Citation Impact
Citing Papers
Salt-Sensitive Blood Pressure in Mice With Increased Expression of Aldosterone Synthase
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2008
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1998 StandoutNobel
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1995
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2009 Standout
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2005
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Mouse Behavioral Assays Relevant to the Symptoms of Autism*
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A view on drug resistance in cancer
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2009
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2002 Standout
Mechanisms Underlying Inflammation in Neurodegeneration
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Functional study of rat 5‐HT2A receptors using antisense oligonucleotides
2003
From Threat to Fear: The Neural Organization of Defensive Fear Systems in Humans
2009 StandoutNobel
The Hypothalamic Orexinergic System: Pain and Primary Headaches
2007
Neural regulation of endocrine and autonomic stress responses
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Promotion of sleep by targeting the orexin system in rats, dogs and humans
2007
Schizophrenia
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1993
Physiology and Neurobiology of Stress and Adaptation: Central Role of the Brain
2007 Standout
Functional Selectivity and Classical Concepts of Quantitative Pharmacology
2006 StandoutNobel
5HT drugs in animal models of anxiety
1993
Mechanical, thermal and formalin-induced nociception is differentially altered in 5-HT1A−/−, 5-HT1B−/−, 5-HT2A−/−, 5-HT3A−/− and 5-HTT−/− knock-out male mice
2007 StandoutNobel
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2001
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2011 Standout
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Chronic Pubertal, but not Adult Chronic Cannabinoid Treatment Impairs Sensorimotor Gating, Recognition Memory, and the Performance in a Progressive Ratio Task in Adult Rats
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Evidence that hypophagia induced by d-fenfluramine and d-norfenfluramine in the rat is mediated by 5-HT2C receptors
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Brain angiotensin and anxiety-related behavior: The transgenic rat TGR(ASrAOGEN)680
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Social isolation selectively reduces hippocampal brain-derived neurotrophic factor without altering plasma corticosterone
2006
Examination of drug-induced and isolation-induced disruptions of prepulse inhibition as models to screen antipsychotic drugs
1995
Effects of tonabersat on migraine with aura: a randomised, double-blind, placebo-controlled crossover study
2009
5-Hydroxytryptamine-interacting drugs in animal models of anxiety disorders: More than 30 years of research
1995
Cytoskeletal changes in the hippocampus following restraint stress: Role of serotonin and microtubules
2003
C. elegans Locomotory Rate Is Modulated by the Environment through a Dopaminergic Pathway and by Experience through a Serotonergic Pathway
2000 StandoutNobel
The Non-Antiemetic Uses of Serotonin 5-HT3 Receptor Antagonists
1997
5-HT1A receptor ligands in animal models of anxiety, impulsivity and depression: Multiple mechanisms of action?
1993
Constitutive Activity of the Serotonin2C Receptor InhibitsIn VivoDopamine Release in the Rat Striatum and Nucleus Accumbens
2004
The Role of the Dorsal Hippocampal Serotonergic and Cholinergic Systems in the Modulation of Anxiety
2000
Acute Selective Serotonin Reuptake Inhibitors Increase Conditioned Fear Expression: Blockade With a 5-HT2C Receptor Antagonist
2007
Effect of 3β-hydroxysteroid dehydrogenase inhibition by trilostane on blood pressure in the Dahl salt-sensitive rat
2004
Non-genomic effects of glucocorticoids in the neural system
2001
The Selective Serotonin2A Receptor Antagonist, MDL100,907, Elicits a Specific Interoceptive Cue in Rats
2002
Novelty and Anxiolytic Drugs Dissociate Two Components of Hippocampal Theta in Behaving Rats
2013 StandoutNobel
Development, maintenance and disruption of the blood-brain barrier
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Stress signalling pathways that impair prefrontal cortex structure and function
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The Serotonin Syndrome
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Glial and neuronal control of brain blood flow
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The selective serotonin (5-HT)1A receptor ligand, S15535, displays anxiolytic-like effects in the social interaction and Vogel models and suppresses dialysate levels of 5-HT in the dorsal hippocampus of freely-moving rats
2000
Differential modulation of nociceptive dural input to [hypocretin] orexin A and B receptor activation in the posterior hypothalamic area
2004
The elevated T-maze as an experimental model of anxiety
1998
In vivoproperties of SB 200646A, a 5‐HT2C/2Breceptor antagonist
1994
Emerging Biological Principles of Metastasis
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1993
Selective blockade of serotonin2C/2B receptors enhances dopamine release in the rat nucleus accumbens
1998
Environmental animal models for sensorimotor gating deficiencies in schizophrenia: a review
2001
Neuroligin-1 Deletion Results in Impaired Spatial Memory and Increased Repetitive Behavior
2010 StandoutNobel
5‐HT 2C receptor modulation and the treatment of obesity
1999
Teaching old receptors new tricks: biasing seven-transmembrane receptors
2010 StandoutNobel
The spectrum of behaviors influenced by serotonin
1998
Orexin receptors as therapeutic drug targets
2012
Current practice and future directions in the prevention and acute management of migraine
2010
A review of central 5-HT receptors and their function
1999 Standout
Physiology of Local Renin-Angiotensin Systems
2006 Standout
Major Depressive Disorder
2008 Standout
Carcinoma–astrocyte gap junctions promote brain metastasis by cGAMP transfer
2016 Nature
Opposing Roles for 5-HT2A and 5-HT2C Receptors in the Nucleus Accumbens on Inhibitory Response Control in the 5-Choice Serial Reaction Time Task
2007
Dissociable Effects of Selective 5-HT2A and 5-HT2C Receptor Antagonists on Serial Spatial Reversal Learning in Rats
2007
Serotonin and Hallucinogens
1999
Suppression of cortical spreading depression in migraine prophylaxis
2006
Modern Synthetic Methods for Fluorine‐Substituted Target Molecules
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Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review
2007 Standout
Orexin Receptor Antagonists: A New Concept In CNS Disorders?
2010
The Endophenotype Concept in Psychiatry: Etymology and Strategic Intentions
2003 Standout
Functional Selectivity of Hallucinogenic Phenethylamine and Phenylisopropylamine Derivatives at Human 5-Hydroxytryptamine (5-HT)2A and 5-HT2C Receptors
2007
Effects of 5-HT4 receptor antagonists on rat behaviour in the elevated plus-maze test
1996
Orexins and appetite regulation
2002
Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety
1999 Standout
Behavioural and hypothalamic molecular effects of the anti-cancer agent cisplatin in the rat: A model of chemotherapy-related malaise?
2006 StandoutNobel
Ghrelin: Structure and Function
2005 Standout
Endogenous serotonin and serotonin2Creceptors are involved in the ability of M100907 to suppress cortical glutamate release induced by NMDA receptor blockade
2008
Discriminative stimulus properties of the novel serotonin (5-HT)2C receptor agonist, RO60-0175: a pharmacological analysis
1999
Modulation of nociceptive dural input to the trigeminal nucleus caudalis via activation of the orexin 1 receptor in the rat
2006
Behavioural and pharmacological characterisation of the elevated “zero-maze” as an animal model of anxiety
1994
Effects of systemic and intra-nucleus accumbens 5-HT2C receptor compounds on ventral tegmental area self-stimulation thresholds in rats
2008
Anxiolytic properties of agomelatine, an antidepressant with melatoninergic and serotonergic properties: role of 5-HT2C receptor blockade
2004
Anxiolytic-like Actions of the Selective 5-HT 4 Receptor Antagonists SB 204070A and SB 207266A in Rats
1997
Serotonin (5-HT)2C receptors tonically inhibit dopamine (DA) and noradrenaline (NA), but not 5-HT, release in the frontal cortex in vivo
1998
Effects of the 5‐HT2B receptor agonist, BW 723C86, on three rat models of anxiety
1996
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Gravity Force Transduced by the MEC-4/MEC-10 DEG/ENaC Channel Modulates DAF-16/FoxO Activity in Caenorhabditis elegans
2007 StandoutNobel
The Blood-Brain Barrier in Migraine Treatment
2008
Serotonin in Affective Control
2009
The 5-HT3Subtype of Serotonin Receptor Contributes to Nociceptive Processing via a Novel Subset of Myelinated and Unmyelinated Nociceptors
2002 StandoutNobel
Marine Indole Alkaloids: Potential New Drug Leads for the Control of Depression and Anxiety
2010 Standout
Catalytic Staudinger/Aza‐Wittig Sequence by in situ Phosphane Oxide Reduction
2013
RNA Editing of the Human Serotonin 5-HT2C Receptor Alterations in Suicide and Implications for Serotonergic Pharmacotherapy
2001
Phosphine Organocatalysis
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Migraine aura: new information on underlying mechanisms
2004
Effect produced by acute and chronic administration of the selective 5‐HT3 receptor antagonist BRL 46470 on the number of spontaneously active midbrain dopamine cells in the rat
1994
TheC. elegansPOU-domain transcription factor UNC-86 regulates thetph-1tryptophan hydroxylase gene and neurite outgrowth in specific serotonergic neurons
2002 StandoutNobel
Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function
2011 StandoutNobel
The Multiplicity of Serotonin Receptors: Uselessly Diverse Molecules or an Embarrassment of Riches?
2000
Pivotal mental states
2020
Biomedical Application of Orexin/Hypocretin Receptor Ligands in Neuroscience
2009
KCl-induced repetitive cortical spreading depression inhibiting trigeminal neuronal firing is mediated by 5-HT1B/1D and opioid receptors
2022
Therapeutic Potential of Serotonin 5-HT3 Antagonists in Neuropsychiatric Disorders
1995
Risky families: Family social environments and the mental and physical health of offspring.
2002 Standout
Emerging drugs for schizophrenia
2008
The Role of Hypocretins (Orexins) in Sleep Regulation and Narcolepsy
2002
Serotonin receptor knockouts: A moody subject
1998 StandoutNobel
Requirement of Hippocampal Neurogenesis for the Behavioral Effects of Antidepressants
2003 StandoutScience
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Association of Anxiety-Related Traits with a Polymorphism in the Serotonin Transporter Gene Regulatory Region
1996 StandoutScience
The pharmacology of the hypothermic response in mice to 8-hydroxy-2-(DI-n-propylamino)tetralin (8-OH-DPAT)
1985
Evidence That 5-HT2AReceptors in the Hypothalamic Paraventricular Nucleus Mediate Neuroendocrine Responses to (−)DOI
2002
Antiestrogens and Selective Estrogen Receptor Modulators as Multifunctional Medicines. 2. Clinical Considerations and New Agents
2003
Behavioural and neurochemical effects of early social deprivation in the rat
1996
Mouse neurexin-1α deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments
2009 StandoutNobel
Works of N. Upton being referenced
Effect of a selective OX1R antagonist on food intake and body weight in two strains of rats that differ in susceptibility to dietary-induced obesity
2005
Recent developments from genetic mouse models of seizures
2003
Comparison of acute and chronic treatment of various serotonergic agents with those of diazepam and idazoxan in the rat elevated X-maze
1992
Effect of isolation rearing on 5-HT agonist-induced responses in the rat
1991
Differential effects of the selective orexin-1 receptor antagonist SB-334867 and lithium chloride on the behavioural satiety sequence in rats
2004
SB 242084, a Selective and Brain Penetrant 5-HT 2C Receptor Antagonist
1997
SB‐334867, a selective orexin‐1 receptor antagonist, enhances behavioural satiety and blocks the hyperphagic effect of orexin‐A in rats
2001
Clozapine enhances breakpoint in common marmosets responding on a progressive ratio schedule
2001
Synthesis and evaluation of a series of aryl[e]fused pyrazolo[4,3-c]pyridines with potential anxiolytic activity
1990
Orexin-A, an hypothalamic peptide with analgesic properties
2001
The PPARγ agonist pioglitazone is effective in the MPTP mouse model of Parkinson's disease through inhibition of monoamine oxidase B
2008
Anorexia and weight loss in male rats 24h following single dose treatment with orexin-1 receptor antagonist SB-334867
2004
Evidence implicating a role for orexin-1 receptor modulation of paradoxical sleep in the rat
2003
Increased cortical expression of the orexin-1 receptor following permanent middle cerebral artery occlusion in the rat
2002
Satiety enhancement by selective orexin-1 receptor antagonist SB-334867: influence of test context and profile comparison with CCK-8S
2004
BRL 46470A: a highly potent, selective and long acting 5-HT3 receptor antagonist with anxiolytic-like properties
1993
Resocialisation of isolation-reared rats does not alter their anxiogenic profile on the elevated X-maze model of anxiety
1991
Repetitive Cortical Spreading Depression in a Gyrencephalic Feline Brain: Inhibition by the Novel Benzoylamino-Benzopyran SB-220453
2000
Characterization of a κ-agonist-like antinociceptive action of tifluadom
1983
The Potential Anti-Migraine Compound SB-220453 does not Contract Human Isolated Blood Vessels or Myocardium; A Comparison with Sumatriptan
2000
Effect of established and putative anxiolytics on extracellular 5-HT and 5-HIAA in the ventral hippocampus of rats during behaviour on the elevated X-maze
1992
SB-220453, A Potential Novel Antimigraine Agent, Inhibits Nitric Oxide Release Following Induction of Cortical Spreading Depression in the Anaesthetized Cat
2000