Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo
2010 StandoutNobel
Atomic-Level Characterization of the Structural Dynamics of Proteins
2010 StandoutScienceNobel
Dishevelled 2 Recruits ß-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4
2003 StandoutScienceNobel
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gßγ
2003 StandoutScienceNobel
α-Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro
2010 StandoutScienceNobel
EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy
2004 StandoutScience
Src kinase activation by direct interaction with the integrin β cytoplasmic domain
2003
A Smad action turnover switch operated by WW domain readers of a phosphoserine code
2011
Mechanism of Activation and Inhibition of the HER4/ErbB4 Kinase
2008
Hallmarks of Cancer: The Next Generation
2011 Standout
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
Structure of a mammalian ryanodine receptor
2014 StandoutNatureNobel
Discoveries in structure and physiology of mechanically activated ion channels
2020 StandoutNatureNobel
TGF-β inhibits p70 S6 kinase via protein phosphatase 2A to induce G1 arrest
2000
Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus
2003 Standout
The Structural Basis for Autoinhibition of FLT3 by the Juxtamembrane Domain
2004
Smad transcription factors
2005 Standout
Mechanosensation of cyclical force by PIEZO1 is essential for innate immunity
2019 Nature
Structural and Energetic Mechanisms of Cooperative Autoinhibition and Activation of Vav1
2010
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Structural Basis for Autoinhibition of the EphB2 Receptor Tyrosine Kinase by the Unphosphorylated Juxtamembrane Region
2001
TGFβ signalling in context
2012 Standout
Nucleocytoplasmic shuttling of Smad proteins
2008
Structural insights on Smad function in TGFβ signaling
2001
Piezo proteins are pore-forming subunits of mechanically activated channels
2012 StandoutNatureNobel
Smad2 Nucleocytoplasmic Shuttling by Nucleoporins CAN/Nup214 and Nup153 Feeds TGFβ Signaling Complexes in the Cytoplasm and Nucleus
2002
DC-SIGN
2000 StandoutNobel
Smad-dependent and Smad-independent pathways in TGF-β family signalling
2003 StandoutNature
Recent advances in the application of expressed protein ligation to protein engineering
2002
An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor
2006
E2F4/5 and p107 as Smad Cofactors Linking the TGFβ Receptor to c-myc Repression
2002
Making the T Cell Receptor Go the Distance: A Topological View of T Cell Activation
1997
Regulation of tyrosine kinase activation and granule release through β-arrestin by CXCR1
2000
Visualizing the mechanical activation of Src
2005 StandoutNatureNobel
Crystal Structure of the MuSK Tyrosine Kinase
2002
FKBP12 Is a Negative Regulator of Transforming Growth Factor-β Receptor Internalization
2000
Structural Basis for the Autoinhibition and STI-571 Inhibition of c-Kit Tyrosine Kinase
2004
Signaling clusters in the cell membrane
2011
Structural Basis of Smad1 Activation by Receptor Kinase Phosphorylation
2001
Rewiring cell signaling: the logic and plasticity of eukaryotic protein circuitry
2004
Structure and autoregulation of the insulin-like growth factor 1 receptor kinase.
2001
Eph signaling: a structural view
2002
A Eukaryotic-like Serine/Threonine Kinase Protects Staphylococci against Phages
2016
A role of PIEZO1 in iron metabolism in mice and humans
2021 StandoutNobel
Attenuated T Cell Responses to a High-Potency Ligand In Vivo
2010 StandoutNobel
Autoregulatory Mechanisms in Protein-tyrosine Kinases
1998
A receptor kinase gene of the LysM type is involved in legumeperception of rhizobial signals
2003 Nature
The BMP7/ActRII Extracellular Domain Complex Provides New Insights into the Cooperative Nature of Receptor Assembly
2003
Reading protein modifications with interaction domains
2006
A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior
2008 StandoutNobel
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
β-Arrestin1 Interacts with the Catalytic Domain of the Tyrosine Kinase c-SRC
2000 StandoutNobel
T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation
2008
Structural Mechanism of Smad4 Recognition by the Nuclear Oncoprotein Ski
2002
A tyrosine kinase and its activator control the activity of the CtsR heat shock repressor in B. subtilis
2005
Chk2 Oligomerization Studied by Phosphopeptide Ligation
2008 StandoutNobel
De novo design of bioactive protein switches
2019 StandoutNatureNobel
An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior
2005 StandoutNobel
EMT: 2016
2016 Standout
Switching on kinases: oncogenic activation of BRAF and the PDGFR family
2004
Neuroligins and neurexins link synaptic function to cognitive disease
2008 StandoutNatureNobel
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
Plant recognition of symbiotic bacteria requires two LysM receptor-like kinases
2003 StandoutNature
FKBP12.6 Deficiency and Defective Calcium Release Channel (Ryanodine Receptor) Function Linked to Exercise-Induced Sudden Cardiac Death
2003
CASK Functions as a Mg2+-Independent Neurexin Kinase
2008 StandoutNobel
Balancing BMP Signaling through Integrated Inputs into the Smad1 Linker
2007
An Open-and-Shut Case? Recent Insights into the Activation of EGF/ErbB Receptors
2003
Functional reconstitution and characterization of AqpZ, the E. coli water channel protein
1999 StandoutNobel
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
2003 StandoutNature
Nucleocytoplasmic Shuttling of Smads 2, 3, and 4 Permits Sensing of TGF-β Receptor Activity
2002
Seven-transmembrane-spanning receptors and heart function
2002 StandoutNatureNobel
The Juxtamembrane Region of the EGF Receptor Functions as an Activation Domain
2009
How cells read TGF-β signals
2000 Standout
Juxtamembrane autoinhibition in receptor tyrosine kinases
2004
PPM1A Functions as a Smad Phosphatase to Terminate TGFβ Signaling
2006
The Biology of CRISPR-Cas: Backward and Forward
2018 StandoutNobel
Transient Non-native Hydrogen Bonds Promote Activation of a Signaling Protein
2009
TGFβ Signaling in Growth Control, Cancer, and Heritable Disorders
2000 Standout
Structural Basis for the Autoinhibition of c-Abl Tyrosine Kinase
2003 Standout
Structure of Smad1 MH1/DNA complex reveals distinctive rearrangements of BMP and TGF-β effectors
2010
Microenvironmental regulation of tumor progression and metastasis
2013 Standout
Development and Maintenance of Regulatory T cells
2013 StandoutNobel
NEW EMBO MEMBERS REVIEW: Transcriptional control by the TGF-beta/Smad signaling system
2000 Standout
Hematopoiesis Controlled by Distinct TIF1γ and Smad4 Branches of the TGFβ Pathway
2006
Regulation of the p300 HAT domain via a novel activation loop
2004
Regulation of Protein Kinases
2004
FKBP12 Binding Modulates Ryanodine Receptor Channel Gating
2001
TCR–peptide–MHC interactions in situ show accelerated kinetics and increased affinity
2010 Nature
Protein semi-synthesis: New proteins for functional and structural studies
2005
Silencing of TGF-β signalling by the pseudoreceptor BAMBI
1999 Nature
Stoichiometry of Active Smad-Transcription Factor Complexes on DNA
2002
Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response
2018 Standout
Controlling TGF-β signaling
2000
IL-2–dependent adaptive control of NK cell homeostasis
2013
A ligand-reversible dimerization system for controlling protein–protein interactions
2000
Cyanogen Bromide Cleavage Generates Fragments Suitable for Expressed Protein and Glycoprotein Ligation
2004 StandoutNobel
McsB Is a Protein Arginine Kinase That Phosphorylates and Inhibits the Heat-Shock Regulator CtsR
2009 StandoutScienceNobel
Chemical Glycobiology
2001 StandoutScienceNobel
β-Arrestin-Dependent Formation of β 2 Adrenergic Receptor-Src Protein Kinase Complexes
1999 StandoutScienceNobel
Solid-Phase Synthesis of Thioether-Linked Glycopeptide Mimics for Application to Glycoprotein Semisynthesis
2002 StandoutNobel
Semisynthesis of Proteins by Expressed Protein Ligation
2003
Bone Morphogenetic Protein Receptor Complexes on the Surface of Live Cells: A New Oligomerization Mode for Serine/Threonine Kinase Receptors
2000
β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3
2000 StandoutScienceNobel
The Biology of Interleukin-2
2007
CELLULAR FUNCTIONS REGULATED BY SRC FAMILY KINASES
1997 Standout
Expressed protein ligation: A general method for protein engineering
1998
SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor β signaling
1999
SPECIFICITY AND VERSATILITY IN TGF-β SIGNALING THROUGH SMADS
2005 Standout
Structural Basis of Smad2 Recognition by the Smad Anchor for Receptor Activation
2000 Science
Comparative Analysis of Mutant Tyrosine Kinase Chemical Rescue
2009 StandoutNobel
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Controlling TGF-beta signaling.
2000 Standout
Comparative analysis of TCR and CAR signaling informs CAR designs with superior antigen sensitivity and in vivo function
2021
De novo design of protein logic gates
2020 StandoutScienceNobel
Transduction of Receptor Signals by ß-Arrestins
2005 StandoutScienceNobel
EGF receptor gene mutations are common in lung cancers from “never smokers” and are associated with sensitivity of tumors to gefitinib and erlotinib
2004 Standout
Works of Morgan Huse being referenced
Crystal Structure of the Cytoplasmic Domain of the Type I TGF β Receptor in Complex with FKBP12
1999
Mechanical forces in the immune system
2017
Novel Foxo1-dependent transcriptional programs control Treg cell function
2012 Nature
Activation of the Sire-family tyrosine kinase Hck by SH3 domain displacement
1997 Nature
The Conformational Plasticity of Protein Kinases
2002
A Zn2+ Ion Links the Cytoplasmic Tail of CD4 and the N-terminal Region of Lck
1998
The TGFβ Receptor Activation Process
2001
Crystal Structure of a Phosphorylated Smad2
2001
Cytotoxic T Cells Use Mechanical Force to Potentiate Target Cell Killing
2016
T cells use two directionally distinct pathways for cytokine secretion
2006
CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape
2019 Nature
Agonist/endogenous peptide–MHC heterodimers drive T cell activation and sensitivity
2005 Nature
Efficient Semisynthesis of a Tetraphosphorylated Analogue of the Type I TGFβ Receptor
2001
Semisynthesis of Phosphovariants of Smad2 Reveals a Substrate Preference of the Activated TβRI Kinase
2004
T Cells as a Self-Referential, Sensory Organ
2007
IL-2–dependent tuning of NK cell sensitivity for target cells is controlled by regulatory T cells
2013
Semisynthesis of Hyperphosphorylated Type I TGFβ Receptor: Addressing the Mechanism of Kinase Activation
2000
The T-cell-receptor signaling network
2009