Citation Impact
Citing Papers
Role of LBPA and Alix in Multivesicular Liposome Formation and Endosome Organization
2004 StandoutScienceNobel
Lipid Rafts As a Membrane-Organizing Principle
2009 StandoutScience
A Gene Network Regulating Lysosomal Biogenesis and Function
2009 StandoutScience
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
Species-Specific Recognition of Single-Stranded RNA via Toll-like Receptor 7 and 8
2004 StandoutScience
Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA
2004 StandoutScience
Innate and Adaptive Immunity Cooperate Flexibly to Maintain Host-Microbiota Mutualism
2009 StandoutScienceNobel
Toll Pathway-Dependent Blockade of CD4 + CD25 + T Cell-Mediated Suppression by Dendritic Cells
2003 StandoutScience
Trained immunity: A program of innate immune memory in health and disease
2016 StandoutScience
Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: Activation of Toll-like receptor 7
2003
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway
2003 StandoutScience
Monocytes Heterozygous for the Asp299Gly and Thr399Ile Mutations in the Toll-like Receptor 4 Gene Show No Deficit in Lipopolysaccharide Signalling
2003
Separate Functional Domains of Human MD-2 Mediate Toll-Like Receptor 4-Binding and Lipopolysaccharide Responsiveness
2003
Intracellular sterol dynamics
2009
Circulating mitochondrial DAMPs cause inflammatory responses to injury
2010 StandoutNature
Toll receptors and pathogen resistance
2003
The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses
2004
Hydrophobicity: an ancient damage-associated molecular pattern that initiates innate immune responses
2004
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
2010 Standout
Saturation variant interpretation using CRISPR prime editing
2022
Pathogenesis and therapy of psoriasis
2007 StandoutNature
Cytokines in Atherosclerosis: Pathogenic and Regulatory Pathways
2006
The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
2001 StandoutNature
Recognition of microorganisms and activation of the immune response
2007 StandoutNature
Saturated Fatty Acid Activates but Polyunsaturated Fatty Acid Inhibits Toll-like Receptor 2 Dimerized with Toll-like Receptor 6 or 1
2004 Standout
Inactivation of Conserved C. elegans Genes Engages Pathogen- and Xenobiotic-Associated Defenses
2012 StandoutNobel
Toll-like receptors and cancer
2008
Pattern Recognition Receptors and Inflammation
2010 Standout
The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages
2005
Toll-like receptors in systemic autoimmune disease
2006
Vertebrate Smoothened functions at the primary cilium
2005 StandoutNature
Roles for accessory molecules in microbial recognition by Toll-like receptors
2006
Reciprocal Modulation of Toll-like Receptor-4 Signaling Pathways Involving MyD88 and Phosphatidylinositol 3-Kinase/AKT by Saturated and Polyunsaturated Fatty Acids
2003
NF-κB Protects Macrophages from Lipopolysaccharide-induced Cell Death
2005
Negative Regulation of Toll-like Receptor-mediated Signaling by Tollip
2002
The molecular basis of the host response to lipopolysaccharide
2009
Toll-like receptor signalling
2004 Standout
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
2005 StandoutNature
Immunity, Inflammation, and Cancer
2010 Standout
Therapeutic targeting of Toll-like receptors for inflammatory and infectious diseases
2003
Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron
2004 StandoutNature
C. elegans patched-3 is an essential gene implicated in osmoregulation and requiring an intact permease transporter domain
2011
TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88–independent TLR4 pathway
2009
Intrauterine Infection and Preterm Delivery
2000 Standout
The biology of Toll-like receptors
2000
The extracellular matrix protein mindin is a pattern-recognition molecule for microbial pathogens
2003
Innate and adaptive immunity and the pathophysiology of psoriasis
2006
Cholesterol Crystals Activate the NLRP3 Inflammasome in Human Macrophages: A Novel Link between Cholesterol Metabolism and Inflammation
2010
Origin and physiological roles of inflammation
2008 StandoutNature
TOLL-LIKE RECEPTORS IN ISCHEMIA-REPERFUSION INJURY
2009
Toll-like receptors and innate antiviral responses
2003
Toll-like receptors: critical proteins linking innate and acquired immunity
2001 Standout
Progress and challenges in translating the biology of atherosclerosis
2011 StandoutNature
Toll‐like receptors, endogenous ligands, and systemic autoimmune disease
2005
Chromatin–IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors
2002 StandoutNature
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
2010 StandoutNature
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Endogenous ligands of Toll-like receptors: implications for regulating inflammatory and immune responses
2002
Pathogen Recognition and Innate Immunity
2006 Standout
The immunopathogenesis of sepsis
2002 StandoutNature
Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein
2001 StandoutNatureNobel
Toll-Like Receptors
2003 Standout
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses
2011 StandoutNobel
The Interleukin-1 Receptor/Toll-Like Receptor Superfamily: Signal Transduction During Inflammation and Host Defense
2003
Toll Receptors: a Central Element in Innate Immune Responses
2002
Receptor-Mediated Monitoring of Tissue Well-Being Via Detection of Soluble Heparan Sulfate by Toll-Like Receptor 4
2002
Structure and Function of Toll Receptors and Their Ligands
2007
Toll-like receptor 4 polymorphisms are associated with resistance to Legionnaires' disease
2005 StandoutNobel
NCU-G1 is a highly glycosylated integral membrane protein of the lysosome
2009
Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection
2011 StandoutNobel
Identification of Small Heat Shock Protein B8 (HSP22) as a Novel TLR4 Ligand and Potential Involvement in the Pathogenesis of Rheumatoid Arthritis
2006
The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex
2009 StandoutNature
Foxp3+natural regulatory T cells preferentially form aggregates on dendritic cellsin vitroand actively inhibit their maturation
2008 StandoutNobel
Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger
2008 StandoutNobel
Injury Primes the Innate Immune System for Enhanced Toll-Like Receptor Reactivity
2003
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
The Danger Model: A Renewed Sense of Self
2002 StandoutScience
Sonic Hedgehog Induces the Segregation of Patched and Smoothened in Endosomes
2002
Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis
2006 StandoutNobel
Inhibition of Toll-like Receptor and Cytokine Signaling—A Unifying Theme in Ischemic Tolerance
2004 StandoutNobel
Regulation of Adaptive Immunity by the Innate Immune System
2010 StandoutScience
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection
2004 StandoutNobel
Interleukin 1 Receptor Dependence of Serum Transferred Arthritis Can be Circumvented by Toll-like Receptor 4 Signaling
2003
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Tissue Expression of Human Toll-Like Receptors and Differential Regulation of Toll-Like Receptor mRNAs in Leukocytes in Response to Microbes, Their Products, and Cytokines
2002
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Cholesterol Sensing, Trafficking, and Esterification
2006
Works of Michiko Watari being referenced
Determinants of NPC1 Expression and Action: Key Promoter Regions, Posttranscriptional Control, and the Importance of a “Cysteine-Rich” Loop
2000
Mutations in the Leucine Zipper Motif and Sterol-sensing Domain Inactivate the Niemann-Pick C1 Glycoprotein
1999
Lipopolysaccharide induces expression of genes encoding pro-inflammatory cytokines and the elastin-degrading enzyme, cathepsin S, in human cervical smooth-muscle cells
2000
The Extra Domain A of Fibronectin Activates Toll-like Receptor 4
2001