Citation Impact
Citing Papers
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion
2020 StandoutNobel
Hallucinating symmetric protein assemblies
2022 StandoutScienceNobel
Diversity oriented clicking delivers β-substituted alkenyl sulfonyl fluorides as covalent human neutrophil elastase inhibitors
2022 StandoutNobel
Computational Stabilization of a Non‐Heme Iron Enzyme Enables Efficient Evolution of New Function
2024 StandoutNobel
Computation and Functional Studies Provide a Model for the Structure of the Zinc Transporter hZIP4
2015 StandoutNobel
Improving physical realism, stereochemistry, and side‐chain accuracy in homology modeling: Four approaches that performed well in CASP8
2009 StandoutNobel
Divergence and Convergence in Enzyme Evolution: Parallel Evolution of Paraoxonases from Quorum-quenching Lactonases
2011
From Ru-bda to Ru-bds: a step forward to highly efficient molecular water oxidation electrocatalysts under acidic and neutral conditions
2021
Discovery of archaeal fusexins homologous to eukaryotic HAP2/GCS1 gamete fusion proteins
2022 StandoutNobel
Progress in the development of enzyme-based nerve agent bioscavengers
2013
Efficacy of the rePON1 mutant IIG1 to prevent cyclosarin toxicity in vivo and to detoxify structurally different nerve agents in vitro
2014
Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity
2020 StandoutNobel
Improved molecular replacement by density- and energy-guided protein structure optimization
2011 StandoutNatureNobel
Catalytic bioscavengers in nerve agent poisoning: A promising approach?
2015
CAD‐score: A new contact area difference‐based function for evaluation of protein structural models
2012
Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis
2012 StandoutNobel
High‐Throughput Screening for Terpene‐Synthase‐Cyclization Activity and Directed Evolution of a Terpene Synthase
2013 StandoutNobel
CASP8 results in context of previous experiments
2009
Methods for the directed evolution of proteins
2015
Computational Enzyme Design
2013 StandoutNobel
Single treatment of VX poisoned guinea pigs with the phosphotriesterase mutant C23AL: Intraosseous versus intravenous injection
2016
SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information
2014 Standout
The other 90% of the protein: Assessment beyond the Cαs for CASP8 template‐based and high‐accuracy models
2009
Recognizing Protein-Ligand Binding Sites by Global Structural Alignment and Local Geometry Refinement
2012
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
Directed enzyme evolution: beyond the low-hanging fruit
2012
Role of the Biomolecular Energy Gap in Protein Design, Structure, and Evolution
2012 StandoutNobel
Automated protein structure modeling in CASP9 by I‐TASSER pipeline combined with QUARK‐based ab initio folding and FG‐MD‐based structure refinement
2011
Principles for designing ideal protein structures
2012 StandoutNatureNobel
I-TASSER server: new development for protein structure and function predictions
2015 Standout
Expanding the Enzyme Universe: Accessing Non‐Natural Reactions by Mechanism‐Guided Directed Evolution
2015 StandoutNobel
The trRosetta server for fast and accurate protein structure prediction
2021 StandoutNobel
Genetically programmed chiral organoborane synthesis
2017 StandoutNatureNobel
In vitro detoxification of cyclosarin in human blood pre-incubated ex vivo with recombinant serum paraoxonases
2011
The dual role of fragments in fragment‐assembly methods for de novo protein structure prediction
2011 StandoutNobel
Ab initio protein structure assembly using continuous structure fragments and optimized knowledge‐based force field
2012
The coming of age of de novo protein design
2016 StandoutNatureNobel
Conformational changes in the G protein Gs induced by the β2 adrenergic receptor
2011 StandoutNatureNobel
Enzyme engineering: reaching the maximal catalytic efficiency peak
2017
Current and emerging strategies for organophosphate decontamination: special focus on hyperstable enzymes
2016
Protein engineers turned evolutionists—the quest for the optimal starting point
2019
Engineering an efficient and enantioselective enzyme for the Morita–Baylis–Hillman reaction
2021 StandoutNobel
Emergence of a catalytic tetrad during evolution of a highly active artificial aldolase
2016 StandoutNobel
Hydrogen exchange mass spectrometry for studying protein structure and dynamics
2010
Counteracting tabun inhibition by reactivation by pyridinium aldoximes that interact with active center gorge mutants of acetylcholinesterase
2019 StandoutNobel
Improved protein structure prediction using potentials from deep learning
2020 StandoutNatureNobel
Membrane protein structural bioinformatics
2011
Enzyme Engineering by Targeted Libraries
2013
Enantioselective Enzymes by Computational Design and In Silico Screening
2015 StandoutNobel
De novo design of a fluorescence-activating β-barrel
2018 StandoutNatureNobel
Alternate States of Proteins Revealed by Detailed Energy Landscape Mapping
2010 StandoutNobel
Biomolecular modeling and simulation: a field coming of age
2011
Picoliter Cell Lysate Assays in Microfluidic Droplet Compartments for Directed Enzyme Evolution
2012
CASP9 assessment of free modeling target predictions
2011
I-TASSER: a unified platform for automated protein structure and function prediction
2010 Standout
Post-exposure treatment of VX poisoned guinea pigs with the engineered phosphotriesterase mutant C23: A proof-of-concept study
2014
Connectivity between Catalytic Landscapes of the Metallo-β-Lactamase Superfamily
2014
The robustness and innovability of protein folds
2014
Catalytic efficiencies of directly evolved phosphotriesterase variants with structurally different organophosphorus compounds in vitro
2015 StandoutNobel
Luminescent probes and sensors for temperature
2013 Standout
A Membrane Burial Potential with H-Bonds and Applications to Curved Membranes and Fast Simulations
2018 StandoutNobel
One in a Million: Flow Cytometric Sorting of Single Cell-Lysate Assays in Monodisperse Picolitre Double Emulsion Droplets for Directed Evolution
2014
Assessment of template‐free modeling in CASP10 and ROLL
2013
Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications
2019 Standout
Overcoming an optimization plateau in the directed evolution of highly efficient nerve agent bioscavengers
2017 StandoutNobel
Multidimensional SuFEx Click Chemistry: Sequential Sulfur(VI) Fluoride Exchange Connections of Diverse Modules Launched From An SOF4 Hub
2017 StandoutNobel
An automatic method for CASP9 free modeling structure prediction assessment
2011
Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently
2014
Engineering enzymes for noncanonical amino acid synthesis
2018 StandoutNobel
Syrian gas attack reinforces need for better anti-sarin drugs
2013
SWISS-MODEL: homology modelling of protein structures and complexes
2018 Standout
The Moderately Efficient Enzyme: Futile Encounters and Enzyme Floppiness
2015
MULTICOM: a multi-level combination approach to protein structure prediction and its assessments in CASP8
2010
Design of Protein Catalysts
2013
Water electrolysis: from textbook knowledge to the latest scientific strategies and industrial developments
2022 Standout
Enzymes for the Homeland Defense: Optimizing Phosphotriesterase for the Hydrolysis of Organophosphate Nerve Agents
2012
Enzymatic construction of highly strained carbocycles
2018 StandoutScienceNobel
Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes (II)
2018 Standout
Directed Evolution of Protein Catalysts
2018
Imidazole Aldoximes Effective in Assisting Butyrylcholinesterase Catalysis of Organophosphate Detoxification
2014 StandoutNobel
Catalytic detoxification
2011 Nature
Hot nanoparticles light up cancer
2010
How significant is a protein structure similarity with TM-score = 0.5?
2010
Molecular Engineering of Organophosphate Hydrolysis Activity from a Weak Promiscuous Lactonase Template
2013
Perspective: Defining and quantifying the role of dynamics in enzyme catalysis
2016 Nobel
Chemomimetic Biocatalysis: Exploiting the Synthetic Potential of Cofactor-Dependent Enzymes To Create New Catalysts
2015 StandoutNobel
Predicting Three-Dimensional Structures of Transmembrane Domains of β-Barrel Membrane Proteins
2011
Variants of Phosphotriesterase for the Enhanced Detoxification of the Chemical Warfare Agent VR
2015
Improving the Catalytic Performance of an Artificial Metalloenzyme by Computational Design
2015 StandoutNobel
In vitro and in vivo efficacy of PEGylated diisopropyl fluorophosphatase (DFPase)
2011
Catalytic Soman Scavenging by the Y337A/F338A Acetylcholinesterase Mutant Assisted with Novel Site-Directed Aldoximes
2015
Enzymatic Neutralization of the Chemical Warfare Agent VX: Evolution of Phosphotriesterase for Phosphorothiolate Hydrolysis
2013
Engineering V-Type Nerve Agents Detoxifying Enzymes Using Computationally Focused Libraries
2013 StandoutNobel
Impact of scaffold rigidity on the design and evolution of an artificial Diels-Alderase
2014 StandoutNobel
PTRAJ and CPPTRAJ: Software for Processing and Analysis of Molecular Dynamics Trajectory Data
2013 Standout
A Population-Based Experimental Model for Protein Evolution: Effects of Mutation Rate and Selection Stringency on Evolutionary Outcomes
2013
Computerbasiertes Enzymdesign
2013 StandoutNobel
Works of Moshe Ben‐David being referenced
Catalytic Stimulation by Restrained Active-Site Floppiness—The Case of High Density Lipoprotein-Bound Serum Paraoxonase-1
2015
Catalytic Versatility and Backups in Enzyme Active Sites: The Case of Serum Paraoxonase 1
2012
Assessment of CASP8 structure predictions for template free targets
2009
A new thermography-based approach to early detection of cancer utilizing magnetic nanoparticles theory simulation and in vitro validation
2010
Catalytic Metal Ion Rearrangements Underline Promiscuity and Evolvability of a Metalloenzyme
2013
Directed evolution of hydrolases for prevention of G-type nerve agent intoxication
2011
Evolved Stereoselective Hydrolases for Broad-Spectrum G-Type Nerve Agent Detoxification
2012
Active Site Hydrophobicity and the Convergent Evolution of Paraoxonase Activity in Structurally Divergent Enzymes: The Case of Serum Paraoxonase 1
2016