Citation Impact
Citing Papers
X11L2, a New Member of the X11 Protein Family, Interacts with Alzheimer's β-Amyloid Precursor Protein
1999
Insulin Stimulates the Phosphorylation of the 66- and 52-Kilodalton Shc Isoforms by Distinct Pathways1
1997
A Lipid-Anchored Grb2-Binding Protein That Links FGF-Receptor Activation to the Ras/MAPK Signaling Pathway
1997
The Shc adaptor protein is highly phosphorylated at conserved, twin tyrosine residues (Y239/240) that mediate protein–protein interactions
1996
The PTB domain: a new protein module implicated in signal transduction
1995
X11 Interaction with β-Amyloid Precursor Protein Modulates Its Cellular Stabilization and Reduces Amyloid β-Protein Secretion
1998
CASK and Protein 4.1 Support F-actin Nucleation on Neurexins
2001 StandoutNobel
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Structure and ligand recognition of the phosphotyrosine binding domain of Shc
1995 Nature
Go-protein α-Subunits Activate Mitogen-activated Protein Kinase via a Novel Protein Kinase C-dependent Mechanism
1996 StandoutNobel
Specificity of the PTB Domain of Shc for β Turn-forming Pentapeptide Motifs Amino-terminal to Phosphotyrosine
1995
A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides
1995
Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides
1996 StandoutNature
The PDZ Binding Motif of the β1 Adrenergic Receptor Modulates Receptor Trafficking and Signaling in Cardiac Myocytes
2002 StandoutNobel
The language of covalent histone modifications
2000 StandoutNature
Viral Protein R Regulates Docking of the HIV-1 Preintegration Complex to the Nuclear Pore Complex
1998 StandoutNobel
Identification of an Evolutionarily Conserved Heterotrimeric Protein Complex Involved in Protein Targeting
1998
G Protein-coupled Receptors Mediate Two Functionally Distinct Pathways of Tyrosine Phosphorylation in Rat 1a Fibroblasts
1997 StandoutNobel
Structural basis for IL-4 receptor phosphopeptide recognition by thelRS-1 PTB domain
1996
The Regions of the Fe65 Protein Homologous to the Phosphotyrosine Interaction/Phosphotyrosine Binding Domain of Shc Bind the Intracellular Domain of the Alzheimer's Amyloid Precursor Protein
1995
The G Protein-coupled Receptor CL1 Interacts Directly with Proteins of the Shank Family
2000 StandoutNobel
Recognition and specificity in protein tyrosine kinase-mediated signalling
1995
Tyrosine Phosphorylation of the β-Amyloid Precursor Protein Cytoplasmic Tail Promotes Interaction with Shc
2002
Rational design of α-helical tandem repeat proteins with closed architectures
2015 StandoutNatureNobel
Interaction of Cytosolic Adaptor Proteins with Neuronal Apolipoprotein E Receptors and the Amyloid Precursor Protein
1998
HIV nuclear import is governed by the phosphotyrosine-mediated binding of matrix to the core domain of integrase
1995
The β2-Adrenergic Receptor Mediates Extracellular Signal-regulated Kinase Activation via Assembly of a Multi-receptor Complex with the Epidermal Growth Factor Receptor
2000 StandoutNobel
Protein modules and signalling networks
1995 StandoutNature
Regulation of Membrane Targeting of the G Protein-coupled Receptor Kinase 2 by Protein Kinase A and Its Anchoring Protein AKAP79
2001 StandoutNobel
PDZ Domains: Targeting signalling molecules to sub‐membranous sites
1997
Oxidants, oxidative stress and the biology of ageing
2000 StandoutNature
Modular peptide binding: From a comparison of natural binders to designed armadillo repeat proteins
2013
Ras-dependent Mitogen-activated Protein Kinase Activation by G Protein-coupled Receptors
1997 StandoutNobel
A Novel Multiple PDZ Domain-containing Molecule Interacting withN-Methyl-d-aspartateReceptors and Neuronal Cell Adhesion Proteins
1998 StandoutNobel
Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway
1997
Shc Isoform-specific Tyrosine Phosphorylation by the Insulin and Epidermal Growth Factor Receptors
1995
Cross-Intron Bridging Interactions in the Yeast Commitment Complex Are Conserved in Mammals
1997 StandoutNobel
CASK Functions as a Mg2+-Independent Neurexin Kinase
2008 StandoutNobel
β-Arrestins Regulate Mitogenic Signaling and Clathrin-mediated Endocytosis of the Insulin-like Growth Factor I Receptor
1998 StandoutNobel
GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5
2003 StandoutNature
Role of IRS-2 in insulin and cytokine signalling
1995 Nature
The X11α Protein Slows Cellular Amyloid Precursor Protein Processing and Reduces Aβ40 and Aβ42 Secretion
1998
CED-1 Is a Transmembrane Receptor that Mediates Cell Corpse Engulfment in C. elegans
2001 StandoutNobel
A Tripartite Protein Complex with the Potential to Couple Synaptic Vesicle Exocytosis to Cell Adhesion in Brain
1998 StandoutNobel
Three-dimensional segregation of supramolecular activation clusters in T cells
1998 StandoutNature
Modulation of Amyloid Precursor Protein Metabolism by X11α/Mint-1
2000
Mints as Adaptors
2000 StandoutNobel
Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain
1997
Mints, Munc18-interacting Proteins in Synaptic Vesicle Exocytosis
1997 StandoutNobel
Proteomics to study genes and genomes
2000 StandoutNature
GTPase Activating Specificity of RGS12 and Binding Specificity of an Alternatively Spliced PDZ (PSD-95/Dlg/ZO-1) Domain
1998 StandoutNobel
The intracellular cytoplasmic domain of the Alzheimer's disease amyloid precursor protein interacts with phosphotyrosine‐binding domain proteins in the yeast two‐hybrid system
1996
Role of c-Src Tyrosine Kinase in G Protein-coupled Receptorand Gβγ Subunit-mediated Activation of Mitogen-activated Protein Kinases
1996 StandoutNobel
Peptide recognition by PTB and PDZ domains
1997
Candidate Adaptor Protein CED-6 Promotes the Engulfment of Apoptotic Cells in C. elegans
1998
Crystal Structures of a Complexed and Peptide-Free Membrane Protein–Binding Domain: Molecular Basis of Peptide Recognition by PDZ
1996 StandoutNobel
The p66shc adaptor protein controls oxidative stress response and life span in mammals
1999 StandoutNature
The Phosphotyrosine Interaction Domains of X11 and FE65 Bind to Distinct Sites on the YENPTY Motif of Amyloid Precursor Protein
1996
The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules.
1995
The PTB Domain: The Name Doesn't Say It All
1999
High-affinity binding of the Drosophila Numb phosphotyrosine-binding domain to peptides containing a Gly-Pro-(p)Tyr motif
1997
Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway
1995 StandoutNatureNobel
MODULAR PEPTIDE RECOGNITION DOMAINS IN EUKARYOTIC SIGNALING
1997
Tyrosine Phosphorylation of Transmembrane Ligands for Eph Receptors
1997 StandoutScience
Deletion of CASK in mice is lethal and impairs synaptic function
2007 StandoutNobel
The Disabled 1 Phosphotyrosine-Binding Domain Binds to the Internalization Signals of Transmembrane Glycoproteins and to Phospholipids
1999
Signaling Through Scaffold, Anchoring, and Adaptor Proteins
1997 StandoutScience
Mass spectrometry-based proteomics
2003 StandoutNature
G protein beta gamma subunits stimulate phosphorylation of Shc adapter protein.
1995 StandoutNobel
SH2 and PTB Domains in Tyrosine Kinase Signaling
2003
Binding of F-spondin to amyloid-β precursor protein: A candidate amyloid-β precursor protein ligand that modulates amyloid-β precursor protein cleavage
2004 StandoutNobel
Integrins and Signal Transduction Pathways: the Road Taken
1995 StandoutScience
Autosomal Recessive Hypercholesterolemia Caused by Mutations in a Putative LDL Receptor Adaptor Protein
2001 Science
Critical role of reverse transcriptase in the inhibitory mechanism of CNI-H0294 on HIV-1 nuclear translocation.
1996 StandoutNobel
Cytokine Signaling Through Nonreceptor Protein Tyrosine Kinases
1995 StandoutScience
Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein, with homology to Eag and cyclic nucleotide-gated channels
1997 StandoutNobel
daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans
1997 StandoutScienceNobel
Fe65L2: a new member of the Fe65 protein family interacting with the intracellular domain of the Alzheimer's β-amyloid precursor protein
1998
Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells
2001 StandoutNobel
Vitamin B 2 -based blue-light photoreceptors in the retinohypothalamic tract as the photoactive pigments for setting the circadian clock in mammals
1998 StandoutNobel
Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the β1-adrenergic receptor
1999 StandoutNobel
In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector
1996 StandoutScience
Analysis of receptor signaling pathways by mass spectrometry: Identification of Vav-2 as a substrate of the epidermal and platelet-derived growth factor receptors
2000
Stimulation of growth factor receptor signal transduction by activation of voltage-sensitive calcium channels.
1996
Identification of residues that control specific binding of the Shc phosphotyrosine-binding domain to phosphotyrosine sites.
1996
A role for Mints in transmitter release: Mint 1 knockout mice exhibit impaired GABAergic synaptic transmission
2003 StandoutNobel
IRS-1-Mediated Inhibition of Insulin Receptor Tyrosine Kinase Activity in TNF-α- and Obesity-Induced Insulin Resistance
1996 StandoutScience
Phosphotyrosine-Dependent Interaction of SHC and Insulin Receptor Substrate 1 with the NPEY Motif of the Insulin Receptor via a Novel Non-SH2 Domain
1995
Cleavage of Amyloid-β Precursor Protein and Amyloid-β Precursor-like Protein by BACE 1
2004 StandoutNobel
Works of N Li being referenced
A region in Shc distinct from the SH2 domain can bind tyrosine-phosphorylated growth factor receptors.
1994