Citation Impact
Citing Papers
A Small-Molecule E2F Inhibitor Blocks Growth in a Melanoma Culture Model
2008
A Novel Inhibitor of STAT3 Homodimerization Selectively Suppresses STAT3 Activity and Malignant Transformation
2013
Novel Transcriptional Potentiation of BETA2/NeuroD on the Secretin Gene Promoter by the DNA-Binding Protein Finb/RREB-1
2002
PRDX2 and PRDX4 are negative regulators of hypoxia-inducible factors under conditions of prolonged hypoxia
2016 StandoutNobel
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Head and neck squamous cell carcinoma
2020 Standout
Dendritic cells in cancer immunology and immunotherapy
2019 Standout
Mechanisms, regulation and functions of the unfolded protein response
2020 Standout
IL-6 trans-signaling promotes pancreatitis-associated lung injury and lethality
2013
An Essential Role for Senescent Cells in Optimal Wound Healing through Secretion of PDGF-AA
2014 Standout
Tumor-secreted Pros1 inhibits macrophage M1 polarization to reduce antitumor immune response
2018
Inflammation and Cancer: Triggers, Mechanisms, and Consequences
2019 Standout
Plant flavonoids: Classification, distribution, biosynthesis, and antioxidant activity
2022 Standout
Cancer nanomedicine: progress, challenges and opportunities
2016 Standout
Notch signaling targets the Wingless responsiveness of a Ubx visceral mesoderm enhancer in Drosophila
2001
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
Wnt signaling in cancer
2016 Standout
Discovery of Chromone‐Based Inhibitors of the Transcription Factor STAT5
2008
A CRISPR–dCas Toolbox for Genetic Engineering and Synthetic Biology
2018
Chronic Inflammation (Inflammaging) and Its Potential Contribution to Age-Associated Diseases
2014 Standout
NF-κB and STAT3 – key players in liver inflammation and cancer
2010
Regulation of αβ/γδ T Cell Lineage Commitment and Peripheral T Cell Responses by Notch/RBP-J Signaling
2004 StandoutNobel
New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays
2010 Standout
Regulation of Cell Adhesion and Collective Cell Migration by Hindsight and Its Human Homolog RREB1
2008
A novel small-molecule disrupts Stat3 SH2 domain–phosphotyrosine interactions and Stat3-dependent tumor processes
2010
Coordinated regulation of myeloid cells by tumours
2012 Standout
Porphyromonas gingivalis modulates Pseudomonas aeruginosa-induced apoptosis of respiratory epithelial cells through the STAT3 signaling pathway
2013
Cytosolic delivery of peptidic STAT3 SH2 domain inhibitors
2020
The STAT3 inhibitor NSC 74859 is effective in hepatocellular cancers with disrupted TGF-β signaling
2009
STAT3 inhibitors for cancer therapy
2013
Protein and ligand preparation: parameters, protocols, and influence on virtual screening enrichments
2013 Standout
Hepatocyte IKKβ/NF-κB Inhibits Tumor Promotion and Progression by Preventing Oxidative Stress-Driven STAT3 Activation
2010
Inflammation and Colon Cancer
2010 Standout
STAT transcription factors in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention
2013
Hitting the right spot: Mechanism of action of OPB‐31121, a novel and potent inhibitor of the Signal Transducer and Activator of Transcription 3 (STAT3)
2015
Fragment-based drug design and identification of HJC0123 , a novel orally bioavailable STAT3 inhibitor for cancer therapy
2013
Targeting the IL-6/JAK/STAT3 signalling axis in cancer
2018 Standout
Immunity, Inflammation, and Cancer
2010 Standout
VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400
2008 StandoutNobel
Stat3 Inhibitor Stattic Exhibits Potent Antitumor Activity and Induces Chemo- and Radio-Sensitivity in Nasopharyngeal Carcinoma
2013
Periodontitis: from microbial immune subversion to systemic inflammation
2014 Standout
CCR9 in cancer: oncogenic role and therapeutic targeting
2016
Regulation and Function of the PD-L1 Checkpoint
2018 Standout
Molecular mechanisms of T cell co-stimulation and co-inhibition
2013 Standout
Collective cell migration in morphogenesis, regeneration and cancer
2009 Standout
STATs in cancer inflammation and immunity: a leading role for STAT3
2009 Standout
Interleukin‐6 drives melanoma cell motility through p38α‐MAPK‐dependent up‐regulation of WNT5A expression
2014
Stat3 and MMP7 Contribute to Pancreatic Ductal Adenocarcinoma Initiation and Progression
2011
Chemokines in the cancer microenvironment and their relevance in cancer immunotherapy
2017 Standout
Macrophages as regulators of tumour immunity and immunotherapy
2019 Standout
Matching the power of high throughput screening to the chemical diversity of natural products
2013
Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host Metabolism
2016 Standout
Bile diversion to the distal small intestine has comparable metabolic benefits to bariatric surgery
2015
STAT signaling in the pathogenesis and treatment of myeloid malignancies
2012
LLL-3 inhibits STAT3 activity, suppresses glioblastoma cell growth and prolongs survival in a mouse glioblastoma model
2009
Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms
2013 Standout
Reactive Astrocytes: Production, Function, and Therapeutic Potential
2017 Standout
Immunotherapy of Diffuse Gliomas: Biological Background, Current Status and Future Developments
2009 Standout
Toll-like Receptor 4 Variant D299G Induces Features of Neoplastic Progression in Caco-2 Intestinal Cells and Is Associated With Advanced Human Colon Cancer
2011
Revisiting STAT3 signalling in cancer: new and unexpected biological functions
2014 Standout
Discovery of the catechol structural moiety as a Stat3 SH2 domain inhibitor by virtual screening
2008
Cancer-related inflammation and treatment effectiveness
2014 Standout
Specific GATA Factors Act as Conserved Inducers of an Endodermal-EMT
2011
Peroxiredoxin 1 Stimulates Endothelial Cell Expression of VEGF via TLR4 Dependent Activation of HIF-1α
2012
Discovery and resupply of pharmacologically active plant-derived natural products: A review
2015 Standout
Signal Transducer and Activator of Transcription‐3, Inflammation, and Cancer
2009 Standout
Metformin targets Stat3 to inhibit cell growth and induce apoptosis in triple-negative breast cancers
2012
IL-6, IL-17 and STAT3: a holy trinity in auto-immunity?
2012
NF-κB, inflammation, immunity and cancer: coming of age
2018 Standout
Hydrazinocurcumin Encapsuled Nanoparticles “Re-Educate” Tumor-Associated Macrophages and Exhibit Anti-Tumor Effects on Breast Cancer Following STAT3 Suppression
2013
Immunogenic cell death and DAMPs in cancer therapy
2012 Standout
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
The Incidence, Correlation with Tumor-Infiltrating Inflammation, and Prognosis of Phosphorylated STAT3 Expression in Human Gliomas
2008
ER stress transcription factor Xbp1 suppresses intestinal tumorigenesis and directs intestinal stem cells
2013
Phototriggerable peptidomimetics for the inhibition of Mycobacterium tuberculosis ribonucleotide reductase by targeting protein–protein binding
2014
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Identification of a New Series of STAT3 Inhibitors by Virtual Screening
2010
Small-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinoma
2016
Dpp signaling thresholds in the dorsal ectoderm of the Drosophila embryo
2000
A comprehensive review on phytochemistry, pharmacology, and flavonoid biosynthesis ofScutellaria baicalensis
2018
Signal Transducer and Activator of Transcription-3: A Molecular Hub for Signaling Pathways in Gliomas
2008
Immunology of Psoriasis
2014 Standout
Diabetes and Cancer
2010 Standout
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
A STAT3-mediated metabolic switch is involved in tumour transformation and STAT3 addiction
2010
The PDL1-PD1 Axis Converts Human T H 1 Cells into Regulatory T Cells
2011
Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts
2012
STAT3 Induces Immunosuppression by Upregulating PD-1/PD-L1 in HNSCC
2017
Marine natural products
2018 Standout
Antitumor activity of a novel small molecule STAT3 inhibitor against a human lymphoma cell line with high STAT3 activation
2011
Systems‐level interactions between insulin–EGF networks amplify mitogenic signaling
2009
Salicylic Acid Based Small Molecule Inhibitor for the Oncogenic Src Homology-2 Domain Containing Protein Tyrosine Phosphatase-2 (SHP2)
2010
Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling
2020 StandoutNobel
Inflammatory responses and inflammation-associated diseases in organs
2017 Standout
IKK/NF‐κB and STAT3 pathways: central signalling hubs in inflammation‐mediated tumour promotion and metastasis
2009
Emerging Targets in Photopharmacology
2016 StandoutNobel
Novel Method for Generating Structure-Based Pharmacophores Using Energetic Analysis
2009
Stapled β-Hairpins Featuring 4-Mercaptoproline
2021 StandoutNobel
STAT3 Is Required for Proliferation and Maintenance of Multipotency in Glioblastoma Stem Cells
2009
Competing G protein‐coupled receptor kinases balance G protein and β‐arrestin signaling
2012 StandoutNobel
Morphogen gradient interpretation
2001 StandoutNatureNobel
Works of M.L. Richard Yip being referenced
A Small-Molecule Blocking Ribonucleotide Reductase Holoenzyme Formation Inhibits Cancer Cell Growth and Overcomes Drug Resistance
2013
Identification of a Natural Compound by Cell-Based Screening That Enhances Interferon Regulatory Factor-1 Activity and Causes Tumor Suppression
2011
Baicalein upregulates DDIT4 expression which mediates mTOR inhibition and growth inhibition in cancer cells
2014
Bromotyrosine-derived metabolites from an Indonesian marine sponge in the family Aplysinellidae (Order Verongiida)
2015
Discovery of a Novel Shp2 Protein Tyrosine Phosphatase Inhibitor
2006
CCR9‐mediated signaling through β‐catenin and identification of a novel CCR9 antagonist
2015
Inhibitors of Src Homology-2 Domain Containing Protein Tyrosine Phosphatase-2 (Shp2) Based on Oxindole Scaffolds
2008
Control of germ-band retraction in Drosophila by the zinc-finger protein HINDSIGHT
1997
Identification of Oct4-activating compounds that enhance reprogramming efficiency
2012
Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity
2007