Citation Impact
Citing Papers
Activity-Dependent Internalization of Smoothened Mediated by ß-Arrestin 2 and GRK2
2004 StandoutScienceNobel
Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
2013 StandoutScience
Merlin/ NF-2 mediates contact inhibition of growth by suppressing recruitment of Rac to the plasma membrane
2005
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress
2004 Standout
SOX5/6/21 Prevent Oncogene-Driven Transformation of Brain Stem Cells
2017
Notch signalling controls pancreatic cell differentiation
1999 StandoutNatureNobel
Macrophage Regulation of Tumor Responses to Anticancer Therapies
2013
Hallmarks of Cancer: The Next Generation
2011 Standout
Normal variation in fronto-occipital circuitry and cerebellar structure with an autism-associated polymorphism of CNTNAP2
2010
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
2008 StandoutNature
CD44 is required for two consecutive steps in HGF/c-Met signaling
2002
Tumour predisposition in mice heterozygous for a targeted mutation in Nf1
1994
Homozygous Inactivation of theNF1Gene in Bone Marrow Cells from Children with Neurofibromatosis Type 1 and Malignant Myeloid Disorders
1997
Two Cyclin-Dependent Kinase Pathways Are Essential for Polarized Trafficking of Presynaptic Components
2010
Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A
1997 StandoutNatureNobel
Proteins regulating Ras and its relatives
1993 StandoutNature
CD44: From adhesion molecules to signalling regulators
2003 Standout
A novel PKC-regulated mechanism controls CD44–ezrin association and directional cell motility
2002
A subset of p53-deficient embryos exhibit exencephaly
1995
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Disruption of KIF17–Mint1 interaction by CaMKII-dependent phosphorylation: a molecular model of kinesin–cargo release
2007
Wound repair and regeneration
2008 StandoutNature
Intracellular Transport and Kinesin Superfamily Proteins, KIFs: Structure, Function, and Dynamics
2008
JNK mediates pathogenic effects of polyglutamine-expanded androgen receptor on fast axonal transport
2006
ERM proteins and merlin: integrators at the cell cortex
2002 Standout
Cargo selection by specific kinesin light chain 1 isoforms
2006
Microglia and Wnt Pathways: Prospects for Inflammation in Alzheimer’s Disease
2020
Oncoprotein Networks
1997
Mutational and functional analysis of the neurofibromatosis type 1 ( NF1 ) gene
1996
Molecular motors
2003 Nature
Synaptic transmission: A bidirectional and self-modifiable form of cell-cell communication
1993 StandoutNobel
Stability and association of Smoothened, Costal2 and Fused with Cubitus interruptus are regulated by Hedgehog
2003
Vascular system defects and neuronal apoptosis in mice lacking Ras GTPase-activating protein
1995 Nature
S100 protein expression in subpopulations of neurons of rat brain
1995
The Hallmarks of Cancer
2000 Standout
High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice
1998 StandoutNobel
UNC-51/ATG1 kinase regulates axonal transport by mediating motor–cargo assembly
2008
Axonal Transport, Amyloid Precursor Protein, Kinesin-1, and the Processing Apparatus: Revisited
2005
Kinesin superfamily motor proteins and intracellular transport
2009 Standout
Nf1;Trp53 mutant mice develop glioblastoma with evidence of strain-specific effects
2000
Mechanisms of carcinogenesis and the mutant mouse
1996
An immunochemical, ultrastructural, and developmental characterization of the horizontal basal cells of rat olfactory epithelium
1995
Extracellular Matrix Molecules and their Receptors: Functions in Neural Development
1991
Neurexin Iβ and neuroligin are localized on opposite membranes in mature central synapses
2007
ERM proteins and NF2 tumor suppressor: the Yin and Yang of cortical actin organization and cell growth signaling
2002
Advances in the treatment of neurofibromatosis-associated tumours
2013
neurogenin1 Is Essential for the Determination of Neuronal Precursors for Proximal Cranial Sensory Ganglia
1998
The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44
2001
The axonal transport of mitochondria
2012
Electrically driven directional motion of a four-wheeled molecule on a metal surface
2011 StandoutNatureNobel
Polarization-Dependent Selective Transport to the Apical Membrane by KIF5B in MDCK Cells
2007
A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor
1993 Standout
p53 Deficiency Rescues the Adverse Effects of Telomere Loss and Cooperates with Telomere Dysfunction to Accelerate Carcinogenesis
1999 StandoutNobel
Genes and physiology: molecular physiology in genetically engineered animals.
1996
Neuroligins and neurexins link synaptic function to cognitive disease
2008 StandoutNatureNobel
Mechanisms of angiogenesis
1997 StandoutNature
FMRFamide reverses protein phosphorylation produced by 5-HT and cAMP in Aplysia sensory neurons
1989 StandoutNatureNobel
Atherosclerosis — An Inflammatory Disease
1999 Standout
Molecular motors and mechanisms of directional transport in neurons
2005
Genomic Rearrangements and Gene Copy-Number Alterations as a Cause of Nervous System Disorders
2006
Neuronal polarity: from extracellular signals to intracellular mechanisms
2007
Short Dysfunctional Telomeres Impair Tumorigenesis in the INK4aΔ2/3 Cancer-Prone Mouse
1999 StandoutNobel
p21-activated Kinase Links Rac/Cdc42 Signaling to Merlin
2002
An FGF receptor signaling pathway is required for the normal cell migrations of the sex myoblasts in C. elegans hermaphrodites
1995 StandoutNobel
Neurofibromatosis type 1 gene mutations in neuroblastoma
1993
lin-35 and lin-53, Two Genes that Antagonize a C. elegans Ras Pathway, Encode Proteins Similar to Rb and Its Binding Protein RbAp48
1998 StandoutNobel
Human DNA methylomes at base resolution show widespread epigenomic differences
2009 StandoutNature
Mice cloned from olfactory sensory neurons
2004 StandoutNatureNobel
Merlin Phosphorylation by p21-activated Kinase 2 and Effects of Phosphorylation on Merlin Localization
2002
cDNA cloning of the type 1 neurofibromatosis gene: Complete sequence of the NF1 gene product
1991
Site-specific DNA methylation in the neurofibromatosis (NF1) promoter interferes with binding of CREB and SP1 transcription factors
1999
Expression of a β-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice
1998 StandoutNobel
Resolution of Rat Brain Synaptic Phosphoprotein B‐50 into Multiple Forms by Two‐Dimensional Electrophoresis: Evidence for Multisite Phosphorylation
1985
Heparin protects basic and acidic FGF from inactivation
1986
Cooperating oncogenes converge to regulate cyclin/cdk complexes.
1997
Mouse Mutants and Cardiac Development
1996
LSox5 regulates RhoB expression in the neural tube and promotes generation of the neural crest
2004
The Emerging Functions and Mechanisms of Mammalian Fatty Acid–Binding Proteins
2008
β-Arrestin-Dependent Formation of β 2 Adrenergic Receptor-Src Protein Kinase Complexes
1999 StandoutScienceNobel
Genomic circuits and the integrative biology of cardiac diseases
2000 Nature
Altered Functional Connectivity in Frontal Lobe Circuits Is Associated with Variation in the Autism Risk Gene CNTNAP2
2010
Function of Ras as a molecular switch in signal transduction.
1992
Cardiac hypertrophy and sudden death in mice with a genetically clamped renin transgene
2004 StandoutNobel
Structural Characterization and Biological Functions of Fibroblast Growth Factor
1987
EglN3 hydroxylase stabilizes BIM-EL linking VHL type 2C mutations to pheochromocytoma pathogenesis and chemotherapy resistance
2019 StandoutNobel
A General Mechanism for Network-Dosage Compensation in Gene Circuits
2010 StandoutScienceNobel
Regulation of Caenorhabditis elegans neuronal polarity by heterochronic genes
2019 StandoutNobel
Essential role of β-adrenergic receptor kinase 1 in cardiac development and function
1996 StandoutNobel
Integrin Signaling
1999 StandoutScience
Multiple influences of a heparin-binding growth factor on neuronal development.
1987
Contact-dependent inhibition of EGFR signaling by Nf2/Merlin
2007
Vascular Endothelial Growth Factor Is a Secreted Angiogenic Mitogen
1989 StandoutScience
Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology
1988 StandoutScience
Studies and Perspectives of Protein Kinase C
1986 StandoutScience
Angiogenic Factors
1987 StandoutScience
The pathway to signal achievement
1993 Nature
Candidate autism gene screen identifies critical role for cell-adhesion molecule CASPR2 in dendritic arborization and spine development
2012 StandoutNobel
Regulation of development and differentiation by the extracellular matrix
1993
The axonal transport of mitochondria
2005
Biochemical and immunochemical evidence that the "major postsynaptic density protein" is a subunit of a calmodulin-dependent protein kinase.
1983
Wound-Healing Studies in Transgenic and Knockout Mice
2004
Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue
2016 StandoutNobel
A Molecular Elevator
2004 StandoutScienceNobel
Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment
2014 StandoutNobel
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
Operating Molecular Elevators
2006 StandoutNobel
Neural crest cell-cell adhesion controlled by sequential and subpopulationspecific expression of novel cadherins
1995
Atrial-like phenotype is associated with embryonic ventricular failure in retinoid X receptor alpha -/- mice.
1995
Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten
2004 StandoutNobel
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Neuroligin 1 is a postsynaptic cell-adhesion molecule of excitatory synapses
1999 StandoutNobel
Works of Nancy Ratner being referenced
Canonical Wnt/β-catenin Signaling Drives Human Schwann Cell Transformation, Progression, and Tumor Maintenance
2013
Perinatal or Adult Nf1 Inactivation Using Tamoxifen-Inducible PlpCre Each Cause Neurofibroma Formation
2011
Cd44 Enhances Neuregulin Signaling by Schwann Cells
2000
A neuronal cell surface heparan sulfate proteoglycan is required for dorsal root ganglion neuron stimulation of Schwann cell proliferation.
1985
Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis
1992
Isolation of postsynaptic densities retaining their membrane attachment
1983
Mechanisms and Roles of Axon-Schwann Cell Interactions
2004
Plexiform and Dermal Neurofibromas and Pigmentation Are Caused by Nf1 Loss in Desert Hedgehog-Expressing Cells
2008
The protein product of the neurofibromatosis type 1 gene is expressed at highest abundance in neurons, Schwann cells, and oligodendrocytes
1992
A RASopathy gene commonly mutated in cancer: the neurofibromatosis type 1 tumour suppressor
2015
Ruffling membrane, stress fiber, cell spreading and proliferation abnormalities in human Schwannoma cells
1998
P0 is an early marker of the schwann cell lineage in chickens
1991
Preclincial testing of Sorafenib and RAD001 in the Nfflox/flox;DhhCre mouse model of plexiform neurofibroma using magnetic resonance imaging
2011
Myelin glycoprotein P0 is expressed at early stages of chicken and rat embryogenesis
1995
The Nf2 Tumor Suppressor, Merlin, Functions in Rac-Dependent Signaling
2001
What's new in neurofibromatosis? Proceedings from the 2009 NF Conference: New Frontiers
2010
The Nf1 Tumor Suppressor Regulates Mouse Skin Wound Healing, Fibroblast Proliferation, and Collagen Deposited by Fibroblasts
1999
MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors
2012
Neurofibroma-associated macrophages play roles in tumor growth and response to pharmacological inhibition
2012
S100 is present in developing chicken neurons and schwann cell and promotes motor neuron survival in vivo
1992
Neurofibromin, a predominantly neuronal GTPase activating protein in the adult, is ubiquitously expressed during development
1992
Mitogen accumulation in von Recklinghausen neurofibromatosis
1990
Region-specific astrogliosis in brains of mice heterozygous for mutations in the neurofibromatosis type 1 (Nf1) tumor suppressor
1999
Interaction between two isoforms of the NF2 tumor suppressor protein, merlin, and between merlin and ezrin, suggests modulation of ERM proteins by merlin
2000
Update from the 2011 International Schwannomatosis Workshop: From genetics to diagnostic criteria
2013
A Role for Cyclin-Dependent Kinase(s) in the Modulation of Fast Anterograde Axonal Transport: Effects Defined by Olomoucine and the APC Tumor Suppressor Protein
1998
Identification and Topography of Synaptic Phosphoproteins
1982
Cognitive function and academic performance in neurofibrornatosis 1
1997
Structural organization of filamentous proteins in postsynaptic density
1983
Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues.
1994
Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility
2002
Nf1-Deficient Mouse Schwann Cells Are Angiogenic and Invasive and Can Be Induced To Hyperproliferate: Reversion of Some Phenotypes by an Inhibitor of Farnesyl Protein Transferase
1997
Angiogenic and invasive properties of neurofibroma Schwann cells.
1990
Activation of the Tumor Suppressor Merlin Modulates Its Interaction with Lipid Rafts
2004
The neuronal cell-surface molecule mitogenic for Schwann cells is a heparin-binding protein.
1988
Brain Lipid Binding Protein in Axon-Schwann Cell Interactions and Peripheral Nerve Tumorigenesis
2003
Phase II study of erlotinib in metastatic or unresectable malignant peripheral nerve sheath tumors (MPNST)
2006
Schwann cells from neurofibromin deficient mice exhibit activation of p21ras, inhibition of cell proliferation and morphological changes.
1995