Standout Papers
Citation Impact
Citing Papers
ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation
2009 StandoutScience
Identification of a Primary Target of Thalidomide Teratogenicity
2010 StandoutScience
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
2009 StandoutScience
Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney
2006 StandoutNobel
A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM
2005
Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism
2009 StandoutNobel
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
The DNA-damage response in human biology and disease
2009 StandoutNature
Nucleosome Movement by CHRAC and ISWI without Disruption or trans-Displacement of the Histone Octamer
1999
Histone acetylation and chromatin signature in stem cell identity and cancer
2007
Dynamic personalities of proteins
2007 StandoutNature
Structural determinants of peptide-binding orientation and of sequence specificity in SH3 domains
1994 Nature
Genome-wide Mapping of HATs and HDACs Reveals Distinct Functions in Active and Inactive Genes
2009
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Chromatin Modifications and Their Function
2007 Standout
GCN5 acetyltransferase complex controls glucose metabolism through transcriptional repression of PGC-1α
2006
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
2011 StandoutNature
The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia
2017 StandoutNobel
Twenty-Five Years of the Nucleosome, Fundamental Particle of the Eukaryote Chromosome
1999 StandoutNobel
Eomesodermin, a Key Early Gene in Xenopus Mesoderm Differentiation
1996 StandoutNobel
The molecular regulation of myogenesis
2000
Mismatch repair and nucleotide excision repair proteins cooperate in the recognition of DNA interstrand crosslinks
2009 StandoutNobel
Exchange of N-CoR Corepressor and Tip60 Coactivator Complexes Links Gene Expression by NF-κB and β-Amyloid Precursor Protein
2002
Histone acetyltransferase complexes: one size doesn't fit all
2007
The FATC Domains of PIKK Proteins Are Functionally Equivalent and Participate in the Tip60-dependent Activation of DNA-PKcs and ATM
2006
CpG motifs in bacterial DNA trigger direct B-cell activation
1995 StandoutNature
High-Resolution Profiling of Histone Methylations in the Human Genome
2007 Standout
Interactions of Human Mismatch Repair Proteins MutSα and MutLα with Proteins of the ATR-Chk1 Pathway
2009 StandoutNobel
Regulation of nucleotide excision repair activity by transcriptional and post-transcriptional control of the XPA protein
2010 StandoutNobel
The Ubiquitin Ligase Activity in the DDB2 and CSA Complexes Is Differentially Regulated by the COP9 Signalosome in Response to DNA Damage
2003
Mapping and analysis of chromatin state dynamics in nine human cell types
2011 StandoutNature
A Myc Network Accounts for Similarities between Embryonic Stem and Cancer Cell Transcription Programs
2010
The Histone Chaperone Spt6 Is Required for Activation-induced Cytidine Deaminase Target Determination through H3K4me3 Regulation
2012 StandoutNobel
SIRT1 Regulates UV-Induced DNA Repair through Deacetylating XPA
2010
Checkpoint control and cancer
2011
Dissection of Amyloid-β Precursor Protein-dependent Transcriptional Transactivation
2004 StandoutNobel
Antisense Oligonucleotides as Therapeutic Agents—Is the Bullet Really Magical?
1993 Science
Therapeutic modulation of endogenous gene function by agents with designed DNA-sequence specificities
2003
Protein modules and signalling networks
1995 StandoutNature
Histone H3.1 and H3.3 Complexes Mediate Nucleosome Assembly Pathways Dependent or Independent of DNA Synthesis
2004
Genome-wide prediction of conserved and nonconserved enhancers by histone acetylation patterns
2006
Computational redesign of endonuclease DNA binding and cleavage specificity
2006 StandoutNatureNobel
DNA double-strand breaks: signaling, repair and the cancer connection
2001 Standout
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
25 years after the nucleosome model: chromatin modifications
2000
The MyoD family of transcription factors and skeletal myogenesis
1995
Characterization of the Interactome of the Human MutL Homologues MLH1, PMS1, and PMS2
2006
Triple helix-directed psoralen crosslinks are recognized by Uvr(A)BC excinuclease
1998
Phosphorylation of H2AX at Short Telomeres in T Cells and Fibroblasts
2004 StandoutNobel
Branch Migration and Holliday Junction Resolution Catalyzed by Activities from Mammalian Cells
2001
Nucleosome mobilization catalysed by the yeast SWI/SNF complex
1999 Nature
Estrogen Receptor-α Directs Ordered, Cyclical, and Combinatorial Recruitment of Cofactors on a Natural Target Promoter
2003
Structure and function of the AAA+ nucleotide binding pocket
2011
AAA+ superfamily ATPases: common structure–diverse function
2001
Multiple Functions of Jab1 Are Required for Early Embryonic Development and Growth Potential in Mice
2004 StandoutNobel
DNA Damage and Its Links to Neurodegeneration
2014
RNA helicases at work: binding and rearranging
2010
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
2010 StandoutNobel
Accumulation of the FACT complex, as well as histone H3.3, serves as a target marker for somatic hypermutation
2013 StandoutNobel
Mutagenesis in Mammalian Cells Induced by Triple Helix Formation and Transcription-Coupled Repair
1996 Science
Peptide nucleic acid-targeted mutagenesis of a chromosomal gene in mouse cells
1998
Single-molecule biophysics: at the interface of biology, physics and chemistry
2007
Reuniting the contrasting functions of H2A.ZThis paper is one of a selection of papers published in this Special Issue, entitled 27th International West Coast Chromatin and Chromosome Conference, and has undergone the Journal's usual peer review process.
2006
Histone Acetyltransferases
2001 Standout
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Angiotensin II–Induced Growth Responses in Isolated Adult Rat Hearts
1995
Structure and Mechanism of Helicases and Nucleic Acid Translocases
2007
Binding of F-spondin to amyloid-β precursor protein: A candidate amyloid-β precursor protein ligand that modulates amyloid-β precursor protein cleavage
2004 StandoutNobel
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
Targeted Mutagenesis in Mammalian Cells Mediated by Intracellular Triple Helix Formation
1995
Recombination Induced by Triple-Helix-Targeted DNA Damage in Mammalian Cells
1996
Investigating DNA supercoiling in eukaryotic genomes
2017
ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage
2007 StandoutScience
Chromatin remodeling by DNA bending, not twisting
2005 StandoutNobel
Ribosome Biogenesis in the YeastSaccharomyces cerevisiae
2013
Cancer Genome Landscapes
2013 StandoutScience
Translating the Histone Code
2001 StandoutScience
Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling
2020 StandoutNobel
Chromatin remodeling by nucleosome disassembly in vitro
2006 StandoutNobel
When repair meets chromatin
2002
Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit
2016 StandoutNobel
Recruitment of the Type B Histone Acetyltransferase Hat1p to Chromatin Is Linked to DNA Double-Strand Breaks
2006
Human DNA Repair Genes
2001 StandoutScienceNobel
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation
2012 StandoutNobel
Unique double-ring structure of the peroxisomal Pex1/Pex6 ATPase complex revealed by cryo-electron microscopy
2015 StandoutNobel
Simulating the electrostatic guidance of the vectorial translocations in hexameric helicases and translocases
2009 StandoutNobel
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
2004 StandoutNobel
Structural analysis of the RSC chromatin-remodeling complex
2002 StandoutNobel
Cleavage of Amyloid-β Precursor Protein and Amyloid-β Precursor-like Protein by BACE 1
2004 StandoutNobel
Works of Mikhaïl Grigoriev being referenced
Migration of a Holliday Junction through a Nucleosome Directed by the E. coli RuvAB Motor Protein
1998
Involvement of the TIP60 Histone Acetylase Complex in DNA Repair and Apoptosis
2000 Standout
A cruciform structural transition provides a molecular switch for chromosome structure and dynamics 1 1Edited by I. Tinoco
2000
The ATPase and helicase activities of Prp43p are stimulated by the G‐patch protein Pfa1p during yeast ribosome biogenesis
2009
Peptide nucleic acids directed to the promoter of the α-chain of the interleukin-2 receptor
1996
KOPS: DNA motifs that control E. coli chromosome segregation by orienting the FtsK translocase
2005
Repression of c-fos promoter by MyoD on muscle cell differentiation
1993 Nature
Physical interaction between the histone acetyl transferase Tip60 and the DNA double-strand breaks sensor MRN complex
2010
A Histone Octamer Blocks Branch Migration of a Holliday Junction
1997
A triple helix-forming oligonucleotide-intercalator conjugate acts as a transcriptional repressor via inhibition of NF kappa B binding to interleukin-2 receptor alpha-regulatory sequence.
1992
Inhibition of gene expression by triple helix-directed DNA cross-linking at specific sites.
1993
Single-molecule study of RuvAB-mediated Holliday-junction migration
2004