N E Rosenthal

Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet

The effect of mindfulness-based therapy on anxiety and depression: A meta-analytic review.

Acute and Longer-Term Outcomes in Depressed Outpatients Requiring One or Several Treatment Steps: A STAR*D Report

Cryptochrome, Circadian Cycle, Cell Cycle Checkpoints, and Cancer

The cryb Mutation Identifies Cryptochrome as a Circadian Photoreceptor in Drosophila

Seasonal affective disorder and latitude: a review of the literature

Seasonal Affective Disorder: An Overview

Transcriptional architecture of the mammalian circadian clock

Emotion-regulation strategies across psychopathology: A meta-analytic review

Measuring and using light in the melanopsin age

Molecular Bases for Circadian Clocks

Evidence for Genetic Influences on Sleep Disturbance and Sleep Pattern in Twins

Melanin Pigmentation in Mammalian Skin and Its Hormonal Regulation

Childhood and Adolescent Depression: A Review of the Past 10 Years. Part I

Are the Dorsal and Ventral Hippocampus Functionally Distinct Structures?

The Drosophila Circadian Network Is a Seasonal Timer

Sensitivity of the human circadian pacemaker to nocturnal light: melatonin phase resetting and suppression

When brain clocks lose track of time: cause or consequence of neuropsychiatric disorders

Gene Model 129 (Gm129) Encodes a Novel Transcriptional Repressor That Modulates Circadian Gene Expression

Bidirectional communication between sleep and circadian rhythms and its implications for depression: Lessons from agomelatine

Sleep Patterns and Predictors of Disturbed Sleep in a Large Population of College Students

Molecular Clock Genes in Man and Lower Animals Possible Implications for Circadian Abnormalities in Depression

Saliva and serum samples were collected from eight healthy volunteers every two hours during a 26‐hour period. Melatonin concentrations were measured by radioimmunoassay after chloroform extraction using radioiodinated melatonin as a tracer. Five of the subjects had high serum melatonin levels at night (peak levels higher than 75 pg/ml); in three subjects the highest serum melatonin concentration was 20‐40 pg/ml. All subjects had low levels (<10 pg/ml) during the day. The correlations between salivary and serum levels were calculated. The regression line y =0.33×+ 3.7 pg/ml, r= 0.95, P <0.001, was obtained for all detectable value pairs (n= 73). The regression and correlation coefficients were almost equal for the peak values of melatonin and during the rising and descending phases of the secretion patterns. However, no significant correlation was found between low daytime salivary and serum concentrations when calculated separately. In the five high‐secretors the melatonin levels in saliva reflected reliably the changes in serum, but in the three low‐secretors the correlation between salivary and serum melatonin was not significant. The proportion of melatonin found in saliva decreased with increasing serum melatonin levels. Circadian rhythm parameters were estimated by single cosinor analysis. The acrophases did not differ significantly within a subject in the concomitant measurements of serum and salivary melatonin. The measurements of salivary melatonin levels seem valid for studies on melatonin rhythms, but the melatonin concentrations measured in saliva do not always consistently reflect the absolute concentrations in blood.

Linking “big” personality traits to anxiety, depressive, and substance use disorders: A meta-analysis.

The flinders sensitive line rats: A genetic animal model of depression

Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies

Circadian rhythms and sleep in bipolar disorder

The Physiology, Signaling, and Pharmacology of Dopamine Receptors

Circadian clock control of the cellular response to DNA damage

Circadian control of the immune system

Bipolar Disorder

Calibration of the Computer Science and Applications, Inc. accelerometer

Health-Related Quality of Life of Severely Obese Children and Adolescents

Interpersonal and social rhythm therapy: managing the chaos of bipolar disorder

Melatonin's Role in Vertebrate Orcadian Rhythms

Response of the melatonin cycle to phototherapy for Seasonal Affective Disorder

Design and synthesis of 4-arylpiperidinyl amide and N-arylpiperdin-3-yl-cyclopropane carboxamide derivatives as novel melatonin receptor ligands

Depression in the Elderly

An analysis of the “eveningness–morningness” dimension in “depressive” college students

Lithium in the Treatment of Mood Disorders

Major Depressive Disorder

Mental health of young people: a global public-health challenge

Biochemical Analysis of the Canonical Model for the Mammalian Circadian Clock

Pineal Melatonin: Cell Biology of Its Synthesis and of Its Physiological Interactions*

Constructive and unconstructive repetitive thought.

The Endophenotype Concept in Psychiatry: Etymology and Strategic Intentions

The Drosophila takeout Gene Is a Novel Molecular Link between Circadian Rhythms and Feeding Behavior

Why do many psychiatric disorders emerge during adolescence?

Vitamin D Deficiency in Children and Its Management: Review of Current Knowledge and Recommendations

The genetics of mammalian circadian order and disorder: implications for physiology and disease

Coordination of circadian timing in mammals

Risk Factors for Depression Among Elderly Community Subjects: A Systematic Review and Meta-Analysis

Endophenotypes in bipolar disorder†

Stress reactivity and coping in seasonal and nonseasonal depression

The Screen for Child Anxiety Related Emotional Disorders (SCARED): Scale Construction and Psychometric Characteristics

Switching From 'Unipolar' to Bipolar II

Why the Rat-1 Fibroblast Should Replace the SCN as the In Vitro Model of Choice

Kinases as drug targets in the treatment of bipolar disorder

Prophylaxis of Bipolar Affective Disorders

Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis

Cognitive-behavioral factors in seasonal affective disorder.

Cryptochrome: The Second Photoactive Pigment in the Eye and Its Role in Circadian Photoreception

Phototherapy of Seasonal Affective Disorder

A molecular mechanism for the effect of lithium on development.

Course and outcome of bipolar spectrum disorder in children and adolescents: A review of the existing literature

Treatment of Seasonal Affective Disorder with Light: Preliminary Australian Experience

The Wnt Signaling Pathway in Bipolar Disorder

Light therapy for non-seasonal depression

Practice Parameters for the Assessment and Treatment of Children and Adolescents With Depressive Disorders

Marked 24-h rest/activity rhythms are associated with better quality of life, better response, and longer survival in patients with metastatic colorectal cancer and good performance status.

Development of depression from preadolescence to young adulthood: Emerging gender differences in a 10-year longitudinal study.

Extraocular Circadian Phototransduction in Humans

Regulation of apoptosis by the circadian clock through NF-κB signaling

Central and Peripheral Circadian Clocks in Mammals

Seasonal Affective Disorders

About Sleep's Role in Memory

Electroconvulsive therapy. Pretreatment medical evaluation.

GSK-3: tricks of the trade for a multi-tasking kinase

Sleep Disruption: A Treatment for Depression and a Cause of Mania

Observations on the design and specification of a wrist-worn human activity monitoring system

Atypical depression: clinical aspects and noradrenergic function

Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions

Vitamin B ₂ -based blue-light photoreceptors in the retinohypothalamic tract as the photoactive pigments for setting the circadian clock in mammals

Transduction of psychosocial stress into the neurobiology of recurrent affective disorder

Role of Mouse Cryptochrome Blue-Light Photoreceptor in Circadian Photoresponses

Pertussis toxin-sensitive melatonin receptors negatively coupled to adenylate cyclase associated with cultured human and rat retinal pigment epithelial cells.

Practice Parameter for the Assessment and Treatment of Children and Adolescents With Depressive Disorders

Contrasts between symptoms of summer depression and winter depression

Towards Understanding the Mechanism of Action of Light in Seasonal Affective Disorder

Prevalence of seasonal difficulties in mood and behavior among Japanese civil servants

Rates of seasonal affective disorder in children and adolescents

Circadian rhythm disturbances in manic-depressive illness.

Sleep reduction as a final common pathway in the genesis of mania [published erratum appears in Am J Psychiatry 1987 Apr;144(4):542]

Phototherapy for seasonal affective disorder in Alaska

Melatonin in seasonal affective disorder and phototherapy.

Age at onset and number of psychotic symptoms in bipolar I and schizoaffective disorder

Rapid cycling affective disorder: contributing factors and treatment responses in 51 patients

Light therapy in patients with rapid cycling bipolar disorder: preliminary results.

Eye versus skin phototherapy of seasonal affective disorder

Winter seasonal affective disorder: a follow-up study of the first 59 patients of the National Institute of Mental Health Seasonal Studies Program

The phototherapy light visor: more to it than meets the eye

Antidepressant effects of sleep deprivation and phototherapy.

Seasonal affective disorder in children and adolescents

ECT in a depressed patient with adult onset diabetes mellitus

Morning versus midday phototherapy of seasonal affective disorder

Melatonin administration in insomnia.