Citation Impact
Citing Papers
Discovery, mechanisms of action and combination therapy of artemisinin
2009 Standout
Strategies and tools for the control/elimination of lymphatic filariasis.
1997 Standout
Clinical practice guidelines for the sustained use of sedatives and analgesics in the critically ill adult
2002 Standout
Carbamazepine‐hypersensitivity: assessment of clinical and in vitro chemical cross‐reactivity with phenytoin and oxcarbazepine.
1991
Identification of human cytochrome P 450 s that metabolise anti-parasitic drugs and predictions of in vivo drug hepatic clearance from in vitro data
2003
Quinolines and structurally related heterocycles as antimalarials
2010 Standout
Physicochemical and Physiological Mechanisms for the Effects of Food on Drug Absorption: The Role of Lipids and pH
1997
Self-emulsifying drug delivery systems (SEDDS) for improved oral delivery of lipophilic drugs
2004 Standout
Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology
2020 Standout
Severe and complicated malaria
1990 Standout
Pulmonary drug delivery. Part I: Physiological factors affecting therapeutic effectiveness of aerosolized medications
2003 Standout
Dose calculation of anticancer drugs: a review of the current practice and introduction of an alternative.
1996 Standout
A physicochemical Basis for the Effect of Food on the Absolute Oral Bioavailability of Halofantrine
1996
Design, synthesis, and biological activities of conformationally restricted analogs of primaquine with a 1,10-phenanthroline framework
2008
Hydroxychloroquine: From Malaria to Autoimmunity
2011 Standout
Microemulsion-based media as novel drug delivery systems
2000 Standout
Risk for ovulation in women taking a low-dose oral contraceptive (Microgynon) when receiving antibacterial treatment with a fluoroquinolone (ofloxacin)
1996
Metabolism of the macrolide immunosuppressant, tacrolimus, by the pig gut mucosa in the Ussing chamber
1996
A Conscious Dog Model for Assessing the Absorption, Enterocyte‐Based Metabolism, and Intestinal Lymphatic Transport of Halofantrine
2001
Mechanism-Based Inactivation (MBI) of Cytochrome P450 Enzymes: Structure–Activity Relationships and Discovery Strategies To Mitigate Drug–Drug Interaction Risks
2012
VALIDATED ASSAYS FOR HUMAN CYTOCHROME P450 ACTIVITIES
2004
Synthesis of silver nanoparticles using leaves of Catharanthus roseus Linn. G. Don and their antiplasmodial activities
2012 Standout
Contribution of Amine Oxidases to the Metabolism of Xenobiotics
1994
Dirithromycin increases ethinyl estradiol clearance without allowing ovulation
1995
Diagnosis and Treatment of Polycystic Ovary Syndrome: An Endocrine Society Clinical Practice Guideline
2013 Standout
Pharmacokinetics of Haloperidol
1989
Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs
2007 Standout
Evaluation of Various Dissolution Media for Predicting In Vivo Performance of Class I and II Drugs
1998 Standout
Targeting multidrug resistance in cancer
2006 Standout
Lymphatic Transport of Halofantrine in the Conscious Rat When Administered as Either the Free Base or the Hydrochloride Salt: Effect of Lipid Class and Lipid Vehicle Dispersion
1996
Clinical Pharmacokinetics and Pharmacodynamics of Tacrolimus in Solid Organ Transplantation
2004 Standout
Dipeptide Derivatives of Primaquine as Transmission-Blocking Antimalarials: Effect of Aliphatic Side-Chain Acylation on the Gametocytocidal Activity and on the Formation of Carboxyprimaquine in Rat Liver Homogenates
1999
Methemoglobinemia: Etiology, Pharmacology, and Clinical Management
1999 Standout
Lymphatic Transport of Halofantrine in the Triple-Cannulated Anesthetized Rat Model: Effect of Lipid Vehicle Dispersion
1996
Drug-protein conjugates—XIV
1988
Evidence that certain 8-aminoquinolines are potentially effective drugs against Chagas disease
1997
Effects of Rifabutin and Rifampicin on the Pharmacokinetics of Ethinylestradiol and Norethindrone
1998
Absorption of Danazol After Administration to Different Sites of the Gastrointestinal Tract and the Relationship to Single‐ and Double‐Peak Phenomena in the Plasma Profiles
1993
The lack of interaction between temafloxacin and combined oral contraceptive steroids
1991
Pharmacokinetic and Pharmacodynamic Issues in the Treatment of Parasitic Infections
2004
Severe Adverse Cutaneous Reactions to Drugs
1994 Standout
Intestinal lymphatic drug transport: an update
2001
Pharmacokinetics of Haloperidol
1999
Primaquine revisited six decades after its discovery
2008
Drug interaction studies between paclitaxel (Taxol) and OC144-093 — A new modulator of MDR in cancer chemotherapy
2002
Enzyme induction in the cytochrome P-450 system
1990 Standout
Polycystic ovary syndrome
2016 Standout
Extrahepatic Metabolism of Drugs in Humans
1994
Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation
2013 Standout
Oral contraceptive failure rates and oral antibiotics
1997
Absence of Pharmacokinetic Interactions of the Combined Contraceptive Vaginal Ring NuvaRing?? with Oral Amoxicillin or Doxycycline in Two Randomised Trials
2005
Severe falciparum malaria
2000
Imidazolidin-4-one peptidomimetic derivatives of primaquine: Synthesis and antimalarial activity
2008
Severe falciparum malaria
2004 Standout
Antipyrine as a model drug to study hepatic drug-metabolizing capacity
1988
Piperaquine
2005
Oral Contraception Does Not Alter Single Dose Saquinavir Pharmacokinetics in Women
2004
Human Cannabinoid Pharmacokinetics
2007 Standout
Effect of Food and a Monoglyceride Emulsion Formulation on Danazol Bioavailability
1993
Antimalarial Drug Toxicity
2004
U.S. Medical Eligibility Criteria for Contraceptive Use, 2010
2011
Clinical Pharmacokinetics of Antimalarial Drugs
1985
Drug−Protein Adducts: An Industry Perspective on Minimizing the Potential for Drug Bioactivation in Drug Discovery and Development
2003
Tumour stem cells and drug resistance
2005 Standout
Effect of oral contraceptive steroids on the clinical course of malaria infection and on the pharmacokinetics of mefloquine in Thai women.
1988
Comparison of Five In Vitro Digestion Models To Study the Bioaccessibility of Soil Contaminants
2002 Standout
A Critical Review on Chagas Disease Chemotherapy
2002 Standout
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
Prediction of Drug Absorption Using Multivariate Statistics
2000 Standout
Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients With COVID-19 (April 2020)
2020 Standout
Pharmacokinetics of oral contraceptive steroids following the administration of the antimalarial drugs primaquine and chloroquine
1984
Imidazolidin-4-one Derivatives of Primaquine as Novel Transmission-Blocking Antimalarials
2005
Sex determination and sex differentiation in fish: an overview of genetic, physiological, and environmental influences
2002 Standout
Role of Pharmacokinetics and Metabolism in Drug Discovery and Development
1997
Transport of lipophilic molecules by the intestinal lymphatic system
1991
The Many Roles for Fluorine in Medicinal Chemistry
2008 Standout
An investigation of the role of metabolism in dapsone‐induced methaemoglobinaemia using a two compartment in vitro test system.
1990
Formulation design and bioavailability assessment of lipidic self-emulsifying formulations of halofantrine
1998
Metabolism-guided drug design
2012
Uptake and activity of rifapentine in human peritoneal macrophages and polymorphonuclear leukocytes
1987
The effect of enzyme inhibition on the metabolism and activation of tacrine by human liver microsomes.
1994
U.S. Medical Eligibility Criteria for Contraceptive Use, 2016
2016 Standout
Direct and metabolism‐dependent toxicity of sulphasalazine and its principal metabolites towards human erythrocytes and leucocytes.
1991
Subcellular Partitioning and Intramacrophage Selectivity of Antimicrobial Compounds against Mycobacterium tuberculosis
2017 StandoutNobel
Differences in the cytochrome P-450 isoenzymes involved in the 2-hydroxylation of oestradiol and 17 α-ethinyloestradiol. Relative activities of rat and human liver enzymes
1990
Clinical Implications of Enzyme Induction and Enzyme Inhibition
1981
Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray.
2002 Standout
Insecticide-treated bed nets and curtains for preventing malaria
2004 Standout
Antinociceptive action of nitrous oxide is mediated by stimulation of noradrenergic neurons in the brainstem and activation of [alpha]2B adrenoceptors.
2000 StandoutNobel
Efficacy of Diethylcarbamazine in Eradicating Infection with Lymphatic-Dwelling Filariae in Humans
1985
Structural Alert/Reactive Metabolite Concept as Applied in Medicinal Chemistry to Mitigate the Risk of Idiosyncratic Drug Toxicity: A Perspective Based on the Critical Examination of Trends in the Top 200 Drugs Marketed in the United States
2011
Phytochemical Screening and Antioxidant Activities of Some Selected Medicinal Plants Used for Malaria Therapy in Southwestern Nigeria
2008 Standout
Macrolide Antibacterials
1995
Works of ML Orme being referenced
Pharmacokinetics of halofantrine in man: effects of food and dose size.
1989
The effect of variations in urinary pH on the pharmacokinetics of diethylcarbamazine.
1981
Pharmacokinetics of primaquine in man. I. Studies of the absolute bioavailability and effects of dose size.
1985
Evaluation of Committee on Safety of Medicines yellow card reports on oral contraceptive‐drug interactions with anticonvulsants and antibiotics.
1988
The effects of food on drug bioavailability.
1989
Effect of chloroquine and primaquine on antipyrine metabolism.
1983
The effect of moderate urine alkalinisation on low dose diethylcarbamazine therapy in patients with onchocerciasis.
1986
The metabolism of 17 alpha‐ethinyloestradiol by human liver microsomes: formation of catechol and chemically reactive metabolites.
1987
Antibacterial activity in serum and urine following oral administration in man of DL473 (a cyclopentyl derivative of rifampicin) [proceedings]
1978
Intestinal metabolism of ethinyloestradiol and paracetamol in vitro: studies using Ussing chambers.
1987
Tolbutamide 4‐hydroxylase activity of human liver microsomes: effect of inhibitors.
1987
Pharmacokinetics of primaquine in man: identification of the carboxylic acid derivative as a major plasma metabolite.
1984