Citation Impact
Citing Papers
Antisense transcripts from immunoglobulin heavy-chain locus V(D)J and switch regions
2008
A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression
2005 StandoutNobel
C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion
2014 StandoutNobel
Uracil DNA Glycosylase Activity Is Dispensable for Immunoglobulin Class Switch
2004 StandoutScienceNobel
Activation induced deaminase C-terminal domain links DNA breaks to end protection and repair during class switch recombination
2014
MSH2–MSH6 stimulates DNA polymerase η, suggesting a role for A:T mutations in antibody genes
2005
AID from bony fish catalyzes class switch recombination
2005
Cutting Edge: CTNNBL1 Is Dispensable for Ig Class Switch Recombination
2010
Classical and Alternative End-Joining Pathways for Repair of Lymphocyte-Specific and General DNA Double-Strand Breaks
2012
Discovery of Activation‐Induced Cytidine Deaminase, the Engraver of Antibody Memory
2007 StandoutNobel
Evolution of the Immunoglobulin Heavy Chain Class Switch Recombination Mechanism
2007
Activation-Induced Cytidine Deaminase-Dependent DNA Breaks in Class Switch Recombination Occur during G1 Phase of the Cell Cycle and Depend upon Mismatch Repair
2007
Hallmarks of Cancer: The Next Generation
2011 Standout
Cell cycle-specific UNG2 phosphorylations regulate protein turnover, activity and association with RPA
2007
Autophagy in infection, inflammation and immunity
2013 Standout
The biochemistry of activation-induced deaminase and its physiological functions
2012
Uracil in DNA—General mutagen, but normal intermediate in acquired immunity
2006
Activation-induced deaminase, AID, is catalytically active as a monomer on single-stranded DNA
2007
Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium
2007 StandoutNobel
Mechanism of somatic hypermutation: Critical analysis of strand biased mutation signatures at A:T and G:C base pairs
2008
The role of the non‐homologous end‐joining pathway in lymphocyte development
2004
Class-switch recombination: interplay of transcription, DNA deamination and DNA repair
2004
Role of AID in Tumorigenesis
2007 StandoutNobel
Down-regulation of DNA polymerase β accompanies somatic hypermutation in human BL2 cell lines
2006
Direct interaction between XRCC1 and UNG2 facilitates rapid repair of uracil in DNA by XRCC1 complexes
2010
Induction of activation-induced cytidine deaminase gene expression by IL-4 and CD40 ligation is dependent on STAT6 and NF B
2004
Histone Modifications Associated with Somatic Hypermutation
2005
B Cell Development Leads Off with a Base Hit
2004
Separate domains of AID are required for somatic hypermutation and class-switch recombination
2004 StandoutNobel
Evolution of the AID/APOBEC Family of Polynucleotide (Deoxy)cytidine Deaminases
2004
DNA Deamination in Immunity: AID in the Context of Its APOBEC Relatives
2007
MDM2 can interact with the C-terminus of AID but it is inessential for antibody diversification in DT40 B cells
2005
Active nuclear import and cytoplasmic retention of activation-induced deaminase
2009
DNA deamination in immunity
2005
Activation-induced Cytosine Deaminase (AID) Is Actively Exported out of the Nucleus but Retained by the Induction of DNA Breaks
2004
Uracil DNA N-Glycosylase Promotes Assembly of Human Centromere Protein A
2011
Transcription-coupled mutagenesis by the DNA deaminase AID.
2004
The generation of antibody diversity through somatic hypermutation and class switch recombination
2004
The dependence of Ig class‐switching on the nuclear export sequence of AID likely reflects interaction with factors additional to Crm1 exportin
2010
Activation-Induced Cytidine Deaminase Links Between Inflammation and the Development of Colitis-Associated Colorectal Cancers
2008 StandoutNobel
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
The mechanisms of immune diversification and their disorders
2003
APOBEC deaminases-mutases with defensive roles for immunity
2009
MRE11/RAD50 Cleaves DNA in the AID/UNG-Dependent Pathway of Immunoglobulin Gene Diversification
2005
A coming-of-age story: activation-induced cytidine deaminase turns 10
2009
Activation-induced cytidine deaminase structure and functions: A species comparative view
2011
The AID/APOBEC family of nucleic acid mutators
2008
Role of genomic instability and p53 in AID-induced c-myc–Igh translocations
2006 Nature
Retroviral restriction by APOBEC proteins
2004
Activation-induced cytidine deaminase: structure–function relationship as based on the study of mutants
2006
The role of activation-induced cytidine deaminase in antibody diversification, immunodeficiency, and B-cell malignancies
2004
Requirement of Non-canonical Activity of Uracil DNA Glycosylase for Class Switch Recombination
2006 StandoutNobel
Expression of activation-induced cytidine deaminase in human hepatocytes via NF-κB signaling
2007 StandoutNobel
Uracil–DNA glycosylases SMUG1 and UNG2 coordinate the initial steps of base excision repair by distinct mechanisms
2007
Somatic hypermutation at A·T pairs: polymerase error versus dUTP incorporation
2005
A Structural Basis for the Biochemical Behavior of Activation-induced Deoxycytidine Deaminase Class-switch Recombination-defective Hyper-IgM-2 Mutants
2012
S-S Synapsis during Class Switch Recombination Is Promoted by Distantly Located Transcriptional Elements and Activation-Induced Deaminase
2007
Evolution of class switch recombination function in fish activation-induced cytidine deaminase, AID
2005 StandoutNobel
The contested role of uracil DNA glycosylase in immunoglobulin gene diversification
2005
Aid
2004 StandoutNobel
An evolutionarily conserved target motif for immunoglobulin class-switch recombination
2004
C-Terminal Deletion of AID Uncouples Class Switch Recombination from Somatic Hypermutation and Gene Conversion
2003
Replication protein A interacts with AID to promote deamination of somatic hypermutation targets
2004 Nature
Repair of U/G and U/A in DNA by UNG2-associated repair complexes takes place predominantly by short-patch repair both in proliferating and growth-arrested cells
2004
The Dark Side of Activation-Induced Cytidine Deaminase: Relationship with Leukemia and Beyond
2006
The Mismatch Repair Protein Msh6 Influences the In Vivo AID Targeting to the Ig Locus
2006
Identification of an AID-independent pathway for chromosomal translocations between the Igh switch region and Myc
2004
Activation-induced Cytidine Deaminase Deaminates 5-Methylcytosine in DNA and Is Expressed in Pluripotent Tissues
2004
AID is expressed in germinal center B-cell-like and activated B-cell-like diffuse large-cell lymphomas and is not correlated with intraclonal heterogeneity
2004
The AID Dilemma
2012 StandoutNobel
Expression of activation‐induced cytidine deaminase in human hepatocytes during hepatocarcinogenesis
2006
Complex regulation and function of activation-induced cytidine deaminase
2011
Activation-induced deaminase: controversies and open questions
2004
SMUG1 is able to excise uracil from immunoglobulin genes: insight into mutation versus repair
2006
Biochemical Analysis of Hypermutational Targeting by Wild Type and Mutant Activation-induced Cytidine Deaminase
2004
Mismatch Recognition and Uracil Excision Provide Complementary Paths to Both Ig Switching and the A/T-Focused Phase of Somatic Mutation
2004
AID Is Required for the Chromosomal Breaks in c-myc that Lead to c-myc/IgH Translocations
2008
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70
2010
Negative regulation of activation-induced cytidine deaminase in B cells
2006 StandoutNobel
Carboxy-terminal domain of AID required for its mRNA complex formation in vivo
2009 StandoutNobel
Accumulation of the FACT complex, as well as histone H3.3, serves as a target marker for somatic hypermutation
2013 StandoutNobel
Mechanisms of double-strand break repair in somatic mammalian cells
2009
Activation-induced cytidine deaminase (AID) promotes B cell lymphomagenesis in Emu-cmyc transgenic mice
2007 StandoutNobel
Nonimmunoglobulin target loci of activation-induced cytidine deaminase (AID) share unique features with immunoglobulin genes
2012 StandoutNobel
Dependence of antibody gene diversification on uracil excision
2007
AID Binds Cooperatively with UNG and Msh2-Msh6 to Ig Switch Regions Dependent upon the AID C Terminus
2011
DNA polymerase β is able to repair breaks in switch regions and plays an inhibitory role during immunoglobulin class switch recombination
2007
Comment on "Uracil DNA Glycosylase Activity Is Dispensable for Immunoglobulin Class Switch"
2004 Science
The stability of AID and its function in class-switching are critically sensitive to the identity of its nuclear-export sequence
2009
Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminase
2015 StandoutNobel
Fine-Structure Analysis of Activation-Induced Deaminase Accessibility to Class Switch Region R-Loops
2005
Decrease in topoisomerase I is responsible for activation-induced cytidine deaminase (AID)-dependent somatic hypermutation
2011 StandoutNobel
Somatic Hypermutation Is Limited by CRM1-dependent Nuclear Export of Activation-induced Deaminase
2004
Molecular mechanism for generation of antibody memory
2008 StandoutNobel
Uracil DNA Glycosylase Disruption Blocks Ig Gene Conversion and Induces Transition Mutations
2006
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination
2009 StandoutNobel
An Evolutionary View of the Mechanism for Immune and Genome Diversity
2012 StandoutNobel
The multifaceted roles of RNA binding in APOBEC cytidine deaminase functions
2014
The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombination
2009 StandoutNobel
PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance
2010 StandoutNobel
Repair and Genetic Consequences of Endogenous DNA Base Damage in Mammalian Cells
2004 StandoutNobel
Epigenetic tethering of AID to the donor switch region during immunoglobulin class switch recombination
2011
Further evidence for involvement of a noncanonical function of uracil DNA glycosylase in class switch recombination
2009 StandoutNobel
Hairy cell leukemia: at the crossroad of somatic mutation and isotype switch
2004
The Biochemistry of Somatic Hypermutation
2008
Molecular Mechanisms of Antibody Somatic Hypermutation
2007
Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylase
2014 StandoutNobel
Separation of Function between Isotype Switching and Affinity Maturation In Vivo during Acute Immune Responses and Circulating Autoantibodies in UNG-Deficient Mice
2013
Structural Phylogenetic Analysis of Activation-Induced Deaminase Function
2006
APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination
2007
DNA cleavage in immunoglobulin somatic hypermutation depends onde novoprotein synthesis but not on uracil DNA glycosylase
2005 StandoutNobel
RNA editing of hepatitis B virus transcripts by activation-induced cytidine deaminase
2013 StandoutNobel
The Double-Edged Sword of Activation-Induced Cytidine Deaminase
2005
Dissociation of in vitro DNA deamination activity and physiological functions of AID mutants
2008 StandoutNobel
Mechanism and Regulation of Class Switch Recombination
2008
Human PMS2 deficiency is associated with impaired immunoglobulin class switch recombination
2008
Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutation
2011 StandoutNobel
53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination
2010
The relationship between hypothesis and experiment in unveiling the mechanisms of antibody gene diversification
2011
Evolutionary Comparison of the Mechanism of DNA Cleavage with Respect to Immune Diversity and Genomic Instability
2012 StandoutNobel
Advantages and Disadvantages of Cytidine Deamination
2004
Recombinogenic Phenotype of Human Activation-Induced Cytosine Deaminase
2004
Overlapping activation-induced cytidine deaminase hotspot motifs in Ig class-switch recombination
2011
Histone3 lysine4 trimethylation regulated by the facilitates chromatin transcription complex is critical for DNA cleavage in class switch recombination
2010 StandoutNobel
Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa
2015 StandoutNobel
APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination
2014 StandoutNobel
Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1
2004 StandoutNobel
Impaired induction of DNA lesions during immunoglobulin class-switch recombination in humans influences end-joining repair
2010
Functional requirements of AID’s higher order structures and their interaction with RNA-binding proteins
2016 StandoutNobel
Apurinic/Apyrimidinic Endonuclease 1 Is the Essential Nuclease during Immunoglobulin Class Switch Recombination
2013
Mechanism of R-Loop Formation at Immunoglobulin Class Switch Sequences
2007
The structure of a yeast RNA-editing deaminase provides insight into the fold and function of activation-induced deaminase and APOBEC-1
2004
Mismatch Repair Proteins MSH2, MLH1, and EXO1 Are Important for Class-Switch Recombination Events Occurring in B Cells That Lack Nonhomologous End Joining
2011
De novo protein synthesis is required for activation-induced cytidine deaminase-dependent DNA cleavage in immunoglobulin class switch recombination
2004 StandoutNobel
DNA Polymerase η Contributes to Strand Bias of Mutations of A versus T in Immunoglobulin Genes
2005
RNA-editing cytidine deaminase Apobec-1 is unable to induce somatic hypermutation in mammalian cells
2003 StandoutNobel
Immunoglobulin Somatic Hypermutation
2007
Inducible DNA breaks in Ig S regions are dependent on AID and UNG
2005
AID to overcome the limitations of genomic information
2005 StandoutNobel
Works of Nadia Catalan being referenced
Hyper-IgM syndrome type 4 with a B lymphocyte–intrinsic selective deficiency in Ig class-switch recombination
2003
Clinical, immunologic and genetic analysis of 29 patients with autosomal recessive hyper-IgM syndrome due to Activation-Induced Cytidine Deaminase deficiency
2003
Human uracil–DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination
2003
AID mutant analyses indicate requirement for class-switch-specific cofactors
2003 StandoutNobel
The Block in Immunoglobulin Class Switch Recombination Caused by Activation-Induced Cytidine Deaminase Deficiency Occurs Prior to the Generation of DNA Double Strand Breaks in Switch μ Region
2003
Mutations ofCD40gene cause an autosomal recessive form of immunodeficiency with hyper IgM
2001
Autophagy inhibition promotes defective neosynthesized proteins storage in ALIS, and induces redirection toward proteasome processing and MHCI-restricted presentation
2012