Citation Impact
Citing Papers
A conserved MutS homolog connector domain interface interacts with MutL homologs
2009
MutL traps MutS at a DNA mismatch
2015 StandoutNobel
C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion
2014 StandoutNobel
Visualization of the movement of single histidine kinase molecules in live Caulobacter cells
2004 StandoutNobel
Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation
2013 StandoutScience
A possible mechanism for exonuclease 1-independent eukaryotic mismatch repair
2009 StandoutNobel
Protein roadblocks and helix discontinuities are barriers to the initiation of mismatch repair
2007 StandoutNobel
The Interaction of DNA Mismatch Repair Proteins with Human Exonuclease I
2001
Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism
2009 StandoutNobel
Genetic manipulation of Patescibacteria provides mechanistic insights into microbial dark matter and the epibiotic lifestyle
2023 StandoutNobel
ATP Increases the Affinity between MutS ATPase Domains
2004
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
2014 StandoutNatureNobel
Mutations within the hMLH1 and hPMS2 Subunits of the Human MutLα Mismatch Repair Factor Affect Its ATPase Activity, but Not Its Ability to Interact with hMutSα
2002
PAXX promotes KU accumulation at DNA breaks and is essential for end-joining in XLF-deficient mice
2017
The DNA-damage response in human biology and disease
2009 StandoutNature
Mismatch Repair in Human Nuclear Extracts
2003
Distinct MutS DNA-binding Modes That Are Differentially Modulated by ATP Binding and Hydrolysis
2001 StandoutNobel
(CAG)n-hairpin DNA binds to Msh2–Msh3 and changes properties of mismatch recognition
2005
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
2016 StandoutNature
Escherichia coli MutL Loads DNA Helicase II onto DNA
2000
Characteristics of SARS-CoV-2 and COVID-19
2020 Standout
The β Sliding Clamp Binds to Multiple Sites within MutL and MutS
2006 StandoutNobel
HNPCC mutations in the human DNA mismatch repair gene hMLH1 influence assembly of hMutLα and hMLH1–hEXO1 complexes
2001
Single molecule studies of DNA mismatch repair
2014
RecA-like motor ATPases—lessons from structures
2004
Defining interactions between DNA-PK and ligase IV/XRCC4
2002
Differential and Simultaneous Adenosine Di- and Triphosphate Binding by MutS
2003 StandoutNobel
XLF Interacts with the XRCC4-DNA Ligase IV Complex to Promote DNA Nonhomologous End-Joining
2006
Hydrolytically Deficient MutS E694A Is Defective in the MutL-dependent Activation of MutH and in the Mismatch-dependent Assembly of the MutS · MutL · Heteroduplex Complex
2003 StandoutNobel
Reconstitution of 5′-Directed Human Mismatch Repair in a Purified System
2005
Structure of Unliganded GRP94, the Endoplasmic Reticulum Hsp90
2005
Structural Analysis of E. coli hsp90 Reveals Dramatic Nucleotide-Dependent Conformational Rearrangements
2006
Direct Visualization of Asymmetric Adenine Nucleotide-Induced Conformational Changes in MutLα
2008 StandoutNobel
Structure and function of the N-terminal 40 kDa fragment of human PMS2: a monomeric GHL ATPase
2001
DNA mismatch repair: MutS structures bound to mismatches
2001
N-terminus of hMLH1 confers interaction of hMutL and hMutL with hMutS
2003
Differential ATP Binding and Intrinsic ATP Hydrolysis by Amino-terminal Domains of the Yeast Mlh1 and Pms1 Proteins
2002
Structures of Escherichia coli DNA mismatch repair enzyme MutS in complex with different mismatches: a common recognition mode for diverse substrates
2003
Disruption of the helix-u-turn-helix motif of MutS protein: loss of subunit dimerization, mismatch binding and ATP hydrolysis
2001
Structural Biology of Rad50 ATPase
2000
Modes of interaction among yeast Nej1, Lif1 and Dnl4 proteins and comparison to human XLF, XRCC4 and Lig4
2007
Structural Dissection of ATP Turnover in the Prototypical GHL ATPase TopoVI
2005
Cernunnos Interacts with the XRCC4·DNA-ligase IV Complex and Is Homologous to the Yeast Nonhomologous End-joining Factor Nej1
2006
DNA Mismatch Repair in Eukaryotes and Bacteria
2010
Mechanism and regulation of human non-homologous DNA end-joining
2003
Structure of the topoisomerase VI-B subunit: implications for type II topoisomerase mechanism and evolution
2002
DNA mismatch repair and mutation avoidance pathways
2002
Endonucleolytic Function of MutLα in Human Mismatch Repair
2006 StandoutNobel
Mismatch repair proteins: key regulators of genetic recombination
2004
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
2017 StandoutNature
Dominant Saccharomyces cerevisiae msh6 Mutations Cause Increased Mispair Binding and Decreased Dissociation from Mispairs by Msh2-Msh6 in the Presence of ATP
2002
Contribution of Human Mlh1 and Pms2 ATPase Activities to DNA Mismatch Repair
2002
The multifaceted mismatch-repair system
2006
MSH2 ATPase Domain Mutation Affects CTG•CAG Repeat Instability in Transgenic Mice
2009
Crystal structure of an Hsp90–nucleotide–p23/Sba1 closed chaperone complex
2006 Nature
Retraction of DNA-bound type IV competence pili initiates DNA uptake during natural transformation in Vibrio cholerae
2018
Mismatch Repair in Human Nuclear Extracts
2002
Ligand-induced Conformational Shift in the N-terminal Domain of GRP94, an Hsp90 Chaperone
2004
GHKL, an emergent ATPase/kinase superfamily
2000
Cryo-EM structures of fungal and metazoan mitochondrial calcium uniporters
2018 Nature
Formation of a DNA Mismatch Repair Complex Mediated by ATP
2003
The antibiotic resistome: what's new?
2014
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
Signaling from DNA mispairs to mismatch‐repair excision sites despite intervening blockades
2004
Conformational changes in the G protein Gs induced by the β2 adrenergic receptor
2011 StandoutNatureNobel
Molecular chaperones in protein folding and proteostasis
2011 StandoutNature
The Coordinated Functions of the E. coli MutS and MutL Proteins in Mismatch Repair
2003
Structure and function of mismatch repair proteins
2000
Interaction of Escherichia coli MutS and MutL at a DNA Mismatch
2001
Protein fold recognition using sequence profiles and its application in structural genomics
2000
Structure of the MutL C‐terminal domain: a model of intact MutL and its roles in mismatch repair
2004
Lymphocyte-Specific Compensation for XLF/Cernunnos End-Joining Functions in V(D)J Recombination
2008
The mechanism of mismatch repair and the functional analysis of mismatch repair defects in Lynch syndrome
2013
Steady-state Regulation of the Human DNA Mismatch Repair System
2000
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ
2007
Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA
2000 Nature
Signal transduction: Gyrating protein kinases
1999
Large conformational changes in MutS during DNA scanning, mismatch recognition and repair signalling
2012
DNA Mismatch Repair
2000
DNA-PK: A dynamic enzyme in a versatile DSB repair pathway
2014
Stoichiometry of MutS and MutL at unrepaired mismatches in vivo suggests a mechanism of repair
2012
Functional interactions and signaling properties of mammalian DNA mismatch repair proteins
2001
Differential Specificities and Simultaneous Occupancy of Human MutSα Nucleotide Binding Sites
2004 StandoutNobel
Xrcc4 physically links DNA end processing by polynucleotide kinase to DNA ligation by DNA ligase IV
2004
CASK Functions as a Mg2+-Independent Neurexin Kinase
2008 StandoutNobel
Mapping Protein-Protein Interactions between MutL and MutH by Cross-linking
2004
Separation of mutation avoidance and antirecombination functions in an Escherichia coli mutS mutant
2005
DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis
2020 StandoutNatureNobel
Analysis of yeast MSH2-MSH6 suggests that the initiation of mismatch repair can be separated into discrete steps
2000
Crystal structure of an Xrcc4-DNA ligase IV complex.
2001
A Biochemically Defined System for Mammalian Nonhomologous DNA End Joining
2004
DNA Repair in Mammalian Cells
2009
Drug Targets in Mycobacterial Sulfur Metabolism
2007
Mismatch Repair in Human Nuclear Extracts
2002
High affinity cooperative DNA binding by the yeast Mlh1-Pms1 heterodimer 1 1Edited by M. Belfort
2001
Phosphorylation and Regulation of DNA Ligase IV Stability by DNA-dependent Protein Kinase
2004
Implication of DNA Polymerase λ in Alignment-based Gap Filling for Nonhomologous DNA End Joining in Human Nuclear Extracts
2003
The MutL ATPase Is Required for Mismatch Repair
2000 StandoutNobel
Mechanisms and functions of DNA mismatch repair
2007
Chapter 2 DNA-PK
2008
DNA mismatch repair: Molecular mechanism, cancer, and ageing
2008
The crystal structure of DNA mismatch repair protein MutS binding to a G·T mismatch
2000 Nature
Nucleotide binding by the histidine kinase CheA.
2001
Mammalian DNA mismatch repair protects cells from UVB-induced DNA damage by facilitating apoptosis and p53 activation
2003
Analysis of Interactions Between Mismatch Repair Initiation Factors and the Replication Processivity Factor PCNA
2005
DNA Chain Length Dependence of Formation and Dynamics of hMutSα·hMutLα·Heteroduplex Complexes
2001 StandoutNobel
Antibacterial drug discovery in the resistance era
2016 StandoutNature
Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System
2015 StandoutNobel
Cryo-EM structure of the homohexameric T3SS ATPase-central stalk complex reveals rotary ATPase-like asymmetry
2019
The alternating ATPase domains of MutS control DNA mismatch repair
2003
Simple yet functional phosphate-loop proteins
2018 StandoutNobel
PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair
2010 StandoutNobel
Sulfatase-activated fluorophores for rapid discrimination of mycobacterial species and strains
2013 StandoutNobel
Mammalian DNA Mismatch Repair
1999
Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining
2009
Magnesium in Man: Implications for Health and Disease
2014 Standout
DNA MISMATCH REPAIR AND GENETIC INSTABILITY
2000
DNA MISMATCH REPAIR
2005
Analysis of the Quaternary Structure of the MutL C-terminal Domain
2005
DNA bending and unbending by MutS govern mismatch recognition and specificity
2003
Single-molecule imaging reveals target-search mechanisms during DNA mismatch repair
2012
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
In vivo requirement for RecJ, ExoVII, ExoI, and ExoX in methyl-directed mismatch repair
2001 StandoutNobel
DNA Mismatch Repair: Molecular Mechanisms and Biological Function
2003
Two-Component Signal Transduction
2000 Standout
Molecular Chaperones in the Cytosol: from Nascent Chain to Folded Protein
2002 StandoutScience
PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance
2010 StandoutNobel
Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals
2022 StandoutScienceNobel
The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway
2010 Standout
Monovalent cation dependence and preference of GHKL ATPases and kinases1
2003
Hsp90
2001
exo1-Dependent Mutator Mutations: Model System for Studying Functional Interactions in Mismatch Repair
2001
Functional Studies on the Candidate ATPase Domains of Saccharomyces cerevisiae MutLα
2000
Computational design of mechanically coupled axle-rotor protein assemblies
2022 StandoutScienceNobel
Functional specificity of MutL homologs in yeast: Evidence for three Mlh1-based heterocomplexes with distinct roles during meiosis in recombination and mismatch correction
1999
Protein Structure Prediction and Structural Genomics
2001 StandoutScienceNobel
Mismatch Recognition-Coupled Stabilization of Msh2-Msh6 in an ATP-Bound State at the Initiation of DNA Repair
2003
Simultaneous precise editing of multiple genes in human cells
2019 StandoutNobel
V(D)J Recombination: RAG Proteins, Repair Factors, and Regulation
2002
Origins and Evolution of Antibiotic Resistance
2010 Standout
DNA Ligases: Structure, Reaction Mechanism, and Function
2006
Extrahelical (CAG)/(CTG) triplet repeat elements support proliferating cell nuclear antigen loading and MutLα endonuclease activation
2013 StandoutNobel
High rate of CAD gene amplification in human cells deficient in MLH1 or MSH6
2001 StandoutNobel
Slow Conformational Changes in MutS and DNA Direct Ordered Transitions between Mismatch Search, Recognition and Signaling of DNA Repair
2013
Asymmetric ATP Binding and Hydrolysis Activity of the Thermus aquaticus MutS Dimer Is Key to Modulation of Its Interactions with Mismatched DNA
2004
MutS/MutL crystal structure reveals that the MutS sliding clamp loads MutL onto DNA
2015
Structural insights into TRPM8 inhibition and desensitization
2019 StandoutScienceNobel
Nonhomologous End Joining in Yeast
2005
Works of M.S. Junop being referenced
Pseudomonas aeruginosa Minor Pilins Prime Type IVa Pilus Assembly and Promote Surface Display of the PilY1 Adhesin
2014
Identification of the Docking Site between a Type III Secretion System ATPase and a Chaperone for Effector Cargo
2014
Composite Active Site of an ABC ATPase
2001
Transformation of MutL by ATP Binding and Hydrolysis
1999
DNA Mismatch Repair: From Structure to Mechanism
2000
Structure and Mechanism of the Lincosamide Antibiotic Adenylyltransferase LinB
2009
In vitro and in vivo studies of MutS, MutL and MutH mutants: correlation of mismatch repair and DNA recombination
2003
Crystal structure of the Xrcc4 DNA repair protein and implications for end joining
2000
A human XRCC4–XLF complex bridges DNA
2012
Structural Insights into Mitochondrial Calcium Uniporter Regulation by Divalent Cations
2016
Tetramerization and DNA Ligase IV Interaction of the DNA Double-strand Break Repair Protein XRCC4 are Mutually Exclusive
2003
Crystal Structure of Human XLF: A Twist in Nonhomologous DNA End-Joining
2007
Unraveling the Complexities of DNA-Dependent Protein Kinase Autophosphorylation
2014
Broad and Differential Animal Angiotensin-Converting Enzyme 2 Receptor Usage by SARS-CoV-2
2020
Rifamycin antibiotic resistance by ADP-ribosylation: Structure and diversity of Arr
2008
Inhibitors of Bacterial Cystathionine β-Lyase: Leads for New Antimicrobial Agents and Probes of Enzyme Structure and Function
2007