Standout Papers
- Phosphatidylinositol 3-Kinase Signaling Inhibits DAF-16 DNA Binding and Function via 14-3-3-dependent and 14-3-3-independent Pathways (2001)
- Potent beta-adrenergic antagonist possessing chemically reactive group (1980)
- DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells (2000)
Citation Impact
Citing Papers
Calorie Restriction Promotes Mammalian Cell Survival by Inducing the SIRT1 Deacetylase
2004 StandoutScience
Long-Lived C. elegans daf-2 Mutants Are Resistant to Bacterial Pathogens
2003 StandoutScienceNobel
Functional specialization of β-arrestin interactions revealed by proteomic analysis
2007 StandoutNobel
In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2
2004 StandoutScience
The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin
2005 StandoutScience
Sirtuins as regulators of metabolism and healthspan
2012 Standout
The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor
2004
Evidence of Increased Glyceraldehyde-3-phosphate Dehydrogenase and Fatty Acid Synthetase Promoter Activities in Transiently Transfected Adipocytes from Genetically Obese Rats
1995
Endogenous human microRNAs that suppress breast cancer metastasis
2008 StandoutNature
Partial cloning of SOX-11 and SOX-12, two new human SOX genes
1993
Foxo Transcription Factors Induce the Atrophy-Related Ubiquitin Ligase Atrogin-1 and Cause Skeletal Muscle Atrophy
2004 Standout
Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway
2001 StandoutNobel
Regulation of hypoxanthine phosphoribosyltransferase, glyceraldehyde‐3‐phosphate dehydrogenase and β‐actin mRNA expression in porcine immune cells and tissues
1998
Embryonic expression of the chicken Sox2, Sox3 and Sox11 genes suggests an interactive role in neuronal development
1995
The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
1997 StandoutNatureNobel
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Autophagy and the Integrated Stress Response
2010 Standout
Functional interaction of β-catenin with the transcription factor LEF-1
1996 StandoutNature
The genetics of ageing
2010 StandoutNature
A signature for the HMG‐1 box DNA‐binding proteins
1993
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
2006 StandoutNobel
A new mathematical model for relative quantification in real-time RT-PCR
2001 Standout
Mutant PIK3CA promotes cell growth and invasion of human cancer cells
2005
A Conformational Change in the Eukaryotic Translation Preinitiation Complex and Release of eIF1 Signal Recognition of the Start Codon
2005
Direct Inhibition of the Longevity-Promoting Factor SKN-1 by Insulin-like Signaling in C. elegans
2008
TheSry-related HMG box-containing geneSox6is expressed in the adult testis and developing nervous system of the mouse
1995
Sirtuins, Aging, and Medicine
2011
The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression
2001
XLS13A and XLS13B: SRY-related genes of Xenopus laevis
1997
Molecular cloning and characterization of a rabbit eIF2C protein
1998
The rde-1 Gene, RNA Interference, and Transposon Silencing in C. elegans
1999 StandoutNobel
The cDNA sequence and chromosomal location of the human SOX2 gene
1994
A soma-to-germline transformation in long-lived Caenorhabditis elegans mutants
2009 StandoutNatureNobel
From Sirtuin Biology to Human Diseases: An Update
2012
Exploiting the PI3K/AKT Pathway for Cancer Drug Discovery
2005 Standout
The mouse Sox5 gene encodes a protein containing the leucine zipper and the Q box
1998
Cloning and characterization ofXenopus laevis xSox7 cDNA
1996
Negative regulation of inflammation by SIRT1
2012
Regulation of insulin action and pancreatic β-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1
2002
Definition of a consensus DNA binding site for SRY
1994
Cloning and characterization of mouse mSox13 cDN
1998
cSox21 exhibits a complex and dynamic pattern of transcription during embryonic development of the chick central nervous system
1997
Ageing and apoptosis
2002
Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
2003 StandoutNatureNobel
Dynamic expression of chicken Sox2 and Sox3 genes in ectoderm induced to form neural tissue
1997
DNA binding and bending properties of the postmeiotically expressed Sry-related protein Sox-5
1994
Natural mRNA is required for directing Met-tRNAf binding to 40S ribosomal subunits in animal cells: involvement of Co-eIF-2A in natural mRNA-directed initiation complex formation
1988
The MDM2 gene amplification database
1998
daf-16 Protects the Nematode Caenorhabditis elegans During Food Deprivation
2006
DAF-12 Regulates a Connected Network of Genes to Ensure Robust Developmental Decisions
2011
Solution Structure of the Sequence-specific HMG Box of the Lymphocyte Transcriptional Activator Sox-4
1995
Cloning and expression of Xenopus laevis xSox12 cDNA
1996
Origin and physiological roles of inflammation
2008 StandoutNature
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ
2004 StandoutNature
C. elegans SIR-2.1 Interacts with 14-3-3 Proteins to Activate DAF-16 and Extend Life Span
2006 Nobel
Removal of phosphorylation sites from the β2-adrenergic receptor delays onset of agonist-promoted desensitization
1988 StandoutNatureNobel
Biochemical Analysis of the eIF2βγ Complex Reveals a Structural Function for eIF2α in Catalyzed Nucleotide Exchange
2001
The Hallmarks of Aging
2013 Standout
Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
2005 StandoutNature
A conserved family of genes related to the testis determining gene,SRY
1992
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Sirtuin Catalysis and Regulation
2012
From head to toes: the multiple facets of Sox proteins
1999 Standout
An SRY Mutation Causing Human Sex Reversal Resolves a General Mechanism of Structure-Specific DNA Recognition: Application to the Four-Way DNA Junction
1995
Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression
2019 StandoutNobel
The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES Cells
2003 StandoutNobel
Autophagy in immunity and inflammation
2011 StandoutNature
Structure of the Mammalian Ribosomal 43S Preinitiation Complex Bound to the Scanning Factor DHX29
2013 StandoutNobel
The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures
1992
Mammalian SIRT1 Represses Forkhead Transcription Factors
2004
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
2010 StandoutNobel
Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays
2000 Standout
The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression
2001
Yeast translation initiation suppressor sui2 encodes the alpha subunit of eukaryotic initiation factor 2 and shares sequence identity with the human alpha subunit.
1989
HIF-1α is required for development of the sympathetic nervous system
2019 StandoutNobel
Expression of Sry, the mouse sex determining gene
1995
HMG-1 as a Late Mediator of Endotoxin Lethality in Mice
1999 StandoutScience
Mutational analysis ofSRY in XY females
1993
The beta-adrenergic receptor: rapid purification and covalent labeling by photoaffinity crosslinking.
1982 StandoutNobel
Sex-reversing mutations affect the architecture of SRY-DNA complexes.
1994
SRY, like HMG1, recognizes sharp angles in DNA.
1992
Direct Interaction of SRY-Related Protein SOX9 and Steroidogenic Factor 1 Regulates Transcription of the Human Anti-Müllerian Hormone Gene
1998
Hepatic Nuclear Factor 3- and Hormone-Regulated Expression of the Phosphoenolpyruvate Carboxykinase and Insulin-Like Growth Factor-Binding Protein 1 Genes
1995
Disruption of spatiotemporal hypoxic signaling causes congenital heart disease in mice
2017
The hLEF/TCF-1 alpha HMG protein contains a context-dependent transcriptional activation domain that induces the TCR alpha enhancer in T cells.
1993
Nuclear localization of the testis determining gene product SRY.
1995
An SRY-related gene expressed during spermatogenesis in the mouse encodes a sequence-specific DNA-binding protein.
1992
14-3-3 Proteins: A Number of Functions for a Numbered Protein
2005
DAF-16 Target Genes That Control C. elegans Life-Span and Metabolism
2003 StandoutScienceNobel
The Genetics of Aging
2001 StandoutNobel
Reconstitution of beta-adrenergic receptors in lipid vesicles: affinity chromatography-purified receptors confer catecholamine responsiveness on a heterologous adenylate cyclase system.
1983 StandoutNobel
Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC −/− Colon Carcinoma
1997 StandoutScience
Pure β-adrenergic receptor: the single polypeptide confers catecholamine responsiveness to adenylate cyclase
1983 StandoutNatureNobel
Common mechanism for oncogenic activation of MLL by forkhead family proteins
2002
14-3-3 Proteins: A Number of Functions for a Numbered Protein
2004
Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin
1986 StandoutNatureNobel
Antibodies to the beta-adrenergic receptor: attenuation of catecholamine-sensitive adenylate cyclase and demonstration of postsynaptic receptor localization in brain.
1983 StandoutNobel
Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth
2014 StandoutNobel
Insulin and Sterol-regulatory Element-binding Protein-1c (SREBP-1C) Regulation of Gene Expression in 3T3-L1 Adipocytes
2002
Purification of the beta-adrenergic receptor. Identification of the hormone binding subunit.
1981 StandoutNobel
Sox-4, an Sry-like HMG box protein, is a transcriptional activator in lymphocytes.
1993
Photoaffinity labeling of the beta-adrenergic receptor with azide derivatives of iodoccyanopindolol.
1982
Molecular mechanisms of receptor desensitization using the β-adrenergic receptor-coupled adenylate cyclase system as a model
1985 StandoutNatureNobel
Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa
2015 StandoutNobel
RIM1α phosphorylation at serine-413 by protein kinase A is not required for presynaptic long-term plasticity or learning
2008 StandoutNobel
Extending Healthy Life Span—From Yeast to Humans
2010 StandoutScience
A male-specific role for SOX9 in vertebrate sex determination
1996
Caenorhabditis elegans microRNAs of the let-7 family act in innate immune response circuits and confer robust developmental timing against pathogen stress
2015 StandoutNobel
Affinity chromatography of human platelet α 2 -adrenergic receptors
1982 StandoutNobel
Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3.
1995
Dynamic FoxO transcription factors
2007
Works of Nargis Nasrin being referenced
Phosphatidylinositol 3-Kinase Signaling Inhibits DAF-16 DNA Binding and Function via 14-3-3-dependent and 14-3-3-independent Pathways
2001 StandoutNobel
A molecular study of EBV DNA and p53 mutations in nasopharyngeal carcinoma of Saudi Arab patients
1994
SIRT4 Regulates Fatty Acid Oxidation and Mitochondrial Gene Expression in Liver and Muscle Cells
2010
DNA-binding properties of the product of the testis-determining gene and a related protein
1991 Nature
Multiple insulin-responsive elements regulate transcription of the GAPDH gene
1992
Identification of a core motif that is recognized by three members of the HMG class of transcriptional regulators: IRE‐ABP, SRY, and TCF‐1α
1992
JNK1 Phosphorylates SIRT1 and Promotes Its Enzymatic Activity
2009
Potent beta-adrenergic antagonist possessing chemically reactive group
1980 StandoutNobel
Protein synthesis in rabbit reticulocytes: Requirements for Met-tRNAf·40S preinitiation complex formation with AUG-codon and physiological mRNAs
1984
DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells
2000 StandoutNobel
Purification and properties of eukaryotic initiation factor 2 and its ancillary protein factor (Co-eIF-2A) from yeast Saccharomyces cerevisiae.
1985
Protein synthesis in rabbit reticulocytes. A study of the roles of Co-eIF-2, Co-eIF-2A80, and GDP in peptide chain initiation.
1985
An insulin response element in the glyceraldehyde-3-phosphate dehydrogenase gene binds a nuclear protein induced by insulin in cultured cells and by nutritional manipulations in vivo.
1990
A comparative study of the characteristics of eIF-2 and eIF-2-ancillary factor activities from yeast Saccharomyces cerevisiae and rabbit reticulocytes.
1985
Insulin stimulates glyceraldehyde-3-phosphate dehydrogenase gene expression through cis-acting DNA sequences.
1988