Citation Impact
Citing Papers
Chromosomal Instability Confers Intrinsic Multidrug Resistance
2011
Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gßγ
2003 StandoutScienceNobel
Genome-wide identification and functional analysis of Apobec-1-mediated C-to-U RNA editing in mouse small intestine and liver
2014
Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota
2012 StandoutScience
Loss of cryptochrome reduces cancer risk in p53 mutant mice
2009 StandoutNobel
Autoregulation of E-cadherin expression by cadherin–cadherin interactions
2003
Morphology of sporadic colorectal cancer with DNA replication errors
1998
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
2014 StandoutNobel
Mutational landscape and significance across 12 major cancer types
2013 StandoutNature
Mismatch Repair Processing of Carcinogen-DNA Adducts Triggers Apoptosis
1999
Hallmarks of Cancer: The Next Generation
2011 Standout
Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m 6 A-demethylation of NANOG mRNA
2016 StandoutNobel
The DNA-damage response in human biology and disease
2009 StandoutNature
Stem cells: the intestinal stem cell as a paradigm
2000
Base-excision repair of oxidative DNA damage
2007 StandoutNature
Caught up in a Wnt storm: Wnt signaling in cancer
2003
β-Catenin regulates expression of cyclin D1 in colon carcinoma cells
1999 StandoutNature
Structural basis of the Axin–adenomatous polyposis coli interaction
2000
Stem cells, cancer, and cancer stem cells
2001 StandoutNature
Microsatellite Instability and High Content of Activated Cytotoxic Lymphocytes Identify Colon Cancer Patients with a Favorable Prognosis
2001
DNA methylation in endometrial cancer
2010
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
PPARδ Is an APC-Regulated Target of Nonsteroidal Anti-Inflammatory Drugs
1999
Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of β-catenin, and enhanced tumor cell invasion
2003
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
2006 StandoutNobel
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
The mini-driver model of polygenic cancer evolution
2015 StandoutNobel
Wnt proteins are lipid-modified and can act as stem cell growth factors
2003 StandoutNature
The Hedgehog and Wnt signalling pathways in cancer
2001 StandoutNature
Inflammation and colorectal cancer: IBD-associated and sporadic cancer compared
2002
Oncogenic K-ras Stimulates Wnt Signaling in Colon Cancer Through Inhibition of GSK-3β
2005
Synergistic Activation of the Wnt Signaling Pathway by Dvl and Casein Kinase Iε
2001
The circadian clock: pacemaker and tumour suppressor
2003
Wnt signaling in the intestinal epithelium: from endoderm to cancer
2005
Telomere Dysfunction Increases Mutation Rate and Genomic Instability
2001 StandoutNobel
A microenvironmental model of carcinogenesis
2007
Smoking and Colorectal Cancer
2008
Fibroblast-Derived Exosomes Contribute to Chemoresistance through Priming Cancer Stem Cells in Colorectal Cancer
2015
Integrated genomic characterization of endometrial carcinoma
2013 StandoutNature
Germline Susceptibility to Colorectal Cancer Due to Base-Excision Repair Gene Defects
2005
The ABC of APC
2001
Apc modulates embryonic stem-cell differentiation by controlling the dosage of β-catenin signaling
2002
A role for Wnt signalling in self-renewal of haematopoietic stem cells
2003 StandoutNature
Immunity, Inflammation, and Cancer
2010 Standout
Prevalence of the Y165C, G382D and 1395delGGA germline mutations of the MYH gene in Italian patients with adenomatous polyposis coli and colorectal adenomas
2004
Deficiency of SPARC suppresses intestinal tumorigenesis in APC Min/+ mice
2007 StandoutNobel
Linking Colorectal Cancer to Wnt Signaling
2000
DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice
2008
Hereditary Colorectal Cancer
2003 Standout
Insight into the Functional Consequences of Inherited Variants of the hMYH Adenine Glycosylase Associated with Colorectal Cancer: Complementation Assays with hMYH Variants and Pre-steady-state Kinetics of the Corresponding Mutated E.coli Enzymes
2003
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Argonaute CLIP Defines a Deregulated miR-122-Bound Transcriptome that Correlates with Patient Survival in Human Liver Cancer
2017 StandoutNobel
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
2018 StandoutNobel
Clonal evolution in cancer
2012 StandoutNature
An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of β-catenin
1999
The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores
2009 Standout
Modulation of Wnt signaling by Axin and Axil
1999
Cyclin D1 Is Not an Immediate Target of β-Catenin following Apc Loss in the Intestine
2005
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Wnt signalling in stem cells and cancer
2005 StandoutNature
Crypt stem cells as the cells-of-origin of intestinal cancer
2008 StandoutNature
Identification of stem cells in small intestine and colon by marker gene Lgr5
2007 StandoutNature
Roles of PPARs in health and disease
2000 StandoutNature
Clonality Assessment and Clonal Ordering of Individual Neoplastic Crypts Shows Polyclonality of Colorectal Adenomas
2010
Heterogeneous expression of Wnt/β‐catenin target genes within colorectal cancer
2007
The cancer genome
2009 StandoutNature
Cancer genetics: colorectal cancer as a model
2006
Convergence of Wnt, ß-Catenin, and Cadherin Pathways
2004 StandoutScience
Emerging role of nanog in tumorigenesis and cancer stem cells
2013
The von Hippel–Lindau tumor suppressor gene product represses oncogenic β-catenin signaling in renal carcinoma cells
2006
A Perspective on Cancer Cell Metastasis
2011 StandoutScience
Wnt signaling and cancer
2000 Standout
Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of β-catenin
2000
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
Role of Hypoxia-Inducible Factors in Breast Cancer Metastasis
2013 StandoutNobel
The beta-catenin binding domain of adenomatous polyposis coli is sufficient for tumor suppression.
2000
Inhibition of Adipogenesis by Wnt Signaling
2000 StandoutScience
Evidence that genetic instability occurs at an early stage of colorectal tumorigenesis.
2001
Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology
2001 StandoutScience
Kinase requirements in human cells: III. Altered kinase requirements inVHL−/− cancer cells detected in a pilot synthetic lethal screen
2008 StandoutNobel
β-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins
2001 StandoutNobel
Somatic mutations of the β-catenin gene are frequent in mouse and human hepatocellular carcinomas
1998
Epigenetic Reprogramming in Cancer
2013 Science
Detection of Metabolic Alterations in Non-tumor Gastrointestinal Tissue of the ApcMin/+ Mouse by 1H MAS NMR Spectroscopy
2009
Impaired mammary gland and lymphoid development caused by inducible expression of Axin in transgenic mice
2001
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Variable β-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment
2001
Wnt/β-catenin signaling regulates the expression of the homeobox gene Cdx1 in embryonic intestine
2000
Metabolic reprogramming and cancer progression
2020 StandoutScience
Cancer Genome Landscapes
2013 StandoutScience
Systematic Review of Microsatellite Instability and Colorectal Cancer Prognosis
2005
Inhibition of the Wnt Signaling Pathway by Idax, a Novel Dvl-Binding Protein
2001
Global cancer statistics, 2012
2015 Standout
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Beta-catenin mutations in human prostate cancer.
1998
Genetic Instability Is Not a Requirement for Tumor Development
2008
Coexistence of Quiescent and Active Adult Stem Cells in Mammals
2010 StandoutScience
Loss of homotypic cell adhesion by epithelial-mesenchymal transition or mutation limits sensitivity to epidermal growth factor receptor inhibition
2007
Functional requirements of AID’s higher order structures and their interaction with RNA-binding proteins
2016 StandoutNobel
Signalling networks that cause cancer
1999
Works of Mohammad Ilyas being referenced
The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis
1999
Expression profiling of murine intestinal adenomas reveals early deregulation of multiple matrix metalloproteinase (Mmp) genes
2005
CLINICO-PATHOLOGICAL FEATURES AND p53 EXPRESSION IN LEFT-SIDED SPORADIC COLORECTAL CANCERS WITH AND WITHOUT MICROSATELLITE INSTABILITY
1996
Genetic pathways in colorectal and other cancers
1999
A CD44−/CD24+ phenotype is a poor prognostic marker in early invasive breast cancer
2011
Genetic pathways in colorectal and other cancers
1999
Defects in mismatch repair occur afterAPC mutations in the pathogenesis of sporadic colorectal tumours
1998
THE INTERACTIONS OF APC, E-CADHERIN AND β-CATENIN IN TUMOUR DEVELOPMENT AND PROGRESSION
1997
A comparison of the genetic pathways involved in the pathogenesis of three types of colorectal cancer
1998
Wnt signalling and the mechanistic basis of tumour development
2005
The Stem Cell Marker CD133 Associates with Enhanced Colony Formation and Cell Motility in Colorectal Cancer
2010
Putative direct and indirect Wnt targets identified through consistent gene expression changes in APC-mutant intestinal adenomas from humans and mice
2008
Mutated epithelial cadherin is associated with increased tumorigenicity and loss of adhesion and of responsiveness to the motogenic trefoil factor 2 in colon carcinoma cells
1999
APC mutations in sporadic colorectal tumors: A mutational “hotspot” and interdependence of the “two hits”
2000
β-Catenin mutations in cell lines established from human colorectal cancers
1997
Myh Deficiency Enhances Intestinal Tumorigenesis in Multiple Intestinal Neoplasia ( Apc Min /+) Mice
2004
Target genes of β-catenin–T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas
1999
Antibody targeting studies in a transgenic murine model of spontaneous colorectal tumors
2001
Genetic basis of variation in adenoma multiplicity in Apc Min /+ Mom1 S mice
2005
The APC variants I1307K and E1317Q are associated with colorectal tumors, but not always with a family history
1998
Embryonic NANOG Activity Defines Colorectal Cancer Stem Cells and Modulates through AP1- and TCF-dependent Mechanisms
2012
APC mutations are sufficient for the growth of early colorectal adenomas
2000
Cyclin D1 is not an essential target of beta-catenin signaling during intestinal tumorigenesis, but it may act as a modifier of disease severity in multiple intestinal neoplasia (Min) mice.
2002