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Nonviral Vectors for Gene Delivery
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1987
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2009
Absence of functional lymphatics within a murine sarcoma: a molecular and functional evaluation.
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2007
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Cyclodextrin Drug Carrier Systems
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Network of dendritic cells within the muscular layer of the mouse intestine
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Folding of a donor–acceptor polyrotaxane by using noncovalent bonding interactions
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1999
Clinical experiences with magnetic drug targeting: a phase I study with 4'-epidoxorubicin in 14 patients with advanced solid tumors.
1996
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2000
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2006
Novel Branched Poly(Ethylenimine)−Cholesterol Water-Soluble Lipopolymers for Gene Delivery
2002
Improved transdermal delivery of prostaglandin E1 through hairless mouse skin: combined use of carboxymethyl-ethyl-β-cyclodextrin and penetration enhancers
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Carbon Nanomaterials for Biological Imaging and Nanomedicinal Therapy
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Multistage nanoparticle delivery system for deep penetration into tumor tissue
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Gene Disruption of Tissue Transglutaminase
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2008 StandoutNobel
Transgenic Mice Expressing a Mutant Form of Loricrin Reveal the Molecular Basis of the Skin Diseases, Vohwinkel Syndrome and Progressive Symmetric Erythrokeratoderma
2000
In Vitro and in Vivo mRNA Delivery Using Lipid-Enveloped pH-Responsive Polymer Nanoparticles
2011
The Role of the Size and Number of Polyethylene Glycol Chains in the Biodistribution and Tumor Localization of Triazine Dendrimers
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Steric Stabilization of poly-l -Lysine/DNA Complexes by the Covalent Attachment of Semitelechelic poly[N-(2-Hydroxypropyl)methacrylamide]
2000
Novel Strategies to Improve the Anticancer Action of 5-Fluorouracil by Using Drug Delivery Systems
2008
In vivo hematopoietic stem cell modification by mRNA delivery
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TAPping into mRNA Export
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Key issues in non-viral gene delivery
1998
Targeted Ablation of the Murine Involucrin Gene
2000
Radioactive liposomes
2008
Poly(DMAEMA-NVP)-b-PEG-galactose as Gene Delivery Vector for Hepatocytes
2000
Designing Macromolecules for Therapeutic Applications: Polyester DendrimerPoly(ethylene oxide) “Bow-Tie” Hybrids with Tunable Molecular Weight and Architecture
2002
Magnetic Nanoparticles: Design and Characterization, Toxicity and Biocompatibility, Pharmaceutical and Biomedical Applications
2012 Standout
The Fluorescent Toolbox for Assessing Protein Location and Function
2006 StandoutScienceNobel
Poly(glycoamidoamine)s for Gene Delivery: Stability of Polyplexes and Efficacy with Cardiomyoblast Cells
2005
Chemodynamic Therapy: Tumour Microenvironment‐Mediated Fenton and Fenton‐like Reactions
2018 Standout
Effect of 2-Hydroxypropyl-β-cyclodextrin on Percutaneous Absorption of Methyl Paraben
1995
Cathepsin D is involved in the regulation of transglutaminase 1 and epidermal differentiation
2004
Improved Drug Delivery Through the Skin by Hydrophilic β-Cyclodextrins
1990
Dendrimers Designed for Functions: From Physical, Photophysical, and Supramolecular Properties to Applications in Sensing, Catalysis, Molecular Electronics, Photonics, and Nanomedicine
2010 Standout
Dexamethasone-Conjugated Low Molecular Weight Polyethylenimine as a Nucleus-Targeting Lipopolymer Gene Carrier
2007
Superparamagnetic iron oxide nanoparticles: from preparations to in vivo MRI applications
2009
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Dendrimers in Oncology: An Expanding Horizon
2008
Claudin-based tight junctions are crucial for the mammalian epidermal barrier
2002 Standout
Photopharmacology: Beyond Proof of Principle
2014 StandoutNobel
pH-Responsive Three-Layered PEGylated Polyplex Micelle Based on a Lactosylated ABC Triblock Copolymer as a Targetable and Endosome-Disruptive Nonviral Gene Vector
2006
Polyethylenimine-graft-Poly(ethylene glycol) Copolymers: Influence of Copolymer Block Structure on DNA Complexation and Biological Activities as Gene Delivery System
2002
Water-Soluble Lipopolymer for Gene Delivery
2001
Fast detection of liver fibrosis with collagen-binding single-nanometer iron oxide nanoparticles via T 1 -weighted MRI
2023 StandoutNobel
Effects of β-cyclodextrins on skin: implications for the transdermal delivery of piribedil and a novel cognition enhancing-drug, S-9977
1995
Biodegradable Poly(ethylene glycol)-co-poly(l -lysine)-g-histidine Multiblock Copolymers for Nonviral Gene Delivery
2004
Combination effects of O-carboxymethyl-O-ethyl-β-cyclodextrin and penetration enhancer HPE-101 on transdermal delivery of prostaglandin E1 in hairless mice
1993
PEGylated Dendrimers with Core Functionality for Biological Applications
2008
Synthesis and Characterization of Dextran−Peptide−Methotrexate Conjugates for Tumor Targeting via Mediation by Matrix Metalloproteinase II and Matrix Metalloproteinase IX
2004
Mechanism of cell death induced by cationic dendrimers in RAW 264.7 murine macrophage-like cells
2005
Synthesis of new unsymmetrical optically active (s)-(+)-naproxen dendrimers
2004
Works of Mitsuru Hashida being referenced
Disposition of oligonucleotides in isolated perfused rat kidney: involvement of scavenger receptors in their renal uptake.
1996
In Silico Approaches for Predicting ADME Properties of Drugs
2004
Cell-specific delivery of genes with glycosylated carriers
2001
Effect of Cationic Liposomes on Intracellular Trafficking and Efficacy of Antisense Oligonucleotides in Mouse Peritoneal Macrophages
1999
Hepatic uptake of polystyrene microspheres in rats: Effect of particle size on intrahepatic distribution
1999
Effects of erythrocytes and serum proteins on lung accumulation of lipoplexes containing cholesterol or DOPE as a helper lipid in the single-pass rat lung perfusion system
2001
Therapeutic effects of superoxide dismutase derivatives modified with mono- or polysaccharides on hepatic injury induced by ischemia/reperfusion
1992
Gene expression and antitumor effects following direct interferon (IFN)-γ gene transfer with naked plasmid DNA and DC-chol liposome complexes in mice
1999
Biodistribution characteristics of amino acid dendrimers and their PEGylated derivatives after intravenous administration
2006
Control of Pharmaceutical Properties of Soybean Trypsin Inhibitor by Conjugation with Dextran II: Biopharmaceutical and Pharmacological Properties
1989
Renal press-mediated transfection method for plasmid DNA and siRNA to the kidney
2008
Inhibition of liver metastasis by targeting of immunomodulators using mannosylated liposome carriers
2002
Control ofIn VivoFate of Albumin Derivatives Utilizing Combined Chemical Modification
1994
Factors Affecting Drug and Gene Delivery: Effects of Interaction with Blood Components
2002
Uptake and Gene Expression of Naked Plasmid DNA in Cultured Brain Microvessel Endothelial Cells
1998
Development of Targeted Delivery Systems for Nucleic Acid Drugs
1997
Percutaneous Penetration of Acyclovir Through Excised Hairless Mouse and Rat Skin: Effect of Vehicle and Percutaneous Penetration Enhancer
1990
Efficient targeting to alveolar macrophages by intratracheal administration of mannosylated liposomes in rats
2007
Efficient peritoneal dissemination treatment obtained by an immunostimulatory phosphorothioate-type CpG DNA/cationic liposome complex in mice
2007
Optimization of tumor-selective targeting by basic fibroblast growth factor-binding peptide grafted PEGylated liposomes
2007
Prevention of pulmonary metastasis from subcutaneous tumors by binary system-based sustained delivery of catalase
2009
Control of Pharmaceutical Properties of Soybean Trypsin Inhibitor by Conjugation with Dextran I: Synthesis and Characterization
1989
Inhibition of experimental pulmonary metastasis by controlling biodistribution of catalase in mice
2002
Intravenous fate of poly(2-(dimethylamino)ethyl methacrylate)-based polyplexes
2003
Biliary excretion of polystyrene microspheres depends on the type of receptor-mediated uptake in rat liver
2001
PEGylated lysine dendrimers for tumor-selective targeting after intravenous injection in tumor-bearing mice
2006
Intravenous administration of mannosylated cationic liposome/NFκB decoy complexes effectively prevent LPS‐induced cytokine production in a murine liver failure model
2006
Disposition characteristics of plasmid DNA in the single-pass rat liver perfusion system.
1996
Use of mannosylated cationic liposomes/ immunostimulatory CpG DNA complex for effective inhibition of peritoneal dissemination in mice
2008
The role of dioleoylphosphatidylethanolamine (DOPE) in targeted gene delivery with mannosylated cationic liposomes via intravenous route
2005
The fate of poly(2-dimethyl amino ethyl)methacrylate-based polyplexes after intravenous administration
2001
Macromolecular drug carrier systems in cancer chemotherapy: macromolecular prodrugs
1995
Small interfering RNA delivery to the liver by intravenous administration of galactosylated cationic liposomes in mice
2006
Physicochemical and Pharmacokinetic Characteristics of Plasmici DNA/ Cationic Liposome Complexes
1995
Hepatocyte-targeted in vivo gene expression by intravenous injection of plasmid DNA complexed with synthetic multi-functional gene delivery system
2000
Macromolecular Carrier Systems for Targeted Drug Delivery: Pharmacokinetic Considerations on Biodistribution
1996
Disposition Characteristics of Macromolecules in Tumor-Bearing Mice
1990
Plasmid DNA activates murine macrophages to induce inflammatory cytokines in a CpG motif-independent manner by complex formation with cationic liposomes
2002
Uptake by Hepatocytes and Biliary Excretion of Intravenously Administered Polystyrene Microspheres in Rats
1999
In Vivo Disposition Characteristics of Plasmid DNA Complexed with Cationic Liposomes
1995
Glycosylated Cationic Liposomes for Carbohydrate Receptor–Mediated Gene Transfer
2003
Novel PEG-matrix metalloproteinase-2 cleavable peptide-lipid containing galactosylated liposomes for hepatocellular carcinoma-selective targeting
2006
Self-assemble gene delivery system for molecular targeting using nucleic acid aptamer
2011
Evaluation of Proinflammatory Cytokine Production Induced by Linear and Branched Polyethylenimine/Plasmid DNA Complexes in Mice
2006
Influence of Physicochemical Properties on Pharmacokinetics of Non-viral Vectors for Gene Delivery
2002
Biodistribution characteristics of mannosylated, fucosylated, and galactosylated liposomes in mice
2000
Photodynamic and Photothermal Effects of Semiconducting and Metallic-Enriched Single-Walled Carbon Nanotubes
2012
Targeted delivery of plasmid DNA complexed with galactosylated poly(l-lysine)
1998
Luminescent proteins for high-speed single-cell and whole-body imaging
2012
Development of Nitric Oxide Donors for the Treatment of Cardiovascular Diseases
2007
Enhanced Anti-Inflammation of Inhaled Dexamethasone Palmitate Using Mannosylated Liposomes in an Endotoxin-Induced Lung Inflammation Model
2008
Effect of Particle Size and Charge on the Disposition of Lipid Carriers After Intratumoral Injection into Tissue-isolated Tumors
1998
The 4F2hc/LAT1 complex transports l-DOPA across the blood–brain barrier
2000
Molecular weight-dependent gene transfection activity of unmodified and galactosylated polyethyleneimine on hepatoma cells and mouse liver
2003
Pharmacokinetic Evaluation of Mannosylated Bovine Serum Albumin as a Liver Cell-Specific Carrier: Quantitative Comparison with Other Hepatotropic Ligands
1999
Mannose receptor-mediated gene transfer into macrophages using novel mannosylated cationic liposomes
2000
Enhanced Transfection Efficiency into Macrophages and Dendritic Cells by a Combination Method Using Mannosylated Lipoplexes and Bubble Liposomes with Ultrasound Exposure
2009
Immunostimulatory Characteristics Induced by Linear Polyethyleneimine–Plasmid DNA Complexes in Cultured Macrophages
2009
Defective stratum corneum and early neonatal death in mice lacking the gene for transglutaminase 1 (keratinocyte transglutaminase)
1998
Pharmacokinetics of anticancer drugs, plasmid DNA, and their delivery systems in tissue-isolated perfused tumors
1999
Effects of β-cyclodextrin and di-O-methyl-β-cyclodextrin on the percutaneous absorption of butylparaben, indomethacin and sulfanilic acid
1986
Absorption characteristics of the lipophilic prodrug of mitomycin C from injected liposomes or an emulsion
1985
Soluble macromolecular carriers for the delivery of antitumour drugs
1989
Pharmacokinetics in design of polymeric drug delivery systems
1994
Characterization of alkylcarbamoyl derivatives of 5-fluorouracil and their application to liposome
1987
Antitumor activity of mitomycin C-dextran conjugate against various murine tumors.
1981
A new method for assessment of drug disposition in muscle: Application of statistical moment theory to local perfusion systems
1985
Enhanced Gene Transfection in Macrophages by Histidine-Conjugated Mannosylated Cationic Liposomes
2009
Suppression of Melanoma Growth and Metastasis by DNA Vaccination Using an Ultrasound-Responsive and Mannose-Modified Gene Carrier
2011
Preservative activity and in vivo percutaneous penetration of butylparaben entrapped in liposomes.
1986
Hepatic Uptake and Gene Expression Mechanisms following Intravenous Administration of Plasmid DNA by Conventional and Hydrodynamics-Based Procedures
2001
The Accumulation Mechanism of Cationic Mitomycin C-dextran Conjugates in the Liver: In-vivo Cellular Localization and In-vitro Interaction with Hepatocytes
1988
Development of a novel polymeric prodrug of mitomycin C, mitomycin C-dextran conjugate with anionic charge. II. Disposition and pharmacokinetics following intravenous and intramuscular administration
1987
Experimental study on lymphatic vascular changes in the development of cancer.
1981
Control of pharmacokinetic profiles of drug—macromolecule conjugates
1996
Nonviral Approaches Satisfying Various Requirements for Effective in Vivo Gene Therapy.
2002
In vitro cytotoxicity of macromolecules in different cell culture systems
1995
Surgical chemotherapy against lymph node metastases: an experimental study.
1980
Characterization of Liposomes and an Emulsion Containing Mitomycin C or Lipophilic Mitomycin C Prodrugs
1986
Photothermic regulation of gene expression triggered by laser-induced carbon nanohorns
2012
Intratumoral pharmacokinetics and in vivo gene expression of naked plasmid DNA and its cationic liposome complexes after direct gene transfer.
1997
Pharmacokinetics andIn VivoGene Transfer of Plasmid DNA Complexed with Mannosylated Poly(L-Lysine) in Mice
2000
Pharmacokinetics and targeted delivery of proteins and genes
1996
Pharmacokinetic evaluation of polymeric carriers
1996
Nonviral Vectors for In Vivo Gene Delivery: Physicochemical and Pharmacokinetic Considerations
1997
Macromolecule-drug conjugates in targeted cancer chemotherapy.
1984
Targeted Delivery of Plasmid DNA to Hepatocytes In Vivo: Optimization of the Pharmacokinetics of Plasmid DNA/Galactosylated Poly(l-Lysine) Complexes by Controlling their Physicochemical Properties
1998
Enhanced lymphatic delivery of mitomycin C conjugated with dextran.
1984
Development of a novel polymeric prodrug of mitomycin C, mitomycin C-dextran conjugate with anionic charge. I. Physicochemical characteristics and in vivo and in vitro antitumor activities
1987
Percutaneous absorption of butylparaben from liposomes in vitro.
1986