Citation Impact
Citing Papers
T cell metabolism drives immunity
2015
Phosphofructokinase 1 Glycosylation Regulates Cell Growth and Metabolism
2012 Science
Semipermeable lipid bilayers exhibit diastereoselectivity favoring ribose
2005 StandoutNobel
Unified Synthesis of Polycyclic Alkaloids by Complementary Carbonyl Activation**
2021 StandoutNobel
Direct and Catalytic C ‐Glycosylation of Arenes: Expeditious Synthesis of the Remdesivir Nucleoside**
2021 StandoutNobel
Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides
2019 StandoutNobel
Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis
2023 StandoutNobel
NOX4 functions as a mitochondrial energetic sensor coupling cancer metabolic reprogramming to drug resistance
2017
A Mitochondrial Switch Promotes Tumor Metastasis
2014
Chaetocin-induced ROS-mediated apoptosis involves ATM–YAP1 axis and JNK-dependent inhibition of glucose metabolism
2014
Mitigating risk in academic preclinical drug discovery
2015
Emerging roles of PKM2 in cell metabolism and cancer progression
2012 StandoutNobel
Altered metabolite levels in cancer: implications for tumour biology and cancer therapy
2016
Teaching the design principles of metabolism
2012
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
Acute Activation of Oxidative Pentose Phosphate Pathway as First-Line Response to Oxidative Stress in Human Skin Cells
2015
Mechanisms of SARS-CoV-2 entry into cells
2021 Standout
Targeting cancer metabolism: a therapeutic window opens
2011
Ferroptosis as a p53-mediated activity during tumour suppression
2015 StandoutNature
Rocking cell metabolism: revised functions of the key glycolytic regulator PKM2 in cancer
2012
Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate
2012 Standout
Quantitative flux analysis reveals folate-dependent NADPH production
2014 Nature
Reactive Oxygen Species: Physiological Roles in the Regulation of Vascular Cells
2014
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection
2013 Nature
Best Practices for QSAR Model Development, Validation, and Exploitation
2010
Modulation of oxidative stress as an anticancer strategy
2013 Standout
Functional Genomic Landscape of Human Breast Cancer Drivers, Vulnerabilities, and Resistance
2016
TIGAR Is Required for Efficient Intestinal Regeneration and Tumorigenesis
2013
Links between metabolism and cancer
2012
Oxidative stress and cancer: An overview
2012
Machine learning for molecular and materials science
2018 StandoutNature
Dissecting fibrosis: therapeutic insights from the small-molecule toolbox
2015
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Redox-Dependent Control of FOXO/DAF-16 by Transportin-1
2013
Functionalization, preparation and use of cell-laden gelatin methacryloyl–based hydrogels as modular tissue culture platforms
2016
The Keap1–Nrf2 system in cancers: stress response and anabolic metabolism
2012
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites
2021 StandoutNobel
Human Intestinal Transporter Database: QSAR Modeling and Virtual Profiling of Drug Uptake, Efflux and Interactions
2012
Oligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells
2016
Reductive carboxylation supports redox homeostasis during anchorage-independent growth
2016 Nature
Colloid Formation by Drugs in Simulated Intestinal Fluid
2010 Nobel
Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine
2016 StandoutNobel
Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells
2012 Nature
Graphene nanoribbons as a drug delivery agent for lucanthone mediated therapy of glioblastoma multiforme
2014
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
2015 StandoutNature
Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
2015 Standout
Specific CLK Inhibitors from a Novel Chemotype for Regulation of Alternative Splicing
2011
The Nrf2 regulatory network provides an interface between redox and intermediary metabolism
2014 Standout
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
Pyruvate kinase: Function, regulation and role in cancer
2015
How Chemoproteomics Can Enable Drug Discovery and Development
2012
Mechanisms and Functions of Inflammasomes
2014 Standout
Therapeutic suppression of premature termination codons: Mechanisms and clinical considerations (Review)
2014
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
2017 Standout
The PI3K Pathway in Human Disease
2017 Standout
Cellular mechanisms and physiological consequences of redox-dependent signalling
2014 Standout
Loss of the Oxidative Stress Sensor NPGPx Compromises GRP78 Chaperone Activity and Induces Systemic Disease
2012
Mitochondria and cancer
2012 Standout
VEGF in Signaling and Disease: Beyond Discovery and Development
2019 Standout
Targeting T cell metabolism for therapy
2015
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Beyond oxidative stress: an immunologist's guide to reactive oxygen species
2013
Role of Endothelial Cell Metabolism in Vessel Sprouting
2013
Direction of actin flow dictates integrin LFA-1 orientation during leukocyte migration
2017 StandoutNobel
Oxidative Dimerization of PHD2 is Responsible for its Inactivation and Contributes to Metabolic Reprogramming via HIF-1α Activation
2016
Metabolic Regulation of Redox Status in Stem Cells
2014
Open Source Bayesian Models. 1. Application to ADME/Tox and Drug Discovery Datasets
2015
Furo[3,2‐b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway
2018
Advances in engineering hydrogels
2017 StandoutScience
Anthracyclines suppress pheochromocytoma cell characteristics, including metastasis, through inhibition of the hypoxia signaling pathway
2017 StandoutNobel
Noncovalent Functionalization of Graphene and Graphene Oxide for Energy Materials, Biosensing, Catalytic, and Biomedical Applications
2016 Standout
Make better, safer biomaterials
2016 Nature
Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials
2015 Standout
Complete integrin headpiece opening in eight steps
2013
Furo[3,2‐b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway
2018
Pore-forming activity and structural autoinhibition of the gasdermin family
2016 StandoutNature
Energetic Coupling between an Oxidizable Cysteine and the Phosphorylatable N-Terminus of Human Liver Pyruvate Kinase
2012
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Classification of Cytochrome P450 Inhibitors and Noninhibitors Using Combined Classifiers
2011
Predictive Models for Cytochrome P450 Isozymes Based on Quantitative High Throughput Screening Data
2011
The deafness gene DFNA5 induces programmed cell death through mitochondria and MAPK-related pathways
2015
Inhibition of 19S proteasome-associated deubiquitinases by metal-containing compounds
2015
Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals
2022 StandoutScienceNobel
Cysteine-Mediated Redox Signaling: Chemistry, Biology, and Tools for Discovery
2013
WhichCyp: prediction of cytochromes P450 inhibition
2013
Rational Tuning of Fluorobenzene Probes for Cysteine‐Selective Protein Modification
2018 StandoutNobel
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
Diverse Functional Roles of Reactive Cysteines
2012
Metabolic reprogramming and cancer progression
2020 StandoutScience
The Essential Roles of Chemistry in High-Throughput Screening Triage
2014
The CDK4/6 inhibitor LY2835219 has potent activity in combination with mTOR inhibitor in head and neck squamous cell carcinoma
2016
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
A systematic dissection of determinants and consequences of snoRNA-guided pseudouridylation of human mRNA
2022 StandoutNobel
HDACs and HDAC Inhibitors in Cancer Development and Therapy
2016
Reactive Oxygen Species in Metabolic and Inflammatory Signaling
2018 Standout
PET imaging of tumor glycolysis downstream of hexokinase through noninvasive measurement of pyruvate kinase M2
2015
The Halogen Bond
2016 Standout
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Chemistry: Chemical con artists foil drug discovery
2014 StandoutNature
Generation and Detection of Reactive Oxygen Species in Photocatalysis
2017 Standout
A key role for transketolase-like 1 in tumor metabolic reprogramming
2016
Energetic Coupling between an Oxidizable Cysteine and the Phosphorylatable N-Terminus of Human Liver Pyruvate Kinase
2013
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Chemical Glycoproteomics
2016 StandoutNobel
The 13C-N.M.R. spectra of alditols
1980
Glyco-seek: Ultrasensitive Detection of Protein-Specific Glycosylation by Proximity Ligation Polymerase Chain Reaction
2016 StandoutNobel
Works of Min Shen being referenced
Molecular basis for the high-affinity binding and stabilization of firefly luciferase by PTC124
2010
Auranofin Induces Lethal Oxidative and Endoplasmic Reticulum Stress and Exerts Potent Preclinical Activity against Chronic Lymphocytic Leukemia
2014
Structure-Guided Design of a High-Affinity Platelet Integrin α IIb β 3 Receptor Antagonist That Disrupts Mg 2+ Binding to the MIDAS
2012
Heparan sulfate assists SARS-CoV-2 in cell entry and can be targeted by approved drugs in vitro
2020
Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy
2015
Synthesis and biological evaluation of analogues of the kinase inhibitor nilotinib as Abl and Kit inhibitors
2012
Comprehensive characterization of cytochrome P450 isozyme selectivity across chemical libraries
2009
Rational selection of training and test sets for the development of validated QSAR models
2003
Biochemical, Cellular, and Biophysical Characterization of a Potent Inhibitor of Mutant Isocitrate Dehydrogenase IDH1
2014
Evaluation of thieno[3,2-b]pyrrole[3,2-d]pyridazinones as activators of the tumor cell specific M2 isoform of pyruvate kinase
2010
High-Throughput Screening for the Identification of New Therapeutic Options for Metastatic Pheochromocytoma and Paraganglioma
2014
Evaluation of substituted 6-arylquinazolin-4-amines as potent and selective inhibitors of cdc2-like kinases (Clk)
2009
Lucanthone and Its Derivative Hycanthone Inhibit Apurinic Endonuclease-1 (APE1) by Direct Protein Binding
2011
2-Oxo-N-aryl-1,2,3,4-tetrahydroquinoline-6-sulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinase
2011
A Highly Potent and Selective Caspase 1 Inhibitor that Utilizes a Key 3‐Cyanopropanoic Acid Moiety
2010
Evaluation of Substituted N,N′-Diarylsulfonamides as Activators of the Tumor Cell Specific M2 Isoform of Pyruvate Kinase
2009
Dual inhibition of HDAC and EGFR signaling with CUDC-101 induces potent suppression of tumor growth and metastasis in anaplastic thyroid cancer
2015
Quantitative Structure−Activity Relationship Analysis of Functionalized Amino Acid Anticonvulsant Agents Using k Nearest Neighbor and Simulated Annealing PLS Methods
2002
Development and Validation of k-Nearest-Neighbor QSPR Models of Metabolic Stability of Drug Candidates
2003
Remdesivir: A Review of Its Discovery and Development Leading to Emergency Use Authorization for Treatment of COVID-19
2020
Identification and Optimization of Inhibitors of Trypanosomal Cysteine Proteases: Cruzain, Rhodesain, and TbCatB
2009
The crystal structures of allitol and D -iditol.
1972
Torin2 targets dysregulated pathways in anaplastic thyroid cancer and inhibits tumor growth and metastasis
2015
Application of Predictive QSAR Models to Database Mining: Identification and Experimental Validation of Novel Anticonvulsant Compounds
2004
Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses
2011 Science