Citation Impact
Citing Papers
Programmable RNA recognition using a CRISPR-associated Argonaute
2018 StandoutNobel
Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells
2004
Breaking the Code of DNA Binding Specificity of TAL-Type III Effectors
2009 StandoutScience
A library of siRNA duplexes targeting the phosphoinositide 3-kinase pathway: determinants of gene silencing for use in cell-based screens
2004
Assaying the Drosophila Negative Feedback Loop with RNA Interference in S2 Cells
2005 StandoutNobel
Short-term cytotoxic effects and long-term instability of RNAi delivered using lentiviral vectors
2004
Small RNA: can RNA interference be exploited for therapy?
2003
siRNA binding proteins of microglial cells: PKR is an unanticipated ligand
2005
Treatment Outcome in Endodontics: The Toronto Study. Phases I and II: Orthograde Retreatment
2004
Many commonly used siRNAs risk off-target activity
2004
MicroRNAs
2004 Standout
Human Argonaute2 Mediates RNA Cleavage Targeted by miRNAs and siRNAs
2004 Standout
Coordinated Activities of Human Dicer Domains in Regulatory RNA Processing
2012 StandoutNobel
A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites
2005
Loss of LIN-35, the Caenorhabditis elegansortholog of the tumor suppressor p105Rb, results in enhanced RNA interference
2006 StandoutNobel
Molecular medicine for the brain: silencing of disease genes with RNA interference
2004
Upconverting Nanoparticles
2011 Standout
Small RNAs with Imperfect Match to Endogenous mRNA Repress Translation
2003
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals
2009 StandoutNature
Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting
2011 Standout
Cancer Metastasis: Building a Framework
2006 Standout
Harnessing in vivo siRNA delivery for drug discovery and therapeutic development
2006
Origins and Mechanisms of miRNAs and siRNAs
2009 Standout
Potent effect of target structure on microRNA function
2007 StandoutNobel
Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque
2005
CRISPR–Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV–host factor interactions
2018 StandoutNobel
Delivery materials for siRNA therapeutics
2013 Standout
Noise amidst the silence: off-target effects of siRNAs?
2004
Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation
2010 StandoutNobel
Limitations of previously published systematic reviews evaluating the outcome of endodontic treatment
2009
Short Hairpin Activated Gene Silencing in Mammalian Cells
2004
Functional siRNAs and miRNAs Exhibit Strand Bias
2003 Standout
Modern Endodontic Surgery Concepts and Practice: A Review
2006 Standout
Local RNA Target Structure Influences siRNA Efficacy: Systematic Analysis of Intentionally Designed Binding Regions
2005
Experimental validation of the importance of seed complement frequency to siRNA specificity
2008
Gene Expression Programs in Response to Hypoxia: Cell Type Specificity and Prognostic Significance in Human Cancers
2006
siRNAs: applications in functional genomics and potential as therapeutics
2004
Aptamers as therapeutics
2010 Standout
Biodistribution and function of extracellular miRNA-155 in mice
2015 StandoutNobel
Non-viral vectors for gene-based therapy
2014 Standout
Protein aggregation and neurodegenerative disease
2004 Standout
Sequence-Specific Inhibition of Small RNA Function
2004 StandoutNobel
Approaches for the sequence-specific knockdown of mRNA
2003
Oxygen sensing and hypoxia signalling pathways in animals: the implications of physiology for cancer
2013 StandoutNobel
Treating hepatitis C
2005 StandoutNobel
Genetic regulators of large-scale transcriptional signatures in cancer
2006
Widespread changes in protein synthesis induced by microRNAs
2008 StandoutNature
A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression
2011 StandoutNature
How were new medicines discovered?
2011 Standout
A review of the biomaterials technologies for infection-resistant surfaces
2013 Standout
Silencing Gene Expression with Dicer-Generated siRNA Pools
2005
Efficacy of Bacteriophage Treatment on Pseudomonas aeruginosa Biofilms
2012
Improving the efficiency of RNA interference in mammals
2004
Reflecting on 25 years with MYC
2008 Standout
Comparison of siRNA-induced off-target RNA and protein effects
2007
Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application
2009
A dermal HOX transcriptional program regulates site-specific epidermal fate
2008
Outcome of primary root canal treatment: systematic review of the literature – Part 1. Effects of study characteristics on probability of success
2007 Standout
Comparing effects of mTR and mTERT deletion on gene expression and DNA damage response: a critical examination of telomere length maintenance-independent roles of telomerase
2009 StandoutNobel
Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
2017 StandoutNature
Revealing the world of RNA interference
2004 StandoutNatureNobel
Boosting Bioluminescence Neuroimaging: An Optimized Protocol for Brain Studies
2013
The Hallmarks of Aging
2013 Standout
Inhibition of HIV replication: A powerful antiviral strategy by IFN-β gene delivery in CD4+ cells
2007 StandoutNobel
Gold Nanoparticles for Biology and Medicine
2010 Standout
Endogenous microRNA sponges: evidence and controversy
2016 Standout
Knocking down barriers: advances in siRNA delivery
2009 Standout
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
2010 StandoutNature
A prospective study of the factors affecting outcomes of nonsurgical root canal treatment: part 1: periapical health
2011 Standout
Mechanisms of gene silencing by double-stranded RNA
2004 StandoutNature
SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-κB-Dependent Gene Expression and Organismal Life Span
2009
Control of translation and mRNA degradation by miRNAs and siRNAs: Table 1.
2006 Standout
Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?
2008 Standout
How to use RNA interference
2004
The Success of Endodontic Therapy — Healing and Functionality
2004
Pivoting the Plant Immune System from Dissection to Deployment
2013 StandoutScience
Antitumor Activity of Systemically Delivered Ribozymes Targeting Murine Telomerase RNA
2004 StandoutNobel
Vigilance and Validation: Keys to Success in RNAi Screening
2010
Predicting effective microRNA target sites in mammalian mRNAs
2015 Standout
A syntaxin 10–SNARE complex distinguishes two distinct transport routes from endosomes to the trans-Golgi in human cells
2008
Os8N3 is a host disease-susceptibility gene for bacterial blight of rice
2006
Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome
2004 StandoutNobel
Modulation of Hepatitis C Virus RNA Abundance by a Liver-Specific MicroRNA
2005 StandoutScience
RNA Interference: Biology, Mechanism, and Applications
2003
Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans -Golgi network
2012 StandoutNobel
Works of Nancy Wang being referenced
Genomewide view of gene silencing by small interfering RNAs
2003
Treatment Outcome in Endodontics: The Toronto Study—Phases 3, 4, and 5: Apical Surgery
2009
Biodistribution of Neural Stem Cells After Intravascular Therapy for Hypoxic–Ischemia
2010