Citation Impact
Citing Papers
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
Spinophilin Blocks Arrestin Actions in Vitro and in Vivo at G Protein-Coupled Receptors
2004 StandoutScienceNobel
Pathophysiology of Migraine: A Disorder of Sensory Processing
2017 Standout
Abnormal Regulation of the Sympathetic Nervous System in α2A-Adrenergic Receptor Knockout Mice
1999 StandoutNobel
Release‐Regulating Serotonin 5‐HT1D Autoreceptors in Human Cerebral Cortex
1993
GR127935: a potent and selective 5-HT1D receptor antagonist
1995
Adrenergic α2C-Receptors Modulate the Acoustic Startle Reflex, Prepulse Inhibition, and Aggression in Mice
1998 StandoutNobel
Subtypes of functional α1- and α2-adrenoceptors
1998
Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
1996 StandoutNature
Transgenic models of α2-adrenergic receptor subtype function
2008
Gene Substitution/Knockout to Delineate the Role of α2‐Adrenoceptor Subtypes in Mediating Central Effects of Catecholamines and Imidazolines
1999 StandoutNobel
Neural ATP release and its α2-adrenoceptor-mediated modulation in guinea-pig vas deferens
1993
Altered Beta-adrenergic Receptor Gene Regulation and Signaling in Chronic Heart Failure
2001
Characterization of [3H]GABA release from striatal slices: Evidence for a calcium-independent process via the GABA uptake system
1988
(+)‐WAY 100135, a partial agonist, at native and recombinant 5‐HT1B/1D receptors
1997
Distinct 5-HT1B and 5-HT1D serotonin receptors in rat: Structural and pharmacological comparison of the two cloned receptors
1992
Neurochemistry and pharmacology of the major hippocampal transmitter systems: Synaptic and nonsynaptic interactions
1998
Getting Formal with Dopamine and Reward
2002 Standout
Postsynaptic Integration of Cholinergic and Dopaminergic Signals on Medium-Sized GABAergic Projection Neurons in the Neostriatum
1998
Evaluation of the effects of a specific α2-adrenoceptor antagonist, atipamezole, on α1- and α2-adrenoceptor subtype binding, brain neurochemistry and behaviour in comparison with yohimbine
1997
Contraction-mediating α2-adrenoceptors in the mouse vas deferens
1991
Glutamate uptake
2001 Standout
Localization ofα2c-adrenergic receptor immunoreactivity in catecholaminergic neurons in the rat central nervous system
1998
Cell-type Specific Targeting of the α2c-Adrenoceptor
2000 StandoutNobel
The serotonergic and noradrenergic systems of the hippocampus: their interactions and the effects of antidepressant treatments
1997
P2 receptor-mediated inhibition of dopamine release in rat neostriatum
2000
5-HT1D-like receptors inhibit the release of endogenously formed [3H]GABA in human, but not in rabbit, neocortex
1996
Differential Distribution of [ 3 H]Sumatriptan Binding Sites (5-HT 1B , 5-HT 1D and 5-HT 1F Receptors) in Human Brain: Focus on Brainstem and Spinal Cord
1997
Involvement of peripheral presynaptic inhibition in the reduction of sympathetic tone by moxonidine, rilmenidine and UK 14304
1995
Co-release of endogenous ATP and [3H]noradrenaline from rat hypothalamic slices: origin and modulation by α2-adrenoceptors
1997
Evidence for P2‐purinoceptor‐mediated inhibition of noradrenaline release in rat brain cortex
1994
Alpha2C-adrenoceptor overexpression disrupts execution of spatial and non-spatial search patterns
1999 StandoutNobel
Subtype-specificity of the presynaptic α2-adrenoceptors modulating hippocampal norepinephrine release in rat
1995
α 2-Adrenergic receptor subtypes in rat dorsal root and superior cervical ganglion neurons
1997
Theta Oscillations in the Hippocampus
2002 Standout
Abnormal Regulation of the Sympathetic Nervous System in α2A-Adrenergic Receptor Knockout Mice
1999 StandoutNobel
Heat Shock Protein A12B Protects Vascular Endothelial Cells Against Sepsis-Induced Acute Lung Injury in Mice
2017 Standout
Chapter 14: Transmitter release: target of regulation by protein kinase C?
1991
Effects of selective h5-HT1B (SB-216641) and h5-HT1D (BRL-15572) receptor ligands on guinea-pig and human 5-HT auto- and heteroreceptors
1997
Localization of 5-HT1B, 5-HT1Dα, 5-HT1E and 5-HT1F receptor messenger RNA in rodent and primate brain
1994
Synthesis and Release of Dopamine in Rat Brain: Comparison Between Substantia Nigra Pars Compacta, Pars Reticulata, and Striatum
1989 StandoutNobel
Gene targeting — homing in on α2-adrenoceptor-subtype function
1997 StandoutNobel
Dynamic Observation of Dopamine Autoreceptor Effects in Rat Striatal Slices
1992
Dopamine D1 Agonist SKF 38393 Increases the State of Phosphorylation of ARPP‐21 in Substantia Nigra
1993 StandoutNobel
Investigation of the subtypes of α2-adrenoceptor mediating prejunctional inhibition in rat atrium and cerebral cortex
1998
Distribution of ?2C-adrenergic receptor-like immunoreactivity in the rat central nervous system
1996
From sensation to cognition
1998 Standout
Two functionally distinct α2-adrenergic receptors regulate sympathetic neurotransmission
1999 StandoutNatureNobel
Cultured chick sympathetic neurons: modulation of electrically evoked noradrenaline release by P2-purinoceptors
1995
Continuousin vivo monitoring of evoked dopamine release in the rat nucleus accumbens by amperometry
1994
Autoradiographic localization of dopamine D1 and D2 receptors in rat nucleus accumbens: Resistance to differential rearing conditions
1991 Standout
Subtype determination of presynaptic ?2-autoreceptors in the rabbit pulmonary artery and human saphenous vein
1995
Presynaptic ?2-autoreceptors in mouse heart atria: evidence for the ?2D subtype
1996
Characterization of the 5‐Hydroxytryptamine Receptor Modulating the Release of 5‐[3H]Hydroxytryptamine in Slices of the Human Neocortex
1992
α2‐Adrenoceptors modulating neuronal serotonin release: a study in α2‐adrenoceptor subtype‐deficient mice
2001
Physiology and Pathophysiology of Purinergic Neurotransmission
2007 Standout
A subfamily of 5-HT1D receptor genes
1992
Effects of the 5-HT1D receptor antagonist GR127935 on extracellular levels of 5-HT in the guinea-pig frontal cortex as measured by microdialysis
1995
ATP release in human kidney cortex and its mitogenic effects in visceral glomerular epithelial cells
2002
Serotonin receptors: Subtypes, functional responses and therapeutic relevance
1995
Geometry, kinetics and plasticity of release and clearance of ATP and noradrenaline as sympathetic cotransmitters: Roles for the neurogenic contraction
1995
Munc13-1 Is a Presynaptic Phorbol Ester Receptor that Enhances Neurotransmitter Release
1998 StandoutNobel
Behavioral and neurochemical characterization of α2A-adrenergic receptor knockout mice
2002 StandoutNobel
α2-Adrenoceptors: more subtypes but fewer functional differences
1994
A review of central 5-HT receptors and their function
1999 Standout
Importance of quantitative genetic variations in the etiology of hypertension
2000 StandoutNobel
The molecular logic of endocannabinoid signalling
2003 Standout
5-HT4 receptor involvement in the serotonin-enhanced dopamine efflux from the substantia nigra of the freely moving rat: a microdialysis study
1998
A re-investigation of questionable subclassifications of presynaptic α2-autoreceptors: rat vena cava, rat atria, human kidney and guinea-pig urethra
1997
Expression of α2 adrenoceptors during rat brain development—I. α2A messenger RNA expression
1996
Investigation of the subtype of α2‐adrenoceptor mediating prejunctional inhibition of cardioacceleration in the pithed rat heart
1995
d-amphetamine and l-5-hydroxytryptophan-induced behaviours in mice with genetically-altered expression of the α2C-adrenergic receptor subtype
1998 StandoutNobel
5-HT3 receptors in the rat central nervous system are mainly located on nerve fibres and terminals
1993
5-Hydroxytryptamine receptor subtypes in vertebrates and invertebrates
1994
α2-Adrenoceptors and I2 sites in the mammalian central nervous system
1995
Importance of h5-HT 1B Receptor Selectivity for 5-HT Terminal Autoreceptor Activity: an In Vivo Microdialysis Study in the Freely-moving Guinea-pig
1997
Regulation of transient dopamine concentration gradients in the microenvironment surrounding nerve terminals in the rat striatum
1992
Subtype classification of presynaptic α2-adrenoceptors
1993
A Resource of Cre Driver Lines for Genetic Targeting of GABAergic Neurons in Cerebral Cortex
2011 Standout
Linkage of β1-adrenergic stimulation to apoptotic heart cell death through protein kinase A–independent activation of Ca2+/calmodulin kinase II
2003 StandoutNobel
Vascular α-adrenoceptors: from the gene to the human
1995
Uropathic Observations in Mice Expressing a Constitutively Active Point Mutation in the 5-HT3AReceptor Subunit
2004 StandoutNobel
Autoradiographic characterisation and localisation of 5-HT1D compared to 5-HT1B binding sites in rat brain
1993
Opposing Roles of Dopamine D1 and D2 Receptors in Nigral γ‐[3H]Aminobutyric Acid Release?
1987
Role of High-Affinity Receptors and Membrane Transporters in Nonsynaptic Communication and Drug Action in the Central Nervous System
2000
Cholesterol increases kinetic, energetic, and mechanical stability of the human β2-adrenergic receptor
2012 StandoutNobel
The 5-HT3Subtype of Serotonin Receptor Contributes to Nociceptive Processing via a Novel Subset of Myelinated and Unmyelinated Nociceptors
2002 StandoutNobel
Ultrastructural evidence for prominent postsynaptic localization of ?2C-adrenergic receptors in catecholaminergic dendrites in the rat nucleus locus coeruleus
1998
Inactivation of a Serotonin-Gated Ion Channel by a Polypeptide Toxin from Marine Snails
1998 StandoutScienceNobel
Functional Domains in Dorsal Striatum of the Nonhuman Primate Are Defined by the Dynamic Behavior of Dopamine
2002
Myocyte Adrenoceptor Signaling Pathways
2003 StandoutScienceNobel
Ultrastructural localization of D2 receptor-like immunoreactivity in midbrain dopamine neurons and their striatal targets
1994
Heterozygous α 2A -adrenergic receptor mice unveil unique therapeutic benefits of partial agonists
2002 StandoutNobel
Evidence for presynaptic location of inhibitory 5-HT1D\-like autoreceptors in the guinea-pig brain cortex
1996
α2-Adrenergic receptors in human spinal cord: specific localized expression of mRNA encoding α2-adrenergic receptor subtypes at four distinct levels
1995
Substitution of a mutant α 2a -adrenergic receptor via “hit and run” gene targeting reveals the role of this subtype in sedative, analgesic, and anesthetic-sparing responses in vivo
1997
Predictive Reward Signal of Dopamine Neurons
1998 Standout
Linkage of β1-adrenergic stimulation to apoptotic heart cell death through protein kinase A–independent activation of Ca2+/calmodulin kinase II
2003 StandoutNobel
Mutation of the α2A-Adrenoceptor Impairs Working Memory Performance and Annuls Cognitive Enhancement by Guanfacine
2002 StandoutNobel
Antinociceptive Action of Nitrous Oxide Is Mediated by Stimulation of Noradrenergic Neurons in the Brainstem and Activation of α2BAdrenoceptors
2000 StandoutNobel
Structure-based discovery of β 2 -adrenergic receptor ligands
2009 StandoutNobel
Distribution of ?2A-adrenergic receptor-like immunoreactivity in the rat central nervous system
1996
Presynaptically Located CB1 Cannabinoid Receptors Regulate GABA Release from Axon Terminals of Specific Hippocampal Interneurons
1999 Standout
The Sympathetic Nerve—An Integrative Interface between Two Supersystems: The Brain and the Immune System
2000 Standout
Neuronal Diversity and Temporal Dynamics: The Unity of Hippocampal Circuit Operations
2008 StandoutScience
INSIGHTS FROM IN VIVO MODIFICATION OF ADRENERGIC RECEPTOR GENE EXPRESSION
1998 StandoutNobel
S18616, a highly potent spiroimidazoline agonist at alpha(2)-adrenoceptors: II. Influence on monoaminergic transmission, motor function, and anxiety in comparison with dexmedetomidine and clonidine.
2000
Gene targeting — homing in on α2-adrenoceptor-subtype function
1997 StandoutNobel
Efflux of dopamine from the synaptic cleft in the nucleus accumbens of the rat brain
1994
Why are there so many adrenoceptor subtypes?
1994
Role of the α2B-Adrenergic Receptor in the Development of Salt-Induced Hypertension
1999 StandoutNobel
Works of N. Limberger being referenced
Alpha 2-adrenergic receptors of the alpha 2c subtype mediate inhibition of norepinephrine release in human kidney cortex.
1994
Pharmacological characterization of presynaptic α2‐autoreceptors in rat submaxillary gland and heart atrium
1992
Subclassification of presynaptic ?2-adrenoceptors: ?2D-autoreceptors in guinea-pig atria and brain
1995
Species differences in presynaptic serotonin autoreceptors: mainly 5-HT1B but possibly in addition 5-HT1D in the rat, 5-HT1D in the rabbit and guinea-pig brain cortex
1991
Subclassification of presynaptic ?2-adrenoceptors: ?2D-autoreceptors and ?2D-adrenoceptors modulating release of acetylcholine in guinea-pig ileum
1995
Presynaptic ?2A-adrenoceptors inhibit the release of endogenous dopamine in rabbit caudate nucleus slices
1994
Estimation ofpA2 values at presynaptic ?2-autoreceptors in rabbit and rat brain cortex in the absence of autoinhibition
1989
Release-inhibiting ?2-adrenoceptors at serotonergic axons in rat and rabbit brain cortex: evidence for pharmacological identity with ?2-autoreceptors
1994
Acetylcholine release in rat nucleus accumbens is regulated through dopamine D2-receptors
1988
Serotonin uptake blockers influence serotonin autoreceptors by increasing the biophase concentration of serotonin and not through a ?molecular link?
1990
Subclassification of the presynaptic α2‐autoreceptors in rabbit brain cortex
1991
α2c‐Adrenoceptor‐modulated release of noradrenaline in human right atrium
1995
Subclassification of presynaptic ?2-adrenoceptors: ?2A-autoreceptors in rabbit atria and kidney
1995
Presynaptic ?2-adrenoceptor, opioid ?-receptor and adenosine A1-receptor interactions on noradrenaline release in rabbit brain cortex
1988
Phentolamine blocks presynaptic serotonin autoreceptors in rabbit and rat brain cortex
1989
Subclassification of presynaptic ?2-adrenoceptors: ?2D-autoreceptors in mouse brain
1995
Presynaptic ?2-autoreceptors in brain cortex: ?2D in the rat and ?2A in the rabbit
1993
Transmitter release patterns of noradrenergic, dopaminergic and cholinergic axons in rabbit brain slices during short pulse trains, and the operation of presynaptic autoreceptors
1988
Autoreceptors and ?2-adrenoceptors at the serotonergic axons of rabbit brain cortex
1986
The transmitter release pattern of serotonin axons in rabbit brain cortex slices during short pulse trains
1990
?Real time? measurement of endogenous dopamine release during short trains of pulses in slices of rat neostriatum and nucleus accumbens : role of autoinhibition
1991
A Search for Receptors Modulating the Release of γ‐[3H]Aminobutyric Acid in Rabbit Caudate Nucleus Slices
1986
Release of Previously Incorporated γ‐[3H]Aminobutyric Acid in Rabbit Caudate Nucleus Slices
1986
Partial agonist effect of 2-[2-(1,4-Benzodioxanyl)]-2-imidazoline (RX 781094) at presynaptic ?2-adrenoceptors in rabbit ear artery
1983
The presynaptic alpha-2 autoreceptors in pig brain cortex are alpha-2A.
1996
Further study of prerequisites for the enhancement by ?-adrenoceptor antagonists of the release of noradrenaline
1984