Citation Impact
Citing Papers
Activity-Dependent Internalization of Smoothened Mediated by ß-Arrestin 2 and GRK2
2004 StandoutScienceNobel
Prospective identification of tumorigenic breast cancer cells
2003 Standout
Breast and Ovarian Cancer Risks Due to Inherited Mutations in BRCA1 and BRCA2
2003 StandoutScience
Missense mutations but not allelic variants alter the function of ATM by dominant interference in patients with breast cancer
2002
Case Detection, Diagnosis, and Treatment of Patients with Primary Aldosteronism: An Endocrine Society Clinical Practice Guideline
2008 Standout
Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma
2010 StandoutScience
Activating Smoothened mutations in sporadic basal-cell carcinoma
1998 StandoutNature
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
2008 StandoutNature
The DNA-damage response in human biology and disease
2009 StandoutNature
Base-excision repair of oxidative DNA damage
2007 StandoutNature
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
2005 StandoutNature
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein
1999 StandoutNature
IDH1andIDH2Mutations in Gliomas
2009 Standout
Inducible Nitric-oxide Synthase and Nitric Oxide Production in Human Fetal Astrocytes and Microglia
1997 StandoutNobel
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
2003 StandoutNature
Update in the epidemiology of Parkinson's disease
2008
Glucocorticoid-Remediable Aldosteronism
2003
Loss of poly(ADP-ribose) polymerase-1 causes increased tumour latency in p53-deficient mice
2001
The patched signaling pathway in tumorigenesis and development: lessons from animal models
1999
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
2003 StandoutNobel
A novel human DNA glycosylase that removes oxidative DNA damage and is homologous to Escherichia coli endonuclease VIII
2002
Hedgehog and Patched in Neural Development and Disease
1998
NITRIC OXIDE PRODUCTION IN CELLS DERIVED FROM THE HUMAN JOINT
1996
Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma
2005 StandoutNature
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Genetic Disorders Associated with Cancer Predisposition and Genomic Instability
1999
Cell-cycle checkpoints and cancer
2004 StandoutNature
Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of β-catenin, and enhanced tumor cell invasion
2003
The Role of the p53 Tumor Suppressor Gene in Squamous Cell Carcinoma of the Head and Neck
1993
Hedgehog signalling in the mouse requires intraflagellar transport proteins
2003 StandoutNature
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
2005 StandoutNature
Genetic instabilities in human cancers
1998 StandoutNature
Nbs1 promotes ATM dependent phosphorylation events including those required for G1/S arrest
2002
Autophagy fights disease through cellular self-digestion
2008 StandoutNature
ATM: from gene to function
1998
ATM and related protein kinases: safeguarding genome integrity
2003 Standout
Inactivation of Conserved C. elegans Genes Engages Pathogen- and Xenobiotic-Associated Defenses
2012 StandoutNobel
ATM Mutations in Sporadic Lymphoid Tumours
2002
Patched acts catalytically to suppress the activity of Smoothened
2002 Nature
The hedgehog signaling network
2003
The Hedgehog and Wnt signalling pathways in cancer
2001 StandoutNature
Cancer Risk and the ATM Gene: a Continuing Debate
2000
Medulloblastoma Growth Inhibition by Hedgehog Pathway Blockade
2002 StandoutScience
Evidence That the Penetrance of Mutations at the RP11 Locus Causing Dominant Retinitis Pigmentosa Is Influenced by a Gene Linked to the Homologous RP11 Allele
1997
Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent Phosphorylation of Chk1 on Ser-317 in Response to Ionizing Radiation
2003
Bypassing cellular EGF receptor dependence through epithelial-to-mesenchymal-like transitions
2008
Autophagy: Renovation of Cells and Tissues
2011 Standout
Parkinson's disease
2009 Standout
A DNA damage checkpoint response in telomere-initiated senescence
2003 StandoutNature
Immunogenicity of induced pluripotent stem cells
2011 StandoutNature
Comprehensive analysis of oncogenic effects of PIK3CA mutations in human mammary epithelial cells
2007
Primary aldosteronism: renaissance of a syndrome
2007
Cloning and Genomic Organization of Beclin 1, a Candidate Tumor Suppressor Gene on Chromosome 17q21
1999
Induction of autophagy and inhibition of tumorigenesis by beclin 1
1999 StandoutNature
Universal and rapid salt-extraction of high quality genomic DNA for PCR- based techniques
1997 Standout
Autophagy in the Pathogenesis of Disease
2008 Standout
Cause and Consequences of Genetic and Epigenetic Alterations in Human Cancer
2008
New players and puzzles in the Hedgehog signaling pathway
1998
Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine
2000 StandoutNature
C. elegans patched-3 is an essential gene implicated in osmoregulation and requiring an intact permease transporter domain
2011
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
Transducing Hedgehog: the story so far
1998
The DNA damage response: putting checkpoints in perspective
2000 StandoutNature
Severity of Hypertension in Familial Hyperaldosteronism Type I: Relationship to Gender and Degree of Biochemical Disturbance1
2000
The DNA Double-Strand Break Repair Gene hMRE11 Is Mutated in Individuals with an Ataxia-Telangiectasia-like Disorder
1999
The role of autophagy during the early neonatal starvation period
2004 StandoutNatureNobel
The enigma of endonuclease VIII
2003
Recent advances in breast cancer biology
1999
The hedgehog pathway and basal cell carcinomas
2001
The TRA-1A Sex Determination Protein of C. elegans Regulates Sexually Dimorphic Cell Deaths by Repressing the egl-1 Cell Death Activator Gene
1999 StandoutNobel
Mutations in SUFU predispose to medulloblastoma
2002 Standout
Cancer Risk in ATM Heterozygotes: A Model of Phenotypic and Mechanistic Differences between Missense and Truncating Mutations
1999
Frequent Activating Mutations of PIK3CA in Ovarian Clear Cell Carcinoma
2009
Improving survival from sudden cardiac arrest: the "chain of survival" concept. A statement for health professionals from the Advanced Cardiac Life Support Subcommittee and the Emergency Cardiac Care Committee, American Heart Association.
1991 Standout
Karyotypic complexity of the NCI-60 drug-screening panel.
2003
Linkage localization of X-linked Charcot-Marie-Tooth disease.
1993
Ataxia telangiectasia mutated (Atm) is not required for telomerase-mediated elongation of short telomeres
2006 StandoutNobel
Patched1 Regulates Hedgehog Signaling at the Primary Cilium
2007 StandoutScience
Spectrum of ATM gene mutations in a hospital-based series of unselected breast cancer patients.
2001
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Hedgehog Signaling and Human Disease
2002
Refined genetic mapping of X-linked Charcot-Marie-Tooth neuropathy.
1994
Use of defibrillators by general practitioners.
1988
Digital karyotyping identifies thymidylate synthase amplification as a mechanism of resistance to 5-fluorouracil in metastatic colorectal cancer patients
2004
The Management of Primary Aldosteronism: Case Detection, Diagnosis, and Treatment: An Endocrine Society Clinical Practice Guideline
2016 Standout
Role for ATM in DNA damage-induced phosphorylation of BRCA1.
2000
Mutations of the PATCHED gene in several types of sporadic extracutaneous tumors.
1997
Medulloblastomas of the desmoplastic variant carry mutations of the human homologue of Drosophila patched.
1997
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
2004 StandoutNobel
Connexin Mutations in X-Linked Charcot-Marie-Tooth Disease
1993 StandoutScience
Prevalence and Characteristics of Familial Hyperaldosteronism
2011
Molecular phenotyping for analyzing subtle genetic effects in mice: Application to an angiotensinogen gene titration
2002 StandoutNobel
Autophagy in Health and Disease: A Double-Edged Sword
2004 StandoutScience
Works of N E Haites being referenced
Colorectal cancer genomics: evidence for multiple genotypes which influence survival
2001
Epidermal growth factor (EGF) Increases the in vitro invasion, motility and adhesion interactions of the primary renal carcinoma cell line, A704
1996
Environmental risk factors for Parkinson’s disease and parkinsonism: the Geoparkinson study
2007
Linkage in a family with X‐linked Charcot‐Marie‐Tooth disease
1989
Induction of Nitric Oxide Synthase in Human Mesangial Cells
1993
Is random screening of value in detecting glucocorticoid-remediable aldosteronism within a hypertensive population?
2001
ATM Mutations and Phenotypes in Ataxia-Telangiectasia Families in the British Isles: Expression of Mutant ATM and the Risk of Leukemia, Lymphoma, and Breast Cancer
1998
Comparative genomic hybridization and chromosomal instability in solid tumours
1999
p53 mutation is a common genetic event in ovarian carcinoma.
1993
Most germ-line mutations in the nevoid basal cell carcinoma syndrome lead to a premature termination of the PATCHED protein, and no genotype-phenotype correlations are evident.
1997
Linkage of a medium sized Scottish autosomal dominant retinitis pigmentosa family to chromosome 7q.
1996
Repeated freezing and thawing of peripheral blood and DNA in suspension: effects on DNA yield and integrity.
1990
Comparative genomic hybridization analysis of chromosomal alterations induced by the development of resistance to thymidylate synthase inhibitors.
1998
Early loss of heterozygosity on 17q in ovarian cancer. The Abe Ovarian Cancer Genetics Group.
1992
Variation of phenotype in patients with glucocorticoid remediable aldosteronism.
1996
One thousand heart attacks in Grampian: the place of cardiopulmonary resuscitation in general practice.
1987