Citation Impact
Citing Papers
Crystal Structure of Rhodopsin: A G Protein-Coupled Receptor
2000 StandoutScience
Complement Factor H Polymorphism and Age-Related Macular Degeneration
2005 StandoutScience
Complement Factor H Variant Increases the Risk of Age-Related Macular Degeneration
2005 StandoutScience
Complement Factor H Polymorphism in Age-Related Macular Degeneration
2005 StandoutScience
New ABCR mutations and clinical phenotype in Italian patients with Stargardt disease.
2000
Genetics and phenotypes of RPE65 mutations in inherited retinal degeneration.
2000
Multidrug resistance in cancer: role of ATP–dependent transporters
2002 Standout
An integrated map of genetic variation from 1,092 human genomes
2012 StandoutNature
An inventory of the human ABC proteins
1999
Pseudoxanthoma elasticum: Mutations in the MRP6 gene encoding a transmembrane ATP-binding cassette (ABC) transporter
2000
Retinopathy in Mice Induced by Disrupted All-trans-retinal Clearance
2008
Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
2024 Standout
Microarray-based mutation analysis of the ABCA4 (ABCR) gene in autosomal recessive cone–rod dystrophy and retinitis pigmentosa
2004
Genetic variation in thioredoxin interacting protein (TXNIP) is associated with hypertriglyceridaemia and blood pressure in diabetes mellitus
2007
Effect of Gene Therapy on Visual Function in Leber's Congenital Amaurosis
2008 Standout
DNA Is a Target of the Photodynamic Effects Elicited in A2E-Laden RPE by Blue-Light Illumination
2003
Complement, Age-Related Macular Degeneration and a Vision of the Future
2010
The Retinal Pigment Epithelium in Visual Function
2005 Standout
Evaluation of the Best disease gene in patients with age-related macular degeneration and other maculopathies
1999
Cone-Rod Dystrophy Due to Mutations in a Novel Photoreceptor-Specific Homeobox Gene () Essential for Maintenance of the Photoreceptor
1997
(Patho)physiological Significance of the Serum- and Glucocorticoid-Inducible Kinase Isoforms
2006
Classical and new roles of β-arrestins in the regulation of G-PROTEIN-COUPLED receptors
2001 StandoutNobel
Mutations in the VMD2 gene are associated with juvenile-onset vitelliform macular dystrophy (Best disease) and adult vitelliform macular dystrophy but not age-related macular degeneration
2000
Age-Related Macular Degeneration
2008 Standout
Mutations in the transporter ABCA12 are associated with lamellar ichthyosis type 2
2003
Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration
2006
Confronting Complexity: the Interlink of Phototransduction and Retinoid Metabolism in the Vertebrate Retina
2001
Sphingolipids and their metabolism in physiology and disease
2017 Standout
Age-Related Macular Degeneration—a Genome Scan in Extended Families
2003
ABCR, the ATP-binding Cassette Transporter Responsible for Stargardt Macular Dystrophy, Is an Efficient Target of All-trans-retinal-mediated Photooxidative Damage in Vitro
2001
Involvement of All-trans-retinal in Acute Light-induced Retinopathy of Mice
2009
Molecular characterisation of soft tissue tumours: a gene expression study
2002 Standout
Oxidative stress-induced mitochondrial DNA damage in human retinal pigment epithelial cells: a possible mechanism for RPE aging and age-related macular degeneration
2003
Essential role of Elovl4 in very long chain fatty acid synthesis, skin permeability barrier function, and neonatal survival
2007
Further Evidence for an Association of ABCR Alleles with Age-Related Macular Degeneration
2000
Clinical Course and Visual Function in a Family With Mutations in the RPE65 Gene
2002
Understanding the tumor immune microenvironment (TIME) for effective therapy
2018 Standout
Insights into the Function of Rim Protein in Photoreceptors and Etiology of Stargardt's Disease from the Phenotype in abcr Knockout Mice
1999
Identification of the gene responsible for Best macular dystrophy
1998
Identification and Characterization of All-trans-retinol Dehydrogenase from Photoreceptor Outer Segments, the Visual Cycle Enzyme That Reduces All-trans-retinal to All-trans-retinol
2000
A Genomewide Scan for Age-Related Macular Degeneration Provides Evidence for Linkage to Several Chromosomal Regions
2003
Complement activation and choriocapillaris loss in early AMD: Implications for pathophysiology and therapy
2014
Balancing Acts
2004 Standout
Evaluation of the Clinical Age-Related Maculopathy Staging System
2006
Genetic factors of age-related macular degeneration
2004
Lens biology: development and human cataractogenesis
1999
Mechanistic Studies of ABCR, the ABC Transporter in Photoreceptor Outer Segments Responsible for Autosomal Recessive Stargardt Disease
2001
Effects of d-amphetamine and phencyclidine on behavior and extracellular concentrations of neurotensin and dopamine in the ventral striatum and the medial prefrontal cortex of the rat
1995
The Biosynthesis of A2E, a Fluorophore of Aging Retina, Involves the Formation of the Precursor, A2-PE, in the Photoreceptor Outer Segment Membrane
2000
Do age-related macular degeneration and cardiovascular disease share common antecedents?
1999
Update on the molecular genetics of retinitis pigmentosa
2001
Localization of the Functional Domains of Human Tissue Inhibitor of Metalloproteinases-3 and the Effects of a Sorsby's Fundus Dystrophy Mutation
1998
Age-Related Macular Degeneration: Etiology, Pathogenesis, and Therapeutic Strategies
2003
Mutation of a Putative Mitochondrial Iron Transporter Gene (ABC7) in X-Linked Sideroblastic Anemia and Ataxia (XLSA/A)
1999
Heat Shock Protein A12B Protects Vascular Endothelial Cells Against Sepsis-Induced Acute Lung Injury in Mice
2017 Standout
Fluorescent pigments of the retinal pigment epithelium and age-related macular degeneration
2001
Assessment of mutations in the best macular dystrophy (VMD2) gene in patients with adult-onset foveomacular vitelliform dystrophy, age-related maculopathy, and bull's-eye maculopathy
2001
ESDN, a Novel Neuropilin-like Membrane Protein Cloned from Vascular Cells with the Longest Secretory Signal Sequence among Eukaryotes, Is Up-regulated after Vascular Injury
2001 StandoutNobel
Modulation of amphetamine-induced striatal dopamine release by ketamine in humans: implications for schizophrenia
2000 StandoutNobel
Complement: a key system for immune surveillance and homeostasis
2010 Standout
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 Standout
Age-related macular degeneration
2012 Standout
Renewal of photoreceptor outer segments and their phagocytosis by theretinal pigment epithelium
2000
Clan Genomics and the Complex Architecture of Human Disease
2011
Targeting multidrug resistance in cancer
2006 Standout
Regulation of Ferroptotic Cancer Cell Death by GPX4
2014 Standout
Role of Oxidative Modifications in Atherosclerosis
2004 Standout
Genetic influence on early age-related maculopathy
2002
Genetic links between brain development and brain evolution
2005
Four deaths and a funeral: from caspases to alternative mechanisms
2001 Standout
The cornified envelope: a model of cell death in the skin
2005 Standout
Retinitis pigmentosa
2006 Standout
A novel mutation in the ABCR gene in four patients with autosomal recessive Stargardt disease
1999
Age-related macular degeneration
2018 Standout
The Human ATP-Binding Cassette (ABC) Transporter Superfamily
2001
Age-Related Macular Degeneration
2006
Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk
2005
Extension of cortical synaptic development distinguishes humans from chimpanzees and macaques
2012 StandoutNobel
Molecular pathology of age-related macular degeneration
2008
The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease
1999
RPE lipofuscin and its role in retinal pathobiology
2005
Thioredoxin-interacting protein links oxidative stress to inflammasome activation
2009 Standout
Current Concepts in the Pathogenesis of Age-Related Macular Degeneration
2004
High-throughput random mutagenesis screen reveals TRPM8 residues specifically required for activation by menthol
2006 StandoutNobel
Age-related Macular Degeneration
2000
CED-1 Is a Transmembrane Receptor that Mediates Cell Corpse Engulfment in C. elegans
2001 StandoutNobel
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Simple and Complex ABCR: Genetic Predisposition to Retinal Disease
2000
Understanding the etiology of Stargardt's disease
2002
Risk factors and biomarkers of age-related macular degeneration
2016
ABC transporters in lipid transport
2000
Vitamin A metabolism in the retinal pigment epithelium: genes, mutations, and diseases
2003
Genetic Risk of Age-related Maculopathy
1998
Functional impairment of lens aquaporin in two families with dominantly inherited cataracts
2000 StandoutNobel
The ABCR Gene in Recessive and Dominant Stargardt Diseases: A Genetic Pathway in Macular Degeneration
1999
Cloning and Characterization of a Human β,β-Carotene-15, 15′-Dioxygenase That Is Highly Expressed in the Retinal Pigment Epithelium
2001
The acute respiratory distress syndrome
2012 Standout
The key roles of elongases and desaturases in mammalian fatty acid metabolism: Insights from transgenic mice
2009
A Pro51Ser mutation in the COCH gene is associated with late onset autosomal dominant progressive sensorineural hearing loss with vestibular defects
1999
Atherosclerosis
2001 Standout
Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans
2009 StandoutNobel
Mutations in the ABC 1 gene in familial HDL deficiency with defective cholesterol efflux
1999
Age-related Macular Degeneration
1998
Biosynthetic Studies of A2E, a Major Fluorophore of Retinal Pigment Epithelial Lipofuscin
2002
Mutations in a novel gene, VMD2, encoding a protein of unknown properties cause juvenile-onset vitelliform macular dystrophy (Best's disease)
1998
Evolution of primate gene expression
2006 StandoutNobel
Dissection of Genomewide-Scan Data in Extended Families Reveals a Major Locus and Oligogenic Susceptibility for Age-Related Macular Degeneration
2004
Retinitis Pigmentosa
1999
Young-onset colorectal cancer
2023
Molecular genetics of macular degeneration
2001
Gene therapy restores vision in a canine model of childhood blindness
2001 Standout
Molecular genetics of human microcephaly
2001
Matrix Metalloproteinases
1999 Standout
Associations of cardiovascular disease and its risk factors with age-related macular degeneration: the POLA study
2001
Future Research Directions in Acute Lung Injury
2003
Macular pigment and risk for age-related macular degeneration in subjects from a Northern European population.
2001
Tumour stem cells and drug resistance
2005 Standout
Impaired fatty acid utilization in thioredoxin binding protein‐2 (TBP‐2)‐deficient mice: a unique animal model of Reye syndrome
2005
Immunotherapy for Colorectal Cancer
2017
ABCR unites what ophthalmologists divide(s)
1998
Immunochemical recognition of A2E, a pigment in the lipofuscin of retinal pigment epithelial cells
2007
Coordinated Transcriptional Regulation of theunc-25Glutamic Acid Decarboxylase and theunc-47GABA Vesicular Transporter by theCaenorhabditis elegansUNC-30 Homeodomain Protein
1999 StandoutNobel
Fluorescence Lifetime Measurements and Biological Imaging
2010 Standout
DAF-16 Target Genes That Control C. elegans Life-Span and Metabolism
2003 StandoutScienceNobel
Diversifying Carotenoid Biosynthetic Pathways by Directed Evolution
2005 StandoutNobel
Light exposure stimulates formation of A2E oxiranes in a mouse model of Stargardt's macular degeneration
2004
Diverse functions of VDUP1 in cell proliferation, differentiation, and diseases.
2007
Functional redundancy of cryptochromes and classical photoreceptors for nonvisual ocular photoreception in mice
2000 StandoutNobel
Activation of Glutamatergic Neurotransmission by Ketamine: A Novel Step in the Pathway from NMDA Receptor Blockade to Dopaminergic and Cognitive Disruptions Associated with the Prefrontal Cortex
1997 Standout
Limited Roles of Rdh8, Rdh12, and Abca4 in all-trans-Retinal Clearance in Mouse Retina
2009
Oxidative Stress: An Essential Factor in the Pathogenesis of Gastrointestinal Mucosal Diseases
2014 Standout
Molecular Genetics of Human Retinal Disease
1999
Regulation and Physiological Roles of Serum- and Glucocorticoid-Induced Protein Kinase Isoforms
2001
Lipopolysaccharide Endotoxins
2002 Standout
Photodamage to human RPE cells by A2-E, a retinoid component of lipofuscin.
2000
Cyclic Nucleotide-Gated Ion Channels
2002
Treatment with isotretinoin inhibits lipofuscin accumulation in a mouse model of recessive Stargardt's macular degeneration
2003
Cloning and characterization of human adenosine 5'-triphosphate-binding cassette, sub-family A, transporter 2 (ABCA2).
2001
The US Twin Study of Age-Related Macular Degeneration
2005
A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration
2007
Biosynthesis of a major lipofuscin fluorophore in mice and humans with ABCR -mediated retinal and macular degeneration
2000
The lipofuscin fluorophore A2E mediates blue light-induced damage to retinal pigmented epithelial cells.
2000
Works of Nanda Singh being referenced
TXNIP gene not associated with familial combined hyperlipidemia in the NHLBI Family Heart Study
2004
Genotype/Phenotype Analysis of a Photoreceptor-Specific ATP-Binding Cassette Transporter Gene, ABCR, in Stargardt Disease
1999
Responses of Limbic and Extrapyramidal Neurotensin Systems to Stimulants of Abuse
1992
Microcephaly with simplified gyral pattern in six related children
1999
Susceptibility Genes in Human Epilepsy
1999
The rod photoreceptor ATP-binding cassette transporter gene, ABCR, and retinal disease: from monogenic to multifactorial
1999
Diverse macular dystrophy phenotype caused by a novel complex mutation in the ELOVL4 gene.
2001
Genotype-phenotype analysis of ABCR variants in macular degeneration probands and siblings.
2002
Cancer Susceptibility Gene Mutations in Individuals With Colorectal Cancer
2017
Mutation of the Stargardt Disease Gene ( ABCR ) in Age-Related Macular Degeneration
1997 Science