Citation Impact
Citing Papers
TRP channel activation by reversible covalent modification
2006 StandoutNobel
Modulation of immune cell reactivity with cis -binding Siglec agonists
2021 StandoutNobel
Normal gut microbiota modulates brain development and behavior
2011 Standout
Localized cell stimulation by nitric oxide using a photoactive porous coordination polymer platform
2013 StandoutNobel
Naloxone Protects Rat Dopaminergic Neurons against Inflammatory Damage through Inhibition of Microglia Activation and Superoxide Generation
2000
Inflammation and Alzheimer's disease
2000 Standout
Ischemia and reperfusion—from mechanism to translation
2011 Standout
Apoptosis in the nervous system
2000 StandoutNature
Microglia: active sensor and versatile effector cells in the normal and pathologic brain
2007 Standout
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
2007 StandoutNatureNobel
Nitric oxide activates TRP channels by cysteine S-nitrosylation
2006
Toll-like receptors as targets in chronic liver diseases
2009
Thapsigargin induces microglial transformation from amoeboid to ramified type in vitro
1999
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
2006 Standout
Glutamate uptake
2001 Standout
Drotrecogin Alfa (Activated) in Adults with Septic Shock
2012 Standout
β-Amyloid-Stimulated Microglia Induce Neuron Death via Synergistic Stimulation of Tumor Necrosis Factor α and NMDA Receptors
2005
Nitric oxide inhibits capacitative Ca2+ entry and enhances endoplasmic reticulum Ca2+ uptake in bovine vascular endothelial cells
2002
Toll-Like Receptor 4 Promotes Tubular Inflammation in Diabetic Nephropathy
2011
Transient receptor potential channels: targeting pain at the source
2008 StandoutNobel
ATP mediates rapid microglial response to local brain injury in vivo
2005 Standout
From chills to chilis: mechanisms for thermosensation and chemesthesis via thermoTRPs
2007 StandoutNobel
Microglia and inflammation-mediated neurodegeneration: Multiple triggers with a common mechanism
2005
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
A comparative review of cell culture systems for the study of microglial biology in Alzheimer’s disease
2012
Dose-dependent activation of microglial cells by Toll-like receptor agonists alone and in combination
2005
Store-Operated Calcium Channels
2005 Standout
β-Amyloid-specific upregulation of stearoyl coenzyme A desaturase-1 in macrophages
2003
Glutamate neurotoxicity and diseases of the nervous system
1988 Standout
Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9
2016 Standout
Brain injury in premature infants: a complex amalgam of destructive and developmental disturbances
2008 Standout
Regulation of β-Adrenergic Receptor Signaling by S-Nitrosylation of G-Protein-Coupled Receptor Kinase 2
2007 StandoutNobel
Neurodegenerative disorders: the role of peroxynitrite
1999
Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord
2009 Standout
Interaction of Alzheimer β-amyloid peptide with the human monocytic cell line THP-1 results in a protein kinase C-dependent secretion of tumor necrosis factor-α
1997
Transforming Growth Factor-β1 Inhibition of Macrophage Activation Is Mediated via Smad3
2000
Transient changes in the presence of nitric oxide synthases and nitrotyrosine immunoreactivity after focal cortical lesions
1997
Complement Component C1q Modulates the Phagocytosis of Aβ by Microglia
2000
Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity
2012 Standout
A randomized, double-blind, placebo-controlled trial of TAK-242 for the treatment of severe sepsis*
2010
TAK-242 selectively suppresses Toll-like receptor 4-signaling mediated by the intracellular domain
2008
Alzheimer's Disease
2010 Standout
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
Coinduction of Nitric Oxide Synthase, Argininosuccinate Synthetase, and Argininosuccinate Lyase in Lipopolysaccharide-treated Rats
1996
Stress-induced immune dysfunction: implications for health
2005 Standout
Relevance of protein nitration in brain injury: a key pathophysiological mechanism in neurodegenerative, autoimmune, or inflammatory CNS diseases and stroke
2003
β‐Amyloid inhibits integrated mitochondrial respiration
and key enzyme activities
2001
Reactive Astrocytes: Production, Function, and Therapeutic Potential
2017 Standout
Alcoholic Liver Disease: Pathogenesis and New Therapeutic Targets
2011 Standout
Nitric Oxide Synthase in Reactive Astrocytes Adjacent to β-Amyloid Plaques
1997
BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain
2005 StandoutNature
The role of nitric oxide after a short period of liver ischemia-reperfusion
2003
Microglia enhance β‐amyloid peptide‐induced toxicity in cortical and mesencephalic neurons by producing reactive oxygen species
2002
Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid β-peptide and the membrane lipid peroxidation product 4-hydroxynonenal
2008
?-Amyloid protein enhances macrophage production of oxygen free radicals and glutamate
1997
The NALP3 inflammasome is involved in the innate immune response to amyloid-β
2008 Standout
Peroxynitrite: biochemistry, pathophysiology and development of therapeutics
2007 Standout
TAK-242 (Resatorvid), a Small-Molecule Inhibitor of Toll-Like Receptor (TLR) 4 Signaling, Binds Selectively to TLR4 and Interferes with Interactions between TLR4 and Its Adaptor Molecules
2010
Suppression of Aβ-induced monocyte neurotoxicity by antiinflammatory compounds
1997
Inflammation in obesity, diabetes, and related disorders
2022 Standout
TRPV1 and TRPA1 Mediate Peripheral Nitric Oxide-Induced Nociception in Mice
2009 StandoutNobel
Thapsigargin induces microglial transformation from amoeboid- to ramified- type in vivo
2000
Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses
2009 Standout
Toll-like Receptor 4 Modulation as a Strategy to Treat Sepsis
2010
Neuronal injury mediated via stimulation of microglial toll‐like receptor‐9 (TLR9)
2003
Regional Difference in Susceptibility to Lipopolysaccharide-Induced Neurotoxicity in the Rat Brain: Role of Microglia
2000
Inflammatory mechanisms in Alzheimer's disease: inhibition of beta-amyloid-stimulated proinflammatory responses and neurotoxicity by PPARgamma agonists.
2000
Corticotropin-Releasing Factor Receptor 1 in Mouse Spleen: Expression After Immune Stimulation and Identification of Receptor-Bearing Cells
1999
Apoptosis, Neurotrophic Factors and Neurodegeneration
1997
Nitric oxide and the immune response
2001 Standout
A Toll-Like Receptor 2-Responsive Lipid Effector Pathway Protects Mammals against Skin Infections with Gram-Positive Bacteria
2005 StandoutNobel
Distinct Role for Microglia in Rotenone-Induced Degeneration of Dopaminergic Neurons
2002 Standout
Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2
2005 Standout
β-Amyloid Stimulation of Microglia and Monocytes Results in TNFα-Dependent Expression of Inducible Nitric Oxide Synthase and Neuronal Apoptosis
2001
Live tissue intrinsic emission microscopy using multiphoton-excited native fluorescence and second harmonic generation
2003 Standout
Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection
2011 StandoutNobel
Comparison of inducible nitric oxide synthase expression in the brains of Listeria monocytogenes-infected cattle, sheep, and goats and in macrophages stimulated in vitro
1997
Astrocytic nitric oxide triggers tau hyperphosphorylation in hippocampal neurons.
2005
ListeriaPathogenesis and Molecular Virulence Determinants
2001 Standout
Neuropathic Pain: From Mechanisms to Treatment
2020 Standout
MICROGLIA AS MEDIATORS OF INFLAMMATORY AND DEGENERATIVE DISEASES
1999
Toll-Like Receptor 4 Inhibitor TAK-242 Attenuates Acute Kidney Injury in Endotoxemic Sheep
2011
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
TRANSFORMING GROWTH FACTOR-β REGULATION OF IMMUNE RESPONSES
2005 Standout
Inflammatory Mechanisms in Alzheimer's Disease: Inhibition of β-Amyloid-Stimulated Proinflammatory Responses and Neurotoxicity by PPARγ Agonists
2000
Dorsal root ganglion neurons become hyperexcitable and increase expression of voltage-gated T-type calcium channels (Cav3.2) in paclitaxel-induced peripheral neuropathy
2016
Peroxynitrite mediates neurotoxicity of amyloid beta-peptide1-42- and lipopolysaccharide-activated microglia.
2002
Caspase-2 Mediates Neuronal Cell Death Induced by β-Amyloid
2000
Arginine metabolism: nitric oxide and beyond
1998 Standout
Electrochemical Analysis of Protein Nitrotyrosine and Dityrosine in the Alzheimer Brain Indicates Region-Specific Accumulation
1998
Identification of Microglial Signal Transduction Pathways Mediating a Neurotoxic Response to Amyloidogenic Fragments of β-Amyloid and Prion Proteins
1999
Physiology of Microglia
2011 Standout
Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models.
2000 Standout
Oxidative stress in neurodegeneration: cause or consequence?
2004 Standout
Works of Mie Sunamoto being referenced
Autocrine Action and Its Underlying Mechanism of Nitric Oxide on Intracellular Ca2+ Homeostasis in Vascular Endothelial Cells
2000
Therapeutic effects of TAK-242, a novel selective Toll-like receptor 4 signal transduction inhibitor, in mouse endotoxin shock model
2007
β-Amyloid protein-dependent nitric oxide production from microglial cells and neurotoxicity
1996
Discovery of Novel and Potent Small-Molecule Inhibitors of NO and Cytokine Production as Antisepsis Agents: Synthesis and Biological Activity of Alkyl 6-(N-Substituted sulfamoyl)cyclohex-1-ene-1-carboxylate
2005
Immunohistochemical expression of inducible nitric oxide synthase (iNOS) in reversible endotoxic shock studied by a novel monoclonal antibody against rat iNOS
1995