Standout Papers
Citation Impact
Citing Papers
Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro
2006 StandoutNobel
HCV Persistence and Immune Evasion in the Absence of Memory T Cell Help
2003 StandoutScienceNobel
Robust hepatitis C virus infection in vitro
2005
Complete Replication of Hepatitis C Virus in Cell Culture
2005 StandoutScienceNobel
Characterization of a canine homolog of hepatitis C virus
2011 StandoutNobel
A drug-controllable tag for visualizing newly synthesized proteins in cells and whole animals
2008 StandoutNobel
Evidence for a functional RNA element in the hepatitis C virus core gene
2007 StandoutNobel
Mouse models of acute and chronic hepacivirus infection
2017 StandoutScienceNobel
Proteomics of HCV virions reveals an essential role for the nucleoporin Nup98 in virus morphogenesis
2016 StandoutNobel
Immunotherapy of chronic hepatitis C virus infection with antibodies against programmed cell death-1 (PD-1)
2013 StandoutNobel
Intracellular Innate Immune Cascades and Interferon Defenses That Control Hepatitis C Virus
2009
Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism
2009 StandoutNobel
To Interfere and to Anti-interfere: The Interplay Between Hepatitis C Virus and Interferon
2002
Hepatitis C virus kinetics during and immediately after liver transplantation
2002
Possible mechanisms of action and reasons for failure of antiviral therapy in chronic hepatitis C
1999
SEC14L2 enables pan-genotype HCV replication in cell culture
2015 StandoutNatureNobel
Kinetics of hepatitis C virus reinfection after liver transplantation
2006
Genetic variation in IL28B and spontaneous clearance of hepatitis C virus
2009 StandoutNature
Hepatitis C Virus Infection
2001 Standout
Completion of the entire hepatitis C virus life cycle in genetically humanized mice
2013 StandoutNatureNobel
Viral genome imaging of hepatitis C virus to probe heterogeneous viral infection and responses to antiviral therapies
2016 StandoutNobel
Immune selection and genetic sequence variation in core and envelope regions of hepatitis C virus
1999
Treatment triumphs
2014 StandoutNatureNobel
Direct Infection and Replication of Naturally Occurring Hepatitis C Virus Genotypes 1, 2, 3 and 4 in Normal Human Hepatocyte Cultures
2008
Unravelling hepatitis C virus replication from genome to function
2005 StandoutNatureNobel
Diagnostic tests for hepatitis C
1999
Pretreatment Intrahepatic CD8+Cell Count Correlates with Virological Response to Antiviral Therapy in Chronic Hepatitis C Virus Infection
2003
The Outcome of Hepatitis C Virus Infection Is Predicted by Escape Mutations in Epitopes Targeted by Cytotoxic T Lymphocytes
2001 StandoutNobel
Global transcriptional response to interferon is a determinant of HCV treatment outcome and is modified by race
2006
Modelling hepatitis C therapy—predicting effects of treatment
2015
Interferon alfa treatment of HCV RNA carriers with persistently normal transaminase levels: A pilot randomized controlled study
1998
Dynamics of Alanine Aminotransferase During Hepatitis C Virus Treatment
2003
Combination of interferon induction therapy and ribavirin in chronic hepatitis C
2001
Viral kinetics and mathematical models
1999
Visualizing Hepatitis C Virus Infections in Human Liver by Two-Photon Microscopy
2009
Replication Vesicles are Load- and Choke-Points in the Hepatitis C Virus Lifecycle
2013
Prospects for a vaccine against the hepatitis C virus
2005 StandoutNatureNobel
Antibody neutralization and escape by HIV-1
2003 StandoutNature
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
2005 StandoutNature
Hepatitis C virus–specific T-cell reactivity during interferon and ribavirin treatment in chronic hepatitis C
2000
Viral Dynamics and Response Differences in Hcv–Infected African American and White Patients Treated With Ifn and Ribavirin
2003
Protease Inhibitor–Resistant Hepatitis C Virus Mutants With Reduced Fitness From Impaired Production of Infectious Virus
2010
The Humoral Immune Response to HCV: Understanding is Key to Vaccine Development
2014
American Gastroenterological Association Technical Review on the Management of Hepatitis C
2006
Update on hepatitis C virus resistance to direct-acting antiviral agents
2014
Stable Cytotoxic T Cell Escape Mutation in Hepatitis C Virus Is Linked to Maintenance of Viral Fitness
2008 StandoutNobel
Focal Distribution of Hepatitis C Virus RNA in Infected Livers
2009
Characterization of host‐range and cell entry properties of the major genotypes and subtypes of hepatitis C virus†
2005
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
Peginterferon Alfa-2a in Patients with Chronic Hepatitis C
2000
Hepatitis C virus mutation affects proteasomal epitope processing
2004
Structural biology of hepatitis C virus
2004
Dynamics of Hepatitis C Virus Replication in Human Liver
2003
Hepatitis C therapeutics: current status and emerging strategies
2002
A genetically humanized mouse model for hepatitis C virus infection
2011 StandoutNatureNobel
Modelling viral and immune system dynamics
2002
Pathogenesis, diagnosis and management of hepatitis C
2000
Second hepatitis C replication compartment indicated by viral dynamics during liver transplantation
2005
Novel Insights into Hepatitis C Virus Replication and Persistence
2004
Mathematical analysis of multiscale models for hepatitis C virus dynamics under therapy with direct-acting antiviral agents
2013
New therapeutic strategies for hepatitis C
2002 StandoutNobel
A Novel Unsupervised Method to Identify Genes Important in the Anti-viral Response: Application to Interferon/Ribavirin in Hepatitis C Patients
2007
Hepatitis C virus kinetics and host responses associated with disease and outcome of infection in chimpanzees
2004 StandoutNobel
Genomic response to interferon-α in chimpanzees: Implications of rapid downregulation for hepatitis C kinetics
2006
25 years of interferon-based treatment of chronic hepatitis C: an epoch coming to an end
2013
Rapid production and clearance of HIV-1 and hepatitis C virus assessed by large volume plasma apheresis
1999
Peginterferon alone or with ribavirin enhances HCV-specific CD4+ T-helper 1 responses in patients with chronic hepatitis C
2002
Mathematical modeling of primary hepatitis C infection: Noncytolytic clearance and early blockage of virion production
2005 StandoutNobel
A Randomized, Double–Blind Trial Comparing Pegylated Interferon Alfa–2B to Interferon Alfa–2B As Initial Treatment for Chronic Hepatitis C
2001
Replication of hepatitis C virus
2007 StandoutNobel
Hepatitis C Virus RNA Functionally Sequesters miR-122
2015 StandoutNobel
Cellular immune selection with hepatitis C virus persistence in humans
2005
Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates
2011 StandoutNobel
Flying Under the Radar: The Immunobiology of Hepatitis C
2006 StandoutNobel
Replication of hepatitis C virus
2000
Combination of a Hepatitis C Virus NS3-NS4A Protease Inhibitor and Alpha Interferon Synergistically Inhibits Viral RNA Replication and Facilitates Viral RNA Clearance in Replicon Cells
2004
Cytopathic and Noncytopathic Interferon Responses in Cells Expressing Hepatitis C Virus Subgenomic Replicons
2003
Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors
2013 StandoutScienceNobel
Ultrastructural analysis of hepatitis C virus particles
2013 StandoutNobel
Peginterferon Alfa-2a plus Ribavirin for Chronic Hepatitis C Virus Infection
2002 Standout
Plasma chemokine levels correlate with the outcome of antiviral therapy in patients with hepatitis C
2005 StandoutNobel
Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus
2012 StandoutNobel
Monoclonal Antibody AP33 Defines a Broadly Neutralizing Epitope on the Hepatitis C Virus E2 Envelope Glycoprotein
2005
Antiapoptotic and Oncogenic Potentials of Hepatitis C Virus Are Linked to Interferon Resistance by Viral Repression of the PKR Protein Kinase
1999
Antiviral Actions of Interferons
2001 Standout
Divergent and convergent evolution after a common-source outbreak of hepatitis C virus
2005
Course and outcome of hepatitis C
2002
Modeling shows that the NS5A inhibitor daclatasvir has two modes of action and yields a shorter estimate of the hepatitis C virus half-life
2013
Genetic diversity and evolution of hepatitis C virus – 15 years on
2004
Modelling how ribavirin improves interferon response rates in hepatitis C virus infection
2004 Nature
Quasispecies Heterogeneity within the E1/E2 Region as a Pretreatment Variable during Pegylated Interferon Therapy of Chronic Hepatitis C Virus Infection
2005
Modulation of Hepatitis C Virus RNA Abundance by a Liver-Specific MicroRNA
2005 StandoutScience
Cellular cofactors affecting hepatitis C virus infection and replication
2007 StandoutNobel
Mathematical Modeling of Subgenomic Hepatitis C Virus Replication in Huh-7 Cells
2006 StandoutNobel
Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs
2002 StandoutNobel
Hepatitis C virus mutation affects proteasomal epitope processing
2004
Conserved C-Terminal Threonine of Hepatitis C Virus NS3 Regulates Autoproteolysis and Prevents Product Inhibition
2003
A cell protection screen reveals potent inhibitors of multiple stages of the hepatitis C virus life cycle
2010 StandoutNobel
Alpha Interferon Induces Distinct Translational Control Programs To Suppress Hepatitis C Virus RNA Replication
2003
Activation of naïve B lymphocytes via CD81, a pathogenetic mechanism for hepatitis C virus-associated B lymphocyte disorders
2005 StandoutNobel
Modeling Subgenomic Hepatitis C Virus RNA Kinetics during Treatment with Alpha Interferon
2009
Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures
2010 StandoutNobel
Mutations in Hepatitis C Virus E2 Located outside the CD81 Binding Sites Lead to Escape from Broadly Neutralizing Antibodies but Compromise Virus Infectivity
2009 StandoutNobel
Viral Kinetics in Hepatitis C
2003
Cell-Mediated Immunity and the Outcome of Hepatitis C Virus Infection
2004
Structural basis of hepatitis C virus neutralization by broadly neutralizing antibody HCV1
2012
Intrahepatic Hepatitis C Virus Replication Correlates with Chronic Hepatitis C Disease Severity In Vivo
2006
Evidence for Protection against Chronic Hepatitis C Virus Infection in Chimpanzees by Immunization with Replicating Recombinant Vaccinia Virus
2008
Phosphorylation of hepatitis C virus nonstructural protein 5A modulates its protein interactions and viral RNA replication
2004 StandoutNobel
Structure of the catalytic domain of the hepatitis C virus NS2-3 protease
2006 StandoutNatureNobel
Analysis of Hepatitis C Viral Kinetics during Administration of Two Nucleotide Analogues: Sofosbuvir (Gs-7977) and Gs-0938
2014
Characterization of Hepatitis C Virus Core-Specific Immune Responses Primed in Rhesus Macaques by a Nonclassical ISCOM Vaccine
2001 StandoutNobel
Works of Nancy P. Lam being referenced
Differences in Viral Dynamics between Genotypes 1 and 2 of Hepatitis C Virus
2000
Clinical and histologic predictors of response to interferon-α in patients with chronic hepatitis C viral infection
1994
Hepatitis C Viral Dynamics in Vivo and the Antiviral Efficacy of Interferon-α Therapy
1998 StandoutScience