Citation Impact
Citing Papers
Efficient biotinylation and single-step purification of tagged transcription factors in mammalian cells and transgenic mice
2003
Sequencing and Analysis of Neanderthal Genomic DNA
2006 StandoutScienceNobel
Induction of fetal hemoglobin synthesis by CRISPR/Cas9-mediated editing of the human β-globin locus
2018
ZBTB1 is a determinant of lymphoid development
2011 StandoutNobel
Four-component protein nanocages designed by programmed symmetry breaking
2024 StandoutNatureNobel
Notch signalling controls pancreatic cell differentiation
1999 StandoutNatureNobel
Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene.
1995
Editing of Cellular Self-RNAs by Adenosine Deaminase ADAR1 Suppresses Innate Immune Stress Responses
2016
Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL
1995 Nature
β-Catenin Controls Hair Follicle Morphogenesis and Stem Cell Differentiation in the Skin
2001 Standout
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
Mammalian conserved ADAR targets comprise only a small fragment of the human editosome
2014
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Long-Term Engraftment and Fetal Globin Induction upon BCL11A Gene Editing in Bone-Marrow-Derived CD34 + Hematopoietic Stem and Progenitor Cells
2017
Transcription factor GATA-3 is required for development of the T-cell lineage
1996 Nature
Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis
2013
AML1, the Target of Multiple Chromosomal Translocations in Human Leukemia, Is Essential for Normal Fetal Liver Hematopoiesis
1996 Standout
A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development
1997
ADAR1 Forms a Complex with Dicer to Promote MicroRNA Processing and RNA-Induced Gene Silencing
2013
Self-Assembling Drugs: A New Approach to Biochemical Modulation in Cancer Chemotherapy
1994
Stem Cells
2000
Flow cytometric identification and purification of cells by ligand-induced changes in intracellular calcium
1988
Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo
1999
Targeted Disruption of Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts
1997 Standout
Hemoglobin: Structure, Function and Allostery
2020
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
2018 StandoutNobel
RNA Binding-independent Dimerization of Adenosine Deaminases Acting on RNA and Dominant Negative Effects of Nonfunctional Subunits on Dimer Functions
2007
GATA3 haplo-insufficiency causes human HDR syndrome
2000 Nature
CRISPR-Cas9 interrogation of a putative fetal globin repressor in human erythroid cells
2019
Jak2 Deficiency Defines an EssentialDevelopmental Checkpoint in DefinitiveHematopoiesis
1998
A genome-wide comparison of recent chimpanzee and human segmental duplications
2005 StandoutNatureNobel
The Zinc Finger-containing Transcription Factors GATA-4, -5, and -6
2000
Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1
2007 StandoutNatureNobel
Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice
1995 StandoutNature
Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding
2018
Regulation of calcium influx by second messengers in rat mast cells
1988 StandoutNatureNobel
Molecular Events Mediating T Cell Activation
1990
Pattern recognition computation using action potential timing for stimulus representation
1995 StandoutNatureNobel
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
2017 StandoutNature
Crystal structure of Thermus aquaticus DNA polymerase
1995 StandoutNatureNobel
ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling
2008
The RNA-Editing Enzyme ADAR1 Controls Innate Immune Responses to RNA
2014
Cardiotrophin-1 and the role of gp130-dependent signaling pathways in cardiac growth and development
1997
Liver Disintegration in the Mouse Embryo Caused by Deficiency in the RNA-editing Enzyme ADAR1
2004
Mouse embryonic hematopoiesis
1995
Synergism through direct covalent bonding between agents: A strategy for rational design of chemotherapeutic combinations
1990
Reaction mechanism of alkaline phosphatase based on crystal structures
1991 Standout
Design of biologically active binary protein 2D materials
2021 StandoutNatureNobel
Photoinactivation of the bovine heart mitochondrial F1-ATPase by [14C]dequalinium crosslinks phenylalanine-403 or phenylalanine-406 of an .alpha. subunit to a site or sites contained within residues 440-459 of a .beta. subunit
1993
Mechanisms of thrombopoiesis
2005
Initial sequence of the chimpanzee genome and comparison with the human genome
2005 StandoutNature
Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins
2022
Isolation of mutant T lymphocytes with defects in capacitative calcium entry
1995
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
Transcription Factors and Hematopoietic Development
1995
Lymphohematopoietic development from embryonic stem cells in vitro
1995
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5
2003 StandoutNature
The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors
1997
GATA-4 Activates Transcription Via Two Novel Domains That Are Conserved within the GATA-4/5/6 Subfamily
1997
A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
2000 StandoutNature
Emptying of intracellular Ca2+ stores releases a novel small messenger that stimulates Ca2+ influx
1993 StandoutNatureNobel
The CBFβ Subunit Is Essential for CBFα2 (AML1) Function In Vivo
1996
Nascent-Seq Indicates Widespread Cotranscriptional RNA Editing in Drosophila
2012 StandoutNobel
Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis
1995
Jak2 Is Essential for Signaling through a Variety of Cytokine Receptors
1998 Standout
Analysis of one million base pairs of Neanderthal DNA
2006 StandoutNatureNobel
Eomesodermin is required for mouse trophoblast development and mesoderm formation
2000 StandoutNatureNobel
RNA-specific Adenosine Deaminase ADAR1 Suppresses Measles Virus-induced Apoptosis and Activation of Protein Kinase PKR
2009
Structure at 2.8 Â resolution of F1-ATPase from bovine heart mitochondria
1994 StandoutNatureNobel
The evolution of gene expression levels in mammalian organs
2011 StandoutNatureNobel
Modeling neurodevelopmental disorder-associated humanAGO1mutations inCaenorhabditis elegansArgonautealg-1
2024 StandoutNobel
Molecular Characterization of a Functional cDNA Encoding the Serotonin 1c Receptor
1988 StandoutScienceNobel
GATA4 transcription factor is required for ventral morphogenesis and heart tube formation.
1997
Isolation of Putative Progenitor Endothelial Cells for Angiogenesis
1997 StandoutScience
c-Myc–mediated control of cell fate in megakaryocyte-erythrocyte progenitors
2009
Functions and Regulation of RNA Editing by ADAR Deaminases
2010
Absence of fetal liver hematopoiesis in mice deficient in transcriptional coactivator core binding factor beta.
1996
In Vitro Development of Primitive and Definitive Erythrocytes from Different Precursors
1996 StandoutScienceNobel
Quantitation of Transcription and Clonal Selection of Single Living Cells with β-Lactamase as Reporter
1998 StandoutScienceNobel
Thy-1 functions as a signal transduction molecule in T lymphocytes and transfected B lymphocytes
1986 Nature
The zinc finger proteins Pannier and GATA4 function as cardiogenic factors in Drosophila
1999
Receptor-operated Ca channels
1987 StandoutNatureNobel
Consequences of GATA-1 Deficiency in Megakaryocytes and Platelets
1999
Transcription Factors, Normal Myeloid Development, and Leukemia
1997
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
1997 Standout
Parallel Patterns of Evolution in the Genomes and Transcriptomes of Humans and Chimpanzees
2005 StandoutScienceNobel
Single-channel and whole-cell recordings of mitogen-regulated inward currents in human cloned helper T lymphocytes
1986 Nature
Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis.
1997
Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1.
1996
Bone matrix mRNA expression in differentiating fetal bovine osteoblasts
1992
Ion channels activated by specific Ti or T3 antibodies in plasma membranes of human T cells.
1987
Ectopic Expression of the Serotonin 1c Receptor and the Triggering of Malignant Transformation
1989 StandoutScienceNobel
Ion channels activated by inositol 1,4,5-trisphosphate in plasma membrane of human T-lymphocytes
1987 Nature
Excavating Neandertal and Denisovan DNA from the genomes of Melanesian individuals
2016 StandoutScienceNobel
Lethal β-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF
1995 Nature
Pleiotropic loss of activation pathways in a T-cell receptor α-chain deletion variant of a cytolytic T-cell clone
1987 StandoutNatureNobel
Multilineage gene expression precedes commitment in the hemopoietic system.
1997
Ribonuclease L mediates the cell-lethal phenotype of double-stranded RNA editing enzyme ADAR1 deficiency in a human cell line
2017
Thrombopoietin rescues in vitro erythroid colony formation from mouse embryos lacking the erythropoietin receptor.
1996
RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself
2015 Science
DrosophilaMushroom Body Mutants are Deficient in Olfactory Learning
1985
Disruption of the mouse RBP-Jк gene results in early embryonic death
1995 StandoutNobel
Odorant-induced oscillations in the mushroom bodies of the locust
1994
TRANSCRIPTION OF EUKARYOTIC PROTEIN-CODING GENES
2000
Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells
2010 StandoutNobel
Human embryonic stem cells differentiate into a homogeneous population of natural killer cells with potent in vivo antitumor activity
2009
Mr 26,000 antigen of Schistosoma japonicum recognized by resistant WEHI 129/J mice is a parasite glutathione S-transferase.
1986
Erythropoietin crosses the blood–brain barrier to protect against experimental brain injury
2000 Standout
Widespread A-to-I RNA Editing of Alu-Containing mRNAs in the Human Transcriptome
2004
Structure, Function, and Serology of the T-Cell Antigen Receptor Complex
1987 StandoutNobel
The Mating of a Fly
1994 StandoutScienceNobel
Developmentally ordered appearance of thymocytes expressing different T-cell antigen receptors
1988 StandoutNatureNobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution
2001 StandoutScienceNobel
Consequences of GATA-1 Deficiency in Megakaryocytes and Platelets
1999
Enhancement of Replication of RNA Viruses by ADAR1 via RNA Editing and Inhibition of RNA-Activated Protein Kinase
2011
Regulation of the Ets-Related Transcription Factor Elf-1 by Binding to the Retinoblastoma Protein
1993 StandoutScienceNobel
Engineering Chemical Reactivity on Cell Surfaces Through Oligosaccharide Biosynthesis
1997 StandoutScienceNobel
A natural regulatory mutation in the proximal promoter elevates fetal globin expression by creating a de novo GATA1 site
2019
Analysis of the Thy‐1 pathway of T cell hybridoma activation using 17 rat monoclonal antibodies reactive with distinct Thy‐1 epitopes
1985
Transcription Factors, Normal Myeloid Development, and Leukemia
1997
Works of Mitchell J. Weiss being referenced
An early haematopoietic defect in mice lacking the transcription factor GATA-2
1994 Nature
Stress-induced Apoptosis Associated with Null Mutation of ADAR1 RNA Editing Deaminase Gene
2004
Self-Renewing Endodermal Progenitor Lines Generated from Human Pluripotent Stem Cells
2012
Neuronal connections and the function of the corpora pedunculata in the brain of the American cockroach, Periplaneta americana (L.)
1974
Chromothripsis as an on-target consequence of CRISPR–Cas9 genome editing
2021
Global Predictions and Tests of Erythroid Regulatory Regions
2003
FOG, a Multitype Zinc Finger Protein, Acts as a Cofactor for Transcription Factor GATA-1 in Erythroid and Megakaryocytic Differentiation
1997
Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression
2009
STAT1 promotes megakaryopoiesis downstream of GATA-1 in mice
2007
In vitro differentiation of murine embryonic stem cells. New approaches to old problems.
1996
A genome-editing strategy to treat β-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition
2016
LRF Is an Essential Downstream Target of GATA1 in Erythroid Development and Regulates BIM-Dependent Apoptosis
2009
Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1
2000
Hemoglobin Variants: Biochemical Properties and Clinical Correlates
2013
CREB-Binding Protein Acetylates Hematopoietic Transcription Factor GATA-1 at Functionally Important Sites
1999
GATA-1 and Erythropoietin Cooperate to Promote Erythroid Cell Survival by Regulating bcl-xL Expression
1999
A missense mutation in the human liver/bone/kidney alkaline phosphatase gene causing a lethal form of hypophosphatasia.
1988
Dequalinium, a topical antimicrobial agent, displays anticarcinoma activity based on selective mitochondrial accumulation.
1987
Structural patterns in the corpora pedunculata of orthoptera: A reduced silver analysis
1981
The T11 glycoprotein is functionally linked to a calcium channel in precursor and mature T-lineage cells.
1986
GATA-1-Mediated Proliferation Arrest during Erythroid Maturation
2003
Selective killing of carcinoma cells "in vitro" by lipophilic-cationic compounds: a cellular basis.
1985
Mitochondrial and plasma membrane potentials cause unusual accumulation and retention of rhodamine 123 by human breast adenocarcinoma-derived MCF-7 cells.
1985
Closing and sequence analysis of a cDNA plasmid for one of the rat liver glutathione S-transferase subunits
1982
A GATA-1-regulated microRNA locus essential for erythropoiesis
2008
Designer blood: creating hematopoietic lineages from embryonic stem cells
2005
Isolation and characterization of a cDNA encoding a human liver/bone/kidney-type alkaline phosphatase.
1986
cDNA cloning of alkaline phosphatase from rat osteosarcoma (ROS 17/2.8) cells
1987
Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells.
1994
Calcium dependency of antigen-specific (T3-Ti) and alternative (T11) pathways of human T-cell activation.
1984
GATA transcription factors: key regulators of hematopoiesis.
1995
Transcription factor GATA-1 permits survival and maturation of erythroid precursors by preventing apoptosis.
1995
Erythroid-Cell-Specific Properties of Transcription Factor GATA-1 Revealed by Phenotypic Rescue of a Gene-Targeted Cell Line
1997