Standout Papers
- The β Sliding Clamp Binds to Multiple Sites within MutL and MutS (2006)
- Molecular Biology: Principles and Practice (2011)
- Human Cd4+ T Lymphocytes Consistently Respond to the Latent Epstein-Barr Virus Nuclear Antigen Ebna1 (2000)
- Involvement of the β Clamp in Methyl-directed Mismatch Repair in Vitro (2009)
- Saccharomyces cerevisiae MutLα Is a Mismatch Repair Endonuclease (2007)
Citation Impact
Citing Papers
Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro
2003 StandoutNobel
MutL traps MutS at a DNA mismatch
2015 StandoutNobel
A possible mechanism for exonuclease 1-independent eukaryotic mismatch repair
2009 StandoutNobel
hMSH3 and hMSH6 interact with PCNA and colocalize with it to replication foci
2001
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
2014 StandoutNatureNobel
Mispair-specific Recruitment of the Mlh1-Pms1 Complex Identifies Repair Substrates of the Saccharomyces cerevisiae Msh2-Msh3 Complex
2014
Mechanisms in Eukaryotic Mismatch Repair
2006 StandoutNobel
The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA
1994 Nature
Differential Requirement for Proliferating Cell Nuclear Antigen in 5′ and 3′ Nick-directed Excision in Human Mismatch Repair
2004
Transfer of the MSH2·MSH6 Complex from Proliferating Cell Nuclear Antigen to Mispaired Bases in DNA
2002
DNA Polymerase III Holoenzyme from Thermus thermophilus Identification, Expression, Purification of Components, and Use to Reconstitute a Processive Replicase
2002
Overproduction in Escherichia coli and Characterization of Yeast Replication Factor C Lacking the Ligase Homology Domain
2000
Requirement of DNA Polymerase Activity of Yeast Rad30 Protein for Its Biological Function
1999
Clamp and clamp loader structures of the human checkpoint protein complexes, Rad9‐1‐1 and Rad17‐RFC
2002
Expression and Physicochemical Characterization of Human Proliferating Cell Nuclear Antigen
1995
Relating Structure to Function in 29 DNA Polymerase
1996
Chromosome fragility at GAA tracts in yeast depends on repeat orientation and requires mismatch repair
2008
Interaction of Checkpoint Proteins Hus1/Rad1/Rad9 with DNA Base Excision Repair Enzyme MutY Homolog in Fission Yeast, Schizosaccharomyces pombe
2004
Visualization of Eukaryotic DNA Mismatch Repair Reveals Distinct Recognition and Repair Intermediates
2011
Mechanism Whereby Proliferating Cell Nuclear Antigen Stimulates Flap Endonuclease 1
2000
Crystal Structure of a pol α Family Replication DNA Polymerase from Bacteriophage RB69
1997 StandoutNobel
Single molecule studies of DNA mismatch repair
2014
Inference of Macromolecular Assemblies from Crystalline State
2007 Standout
PCNA binding proteins
1999
Error-Prone DNA Polymerases
2001
Visualizing polynucleotide polymerase machines at work
2006 StandoutNobel
Did DNA replication evolve twice independently?
1999
Cip1 inhibits DNA replication but not PCNA-dependent nucleotide excision—repair
1994
Instability and decay of the primary structure of DNA
1993 StandoutNatureNobel
Crystal Structure of a DinB Lesion Bypass DNA Polymerase Catalytic Fragment Reveals a Classic Polymerase Catalytic Domain
2001 StandoutNobel
Analysis of the Interaction between the Saccharomyces cerevisiae MSH2-MSH6 and MLH1-PMS1 Complexes with DNA Using a Reversible DNA End-blocking System
2005
Regulatory Roles of p21 and Apurinic/Apyrimidinic Endonuclease 1 in Base Excision Repair
2001
Target preference of Type III-A CRISPR-Cas complexes at the transcription bubble
2019 StandoutNobel
Cdk inhibitors: on the threshold of checkpoints and development
1994
Single-molecule imaging reveals mechanisms of protein disruption by a DNA translocase
2010 Nature
Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution.
1995
Assembly of Functional Replication Factor C Expressed Using Recombinant Baculoviruses
1997
A Flexible Interface between DNA Ligase and PCNA Supports Conformational Switching and Efficient Ligation of DNA
2006
The COOH-terminal Domain of the RNA Polymerase α Subunit in Transcriptional Enhancement and Deactivation at the Bacteriophage T4 Late Promoter
1995
Molecular mechanisms of DNA mismatch repair
2001
Interactions of Human Mismatch Repair Proteins MutSα and MutLα with Proteins of the ATR-Chk1 Pathway
2009 StandoutNobel
The MutSα-Proliferating Cell Nuclear Antigen Interaction in Human DNA Mismatch Repair
2008 StandoutNobel
Feedback controls and G2 checkpoints: Fission yeast as a model system
1993
Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA
1995 Nature
Building a Replisome from Interacting Pieces
1999 StandoutNobel
Dendritic Cells Expand Epstein Barr Virus Specific CD8+ T Cell Responses More Efficiently Than EBV Transformed B Cells
2005 StandoutNobel
Assembly and Molecular Activities of the MutS Tetramer
2003 StandoutNobel
The endonuclease domain of MutL interacts with the β sliding clamp
2010
CD4 and CD8 T cell responses to tumour-associated Epstein–Barr virus antigens in nasopharyngeal carcinoma patients
2007
Crystal Structure of a Y-Family DNA Polymerase in Action
2001
Functionally interacting telomerase RNAs in the yeast telomerase complex
1997 StandoutNobel
Biochemical Characterization of DNA Damage Checkpoint Complexes: Clamp Loader and Clamp Complexes with Specificity for 5′ Recessed DNA
2003
DNA mismatch repair and mutation avoidance pathways
2002
Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 Å resolution
1998 Nature
Endonucleolytic Function of MutLα in Human Mismatch Repair
2006 StandoutNobel
Proliferating cell nuclear antigen: More than a clamp for DNA polymerases
1997
Repair of abasic sites in DNA
2003
Flexibility of Eukaryotic Okazaki Fragment Maturation through Regulated Strand Displacement Synthesis
2008
Evidence for Preferential Mismatch Repair of Lagging Strand DNA Replication Errors in Yeast
2003
Requirement for PCNA in DNA Mismatch Repair at a Step Preceding DNA Resynthesis
1996
MutS switches between two fundamentally distinct clamps during mismatch repair
2011
The Structure of T. aquaticus DNA Polymerase III Is Distinct from Eukaryotic Replicative DNA Polymerases
2006 StandoutNobel
Novel DNA Polymerases Offer Clues to the Molecular Basis of Mutagenesis
1999
Functions of human DNA polymerases η, κ and ι suggested by their properties, including fidelity with undamaged DNA templates
2003
Lagging Strand DNA Synthesis at the Eukaryotic Replication Fork Involves Binding and Stimulation of FEN-1 by Proliferating Cell Nuclear Antigen
1995
Structural and functional insights provided by crystal structures of DNA polymerases and their substrate complexes
1998 StandoutNobel
Functional Interactions among the Subunits of Replication Factor C Potentiate and Modulate Its ATPase Activity
1998
Physical Interactions among Human Checkpoint Control Proteins HUS1p, RAD1p, and RAD9p, and Implications for the Regulation of Cell Cycle Progression
2000
Common structural features of nucleic acid polymerases
2002
Functional Interaction of Proliferating Cell Nuclear Antigen with MSH2-MSH6 and MSH2-MSH3 Complexes
2000
Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1
1995 Nature
DNA Ligase III Is Recruited to DNA Strand Breaks by a Zinc Finger Motif Homologous to That of Poly(ADP-ribose) Polymerase
1999
A small peptide inhibitor of DNA replication defines the site of interaction between the cyclin-dependent kinase inhibitor p21WAF1 and proliferating cell nuclear antigen
1995
EBNA1-specific CD4+ T cells in healthy carriers of Epstein-Barr virus are primarily Th1 in function
2001 StandoutNobel
hMSH2–hMSH6 Forms a Hydrolysis-Independent Sliding Clamp on Mismatched DNA
1999
The Coordinated Functions of the E. coli MutS and MutL Proteins in Mismatch Repair
2003
In vitro anti-tumor immune response induced by dendritic cells transfected with EBV-LMP2 recombinant adenovirus
2006
Structure and Function of the UvrB Protein
1995 StandoutNobel
Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA
1994
Insights into Strand Displacement and Processivity from the Crystal Structure of the Protein-Primed DNA Polymerase of Bacteriophage φ29
2004 StandoutNobel
Identification of the Acidic Residues in the Active Site of DNA Polymerase III
1999
The mechanism of mismatch repair and the functional analysis of mismatch repair defects in Lynch syndrome
2013
Nucleotide-promoted Release of hMutSα from Heteroduplex DNA Is Consistent with an ATP-dependent Translocation Mechanism
1998 StandoutNobel
Reconstitution of Recombinant Human Replication Factor C (RFC) and Identification of an RFC Subcomplex Possessing DNA-dependent ATPase Activity
1998
Suppression of inflammation by a synthetic histone mimic
2010 StandoutNatureNobel
Crystal structure of an archaebacterial DNA polymerase
1999
G1 phase progression: Cycling on cue
1994 Standout
Overproduction and Affinity Purification of Saccharomyces cerevisiae Replication Factor C
1997
The replication factory targeting sequence/PCNA-binding site is required in G1 to control the phosphorylation status of DNA ligase I
1999
Atomic Structure of the Clamp Loader Small Subunit from Pyrococcus furiosus
2001
Reconstitution and Molecular Analysis of the hRad9-hHus1-hRad1 (9-1-1) DNA Damage Responsive Checkpoint Complex
2001
MSH-MLH complexes formed at a DNA mismatch are disrupted by the PCNA sliding clamp
2001
AP Endonuclease 1 Coordinates Flap Endonuclease 1 and DNA Ligase I Activity in Long Patch Base Excision Repair
2002
ATP-dependent interaction of human mismatch repair proteins and dual role of PCNA in mismatch repair
1998
Multiple competition reactions for RPA order the assembly of the DNA polymerase delta holoenzyme
1999
MutLα and Proliferating Cell Nuclear Antigen Share Binding Sites on MutSβ
2010 StandoutNobel
The N Terminus of Saccharomyces cerevisiae Msh6 Is an Unstructured Tether to PCNA
2007
Mechanism of Stimulation of Human DNA Ligase I by the Rad9-Rad1-Hus1 Checkpoint Complex
2006 StandoutNobel
Phosphoesterase domains associated with DNA polymerases of diverse origins
1998
Retention of the Human Rad9 Checkpoint Complex in Extraction-resistant Nuclear Complexes after DNA Damage
2000
A tale of two tails: Activation of DNA damage checkpoint kinase Mec1/ATR by the 9-1-1 clamp and by Dpb11/TopBP1
2009
A 39 Amino Acid Fragment of the Cell Cycle Regulator p21 Is Sufficient to Bind PCNA and Partially Inhibit DNA Replication in vivo
1996
Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin
2002
Contrasting Roles of Dendritic Cells and B Cells in the Immune Control of Epstein-Barr Virus
2003
Checkpoint-Dependent Activation of Mutagenic Repair in Saccharomyces cerevisiae pol3-01 Mutants
2000
Dendritic cells efficiently cross-prime HLA class I-restricted cytolytic T lymphocytes when pulsed with both apoptotic and necrotic cells but not with soluble cell-derived lysates
2000
The quenching of electrochemiluminescence upon oligonucleotide hybridization
2004
Structures of the Human Rad17-Replication Factor C and Checkpoint Rad 9-1-1 Complexes Visualized by Glycerol Spray/Low Voltage Microscopy
2002 StandoutNobel
Separation of mutation avoidance and antirecombination functions in an Escherichia coli mutS mutant
2005
Three-Dimensional Electron Microscopy of the Clamp Loader Small Subunit from Pyrococcus furiosus
2001
Chemistry of Class 1 CRISPR-Cas effectors: Binding, editing, and regulation
2020 StandoutNobel
Inhibitors of mammalian G1 cyclin-dependent kinases.
1995 Standout
Dendritic Cells in Transplantation—Friend or Foe?
2001
DNA ligases in the repair and replication of DNA
2000
Structure-based predictions of Rad1, Rad9, Hus1 and Rad17 participation in sliding clamp and clamp-loading complexes
2000
Mechanisms of trinucleotide repeat instability during human development
2010
A plethora of lesion-replicating DNA polymerases
1999
The dinB Gene Encodes a Novel E. coli DNA Polymerase, DNA Pol IV, Involved in Mutagenesis
1999
Human DNA ligase I completely encircles and partially unwinds nicked DNA
2004 Nature
DNA Ligase I and Proliferating Cell Nuclear Antigen Form a Functional Complex
2001
Novel Human and Mouse Homologs of Saccharomyces cerevisiae DNA Polymerase η
1999
A Defined Human System That Supports Bidirectional Mismatch-Provoked Excision
2004 StandoutNobel
Mechanisms and functions of DNA mismatch repair
2007
Nucleases: diversity of structure, function and mechanism
2010
DNA mismatch repair: Molecular mechanism, cancer, and ageing
2008
Inhibition of Nucleotide Excision Repair by the Cyclin-dependent Kinase Inhibitor p21
1995 StandoutNobel
Escherichia coli DNA Polymerase III Holoenzyme Subunits α, β, and γ Directly Contact the Primer-Template
1995
Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
1995 Standout
Polymerases and the Replisome: Machines within Machines
1998
The clamp-loading complex for processive DNA replication
2004
Post-replicative base excision repair in replication foci
1999
Analysis of Interactions Between Mismatch Repair Initiation Factors and the Replication Processivity Factor PCNA
2005
The Orc4p and Orc5p Subunits of the Xenopus and Human Origin Recognition Complex Are Related to Orc1p and Cdc6p
1998 StandoutNobel
Modular Organization of T4 DNA Polymerase
1995
Electrochemiluminescent hybridization chip with electric field aided mismatch discrimination
2006
DNA-Thumb Interactions and Processivity of T7 DNA Polymerase in Comparison to Yeast Polymerase η
2004
ATP-dependent structural change of the eukaryotic clamp-loader protein, replication factor C
2000
PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair
2010 StandoutNobel
Crystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonarius
1999 Nobel
Saccharomyces cerevisiaeCTF18 and CTF4 Are Required for Sister Chromatid Cohesion
2001
Checkpoints: Controls That Ensure the Order of Cell Cycle Events
1989 StandoutScienceNobel
A specific subdomain in φ29 DNA polymerase confers both processivity and strand-displacement capacity
2005 StandoutNobel
Purification and characterization of human DNA damage checkpoint Rad complexes
2001 StandoutNobel
The CD8+ Dendritic Cell Subset Selectively Endocytoses Dying Cells in Culture and In Vivo
2002 StandoutNobel
Properties of initiation complexes formed between Escherichia coli DNA polymerase III holoenzyme and primed DNA in the absence of ATP.
1987
The mechanism of action of T7 DNA polymerase
1998
Assembly of a functional replication complex without ATP hydrolysis: a direct interaction of bacteriophage T4 gp45 with T4 DNA polymerase.
1993
Characterization of a Highly Conserved Binding Site of Mlh1 Required for Exonuclease I-Dependent Mismatch Repair
2008
DNA MISMATCH REPAIR
2005
Isolation and Characterization of New Proliferating Cell Nuclear Antigen (POL30) Mutator Mutants That Are Defective in DNA Mismatch Repair
2002
CD4+T-Cell Effectors Inhibit Epstein-Barr Virus-Induced B-Cell Proliferation
2001
Loss of EBNA1-specific memory CD4+ and CD8+ T cells in HIV-infected patients progressing to AIDS-related non-Hodgkin lymphoma
2005
Replication factors required for SV40 DNA replication in vitro. I. DNA structure-specific recognition of a primer-template junction by eukaryotic DNA polymerases and their accessory proteins
1991
Quality Control by DNA Repair
1999 StandoutScienceNobel
Single-molecule imaging reveals target-search mechanisms during DNA mismatch repair
2012
Dendritic Cells Initiate Immune Control of Epstein-Barr Virus Transformation of B Lymphocytes In Vitro
2003 StandoutNobel
Evidence for the Presentation of Major Histocompatibility Complex Class I–restricted Epstein-Barr Virus Nuclear Antigen 1 Peptides to CD8+ T Lymphocytes
2004
Replication protein A-mediated recruitment and activation of Rad17 complexes
2003
Defective bypass replication of a leading strand cyclobutane thymine dimer in xeroderma pigmentosum variant cell extracts.
1998
The in vitro replication of DNA containing the SV40 origin.
1990
Classical Electrostatics in Biology and Chemistry
1995 StandoutScience
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Localization of the active site of the alpha subunit of the Escherichia coli DNA polymerase III holoenzyme
1997
The Organization of Replication and Transcription
1999 Science
cDNAs encoding the large subunit of human replication factor C.
1993
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
Fission yeast rad17: a homologue of budding yeast RAD24 that shares regions of sequence similarity with DNA polymerase accessory proteins.
1995
Human and mouse homologs of Escherichia coli DinB (DNA polymerase IV), members of the UmuC/DinB superfamily
1999
Dendritic Cells Cross-Present Latency Gene Products from Epstein-Barr Virus–Transformed B Cells and Expand Tumor-Reactive Cd8+ Killer T Cells
2001 StandoutNobel
In vivo requirement for RecJ, ExoVII, ExoI, and ExoX in methyl-directed mismatch repair
2001 StandoutNobel
DNA Mismatch Repair: Molecular Mechanisms and Biological Function
2003
Escherichia coli DNA polymerase III holoenzyme footprints three helical turns of its primer
1994
Mutagenicity in Escherichia coli of the major DNA adduct derived from the endogenous mutagen malondialdehyde
1997
Molecular Matchmakers
1993 StandoutScienceNobel
A Bipartite Polymerase–Processivity Factor Interaction: Only the Internal β Binding Site of the α Subunit is Required for Processive Replication by the DNA Polymerase III Holoenzyme
2005
Electrochemiluminescence (ECL)
2004 Standout
PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance
2010 StandoutNobel
Mechanism of elongation of primed DNA by DNA polymerase delta, proliferating cell nuclear antigen, and activator 1.
1990
Use of a macromolecular crowding agent to dissect interactions and define functions in transcriptional activation by a DNA-tracking protein: bacteriophage T4 gene 45 protein and late transcription.
1994
A conserved domain of the large subunit of replication factor C binds PCNA and acts like a dominant negative inhibitor of DNA replication in mammalian cells.
1996
THE DNA REPLICATION FORK IN EUKARYOTIC CELLS
1998
Atomic Structure of the DNA Repair [4Fe-4S] Enzyme Endonuclease III
1992 Science
Mismatch repair in Xenopus egg extracts: DNA strand breaks act as signals rather than excision points.
1996
The Importance of Exogenous Antigen in Priming the Human CD8+ T Cell Response: Lessons from the EBV Nuclear Antigen EBNA1
2000
Divergence of a DNA Replication Gene Cluster in the T4-Related Bacteriophage RB69
1998
Distinct memory CD4+ T-cell subsets mediate immune recognition of Epstein Barr virus nuclear antigen 1 in healthy virus carriers
2006
Artificial Molecular Machines
2015 Standout
Growth factor modulation of p53-mediated growth arrest versus apoptosis.
1995
Dual Stimulation of Epstein-Barr Virus (EBV)-Specific CD4+- and CD8+-T-Cell Responses by a Chimeric Antigen Construct: Potential Therapeutic Vaccine for EBV-Positive Nasopharyngeal Carcinoma
2003
ATP-independent loading of the proliferating cell nuclear antigen requires DNA ends.
1993
Stimulation of the processivity of the DNA polymerase of bacteriophage T4 by the polymerase accessory proteins. The role of ATP hydrolysis
1991
ECL—Electrochemical luminescence
2007
Cytolytic CD4+-T-Cell Clones Reactive to EBNA1 Inhibit Epstein-Barr Virus-Induced B-Cell Proliferation
2003
Inhibition of cyclin-dependent kinases by p21.
1995
The Multiple Biological Roles of the 3′→5′ Exonuclease ofSaccharomyces cerevisiaeDNA Polymerase δ Require Switching between the Polymerase and Exonuclease Domains
2004
Mismatch Recognition-Coupled Stabilization of Msh2-Msh6 in an ATP-Bound State at the Initiation of DNA Repair
2003
Electrogenerated Chemiluminescence and Its Biorelated Applications
2008 Standout
Saccharomyces cerevisiae pol30 (Proliferating Cell Nuclear Antigen) Mutations Impair Replication Fidelity and Mismatch Repair
1999
Rapid assembly of the bacteriophage T4 core replication complex on a linear primer/template construct.
1993
Differential Immunogenicity of Epstein-Barr Virus Latent-Cycle Proteins for Human CD4+T-Helper 1 Responses
2001
p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene.
1995
Targeting the nuclear antigen 1 of Epstein-Barr virus to the human endocytic receptor DEC-205 stimulates protective T-cell responses
2008 StandoutNobel
Cyclin-Dependent Kinase Inhibitor p21 Modulates the DNA Primer-Template Recognition Complex
1998
A Transcriptional Enhancer Whose Function Imposes a Requirement That Proteins Track Along DNA
1992 Science
Identification of Transcription Complexes that Contain the Double Bromodomain Protein Brd2 and Chromatin Remodeling Machines
2006
Structural Basis for the Transition from Initiation to Elongation Transcription in T7 RNA Polymerase
2002 StandoutScienceNobel
p21Cip1/Waf1 disrupts the recruitment of human Fen1 by proliferating-cell nuclear antigen into the DNA replication complex.
1996
Extrahelical (CAG)/(CTG) triplet repeat elements support proliferating cell nuclear antigen loading and MutLα endonuclease activation
2013 StandoutNobel
Tolerogenic Dendritic Cells
2003 StandoutNobel
Slow Conformational Changes in MutS and DNA Direct Ordered Transitions between Mismatch Search, Recognition and Signaling of DNA Repair
2013
DNA Replication in Eukaryotic Cells
2002 Standout
Functions of replication factor C and proliferating-cell nuclear antigen: functional similarity of DNA polymerase accessory proteins from human cells and bacteriophage T4.
1990
Functional Reversion of Antigen-Specific CD8+ T Cells from Patients with Hodgkin Lymphoma following In Vitro Stimulation with Recombinant Polyepitope
2006
Asymmetric ATP Binding and Hydrolysis Activity of the Thermus aquaticus MutS Dimer Is Key to Modulation of Its Interactions with Mismatched DNA
2004
The carboxyl terminus of the bacteriophage T4 DNA polymerase is required for holoenzyme complex formation
1996
A read-ahead function in archaeal DNA polymerases detects promutagenic template-strand uracil
1999
Structural and biochemical studies of human proliferating cell nuclear antigen complexes provide a rationale for cyclin association and inhibitor design
2005
Residues at the Carboxy Terminus of T4 DNA Polymerase Are Important Determinants for Interaction with the Polymerase Accessory Proteins
1997
DNA replication.
1988
The human checkpoint sensor and alternative DNA clamp Rad9–Rad1–Hus1 modulates the activity of DNA ligase I, a component of the long-patch base excision repair machinery
2005
Fluorescence energy transfer between the primer and the beta subunit of the DNA polymerase III holoenzyme.
1992
Recognition and Repair of Compound DNA Lesions (Base Damage and Mismatch) by Human Mismatch Repair and Excision Repair Systems
1997 StandoutNobel
Clamp Subunit Dissociation Dictates Bacteriophage T4 DNA Polymerase Holoenzyme Disassembly
1998
Epstein-Barr Nuclear Antigen 1-Specific CD4+ Th1 Cells Kill Burkitt’s Lymphoma Cells
2002
Structure-Function Analysis of Fission Yeast Hus1-Rad1-Rad9 Checkpoint Complex
2001
Mammalian DNA Polymerase Auxiliary Proteins: Analysis of Replication Factor C-Catalyzed Proliferating Cell Nuclear Antigen Loading onto Circular Double-Stranded DNA
1995
Cellular Responses to Viral Infection in Humans: Lessons from Epstein-Barr Virus
2007
Works of Mike O’Donnell being referenced
A peptide switch regulates DNA polymerase processivity
2003
Saccharomyces cerevisiae MutLα Is a Mismatch Repair Endonuclease
2007 StandoutNobel
DNA Polymerase δ Is Highly Processive with Proliferating Cell Nuclear Antigen and Undergoes Collision Release upon Completing DNA
2008
[32] Radiolabeling of proteins for biochemical studies
1995
Fidelity of Escherichia coli DNA Polymerase III Holoenzyme
1997
Three-dimensional structure of the β subunit of E. coli DNA polymerase III holoenzyme: A sliding DNA clamp
1992
Structure of the C-Terminal Region of p21WAF1/CIP1 Complexed with Human PCNA
1996
DNA POLYMERASE III HOLOENZYME: Structure and Function of a Chromosomal Replicating Machine
1995
[33] Cycling of Escherichia coli DNA polymerase III from one sliding clamp to another: Model for lagging strand
1995
Replisome Assembly at oriC, the Replication Origin of E. coli, Reveals an Explanation for Initiation Sites outside an Origin
1999
The β Sliding Clamp Binds to Multiple Sites within MutL and MutS
2006 StandoutNobel
A Complex Consisting of Human Replication Factor C p40, p37, and p36 Subunits Is a DNA-dependent ATPase and an Intermediate in the Assembly of the Holoenzyme
1997
An explanation for lagging strand replication: Polymerase hopping among DNA sliding clamps
1994
ATP Binding to the Escherichia coli Clamp Loader Powers Opening of the Ring-shaped Clamp of DNA Polymerase III Holoenzyme
1998
Cross-utilization of the β Sliding Clamp by Replicative Polymerases of Evolutionary Divergent Organisms
2000
Assembly of a Chromosomal Replication Machine: Two DNA Polymerases, a Clamp Loader, and Sliding Clamps in One Holoenzyme Particle.
1995
Assembly of a Chromosomal Replication Machine: Two DNA Polymerases, a Clamp Loader, and Sliding Clamps in One Holoenzyme Particle.
1995
The ring-type polymerase sliding clamp family.
2001
Clamp loader structure predicts the architecture of DNA polymerase III holoenzyme and RFC
2001
Thermus thermophilis dnaX Homolog Encoding γ- and τ-like Proteins of the Chromosomal Replicase
1997
Overproduction and analysis of eukaryotic multiprotein complexes in Escherichia coli using a dual-vector strategy
2003
Mechanisms of DNA replication
2000
Clamp loaders and sliding clamps
2002
The replisome uses mRNA as a primer after colliding with RNA polymerase
2008 Nature
Structure of a Sliding Clamp on DNA
2008
Roles of E. coli DNA polymerases IV and V in lesion-targeted and untargeted SOS mutagenesis
2000 Nature
Deletion Analysis of the Large Subunit p140 in Human Replication Factor C Reveals Regions Required for Complex Formation and Replication Activities
1997
Ordered ATP Hydrolysis in the γ Complex Clamp Loader AAA+ Machine
2003
Trading Places on DNA—A Three-Point Switch Underlies Primer Handoff from Primase to the Replicative DNA Polymerase
1999
Sliding Clamps of DNA Polymerases
1993
Replisome Assembly Reveals the Basis for Asymmetric Function in Leading and Lagging Strand Replication
1996
Mechanism of the E. coli τ Processivity Switch during Lagging-Strand Synthesis
2003
Accessory protein function in the DNA polymerase III holoenzyme from E. coli
1992
Crystal Structure of the Processivity Clamp Loader Gamma (γ) Complex of E. coli DNA Polymerase III
2001
The DNA Replication Machine of a Gram-positive Organism
2000
Assembly of a Chromosomal Replication Machine: Two DNA Polymerases, a Clamp Loader, and Sliding Clamps in One Holoenzyme Particle. I. ORGANIZATION OF THE CLAMP LOADER
1995
A Molecular Switch in a Replication Machine Defined by an Internal Competition for Protein Rings
1996
cDNA Cloning and Gene Mapping of Human Homologs forSchizosaccharomyces pombe rad17, rad1,andhus1and Cloning of Homologs from Mouse,Caenorhabditis elegans,andDrosophila melanogaster
1998
Processivity of DNA polymerases: two mechanisms, one goal
1998
Dynamics of β and Proliferating Cell Nuclear Antigen Sliding Clamps in Traversing DNA Secondary Structure
2000
Isolation of Human and Fission Yeast Homologues of the Budding Yeast Origin Recognition Complex Subunit ORC5: Human Homologue (ORC5L) Maps to 7q22
1997
Development of a Novel Helicase Assay Using Electrochemiluminescence
2001
Assembly of a Chromosomal Replication Machine: Two DNA Polymerases, a Clamp Loader, and Sliding Clamps in One Holoenzyme Particle.
1995
Molecular Mechanism and Energetics of Clamp Assembly inEscherichia coli
2000
Escherichia coli expression vectors containing a protein kinase recognition motif, His6-tag and hemagglutinin epitope
1995
Toroidal proteins: Running rings around DNA
1998
Identification of Regions within the Four Small Subunits of Human Replication Factor C Required for Complex Formation and DNA Replication
1997
Principles and Concepts of DNA Replication in Bacteria, Archaea, and Eukarya
2013
Sliding clamps: A (tail)ored fit
2000
DNA replication: enzymology and mechanisms
1994
Human RPA (hSSB) interacts with EBNA1, the latent origin binding protein of Epstein-Barr virus
1998
Structural analysis of a eukaryotic sliding DNA clamp–clamp loader complex
2004 Nature
The Influence of the Proliferating Cell Nuclear Antigen-interacting Domain of p21 on DNA Synthesis Catalyzed by the Human and Saccharomyces cerevisiae Polymerase δ Holoenzymes
1997
Structural and functional similarities of prokaryotic and eukaryotic DNA polymerase sliding clamps
1995
DNA Structure Requirements for the Escherichia coliγ Complex Clamp Loader and DNA Polymerase III Holoenzyme
2000
Clamp loading, unloading and intrinsic stability of the PCNA, β and gp45 sliding clamps of human, E. coli and T4 replicases
1996
Motion of a DNA Sliding Clamp Observed by Single Molecule Fluorescence Spectroscopy
2008
Crystal structure of the DNA polymerase processivity factor of T4 bacteriophage 1 1Edited by I. A. Wilson
2000
Involvement of the β Clamp in Methyl-directed Mismatch Repair in Vitro
2009 StandoutNobel
Dynamics of DNA polymerase III holoenzyme of Escherichia coli in replication of a multiprimed template.
1985
Fidelity of Escherichia coli DNA Polymerase IV
2002
The sliding clamp of DNA polymerase III holoenzyme encircles DNA.
1992
Accessory proteins bind a primed template and mediate rapid cycling of DNA polymerase III holoenzyme from Escherichia coli.
1987
DNA polymerase III accessory proteins. III. holC and holD encoding chi and psi
1993
Crystal Structure of the δ′ Subunit of the Clamp-Loader Complex of E. coli DNA Polymerase III
1997
DNA polymerase III accessory proteins. II. Characterization of delta and delta'
1993
CELLULAR DNA REPLICASES: Components and Dynamics at the Replication Fork
2005
Overproduction, purification, and characterization of EBNA1, the origin binding protein of Epstein-Barr virus.
1991
Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase
2010 Science
Total reconstitution of DNA polymerase III holoenzyme reveals dual accessory protein clamps.
1990
Homology in accessory proteins of replicative polymerases—E.colito humans
1993
Processive replication is contingent on the exonuclease subunit of DNA polymerase III holoenzyme.
1990
Dynamics of DNA-tracking by two sliding-clamp proteins.
1996
Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme.
1994
UmuD′ 2 C is an error-prone DNA polymerase, Escherichia coli pol V
1999
ATP hydrolysis catalyzed by human replication factor C requires participation of multiple subunits
1998
holE, the gene coding for the theta subunit of DNA polymerase III of Escherichia coli: characterization of a holE mutant and comparison with a dnaQ (epsilon-subunit) mutant
1994
Studies on the interactions between human replication factor C and human proliferating cell nuclear antigen
1999
DNA polymerase III accessory proteins. V. Theta encoded by holE
1993
In vitro reconstitution of human replication factor C from its five subunits.
1996
Analysis of the ATPase subassembly which initiates processive DNA synthesis by DNA polymerase III holoenzyme.
1991
Complete replication of templates by Escherichia coli DNA polymerase III holoenzyme.
1985
Interaction of the β sliding clamp with MutS, ligase, and DNA polymerase I
2001
DNA polymerase δ isolated from Schizosaccharomyces pombe contains five subunits
1997
Mechanism of Processivity Clamp Opening by the Delta Subunit Wrench of the Clamp Loader Complex of E. coli DNA Polymerase III
2001
Biochemical basis of SOS-induced mutagenesis in Escherichia coli : Reconstitution of in vitro lesion bypass dependent on the UmuD′ 2 C mutagenic complex and RecA protein
1998
Human Cd4+ T Lymphocytes Consistently Respond to the Latent Epstein-Barr Virus Nuclear Antigen Ebna1
2000 StandoutNobel
An interaction between DNA ligase I and proliferating cell nuclear antigen: Implications for Okazaki fragment synthesis and joining
1997
Assembly of a Chromosomal Replication Machine: Two DNA Polymerases, a Clamp Loader, and Sliding Clamps in One Holoenzyme Particle.
1995
Reconstitution of human replication factor C from its five subunits in baculovirus-infected insect cells
1996
Proteomic and genomic characterization of chromatin complexes at a boundary
2005
Reconstitution of repair-gap UV mutagenesis with purified proteins from Escherichia coli: a role for DNA polymerases III and II.
1996
Constitution of the twin polymerase of DNA polymerase III holoenzyme.
1991
Specificity and enzymatic mechanism of the editing exonuclease of Escherichia coli DNA polymerase III.
1991
Activity of the purified mutagenesis proteins UmuC, UmuD', and RecA in replicative bypass of an abasic DNA lesion by DNA polymerase III.
1992
Mechanism of the sliding beta-clamp of DNA polymerase III holoenzyme
1991
DNA polymerase III accessory proteins. IV. Characterization of chi and psi
1993