Citation Impact
Citing Papers
Membrane-tethered mucin-like polypeptides sterically inhibit binding and slow fusion kinetics of influenza A virus
2020 StandoutNobel
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
ZBTB1 is a determinant of lymphoid development
2011 StandoutNobel
Inverting family GH156 sialidases define an unusual catalytic motif for glycosidase action
2019 StandoutNobel
Conversion of monomeric protein L to an obligate dimer by computational protein design
2001 StandoutNobel
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
COPII-Coated Vesicle Formation Reconstituted with Purified Coat Proteins and Chemically Defined Liposomes
1998 StandoutNobel
Cigarette smoke-mediated inflammatory and oxidative responses are strain-dependent in mice
2008
Cloning and Characterization of a Wortmannin-sensitive Human Phosphatidylinositol 4-Kinase
1997
Multiple Elements Jointly Determine Inhibitor Selectivity of Cyclic Nucleotide Phosphodiesterases 4 and 7
2005
Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase
1995
Oncogenic kinase signalling
2001 StandoutNature
Cyclic nucleotide phosphodiesterase (PDE) superfamily: A new target for the development of specific therapeutic agents
2005 Standout
Cyclic Nucleotide Phosphodiesterases: Molecular Regulation to Clinical Use
2006 Standout
DNA Damage-Induced Phosphorylation of p53 Alleviates Inhibition by MDM2
1997 Standout
The activation of phosphatidylinositol 3-kinase by Ras
1994
Respiratory Tract Mucin Genes and Mucin Glycoproteins in Health and Disease
2005
Glycosylation in Cellular Mechanisms of Health and Disease
2006 Standout
Insulin Stimulates Hypoxia-inducible Factor 1 through a Phosphatidylinositol 3-Kinase/Target of Rapamycin-dependent Signaling Pathway
2002 StandoutNobel
Hematopoiesis: An Evolving Paradigm for Stem Cell Biology
2008 Standout
Purification and Biochemical Characterization of a Mammalian Phosphatidylinositol 3,4,5-Trisphosphate 5-Phosphatase
1995
High Resolution Crystal Structures of Siglec-7
2003
Differential Roles for Sox15 and Sox2 in Transcriptional Control in Mouse Embryonic Stem Cells
2005 StandoutNobel
Analysis of the Catalytic Domain of Phosphatidylinositol 4-Kinase Type II
2002 StandoutNobel
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
Head‐to‐Tail Peptide Cyclodimerization by Copper‐Catalyzed Azide–Alkyne Cycloaddition
2005
Understanding the pathogenesis of allergic asthma using mouse models
2001
Synaptojanin Is the Major Constitutively Active Phosphatidylinositol-3,4,5-trisphosphate 5-Phosphatase in Rodent Brain
1997
The AtVAM3 Encodes a Syntaxin-related Molecule Implicated in the Vacuolar Assembly in Arabidopsis thaliana
1997 StandoutNobel
The Atg18-Atg2 Complex Is Recruited to Autophagic Membranes via Phosphatidylinositol 3-Phosphate and Exerts an Essential Function
2008 StandoutNobel
Insulin Regulation of Phosphoenolpyruvate Carboxykinase Gene Expression Does Not Require Activation of the Ras/Mitogen-activated Protein Kinase Signaling Pathway
1996
Phosphatidylinositol 3-Kinase, but Not p70/p85 Ribosomal S6 Protein Kinase, Is Required for the Regulation of Phosphoenolpyruvate Carboxykinase (PEPCK) Gene Expression by Insulin
1995
Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway
1997
Wortmannin and Its Structural Analogue Demethoxyviridin Inhibit Stimulated Phospholipase A2 Activity in Swiss 3T3 Cells
1995
Synthetic Multivalent Ligands as Probes of Signal Transduction
2006
Survey of the year 2003 commercial optical biosensor literature
2004
Sox18 induces development of the lymphatic vasculature in mice
2008 StandoutNature
Airway Mucus Function and Dysfunction
2010 Standout
The Transcriptional Regulation of B Cell Lineage Commitment
2007
Creation of a biologically active interleukin-5 monomer
1996 Nature
Discovery of BRL 50481 [3-(N,N-dimethylsulfonamido)-4-methyl-nitrobenzene], a Selective Inhibitor of Phosphodiesterase 7: In Vitro Studies in Human Monocytes, Lung Macrophages, and CD8+ T-Lymphocytes
2004
Synthesis and Microcontact Printing of Dual End‐Functionalized Mucin‐like Glycopolymers for Microarray Applications
2009 StandoutNobel
Wortmannin Inhibits Mitogen-activated Protein Kinase Activation by Platelet-activating Factor through a Mechanism Independent of p85/p110-type Phosphatidylinositol 3-Kinase
1996
Glycan Array Screening Reveals a Candidate Ligand for Siglec-8*
2004
Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation
2013 StandoutNature
Multifarious roles of sialic acids in immunity
2012
Electrochemical Intramolecular CH Amination: Synthesis of Benzoxazoles and Benzothiazoles
2015
β-Arrestin-2 regulates the development of allergic asthma
2003 StandoutNobel
Survey of the year 2001 commercial optical biosensor literature
2002
Phosphatidylinositol 3-Kinase Is an Early Intermediate in the Gβγ-mediated Mitogen-activated Protein Kinase Signaling Pathway
1996 StandoutNobel
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Developmentally Regulated Alternative Splicing in a Novel Synaptojanin
1998 StandoutNobel
Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
2013 Standout
Can a Ketone Be More Reactive than an Aldehyde? Catalytic Asymmetric Synthesis of Substituted Tetrahydrofurans
2018 StandoutNobel
Electrochemical intramolecular dehydrogenative C–S bond formation for the synthesis of benzothiazoles
2017
Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates primary and secondary peptide-specific CD4+T cell responses
1999 StandoutNobel
The Immunological Synapse: A Molecular Machine Controlling T Cell Activation
1999 StandoutScience
Density Variant Glycan Microarray for Evaluating Cross-Linking of Mucin-like Glycoconjugates by Lectins
2012 StandoutNobel
Synthesis of Glycopolymers for Microarray Applications via Ligation of Reducing Sugars to a Poly(acryloyl hydrazide) Scaffold
2010 StandoutNobel
Palladium-Catalyzed Synthesis of 2-Substituted Benzothiazoles via a C−H Functionalization/Intramolecular C−S Bond Formation Process
2008
Role of phosphatidylinositol 3-OH-kinase activity in the inhibition of apoptosis in haemopoietic cells: phosphatidylinositol 3-OH-kinase inhibitors reveal a difference in signalling between interleukin-3 and granulocyte-macrophage colony stimulating factor
1995
Different sensitivity to wortmannin of two vacuolar sorting signals indicates the presence of distinct sorting machineries in tobacco cells.
1995
Matching SOX: partner proteins and co-factors of the SOX family of transcriptional regulators
2002
Structural and Co-conformational Effects of Alkyne-Derived Subunits in Charged Donor−Acceptor [2]Catenanes
2007 StandoutNobel
A human phosphatidylinositol 3-kinase complex related to the yeast Vps34p-Vps15p protein sorting system.
1995
Membrane-permeant Esters of Phosphatidylinositol 3,4,5-Trisphosphate
1998 StandoutNobel
Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization
2009
Integrin Signaling
1999 StandoutScience
Synthetic Organic Electrochemical Methods Since 2000: On the Verge of a Renaissance
2017 Standout
Enantioselective Copper-Catalyzed Alkynylation of Benzopyranyl Oxocarbenium Ions
2015
The Essential Roles of Chemistry in High-Throughput Screening Triage
2014
Transcriptional Control of Early B Cell Development
2004
Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery
1997 Standout
Precision glycocalyx editing as a strategy for cancer immunotherapy
2016 StandoutNobel
β-Arrestin-2 regulates the development of allergic asthma
2003 StandoutNobel
Siglec-G Deficiency Leads to Autoimmunity in Aging C57BL/6 Mice
2015
Aquaglyceroporin AQP9: Solute permeation and metabolic control of expression in liver
2003 StandoutNobel
Phosphatidylinositol 3-Kinase Is Required for Integrin-Stimulated AKT and Raf-1/Mitogen-Activated Protein Kinase Pathway Activation
1997
Surface Plasmon Resonance Sensors for Detection of Chemical and Biological Species
2008 Standout
Vps34p required for yeast vacuolar protein sorting is a multiple specificity kinase that exhibits both protein kinase and phosphatidylinositol-specific PI 3-kinase activities.
1994
Asymmetric Catalysis via Cyclic, Aliphatic Oxocarbenium Ions
2017 StandoutNobel
TCR- and CD28-Mediated Recruitment of Phosphodiesterase 4 to Lipid Rafts Potentiates TCR Signaling
2004
Visible Light Photoredox Catalysis with Transition Metal Complexes: Applications in Organic Synthesis
2013 Standout
Wortmannin inhibits mitogen-activated protein kinase activation induced by platelet-activating factor in guinea pig neutrophils.
1994
Enhanced Phosphorylation of p53 by ATM in Response to DNA Damage
1998 StandoutScience
Chemistry: Chemical con artists foil drug discovery
2014 StandoutNature
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
A Receptor/Cytoskeletal Movement Triggered by Costimulation During T Cell Activation
1998 Science
Two Distinct Vps34 Phosphatidylinositol 3–Kinase Complexes Function in Autophagy and Carboxypeptidase Y Sorting inSaccharomyces cerevisiae
2001 StandoutNobel
Ligation of Siglec-8: a selective mechanism for induction of human eosinophil apoptosis
2003
Wortmannin Inactivates Phosphoinositide 3-Kinase by Covalent Modification of Lys-802, a Residue Involved in the Phosphate Transfer Reaction
1996
Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions
2010 Standout
Wortmannin causes mistargeting of procathepsin D. evidence for the involvement of a phosphatidylinositol 3-kinase in vesicular transport to lysosomes.
1995
Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design
2011 Standout
Works of Murray McKinnon being referenced
Identification of Key Charged Residues of Human Interleukin-5 in Receptor Binding and Cellular Activation
1995
A comparison of demethoxyviridin and wortmannin as inhibitors of phosphatidylinositol 3‐kinase
1994
Utilization of a nitrogen–sulfur nonbonding interaction in the design of new 2-aminothiazol-5-yl-pyrimidines as p38α MAP kinase inhibitors
2010
Synthesis, initial SAR and biological evaluation of 1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-4-amine derived inhibitors of IκB kinase
2009
A new siglec family member, siglec‐10, is expressed in cells of the immune system and has signaling properties similar to CD33
2001
Benzothiazole based inhibitors of p38α MAP kinase
2008
A MURINE MODEL OF CIGARETTE SMOKE-INDUCED PULMONARY INFLAMMATION USING INTRANASALLY ADMINISTERED SMOKE-CONDITIONED MEDIUM
2002
A Collaborative Hit-to-Lead Investigation Leveraging Medicinal Chemistry Expertise with High Throughput Library Design, Synthesis and Purification Capabilities
2006
Phosphodiesterase 7A-Deficient Mice Have Functional T Cells
2003
An Interleukin 5 Mutant Distinguishes between Two Functional Responses in Human Eosinophils
1997
A potent dimeric peptide antagonist of interleukin-5 that binds two interleukin-5 receptor α chains
2000
Cytokine-Specific Transcriptional Regulation Through an IL-5Rα Interacting Protein
2001 Science