Standout Papers
Citation Impact
Citing Papers
Human cerebral organoids recapitulate gene expression programs of fetal neocortex development
2015 StandoutNobel
Epigenetic memory of active gene transcription is inherited through somatic cell nuclear transfer
2005 StandoutNobel
Derepression of BDNF Transcription Involves Calcium-Dependent Phosphorylation of MeCP2
2003 StandoutScience
Reversal of Neurological Defects in a Mouse Model of Rett Syndrome
2007 StandoutScience
Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
2009 StandoutScience
A Neuroligin-3 Mutation Implicated in Autism Increases Inhibitory Synaptic Transmission in Mice
2007 StandoutScienceNobel
Transposition-Driven Genomic Heterogeneity in the Drosophila Brain
2013 StandoutScienceNobel
Epigenetic regulation of hypoxic sensing disrupts cardiorespiratory homeostasis
2012 StandoutNobel
Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons
2013 StandoutNobel
Induction of human neuronal cells by defined transcription factors
2011 StandoutNatureNobel
Syndromes of disordered chromatin remodeling
2003
An integrated map of genetic variation from 1,092 human genomes
2012 StandoutNature
Phenotypic plasticity and the epigenetics of human disease
2007 Nature
Integrative single-cell analysis of transcriptional and epigenetic states in the human adult brain
2017
Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development
2001
Methylation-Induced Repression— Belts, Braces, and Chromatin
1999
Molecular genetics of Rett syndrome and clinical spectrum of MECP2 mutations
2001
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
MeCP2 Binds to 5hmC Enriched within Active Genes and Accessible Chromatin in the Nervous System
2012
Mild overexpression of MeCP2 causes a progressive neurological disorder in mice
2004
A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells
2010
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
DNA methylation patterns and epigenetic memory
2002 Standout
The epigenetic regulation of mammalian telomeres
2007
Epigenetic regulation of aging stem cells
2011
Epigenetics in human disease and prospects for epigenetic therapy
2004 StandoutNature
Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2)
2004
Methylation-dependent silencing at the H19 imprinting control region by MeCP2
2002
A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome
2001
Selective Transcription in Response to an Inflammatory Stimulus
2010
Wild-type microglia arrest pathology in a mouse model of Rett syndrome
2012 Nature
SWI/SNF Regulates the Cellular Response to Hypoxia
2008
Shifting Players and Paradigms in Cell-Specific Transcription
2009
Review: Chromatin Structural Features and Targets That Regulate Transcription
2000
Constructing and Deconstructing Stem Cell Models of Neurological Disease
2011
Mouse behavioral tasks relevant to autism: Phenotypes of 10 inbred strains
2006
Unwinding chromatin for development and growth: a few genes at a time
2007
Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1
2007 StandoutNatureNobel
Methyl-CpG-binding protein 2 mutations in Rett syndrome
2000
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
SWI/SNF nucleosome remodellers and cancer
2011 Standout
The Story of Rett Syndrome: From Clinic to Neurobiology
2007
The Caenorhabditis elegans SOMI-1 zinc finger protein and SWI/SNF promote regulation of development by the mir-84 microRNA
2011 StandoutNobel
Functional consequences of Rett syndrome mutations on human MeCP2
2000
Disruption of an Evolutionarily Novel Synaptic Expression Pattern in Autism
2016 StandoutNobel
NuRD and SIN3
2000
MeCP2 dysfunction in Rett syndrome and related disorders
2006
Methylation matters
2001
Enrichment and Site Mapping of O-Linked N-Acetylglucosamine by a Combination of Chemical/Enzymatic Tagging, Photochemical Cleavage, and Electron Transfer Dissociation Mass Spectrometry
2009
The SWI/SNF complex and cancer
2009
Clan Genomics and the Complex Architecture of Human Disease
2011
esBAF facilitates pluripotency by conditioning the genome for LIF/STAT3 signalling and by regulating polycomb function
2011
MECP2 truncating mutations cause histone H4 hyperacetylation in Rett syndrome
2001
MECP2 is progressively expressed in post-migratory neurons and is involved in neuronal maturation rather than cell fate decisions
2004
Searching for ways out of the autism maze: genetic, epigenetic and environmental clues
2006
Selective and antagonistic functions of SWI/SNF and Mi-2β nucleosome remodeling complexes during an inflammatory response
2006
Genomic Imprinting Disrupted by a Maternal Effect Mutation in the Dnmt1 Gene
2001
MicroRNA-mediated switching of chromatin-remodelling complexes in neural development
2009 Nature
Cause and Consequences of Genetic and Epigenetic Alterations in Human Cancer
2008
BRD7, a Novel PBAF-specific SWI/SNF Subunit, Is Required for Target Gene Activation and Repression in Embryonic Stem Cells
2008
DNA methylation and Rett syndrome
2003
Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy
2013 Standout
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
2003 Standout
Selective Ablation of Retinoblastoma Protein Function by the RET Finger Protein
2005
chromVAR: inferring transcription-factor-associated accessibility from single-cell epigenomic data
2017
X-chromosome inactivation: counting, choice and initiation
2001
Suppression of inflammation by a synthetic histone mimic
2010 StandoutNatureNobel
Regulation of Dendritic Development by Neuron-Specific Chromatin Remodeling Complexes
2007
L1 retrotransposition in neurons is modulated by MeCP2
2010 Nature
Transcriptional control of the inflammatory response
2009
The expression of methyl CpG binding factor MeCP2 correlates with cellular differentiation in the developing rat brain and in cultured cells
2003
SS18 Together with Animal-Specific Factors Defines Human BAF-Type SWI/SNF Complexes
2012
Neuroligins and neurexins link synaptic function to cognitive disease
2008 StandoutNatureNobel
DNA Recognition by the Methyl-CpG Binding Domain of MeCP2
2001
Systemic Delivery of MeCP2 Rescues Behavioral and Cellular Deficits in Female Mouse Models of Rett Syndrome
2013
Hippocampal synaptic plasticity is impaired in the Mecp2-null mouse model of Rett syndrome
2005
Genomic Rearrangements and Gene Copy-Number Alterations as a Cause of Nervous System Disorders
2006
Expression Pattern of the Rett Syndrome Gene MeCP2 in Primate Prefrontal Cortex
2001
Above and Within the Genome: Epigenetics Past and Present
2001
Gene expression patterns vary in clonal cell cultures from Rett syndrome females with eight different MECP2 mutations
2002
Cerebral organoids model human brain development and microcephaly
2013 StandoutNature
Learning and Memory and Synaptic Plasticity Are Impaired in a Mouse Model of Rett Syndrome
2006
The Hallmarks of Aging
2013 Standout
Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice
2001
The nuclear actin-related proteins Arp7 and Arp9: a dimeric module that cooperates with architectural proteins for chromatin remodeling
2003
Mice with Truncated MeCP2 Recapitulate Many Rett Syndrome Features and Display Hyperacetylation of Histone H3
2002
Reversible Disruption of mSWI/SNF (BAF) Complexes by the SS18-SSX Oncogenic Fusion in Synovial Sarcoma
2013
Are Complex Behaviors Specified by Dedicated Regulatory Genes? Reasoning from Drosophila
2001 StandoutNobel
MicroRNA-mediated conversion of human fibroblasts to neurons
2011 Nature
Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumours
2001
Identification of a polymorphic, neuron-specific chromatin remodeling complex
2002
The Human Condition—A Molecular Approach
2014 StandoutNobel
Autism Spectrum Disorders
2000
Quantitative localization of heterogeneous methyl-CpG-binding protein 2 (MeCP2) expression phenotypes in normal and Rett syndrome brain by laser scanning cytometry
2001
Differential Requirements for Runx Proteins in CD4 Repression and Epigenetic Silencing during T Lymphocyte Development
2002
Identification and Characterization of the DNA Binding Domain of CpG-binding Protein
2001
Organoid single-cell genomic atlas uncovers human-specific features of brain development
2019 StandoutNatureNobel
DNA Hypomethylation Perturbs the Function and Survival of CNS Neurons in Postnatal Animals
2001
Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21
2015 StandoutNobel
Metabolic cross-talk allows labeling of O-linked β- N -acetylglucosamine-modified proteins via the N -acetylgalactosamine salvage pathway
2011 StandoutNobel
Hijacking the Chromatin Remodeling Machinery: Impact ofSWI/SNFPerturbations in Cancer
2009
Neuronal maturation defect in induced pluripotent stem cells from patients with Rett syndrome
2011
Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics
2015
Inactivation of the PBRM1 tumor suppressor gene amplifies the HIF-response in VHL −/− clear cell renal carcinoma
2017 StandoutNobel
MyoD Targets Chromatin Remodeling Complexes to the Myogenin Locus Prior to Forming a Stable DNA-Bound Complex
2005
EUKARYOTIC CYTOSINE METHYLTRANSFERASES
2005 Standout
Modeling hepatitis C virus infection using human induced pluripotent stem cells
2012 StandoutNobel
DNA Methylation-Related Chromatin Remodeling in Activity-Dependent Bdnf Gene Regulation
2003 Science
MeCP2 binds to 5hmc enriched within active genes and accessible chromatin in the nervous system
2013
A General Mechanism for Network-Dosage Compensation in Gene Circuits
2010 StandoutScienceNobel
Postnatal Neurodevelopmental Disorders: Meeting at the Synapse?
2003 Science
GENETIC EFFECTS OF METHYLATION DIETS
2002
Dual role of Brg chromatin remodeling factor in Sonic hedgehog signaling during neural development
2011
An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency
2009
Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function
2011 StandoutNobel
The Biology of Chromatin Remodeling Complexes
2009 Standout
Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes (II)
2018 Standout
Corepressor-Dependent Silencing of Chromosomal Regions Encoding Neuronal Genes
2002 Science
Reduced cortical activity due to a shift in the balance between excitation and inhibition in a mouse model of Rett Syndrome
2005
Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling
2007 StandoutNobel
The Role of DNA Methylation in Mammalian Epigenetics
2001 StandoutScience
Complementary roles of gasotransmitters CO and H2S in sleep apnea
2017 StandoutNobel
Translating the Histone Code
2001 StandoutScience
Expression of MeCP2 in postmitotic neurons rescues Rett syndrome in mice
2004
Rett Syndrome: A Prototypical Neurodevelopmental Disorder
2004
Candidate autism gene screen identifies critical role for cell-adhesion molecule CASPR2 in dendritic arborization and spine development
2012 StandoutNobel
Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation
2013 StandoutNobel
Transcriptional profiling of a mouse model for Rett syndrome reveals subtle transcriptional changes in the brain
2002
Unusually rapid evolution of Neuroligin-4 in mice
2008 StandoutNobel
MOLECULAR GENETICS OF T CELL DEVELOPMENT
2004
A DNA insulator prevents repression of a targeted X-linked transgene but not its random or imprinted X inactivation
2006 StandoutNobel
DNA Methylation and Histone Deacetylation in the Control of Gene Expression: Basic Biochemistry to Human Development and Disease
2001
Metabolic labeling enables selective photocrosslinking of O-GlcNAc-modified proteins to their binding partners
2012 StandoutNobel
Chemical Glycoproteomics
2016 StandoutNobel
Mouse neurexin-1α deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments
2009 StandoutNobel
Works of Mimi Wan being referenced
Manganese Phosphate Self-assembled Nanoparticle Surface and Its application for Superoxide Anion Detection
2016
Spectrum of MECP2 mutations in Rett syndrome
2001
Genome-wide detection of DNase I hypersensitive sites in single cells and FFPE tissue samples
2015 Nature
Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
1999 Standout
An Essential Switch in Subunit Composition of a Chromatin Remodeling Complex during Neural Development
2007
Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes
2002 Nature
Rett Syndrome and Beyond: Recurrent Spontaneous and Familial MECP2 Mutations at CpG Hotspots
1999
Sequential Roles of Brg, the ATPase Subunit of BAF Chromatin Remodeling Complexes, in Thymocyte Development
2003
Induction of TLR4-target genes entails calcium/calmodulin-dependent regulation of chromatin remodeling
2009