Citation Impact
Citing Papers
Uracil DNA Glycosylase Activity Is Dispensable for Immunoglobulin Class Switch
2004 StandoutScienceNobel
AID Enzyme-Induced Hypermutation in an Actively Transcribed Gene in Fibroblasts
2002 StandoutScienceNobel
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney
2006 StandoutNobel
Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons
2013 StandoutNobel
Induction of human neuronal cells by defined transcription factors
2011 StandoutNatureNobel
Regulation of Cardiac Gene Expression by GATA-4/5/6
1997
Negative Transcriptional Regulation of the Interferon-γ Promoter by Glucocorticoids and Dominant Negative Mutants of c-Jun
1995
Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice
2008
Comparison of Femtosecond Laser and Continuous Wave UV Sources for Protein–Nucleic Acid Crosslinking
2007
Rapid transcriptional activation and early mRNA turnover of brain natriuretic peptide in cardiocyte hypertrophy. Evidence for brain natriuretic peptide as an "emergency" cardiac hormone against ventricular overload.
1995
Discoveries in structure and physiology of mechanically activated ion channels
2020 StandoutNatureNobel
Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration
1995 StandoutNobel
15-Deoxy-Δ12,14-Prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ
1995 Standout
Inhibition of nuclear hormone receptor activity by calreticulin
1994 Nature
The Glucocorticoid Receptor Is Tethered to DNA-bound Oct-1 at the Mouse Gonadotropin-releasing Hormone Distal Negative Glucocorticoid Response Element
1999
Atrial natriuretic factor gene expression in ventricles of rats with spontaneous biventricular hypertrophy.
1988
Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor
1990
TRIBE: Hijacking an RNA-Editing Enzyme to Identify Cell-Specific Targets of RNA-Binding Proteins
2016 StandoutNobel
Genes Expressed in Neurons of Adult Male Drosophila
1997 StandoutNobel
DNA Binding of the Glucocorticoid Receptor Is Not Essential for Survival
1998
The AID enzyme induces class switch recombination in fibroblasts
2002 StandoutNatureNobel
Direct Activation of a GATA6 Cardiac Enhancer by Nkx2.5: Evidence for a Reinforcing Regulatory Network of Nkx2.5 and GATA Transcription Factors in the Developing Heart
2000
The rat ortholog of the presumptive flounder antifreeze enhancer‐binding protein is a helicase domain‐containing protein
2000
Insertion/deletion polymorphism within a polyadenylate stretch at the human atrial natriuretic peptides (hANP) gene locus
1994
Molecular Determinants of Glucocorticoid Receptor Function and Tissue Sensitivity to Glucocorticoids
1996
Haemodynamics determined by a genetic programme govern asymmetric development of the aortic arch
2007 Nature
Making or Breaking the Heart: From Lineage Determination to Morphogenesis
2006
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction
1990 Standout
IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages
2003
Glucocorticoids and Stress: Permissive and Suppressive Actions
1994
The Drosophila gene tailless is expressed at the embryonic termini and is a member of the steroid receptor superfamily
1990 StandoutNobel
Cardiac-specific overexpression of AT1 receptor mutant lacking G q/G i coupling causes hypertrophy and bradycardia in transgenic mice
2005
Multipotent Flk-1+ Cardiovascular Progenitor Cells Give Rise to the Cardiomyocyte, Endothelial, and Vascular Smooth Muscle Lineages
2006
Differentiation of embryonic stem cells is induced by GATA factors
2002
A fusion protein required for vesicle-mediated transport in both mammalian cells and yeast
1989 StandoutNatureNobel
Synthetic Glucocorticoids That Dissociate Transactivation and AP-1 Transrepression Exhibit Antiinflammatory Activityin Vivo
1997
Identification of the Mouse Neuromuscular Degeneration Gene and Mapping of a Second Site Suppressor Allele
1998
Modulation of guanylate cyclase-coupled atrial natriuretic factor receptor activity by mastoparan and ANF in murine Leydig tumor cells: Role of G-proteins
1994
Multiple Roles and Interactions of Tbx4 and Tbx5 in Development of the Respiratory System
2012
The Drosophila gene torso encodes a putative receptor tyrosine kinase
1989 StandoutNatureNobel
Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors
2010 Standout
Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse
1995 StandoutNobel
GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5
2003 StandoutNature
The genomic clone G-21 which resembles a β-adrenergic receptor sequence encodes the 5-HT1A receptor
1988 StandoutNatureNobel
Seven-transmembrane-spanning receptors and heart function
2002 StandoutNatureNobel
Human Intestinal H+/Peptide Cotransporter
1995
Instruction of Distinct CD4 T Helper Cell Fates by Different Notch Ligands on Antigen-Presenting Cells
2004 StandoutNobel
Integrase-mediated spacer acquisition during CRISPR–Cas adaptive immunity
2015 StandoutNatureNobel
Characterization of the 5?-flanking region and chromosomal assignment of the human brain natriuretic peptide gene
1995
M-CAT, CArG, and Sp1 Elements Are Required for α1-Adrenergic Induction of the Skeletal α-Actin Promoter during Cardiac Myocyte Hypertrophy
1995
The Transcription Factor GATA-3 Is Necessary and Sufficient for Th2 Cytokine Gene Expression in CD4 T Cells
1997 Standout
A Calcineurin-Dependent Transcriptional Pathway for Cardiac Hypertrophy
1998 Standout
Local Supercoil-Stabilized DNA Structure
1991
Investigation of the polymorphic ScaI site by a PCR-based assay at the human atrial natriuretic peptides (hANP) gene locus
1992
The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES Cells
2003 StandoutNobel
Calcium signaling
1995 Standout
Murine pulmonary myocardium: Developmental analysis of cardiac gene expression
1994
Gene regulation by steroid hormones
1989 Standout
Sμbp-2 Represses the Epstein–Barr Virus Lytic Switch Promoter
1999
A new polymorphic restriction site at the human atrial natriuretic peptide (hANP) gene locus
1993
Fluid Dynamics of Heart Development
2011
Glucocorticoids Repress Transcription from a Negative Glucocorticoid Response Element Recognized by Two Homeodomain-containing Proteins, Pbx and Oct-1
1998
G-proteins in growth and apoptosis: lessons from the heart
2001
Molecular Characterization of a Functional cDNA Encoding the Serotonin 1c Receptor
1988 StandoutScienceNobel
Atrial Natriuretic Factor-SV40 T Antigen Transgenes Produce Tumors and Cardiac Arrhythmias in Mice
1988 Science
GATA4 transcription factor is required for ventral morphogenesis and heart tube formation.
1997
Selective regulation of the atrial natriuretic peptide gene by individual components of the activator protein-1 complex.
1996
Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5.
1995
Negative cross-talk between RelA and the glucocorticoid receptor: a possible mechanism for the antiinflammatory action of glucocorticoids.
1995
Tbx20 acts upstream of Wnt signaling to regulate endocardial cushion formation and valve remodeling during mouse cardiogenesis
2013
Novel mechanism of glucocorticoid-mediated gene repression. Nuclear factor-kappa B is target for glucocorticoid-mediated interleukin 8 gene repression.
1994
Signaling in Myocardial Hypertrophy
1999
Purified glucocorticoid receptors bind selectively in vitro to a cloned DNA fragment that mediates a delayed secondary response to glucocorticoids in vivo.
1990
Transcription Factor Interactions: Selectors of Positive or Negative Regulation from a Single DNA Element
1990 Science
Hypertension Associated with Decreased Testosterone Levels in Natriuretic Peptide Receptor-A Gene-Knockout and Gene-Duplicated Mutant Mouse Models1
1999 StandoutNobel
Effect of atrial natriuretic peptide on gonadotropin release in superfused rat pituitary cells.
1986 Nobel
Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity.
1986 Standout
GATA factors efficiently direct cardiac fate from embryonic stem cells
2013
A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP-1.
1994
Glucocorticoid inhibition of transcription from episomal proopiomelanocortin gene promoter.
1986
Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation.
1995
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.
1995 StandoutNobel
Dexamethasone inhibits mitogen induction of the TIS10 prostaglandin synthase/cyclooxygenase gene.
1992
Chimeric α 2 -,β 2 -Adrenergic Receptors: Delineation of Domains Involved in Effector Coupling and Ligand Binding Specificity
1988 StandoutScienceNobel
Enhanced Myocardial Function in Transgenic Mice Overexpressing the β 2 -Adrenergic Receptor
1994 StandoutScienceNobel
The alpha 1A-adrenergic receptor subtype mediates biochemical, molecular, and morphologic features of cultured myocardial cell hypertrophy
1993
Molecular Mechanism of Class Switch Recombination: Linkage with Somatic Hypermutation
2002 StandoutNobel
Myocyte Adrenoceptor Signaling Pathways
2003 StandoutScienceNobel
An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins
1987 StandoutNatureNobel
Bcl-2-mediated alterations in endoplasmic reticulum Ca 2+ analyzed with an improved genetically encoded fluorescent sensor
2004 StandoutNobel
The Cardiac Transcription Network Modulated by Gata4, Mef2a, Nkx2.5, Srf, Histone Modifications, and MicroRNAs
2011
Glucocorticoid-induced apoptosis of human leukemic cells is caused by the repressive function of the glucocorticoid receptor.
1995
Targeting the Receptor-G q Interface to Inhibit in Vivo Pressure Overload Myocardial Hypertrophy
1998 StandoutScienceNobel
Pivotal Role of a gp91 phox -Containing NADPH Oxidase in Angiotensin II-Induced Cardiac Hypertrophy in Mice
2002
Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors
1986 Nature
Piezo1, a mechanically activated ion channel, is required for vascular development in mice
2014 StandoutNobel
Mechanically activated piezo channels modulate outflow tract valve development through the Yap1 and Klf2-Notch signaling axis
2019
GATA4 is essential for formation of the proepicardium and regulates cardiogenesis
2004
How Do Glucocorticoids Influence Stress Responses? Integrating Permissive, Suppressive, Stimulatory, and Preparative Actions*
2000 Standout
Molecular analysis of the inhibition of interleukin-8 production by dexamethasone in a human fibrosarcoma cell line.
1992
cis -Acting Sequences That Mediate Induction of β-Myosin Heavy Chain Gene Expression During Left Ventricular Hypertrophy due to Aortic Constriction
1997
Mutual transrepression of Fos and the glucocorticoid receptor: involvement of a functional domain in Fos which is absent in FosB.
1990
Brain Corticosteroid Receptor Balance in Health and Disease*
1998 Standout
cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor.
1987 StandoutNobel
Quantitative analysis of the glucocorticoid receptor-DNA interaction at the mouse mammary tumor virus glucocorticoid response element.
1990
Atrial Natriuretic Factor
1989
Gq- and ras-dependent pathways mediate hypertrophy of neonatal rat ventricular myocytes following alpha 1-adrenergic stimulation.
1994
daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans
1997 StandoutScienceNobel
Cloning, Sequencing, and Expression of the Gene Coding for the Human Platelet α 2 -Adrenergic Receptor
1987 StandoutScienceNobel
Protein-DNA interactions at a dioxin-responsive enhancer. Analysis of six bona fide DNA-binding sites for the liganded Ah receptor.
1993
Alteration of Stimulus-Specific Guard Cell Calcium Oscillations and Stomatal Closing in Arabidopsis det3 Mutant
2000 StandoutScienceNobel
Differential Expression and Autoradiographic Localization of Atrial Natriuretic Peptide Receptor in Spontaneously Hypertensive and Normotensive Rat Testes: Diminution of Testosterone in Hypertension
1996
Glucocorticoid-mediated repression of nuclear factor-κBdependent transcription involves direct interference with transactivation
1997
Activation of the grp78 and grp94 Promoters by Hepatitis C Virus E2 Envelope Protein
1999 StandoutNobel
Genetic Decreases in Atrial Natriuretic Peptide and Salt-Sensitive Hypertension
1995 StandoutScienceNobel
Angiotensin II type 1a receptor gene expression in the heart: AP-1 and GATA-4 participate in the response to pressure overload
1997
Molecular cloning and expression of the cDNA for the hamster alpha 1-adrenergic receptor.
1988 StandoutNobel
Bcl-2 decreases the free Ca 2+ concentration within the endoplasmic reticulum
2000
Physical Interaction between TBX5 and MEF2C Is Required for Early Heart Development
2009
Elevated blood pressures in mice lacking endothelial nitric oxide synthase
1996 StandoutNobel
Works of Mona Nemer being referenced
A Murine Model of Holt-Oram Syndrome Defines Roles of the T-Box Transcription Factor Tbx5 in Cardiogenesis and Disease
2001
Pro‐opiomelanocortin gene: A model for negative regulation of transcription by glucocorticoids
1987
Loss of Gata5 in mice leads to bicuspid aortic valve
2011
GATA5 interacts with GATA4 and GATA6 in outflow tract development
2011
Modulation of gene expression by calreticulin binding to the glucocorticoid receptor
1994 Nature
Transcriptional activation of BMP-4 and regulation of mammalian organogenesis by GATA-4 and -6
2003
Localization of the Catf1 transcription factor gene to mouse Chromosome 19
1995
Glucocorticoid repression of pro-opiomelanocortin gene transcription
1989
Gene structure of human cardiac hormone precursor, pronatriodilatin
1984 Nature
The Atrial Natriuretic Factor Promoter Is a Downstream Target for Nkx-2.5 in the Myocardium
1996
Homodimer formation is rate-limiting for high affinity DNA binding by glucocorticoid receptor.
1992
A hormone-encoding gene identifies a pathway for cardiac but not skeletal muscle gene transcription.
1994
Inhibition of Transcription Factor GATA-4 Expression Blocks In Vitro Cardiac Muscle Differentiation
1995
A nuclear pathway for alpha 1-adrenergic receptor signaling in cardiac cells.
1993
GATA-4 and Nkx-2.5 Coactivate Nkx-2 DNA Binding Targets: Role for Regulating Early Cardiac Gene Expression
1998
The mouse Gata4 transcription factor maps to Chromosome 14
1995
Molecular cloning and characterization of DNA sequences encoding rat and human atrial natriuretic factors.
1984
Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development
2005
The pronatriodilatin gene is located on the distal short arm of human chromosome 1 and on mouse chromosome 4.
1985
Xhol polymorphism at the human pronatriodilatin (hPND) gene locus
1986
Glucocorticoid Receptor Binding to a Specific DNA Sequence Is Required for Hormone-Dependent Repression of Pro-Opiomelanocortin Gene Transcription
1989
An endocardial pathway involving Tbx5, Gata4, and Nos3 required for atrial septum formation
2010
fos/jun repression of cardiac-specific transcription in quiescent and growth-stimulated myocytes is targeted at a tissue-specific cis element.
1993
Structure of the rat pro‐opiomelanocortin (POMC) gene
1985
Taql polymorphism at the 3′ end of the human pronatriodilatin gene (hPND)
1986
Expression of atrial natriuretic factor gene in heart ventricular tissue
1986
fos/jun Repression of Cardiac-Specific Transcription in Quiescent and Growth-Stimulated Myocytes is Targeted at a Tissue-Specific cis element
1993
Overexpression of angiotensin II type I receptor in cardiomyocytes induces cardiac hypertrophy and remodeling
2000
The atrial natriuretic peptide system in rat ovaries.
1993
The gene for rat atrial natriuretic factor.
1985
A Hormone-Encoding Gene Identifies a Pathway for Cardiac but Not Skeletal Muscle Gene Transcription
1994
Control of segmental expression of the cardiac-restricted ankyrin repeat protein gene by distinct regulatory pathways in murine cardiogenesis
1999
Novel glucocorticoid receptor complex with DNA element of the hormone-repressed POMC gene.
1993
Enhanced cardiogenesis in embryonic stem cells overexpressing the GATA-4 transcription factor
1997
The atrial natriuretic factor: Its physiology and biochemistry
1988
Glucocorticoid receptor binding to a specific DNA sequence is required for hormone-dependent repression of pro-opiomelanocortin gene transcription.
1989