in collagen‐I that confers resistance to the action of collagenase results in failure of recovery from CCl 4 ‐induced liver fibrosis, persistence of activated hepatic stellate cells, and diminished hepatocyte regeneration
2002
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