Citation Impact
Citing Papers
High Frequency of TP53 Mutation in BRCA1 and Sporadic Basal-like Carcinomas but not in BRCA1 Luminal Breast Tumors
2009
Breast and Ovarian Cancer Risks Due to Inherited Mutations in BRCA1 and BRCA2
2003 StandoutScience
Positional cloning of the wheat vernalization gene VRN1
2003 Standout
PARP inhibitors: Synthetic lethality in the clinic
2017 StandoutScience
Gene expression profiling of breast cell lines identifies potential new basal markers
2005
Olaparib for Metastatic Breast Cancer in Patients with a Germline BRCA Mutation
2017 Standout
Triple negative breast cancer: unmet medical needs
2010
Comprehensive molecular portraits of human breast tumours
2012 StandoutNature
Mesenchyme Forkhead 1 ( FOXC2 ) plays a key role in metastasis and is associated with aggressive basal-like breast cancers
2007
Use of immunohistochemical markers can refine prognosis in triple negative breast cancer
2007
Triple negative tumours: a critical review
2007
DICER1 hotspot mutations in non-epithelial gonadal tumours
2013
Hallmarks of Cancer: The Next Generation
2011 Standout
Triple-Negative Breast Cancer: Clinical Features and Patterns of Recurrence
2007 Standout
Ovarian carcinomas with genetic and epigenetic BRCA1 loss have distinct molecular abnormalities
2008
High‐throughput protein expression analysis using tissue microarray technology of a large well‐characterised series identifies biologically distinct classes of breast cancer confirming recent cDNA expression analyses
2005
EGFR associated expression profiles vary with breast tumor subtype
2007
American Society of Clinical Oncology 2007 Update of Recommendations for the Use of Tumor Markers in Breast Cancer
2007 Standout
The Pathology of Familial Breast Cancer: Predictive Value of Immunohistochemical Markers Estrogen Receptor, Progesterone Receptor, HER-2, and p53 in Patients With Mutations in BRCA1 and BRCA2
2002
Triple-Negative Breast Cancer
2010 Standout
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries
2021 Standout
The DNA-damage response in human biology and disease
2009 StandoutNature
Hallmarks of 'BRCAness' in sporadic cancers
2004
Heterogeneity of the Tumor Vasculature
2010
BRCA1 and BRCA2: 1994 and beyond
2004
Breast cancer stem cells: treatment resistance and therapeutic opportunities
2011
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
2005 StandoutNature
Pancreatic cancer
2004 Standout
Genetic Predisposition Directs Breast Cancer Phenotype by Dictating Progenitor Cell Fate
2011
DICER1 mutations in childhood cystic nephroma and its relationship to DICER1-renal sarcoma
2014
Founder mutations in BRCA1 and BRCA2 genes
2007
Cell-cycle checkpoints and cancer
2004 StandoutNature
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
Evolution of the cancer genome
2012
BRCA1 and BRCA2 Mutation Analysis of 208 Ashkenazi Jewish Women with Ovarian Cancer
2000
Ovarian cancer
2014 Standout
X chromosomal abnormalities in basal-like human breast cancer
2006
Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer
2005 Standout
Ovarian sex cord-stromal tumors, pleuropulmonary blastoma and DICER1 mutations: A report from the International Pleuropulmonary Blastoma Registry
2011
DICER1 Mutations in embryonal rhabdomyosarcomas from children with and without familial PPB‐tumor predisposition syndrome
2011
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
2005 StandoutNature
Mutator pathways unleashed by epigenetic silencing in human cancer
2007
Analysis of Circulating Tumor DNA to Monitor Metastatic Breast Cancer
2013 Standout
Reduced Life- and Healthspan in Mice Carrying a Mono-Allelic BubR1 MVA Mutation
2012
Differential oestrogen receptor binding is associated with clinical outcome in breast cancer
2012 StandoutNature
The cancer connection: BRCA1 and BRCA2 tumor suppression in mice and humans
2002
Pistillody, homeotic transformation of stamens into pistil‐like structures, caused by nuclear–cytoplasm interaction in wheat
2002
Skin Cancers after Organ Transplantation
2003 Standout
Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial
2010 Standout
Hypoxia-inducible factor–dependent breast cancer–mesenchymal stem cell bidirectional signaling promotes metastasis
2012 StandoutNobel
DNA Damage, Aging, and Cancer
2009 Standout
Cyclin E Expression and Prognosis in Breast Cancer Patients: A Meta-Analysis of Published Studies
2006
Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
2007 StandoutNature
DNA adducts, genetic polymorphisms, and K-ras mutation in human pancreatic cancer
2002
Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis
2010
Proliferative markers as prognostic and predictive tools in early breast cancer: where are we now?
2005
MicroRNA biogenesis pathways in cancer
2015 Standout
BRCA1 transcriptionally regulates genes associated with the basal-like phenotype in breast cancer
2009
Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours
2014
Modifiers of risk of hereditary breast and ovarian cancer
2002
Evaluation of Factors Related to Late Recurrence - Later than 10 Years after the Initial Treatment - in Primary Breast Cancer
2013 Standout
Emerging Biological Principles of Metastasis
2017 Standout
On the Use of Familial Aggregation in Population-Based Case Probands for Calculating Penetrance
2002
Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells
2011 Standout
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Gene-Expression Signatures in Breast Cancer
2009
BRCA1 functions as a breast stem cell regulator
2004
Worse Breast Cancer Prognosis of BRCA1/BRCA2 Mutation Carriers: What's the Evidence? A Systematic Review with Meta-Analysis
2015
Disruption of the expected positive correlation between breast tumor size and lymph node status in BRCA1‐related breast carcinoma
2003
Synthetic lethality: the road to novel therapies for breast cancer
2016
Meeting Highlights: International Expert Consensus on the Primary Therapy of Early Breast Cancer 2005
2005
Therapeutic potential of PARP inhibitors for metastatic breast cancer
2011
The basics of epithelial-mesenchymal transition
2009 Standout
Olaparib Maintenance Therapy in Platinum-Sensitive Relapsed Ovarian Cancer
2012 Standout
The role of senescent cells in ageing
2014 StandoutNature
Collaboration of Brca1 and Chk2 in tumorigenesis
2004
let-7 Regulates Self Renewal and Tumorigenicity of Breast Cancer Cells
2007 Standout
Cancer Susceptibility and the Functions of BRCA1 and BRCA2
2002
Increased Expression of VEGF-Receptors (FLT-1, KDR, NRP-1) and Thrombospondin-1 is Associated with Glomeruloid Microvascular Proliferation, an Aggressive Angiogenic Phenotype, in Malignant Melanoma
2003
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from BRCA Mutation Carriers
2009 Standout
A Population-Based, Case-Control Study of Polymorphisms in Carcinogen-Metabolizing Genes, Smoking, and Pancreatic Adenocarcinoma Risk
2002
An Alternative Form of Replication Protein A Expressed in Normal Human Tissues Supports DNA Repair
2009 StandoutNobel
Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
2007 StandoutNature
Race, Breast Cancer Subtypes, and Survival in the Carolina Breast Cancer Study
2006 Standout
TP53 Polymorphism of Exon 4 at Codon 72 in Cutaneous Squamous Cell Carcinoma and Benign Epithelial Lesions of Renal Transplant Recipients and Immunocompetent Individuals: Lack of Correlation with Human Papillomavirus Status11This work was presented in part at the 19th International Papillomavirus Conference in Florianopolis, Brazil, September 1–7, 2001.
2002
p21 Both Attenuates and Drives Senescence and Aging in BubR1 Progeroid Mice
2013
The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
2008 Standout
Cancer of the Ovary
2004 Standout
DICER1: mutations, microRNAs and mechanisms
2014
The lifetime risks of breast cancer in Ashkenazi Jewish carriers of BRCA1 and BRCA2 mutations.
2001
DICER1 Syndrome: A New Cancer Syndrome
2013
Change in the penetrance of founder BRCA1/2 mutations? A retrospective cohort study
2002
The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data
2012 Standout
Prognostic Significance of Basal-Like Phenotype and Fascin Expression in Node-Negative Invasive Breast Carcinomas
2006
Pathologic Complete Response Rates in Young Women With BRCA1-Positive Breast Cancers After Neoadjuvant Chemotherapy
2009
Mechanism of Eukaryotic Homologous Recombination
2008
Neuropilin 1 deficiency on CD4+Foxp3+ regulatory T cells impairs mouse melanoma growth
2012 StandoutNobel
Basal-Like Breast Cancer: A Critical Review
2008
Ovarian cancer risk in Ashkenazi Jewish carriers of BRCA1 and BRCA2 mutations.
2002
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Biallelic DICER1 mutations occur in Wilms tumours
2013
Clinical Characteristics of Individuals With Germline Mutations in BRCA1 and BRCA2: Analysis of 10,000 Individuals
2002
Breast Cancer Risk Following Bilateral Oophorectomy in BRCA1 and BRCA2 Mutation Carriers: An International Case-Control Study
2005 Standout
Fallopian Tube and Primary Peritoneal Carcinomas Associated With BRCA Mutations
2003
Screening for Founder Mutations in BRCA1 and BRCA2 in Unselected Jewish Women
2009
Sensitivity to First-Line Chemotherapy for Metastatic Breast Cancer in BRCA1 and BRCA2 Mutation Carriers
2009
Clinical Characteristics of Individuals With Germline Mutations in BRCA1 and BRCA2: Analysis of 10,000 Individuals
2002
Cancer Genome Landscapes
2013 StandoutScience
Estrogen Receptor Status in BRCA1 - and BRCA2 -Related Breast Cancer
2004
Hypoxia-inducible factor 1-dependent expression of platelet-derived growth factor B promotes lymphatic metastasis of hypoxic breast cancer cells
2012 StandoutNobel
Cancer‐associated somatic DICER1 hotspot mutations cause defective miRNA processing and reverse‐strand expression bias to predominantly mature 3p strands through loss of 5p strand cleavage
2012
Sporadic Epithelial Ovarian Cancer: Clinical Relevance of BRCA1 Inhibition in the DNA Damage and Repair Pathway
2008
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
2004 StandoutNobel
Works of Nancy Hamel being referenced
Biallelic Deleterious BRCA1 Mutations in a Woman with Early-Onset Ovarian Cancer
2012
No association between P53 codon 72 polymorphism and risk of squamous cell carcinoma of the head and neck
2000
Founder mutations in BRCA1/2 are not frequent in Canadian Ashkenazi Jewish men with prostate cancer
2003
Germline DICER1 mutation and associated loss of heterozygosity in a pineoblastoma: Figure 1
2012
The frequent BRCA1 mutation 1135insA has multiple origins: a haplotype study in different populations
2006
Impact of germline BRCA1 mutations and overexpression of p53 on prognosis and response to treatment following breast carcinoma
2003
Extending the phenotypes associated withDICER1mutations
2011
Pathogenicity of the BRCA1 missense variant M1775K is determined by the disruption of the BRCT phosphopeptide-binding pocket: a multi-modal approach
2008
Glomeruloid microvascular proliferation is associated with p53 expression, germline BRCA1 mutations and an adverse outcome following breast cancer
2003
Identification of a novel truncating PALB2mutation and analysis of its contribution to early-onset breast cancer in French-Canadian women
2007
Germline DICER1 mutations and familial cystic nephroma
2010
True
2000
Homozygous BUB1B Mutation and Susceptibility to Gastrointestinal Neoplasia
2010
Prevalence and Penetrance of BRCA1 and BRCA2 Gene Mutations in Unselected Ashkenazi Jewish Women With Breast Cancer
1999
Analysis ofPALB2/FANCN-associated breast cancer families
2007
Nuclear Genes Associated With a Single Brassica CMS Restorer Locws Influence Transcripts of Three Different Mitochondrial Gene Regions
1996
The Prognostic Implication of the Basal-Like (Cyclin Ehigh/p27low/p53+/Glomeruloid-Microvascular-Proliferation+) Phenotype of BRCA1 -Related Breast Cancer
2004
TP53 mutations in breast cancer associated with BRCA1 or BRCA2 germ-line mutations: distinctive spectrum and structural distribution.
2001