Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica
2008 StandoutScience
Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression
2013 StandoutNobel
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
2007 Standout
Combined salmeterol and fluticasone in the treatment of chronic obstructive pulmonary disease: a randomised controlled trial
2003
Early onset of effect of salmeterol and fluticasone propionate in chronic obstructive pulmonary disease
2005
Assessment of the Economic Burden of COPD in the U.S.: A Review and Synthesis of the Literature
2006
Expression of connective tissue growth factor in experimental rat and human liver fibrosis
1999
Bronchodilating Effects of Combined Therapy With Clinical Dosages of Ipratropium Bromide and Salbutamol for Stable COPD:
1995
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
A Pilot Study of Aerosolized Amiloride for the Treatment of Lung Disease in Cystic Fibrosis
1990
The Role of Neural Inflammation in Asthma and Chronic Obstructive Pulmonary Disease
2003
Pharmacoeconomic Evaluation of Acute Exacerbations of Chronic Bronchitis and COPD
2002
Susceptibility to Exacerbation in Chronic Obstructive Pulmonary Disease
2010 Standout
Acute and Long-term Amiloride Inhalation in Cystic Fibrosis Lung Disease: A Rational Approach to Cystic Fibrosis Therapy
1990
Actions and interactions of high pressure and general anaesthetics
1988
Telomerase Mutations in Families with Idiopathic Pulmonary Fibrosis
2007 StandoutNobel
Generation and characterization of a ΔF508 cystic fibrosis mouse model
1995 StandoutNobel
Management of Chronic Obstructive Pulmonary Disease
2004
Use of Spirometry for Case Finding, Diagnosis, and Management of Chronic Obstructive Pulmonary Disease (COPD): Evidence Report/Technology Assessment, Number 121
2005
Comparison of tiotropium once daily, formoterol twice daily and both combined once daily in patients with COPD
2005
Increased Mortality Associated with Growth Hormone Treatment in Critically Ill Adults
1999
Long-term Treatment Benefits With Tiotropium in COPD Patients With and Without Short-term Bronchodilator Responses
2003
Liver fibrosis – from bench to bedside
2003 Standout
The Body-Mass Index, Airflow Obstruction, Dyspnea, and Exercise Capacity Index in Chronic Obstructive Pulmonary Disease
2004 Standout
Standardisation of the single-breath determination of carbon monoxide uptake in the lung
2005 Standout
Effect of salmeterol on respiratory muscle activity during exercise in poorly reversible COPD
2004
A randomised controlled comparison of tiotropium and ipratropium in the treatment of chronic obstructive pulmonary disease
2000
Depletion of Tumor-Associated Macrophages Slows the Growth of Chemically Induced Mouse Lung Adenocarcinomas
2014
Maintenance therapy with budesonide and formoterol in chronicobstructive pulmonary disease
2003
Global Initiative for Chronic Obstructive Lung Disease
2002 Standout
The Economic Burden of COPD
2000
Severe acute exacerbations and mortality in patients with chronic obstructive pulmonary disease
2005 Standout
Effects of tiotropium on lung hyperinflation, dyspnoea and exercise tolerance in COPD
2004
Chronic obstructive pulmonary disease
2003
Transcriptional Coactivator with PDZ-binding Motif Is Essential for Normal Alveolarization in Mice
2009
Superiority of "triple" therapy with salmeterol/fluticasone propionate and tiotropium bromide versus individual components in moderate to severe COPD
2008
Matrilysin Shedding of Syndecan-1 Regulates Chemokine Mobilization and Transepithelial Efflux of Neutrophils in Acute Lung Injury
2002
Molecular and cellular mechanisms of general anaesthesia
1994 StandoutNature
COPD exacerbations: defining their cause and prevention
2007
Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer
2015 Standout
Air pollution: mechanisms of neuroinflammation and CNS disease
2009 Standout
Costs of Chronic Obstructive Pulmonary Disease in Spain: Estimation From a Population-Based Study
2004
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Regulation of PDGF and its receptors in fibrotic diseases
2004
Improvement in self-reported exercise participation with the combination of tiotropium and rehabilitative exercise training in COPD patients
2008
Molecular and functional properties of lung SP cells
2006
Hypoxia induces endothelin gene expression and secretion in cultured human endothelium.
1991
Phosphorylated Akt overexpression and loss of PTEN expression in non-small cell lung cancer confers poor prognosis
2005
Prenatal Exposure to Ozone Disrupts Cerebellar Monoamine Contents in Newborn Rats
2007
Bronchodilator reversibility testing in chronic obstructive pulmonary disease
2003
Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis
2006
The development of allergic inflammation
2008 StandoutNature
Autophagy in the Pathogenesis of Disease
2008 Standout
Pooled Clinical Trial Analysis of Tiotropium Safety
2006
Costs of Chronic Bronchitis and COPDa
2003
The role of the nervous system in rhinitis
2006
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
2010 Standout
Ozone and Pulmonary Innate Immunity
2007
A long-term prospective assessment of home nebulizer treatment
1992
Purification and Characterization of Hypoxia-inducible Factor 1
1995 StandoutNobel
Hypoxia modulates the barrier and coagulant function of cultured bovine endothelium. Increased monolayer permeability and induction of procoagulant properties.
1990
Effects of different concentrations of oxygen – ozone on rats’ astrocytes in vitro
2008
Angiotensin-converting enzyme 2 protects from severe acute lung failure
2005 StandoutNature
A long-term evaluation of once-daily inhaled tiotropium in chronic obstructive pulmonary disease
2002
Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues
2008 Standout
Sensory Nerves in Lung and Airways
2014
Body composition and mortality in chronic obstructive pulmonary disease
2005
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
Regulatory Functions of the Vascular Endothelium
1990 StandoutNobel
Exacerbations of chronic obstructive pulmonary disease
2007
Cystic fibrosis: molecular biology and therapeutic implications
1992 StandoutScience
One-year analysis of longitudinal changes in spirometry in patients with COPD receiving tiotropium
2004
Epidemiology and costs of chronic obstructive pulmonary disease
2005
Improved health outcomes in patients with COPD during 1 yr's treatment with tiotropium
2002
Non–invasive liposome–mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice
1993
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
The Efficacy and Safety of Fluticasone Propionate (250 μg)/Salmeterol (50 μg) Combined in the Diskus Inhaler for the Treatment of COPD
2003
Adenovirus-mediated HIF-1α gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection
2011 StandoutNobel
Health outcomes following treatment for six months with once daily tiotropium compared with twice daily salmeterol in patients with COPD
2003
Salmeterol and Fluticasone Propionate and Survival in Chronic Obstructive Pulmonary Disease
2007 Standout
Costs of COPD in Sweden According to Disease Severity
2002
The Nature of Small-Airway Obstruction in Chronic Obstructive Pulmonary Disease
2004 Standout
TRPA1 Mediates the Inflammatory Actions of Environmental Irritants and Proalgesic Agents
2006 StandoutNobel
Nitric oxide regulates the expression of vasoconstrictors and growth factors by vascular endothelium under both normoxia and hypoxia.
1993
A Short-Term Comparison of Fluticasone Propionate/Salmeterol with Ipratropium Bromide/Albuterol for the Treatment of COPD
2004
Piezo2 senses airway stretch and mediates lung inflation-induced apnoea
2016 StandoutNatureNobel
Skeletal muscle dysfunction in chronic obstructive pulmonary disease and chronic heart failure: underlying mechanisms and therapy perspectives
2000
Hypoxia and Mitochondrial Inhibitors Regulate Expression of Glucose Transporter-1 via Distinct Cis-acting Sequences
1995 StandoutNobel
A mouse model for the delta F508 allele of cystic fibrosis.
1995 StandoutNobel
Insulin/IGF signaling drives cell proliferation in part via Yorkie/YAP
2012
Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice
2007 StandoutNobel
Carbon Monoxide and Nitric Oxide Suppress the Hypoxic Induction of Vascular Endothelial Growth Factor Gene via the 5′ Enhancer
1998 StandoutNobel
Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy
1993 StandoutNatureNobel
Global burden of COPD: risk factors, prevalence, and future trends
2007 Standout
Tiotropium (SPIRIVA™): Mechanistical considerations and clinical profile in obstructive lung disease
1999
Intensive Insulin Therapy in Critically Ill Patients
2001 Standout
A 4-Year Trial of Tiotropium in Chronic Obstructive Pulmonary Disease
2008 Standout
The role of interleukin-2 during homeostasis and activation of the immune system
2012
Formoterol and Tiotropium Compared With Tiotropium Alone for Treatment of COPD
2009
Increased Phosphorylated Extracellular Signal-Regulated Kinase Immunoreactivity Associated with Proliferative and Morphologic Lung Alterations after Chrysotile Asbestos Inhalation in Mice
2000
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
2001 Standout
Clinical and Pathologic Features of Familial Interstitial Pneumonia
2005
Inhaled Formoterol Dry Powder Versus Ipratropium Bromide in Chronic Obstructive Pulmonary Disease
2001
Prognostic Value of Nutritional Status in Chronic Obstructive Pulmonary Disease
1999 Standout
Administration of Growth Hormone to Underweight Patients with Chronic Obstructive Pulmonary Disease
1997
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
2012 Standout
Effectiveness of Fluticasone Propionate and Salmeterol Combination Delivered via the Diskus Device in the Treatment of Chronic Obstructive Pulmonary Disease
2002
Interactions of oxygen radicals with airway epithelium.
1994
General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia.
1993 StandoutNobel
IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice
2007
Costes de la EPOC en España. Estimación a partir de un estudio epidemiológico poblacional
2004
Fluid and electrolyte transport by cultured human airway epithelia.
1993
Hazardous air pollutants and asthma.
2002
Hypoxia-inducible Factor-1 Mediates Transcriptional Activation of the Heme Oxygenase-1 Gene in Response to Hypoxia
1997 StandoutNobel
Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects
2003 Standout
A gradient of childhood self-control predicts health, wealth, and public safety
2011 Standout
Inducible operation of the erythropoietin 3' enhancer in multiple cell lines: evidence for a widespread oxygen-sensing mechanism.
1993 StandoutNobel
Hypoxia induces lymphocyte adhesion to human mesenchymal cells via an LFA-1-dependent mechanism
1993
Barbiturates: Their in vivo effects and potential biochemical mechanisms
1982
Prevention of Exacerbations of Chronic Obstructive Pulmonary Disease with Tiotropium, a Once-Daily Inhaled Anticholinergic Bronchodilator
2005
Synergistic effect of HIF-1α gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia
2009 StandoutNobel
Mediators produced by the endothelial cell.
1988 Nobel
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
Tiotropium for stable chronic obstructive pulmonary disease
2005
Dose response study of ipratropium bromide aerosol on maximum exercise performance in stable patients with chronic obstructive pulmonary disease.
1996
PAF-mediated pulmonary edema: a new role for acid sphingomyelinase and ceramide
2004
Connective tissue growth factor mediates transforming growth factor β‐induced collagen synthesis: down‐regulation by cAMP
1999
Works of Mitchell Friedman being referenced
Acute effects of an aerosol hair spray on tracheal mucociliary transport.
1977
Pharmacoeconomic Evaluation of COPD
2000
The cascade mechanism to explain ozone toxicity: The role of lipid ozonation products
1995
Formoterol Therapy for Chronic Obstructive Pulmonary Disease: A Review of the Literature
2002
Economic Burden of Chronic Obstructive Pulmonary Disease
2001
Extended Therapy With Ipratropium Is Associated With Improved Lung Function in Patients With COPD
1996
Expression of TNF and the Necessity of TNF Receptors in Bleomycin-Induced Lung Injury in Mice
1998
The Effect of Growth Hormone on Weight Gain and Pulmonary Function in Patients with Chronic Obstructive Lung Disease
1991
Pharmacoeconomic Evaluation of a Combination of Ipratropium Plus Albuterol Compared With Ipratropium Alone and Albuterol Alone in COPD
1999
Dose Response to Ipratropium as a Nebulized Solution in Patients with Chronic Obstructive Pulmonary Disease: A Three-Center Study
1989
A new mechanism for the toxicity of ozone
1995
Differential Effects of Tumor Necrosis Factor-α and Platelet-Activating Factor on Bovine Pulmonary Artery Endothelial Cells in Vitro
1994
Ozone inhibits endothelial cell cyclooxygenase activity through formation of hydrogen peroxide
1987
Upregulation of the PDGF-alpha Receptor Precedes Asbestos-induced Lung Fibrosis in Rats
1998
Interleukin-2 Directly Increases Albumin Permeability of Bovine and Human Vascular Endothelium In Vitro
1992
Upregulation of the p75 But Not the p55 TNF- α Receptor mRNA after Silica and Bleomycin Exposure and Protection from Lung Injury in Double Receptor Knockout Mice
1999
Use of a Long-acting Inhaled β 2 -Adrenergic Agonist, Salmeterol Xinafoate, in Patients with Chronic Obstructive Pulmonary Disease
2001
Effect of Ozone on Platelet-activating Factor Production in Phorbol-differentiated HL60 Cells, a Human Bronchial Epithelial Cell Line (BEAS S6), and Primary Human Bronchial Epithelial Cells
1992
Induction of Inflammatory Mediators in Human Airway Epithelial Cells by Lipid Ozonation Products
1999
Sensory Nerves Promote Ozone-induced Lung Inflammation in Mice
2001
Deposition, Clearance, and Effects of Aerosolized Amiloride in Sheep Airways 1– 3
1986
Hyperinnervation of the Airways in Transgenic Mice Overexpressing Nerve Growth Factor
1998
Long-Acting Bronchodilation with Once-Daily Dosing of Tiotropium (Spiriva) in Stable Chronic Obstructive Pulmonary Disease
2000
Connective tissue growth factor mRNA expression is upregulated in bleomycin-induced lung fibrosis
1998
Effect of hypoxia on prostacyclin production in cultured pulmonary artery endothelium
1986
Acute and chronic effects of barbiturates on depolarization-induced calcium influx into rat synaptosomes
1980
Phospho-Akt Overexpression in Non–Small Cell Lung Cancer Confers Significant Stage-Independent Survival Disadvantage
2004
Enalapril protects mice from pulmonary hypertension by inhibiting TNF-mediated activation of NF-κB and AP-1
2002
Distribution and uptake of helium, carbon monoxide, and acetylene in the lungs during high frequency oscillation ventilation
1986
Effects of acute and chronic ethanol administration on whole mouse brain synaptosomal calcium influx
1980
Alveolar macrophage apoptosis and TNF-α, but not p53, expression correlate with murine response to bleomycin
1998
Reduced oxygen tension induces pulmonary endothelium to release a pulmonary smooth muscle cell mitogen(s).
1987