Standout Papers
Citation Impact
Citing Papers
Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
2014 StandoutScienceNobel
Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage
2016 StandoutScienceNobel
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
Atomic-Level Characterization of the Structural Dynamics of Proteins
2010 StandoutScienceNobel
GPCR Engineering Yields High-Resolution Structural Insights into β 2 -Adrenergic Receptor Function
2007 StandoutScienceNobel
Structure of the Yeast Mitochondrial Large Ribosomal Subunit
2014 ScienceNobel
De novo design of picomolar SARS-CoV-2 miniprotein inhibitors
2020 StandoutScienceNobel
Arrangement of electron transport chain components in bovine mitochondrial supercomplex I 1 III 2 IV 1
2011
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
2018 StandoutScienceNobel
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
Diffraction-unlimited all-optical imaging and writing with a photochromic GFP
2011 StandoutNatureNobel
Discovery of archaeal fusexins homologous to eukaryotic HAP2/GCS1 gamete fusion proteins
2022 StandoutNobel
Structure of a mammalian ryanodine receptor
2014 StandoutNatureNobel
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
Discoveries in structure and physiology of mechanically activated ion channels
2020 StandoutNatureNobel
Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity
2006 Nature
X-Ray Structure of Acid-Sensing Ion Channel 1–Snake Toxin Complex Reveals Open State of a Na+-Selective Channel
2014 StandoutNobel
Unravelling hepatitis C virus replication from genome to function
2005 StandoutNatureNobel
The crystal structure of a voltage-gated sodium channel
2011 Nature
Structural analysis of an eIF3 subcomplex reveals conserved interactions required for a stable and proper translation pre-initiation complex assembly
2011
New CRISPR–Cas systems from uncultivated microbes
2016 StandoutNatureNobel
Irritant-evoked activation and calcium modulation of the TRPA1 receptor
2020 StandoutNatureNobel
High-resolution structure of the Shigella type-III secretion needle by solid-state NMR and cryo-electron microscopy
2014 StandoutNobel
What recent ribosome structures have revealed about the mechanism of translation
2009 StandoutNatureNobel
Force Field Bias in Protein Folding Simulations
2009
Structure and activity of the Cas3 HD nuclease MJ0384, an effector enzyme of the CRISPR interference
2011
Black mamba venom peptides target acid-sensing ion channels to abolish pain
2012 Nature
Enhanced proofreading governs CRISPR–Cas9 targeting accuracy
2017 StandoutNatureNobel
Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor
2010 StandoutNatureNobel
Evolution of a designed protein assembly encapsulating its own RNA genome
2017 StandoutNatureNobel
A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells
2014 StandoutNobel
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
Structure of the nuclease domain of ribonuclease III from M. tuberculosis at 2.1 Å
2005
Solution structure of a minor and transiently formed state of a T4 lysozyme mutant
2011 StandoutNatureNobel
Structure of mammalian eIF3 in the context of the 43S preinitiation complex
2015 StandoutNatureNobel
A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain
2019 StandoutNobel
The structure and function of G-protein-coupled receptors
2009 StandoutNatureNobel
Structure of the mechanically activated ion channel Piezo1
2017 StandoutNatureNobel
TRPV1 structures in distinct conformations reveal activation mechanisms
2013 StandoutNatureNobel
RNA-guided genetic silencing systems in bacteria and archaea
2012 StandoutNatureNobel
Structure of the TRPV1 ion channel determined by electron cryo-microscopy
2013 StandoutNatureNobel
Structure of a nanobody-stabilized active state of the β2 adrenoceptor
2011 StandoutNatureNobel
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
2016 StandoutNatureNobel
Long-timescale molecular dynamics simulations of protein structure and function
2009
Conformational control of DNA target cleavage by CRISPR–Cas9
2015 StandoutNatureNobel
Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
2021 StandoutNobel
Translational Regulation via L11: Molecular Switches on the Ribosome Turned On and Off by Thiostrepton and Micrococcin
2008
Rapid grid‐based construction of the molecular surface and the use of induced surface charge to calculate reaction field energies: Applications to the molecular systems and geometric objects
2001
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase
2005 StandoutNatureNobel
Structure of a β1-adrenergic G-protein-coupled receptor
2008 StandoutNatureNobel
X-ray structure of a ClC chloride channel at 3.0 Å reveals the molecular basis of anion selectivity
2002 StandoutNatureNobel
X-ray structure of the mammalian GIRK2–βγ G-protein complex
2013 NatureNobel
Open-to-closed transition in apo maltose-binding protein observed by paramagnetic NMR
2007 Nature
A Cas9–guide RNA complex preorganized for target DNA recognition
2015 StandoutScienceNobel
Diffusion of nucleoside triphosphates and role of the entry site to the RNA polymerase II active center
2004 StandoutNobel
Electrostatics and dynamics of proteins
2003
Structural integrity of the PCI domain of eIF3a/TIF32 is required for mRNA recruitment to the 43S pre-initiation complexes
2014
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
UCSF ChimeraX: Meeting modern challenges in visualization and analysis
2017 Standout
Structure-Based Design of Functional Amyloid Materials
2014 StandoutNobel
Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan
2015
In Vivo Encapsulation of Nucleic Acids Using an Engineered Nonviral Protein Capsid
2012
Structural relationship between the putative hair cell mechanotransduction channel TMC1 and TMEM16 proteins
2018
Fast Boundary Element Method for the Linear Poisson−Boltzmann Equation
2002
Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin
2011 StandoutScienceNobel
Quantum Mechanical Continuum Solvation Models
2005 Standout
Structural Basis for Double-Stranded RNA Processing by Dicer
2006 StandoutScienceNobel
Computational design of a pH-sensitive IgG binding protein
2013 StandoutNobel
Structure-based membrane dome mechanism for Piezo mechanosensitivity
2017 Nobel
Solution of the linearized Poisson–Boltzmann equation
2004
Structural basis for reversible photoswitching in Dronpa
2007 StandoutNobel
Structural insights into TRPM8 inhibition and desensitization
2019 StandoutScienceNobel
Nonnatural protein–protein interaction-pair design by key residues grafting
2007
Works of Nathan Baker being referenced
Electrostatic interaction between RNA and protein capsid in cowpea chlorotic mottle virus simulated by a coarse‐grain RNA model and a Monte Carlo approach
2004
PDB2PQR: an automated pipeline for the setup of Poisson-Boltzmann electrostatics calculations
2004 Standout
PDB2PQR: expanding and upgrading automated preparation of biomolecular structures for molecular simulations
2007 Standout
Adaptive multilevel finite element solution of the Poisson-Boltzmann equation I. Algorithms and examples
2000
Web servers and services for electrostatics calculations with APBS and PDB2PQR
2011
Adaptive multilevel finite element solution of the Poisson-Boltzmann equation II. Refinement at solvent-accessible surfaces in biomolecular systems
2000
Polarizable atomic multipole solutes in a Poisson-Boltzmann continuum
2007
Electrostatics of nanosystems: Application to microtubules and the ribosome
2001 Standout
The adaptive multilevel finite element solution of the Poisson-Boltzmann equation on massively parallel computers
2001
Assessing implicit models for nonpolar mean solvation forces: The importance of dispersion and volume terms
2006