Citation Impact
Citing Papers
De novo protein synthesis is required for the activation-induced cytidine deaminase function in class-switch recombination
2003 StandoutNobel
T cell metabolism drives immunity
2015
Activating Mutations of NOTCH1 in Human T Cell Acute Lymphoblastic Leukemia
2004 StandoutScience
Regulation of B Versus T Lymphoid Lineage Fate Decision by the Proto-Oncogene LRF
2007 Science
β-Catenin Is Dispensable for Hematopoiesis and Lymphopoiesis
2004
ZBTB1 is a determinant of lymphoid development
2011 StandoutNobel
A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells
2012 StandoutScience
Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL
2010 StandoutNobel
Notch-induced E2A ubiquitination and degradation are controlled by MAP kinase activities
2003
Untangling the ErbB signalling network
2001 Standout
E proteins and Notch signaling cooperate to promote T cell lineage specification and commitment
2006
The ErbB2 and ErbB3 receptors and their ligand, neuregulin-1, are essential for development of the sympathetic nervous system
1998
Peripheral nervous system defects in erbB2 mutants following genetic rescue of heart development
1999
Polycomb Group Gene mel-18 Regulates Early T Progenitor Expansion by Maintaining the Expression of Hes-1, a Target of the Notch Pathway
2005
Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A
2009
Functional Interaction between SEL-10, an F-box Protein, and the Nuclear Form of Activated Notch1 Receptor
2001 StandoutNobel
Ikaros Directly Represses the Notch Target Gene Hes1 in a Leukemia T Cell Line
2008
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
Combined Loss of Hey1 and HeyL Causes Congenital Heart Defects Because of Impaired Epithelial to Mesenchymal Transition
2007
Overexpression of HES-1 is not sufficient to impose T-cell differentiation on human hematopoietic stem cells
2005
Pericytes are required for blood–brain barrier integrity during embryogenesis
2010 StandoutNature
Notch1 Signaling Promotes the Maturation of CD4 and CD8 SP Thymocytes
2000
The duration of antigen receptor signalling determines CD4+ versus CD8+ T-cell lineage fate
2000 Nature
Stem cells, cancer, and cancer stem cells
2001 StandoutNature
Identification of a T Lineage-Committed Progenitor in Adult Blood
2007
Serrate1-induced Notch signalling regulates the decision between immunity and tolerance made by peripheral CD4+ T cells
2000
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Cysteine-Rich Domain Isoforms of the Neuregulin-1 Gene Are Required for Maintenance of Peripheral Synapses
2000
Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice
2000
Wound repair and regeneration
2008 StandoutNature
Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors
2014 StandoutNature
Requirement for Notch1 signals at sequential early stages of intrathymic T cell development
2005
Osteoblastic cells regulate the haematopoietic stem cell niche
2003 StandoutNature
Regulation of αβ/γδ T Cell Lineage Commitment and Peripheral T Cell Responses by Notch/RBP-J Signaling
2004 StandoutNobel
Thicker Than Blood
2003
Neuregulin, a factor with many functions in the life of a Schwann cell
2000
Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling
2000
Notch1 Regulates Maturation of CD4+ and CD8+ Thymocytes by Modulating TCR Signal Strength
2001
Inactivation of Notch1 Impairs VDJβ Rearrangement and Allows pre-TCR-Independent Survival of Early αβ Lineage Thymocytes
2002
Regulation of B cell development by Notch/RBP-J signaling
2003 StandoutNobel
T lineage progenitors: the earliest steps en route to T lymphocytes
2006
The transcription factor Sox10 is a key regulator of peripheral glial development
2001 Standout
Laminin-1 and epidermal growth factor family members co-stimulate fetal pancreas cell proliferation and colony formation
2005
Notch signaling in T cell development
2000
The bone marrow niche for haematopoietic stem cells
2014 StandoutNature
The monolayer formation of Bergmann glial cells is regulated by Notch/RBP-J signaling
2007 StandoutNobel
Recognition and Ubiquitination of Notch by Itch, a Hect-type E3 Ubiquitin Ligase
2000
Inducible gene knockout of transcription factor recombination signal binding protein‐J reveals its essential role in T versus B lineage decision
2002 StandoutNobel
Thymic selection revisited: how essential is it?
2003
Regulation of lymphocyte development by Notch signaling
2007 StandoutNobel
Notch regulation of lymphocyte development and function
2004
Chronic Treatment with the γ-Secretase Inhibitor LY-411,575 Inhibits β-Amyloid Peptide Production and Alters Lymphopoiesis and Intestinal Cell Differentiation
2004
Eater, a Transmembrane Protein Mediating Phagocytosis of Bacterial Pathogens in Drosophila
2005 StandoutNobel
Corneal Epithelial Cell Fate Is Maintained during Repair by Notch1 Signaling via the Regulation of Vitamin A Metabolism
2007
<i>Jagged1</i> Ablation Results in Cerebellar Granule Cell Migration Defects and Depletion of Bergmann Glia
2006
Rescue of the Cardiac Defect in ErbB2 Mutant Mice Reveals Essential Roles of ErbB2 in Peripheral Nervous System Development
1999
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
2003 StandoutNatureNobel
Design of biologically active binary protein 2D materials
2021 StandoutNatureNobel
Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells
2023 StandoutNobel
Notch1 functions as a tumor suppressor in mouse skin
2003
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
A role for Wnt signalling in self-renewal of haematopoietic stem cells
2003 StandoutNature
Cell Cycle Arrest and Apoptosis Induced by Notch1 in B Cells
2000
Direct induction of T lymphocyte-specific gene expression by the mammalian Notch signaling pathway
2002
Notch and the Immune System
1999
VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism
2002 Nature
Inactivation of Notch1 in immature thymocytes does not perturb CD4 or CD8 T cell development
2001
Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
2010 StandoutNature
A new paradigm for hematopoietic cell lineages: revision of the classical concept of the myeloid–lymphoid dichotomy
2009
Induction of T Cell Development from Hematopoietic Progenitor Cells by Delta-like-1 In Vitro
2002
Deceiving appearances: signaling by “dead” and “fractured” receptor protein-tyrosine kinases
2000
Vascular-specific growth factors and blood vessel formation
2000 StandoutNature
Distinct Stages of Myelination Regulated by γ-Secretase and Astrocytes in a Rapidly Myelinating CNS Coculture System
2008
NEW EMBO MEMBERS' REVIEW: The ErbB signaling network: receptor heterodimerization in development and cancer
2000 Standout
c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation
2004
Notch–RBP-J signaling is involved in cell fate determination of marginal zone B cells
2002 StandoutNobel
Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells
2009 StandoutNature
Delta-like 1 is necessary for the generation of marginal zone B cells but not T cells in vivo
2004
Instruction of Distinct CD4 T Helper Cell Fates by Different Notch Ligands on Antigen-Presenting Cells
2004 StandoutNobel
Prethymic T‐cell development defined by the expression of paired immunoglobulin‐like receptors
2005
Regulatory coding of lymphoid lineage choice by hematopoietic transcription factors
2003
Notch1 Expression in Early Lymphopoiesis Influences B versus T Lineage Determination
1999 Standout
Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance
2005
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Re(de)fining the dendritic cell lineage
2012
Genes that mediate breast cancer metastasis to lung
2005 StandoutNature
Wnt signalling in stem cells and cancer
2005 StandoutNature
Angiogenesis as a therapeutic target
2005 StandoutNature
Matrix Elasticity Directs Stem Cell Lineage Specification
2006 Standout
Signals from the Sympathetic Nervous System Regulate Hematopoietic Stem Cell Egress from Bone Marrow
2006
Notch2 Is Preferentially Expressed in Mature B Cells and Indispensable for Marginal Zone B Lineage Development
2003
Heterogeneity among DN1 Prothymocytes Reveals Multiple Progenitors with Different Capacities to Generate T Cell and Non-T Cell Lineages
2004
Notch signaling controls the generation and differentiation of early T lineage progenitors
2005
Neuregulin-1 and Human Epidermal Growth Factor Receptors 2 and 3 Play a Role in Human Lung Development In Vitro
2000
Neuregulin-4: a novel growth factor that acts through the ErbB-4 receptor tyrosine kinase
1999
Establishment of NOD-Pdcd1-/-mice as an efficient animal model of type I diabetes
2005 StandoutNobel
Embryonic development is disrupted by modest increases in vascular endothelial growth factor gene expression
2000
T cell fate specification and αβ/γδ lineage commitment
2001
Thymic Anlage Is Colonized by Progenitors Restricted to T, NK, and Dendritic Cell Lineages
2005
Essential Roles for Ankyrin Repeat and Transactivation Domains in Induction of T-Cell Leukemia by Notch1
2000
Notch 1–Deficient Common Lymphoid Precursors Adopt a B Cell Fate in the Thymus
2001
Stage-Specific and Differential Notch Dependency at the αβ and γδ T Lineage Bifurcation
2006
Growth Suppression of Pre-T Acute Lymphoblastic Leukemia Cells by Inhibition of Notch Signaling
2003
REGULATION OF LYMPHOID DEVELOPMENT, DIFFERENTIATION, AND FUNCTION BY THE NOTCH PATHWAY
2005
Differential synergy of Notch and T cell receptor signaling determines αβ versus γδ lineage fate
2006
The Protein Kinase Complement of the Human Genome
2002 StandoutScience
Notch Signaling Augments T Cell Responsiveness by Enhancing CD25 Expression
2003
Leukemia-Associated Mutations within the NOTCH1 Heterodimerization Domain Fall into at Least Two Distinct Mechanistic Classes
2006
Functional mapping of disease susceptibility loci using cell biology
2006 StandoutNobel
The stream of precursors that colonizes the thymus proceeds selectively through the early T lineage precursor stage of T cell development
2008
Notch signalling via RBP-J promotes myeloid differentiation
2000
A multipotent precursor in the thymus maps to the branching point of the T versus B lineage decision
2005
Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members
2001 StandoutNobel
Maintenance of T Cell Specification and Differentiation Requires Recurrent Notch Receptor–Ligand Interactions
2004
Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling
2007 StandoutNobel
Notch1 Deficiency Dissociates the Intrathymic Development of Dendritic Cells and T Cells
2000
Transcriptional Control of Early B Cell Development
2004
Novel TCR-Mediated Mechanisms of Notch Activation and Signaling
2017
Cancer Genome Landscapes
2013 StandoutScience
A Reassessment of the Effect of Activated Notch1 on CD4 and CD8 T Cell Development
2002
Activated Notch1 Modulates Gene Expression in B Cells Similarly to Epstein-Barr Viral Nuclear Antigen 2
2000
Epiregulin Is Not Essential for Development of Intestinal Tumors but Is Required for Protection from Intestinal Damage
2004
Notch2 Haploinsufficiency Results in Diminished B1 B Cells and a Severe Reduction in Marginal Zone B Cells
2003
Separation of Notch1 Promoted Lineage Commitment and Expansion/Transformation in Developing T Cells
2001
MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands
2010 StandoutNobel
Notch-Regulated Ankyrin-Repeat Protein Inhibits Notch1 Signaling: Multiple Notch1 Signaling Pathways Involved In T Cell Development
2003
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Cutting Edge: An Essential Role for Notch-1 in the Development of Both Thymus-Independent and -Dependent T Cells in the Gut
2000
Notch1 activation increases hematopoietic stem cell self-renewal in vivo and favors lymphoid over myeloid lineage outcome
2002
Analysis of Notch1 Function by In Vitro T Cell Differentiation of Pax5 Mutant Lymphoid Progenitors
2004
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Differential Effects of Notch Ligands Delta-1 and Jagged-1 in Human Lymphoid Differentiation
2001
Notch1 is required for neuronal and glial differentiation in the cerebellum
2002
Recombination signal sequence-binding protein Jκ alters mesodermal cell fate decisions by suppressing cardiomyogenesis
2003 StandoutNobel
Heparin-binding EGF-like growth factor accelerates keratinocyte migration and skin wound healing
2005
Works of Michelle E. E. Bauer being referenced
Deficient T Cell Fate Specification in Mice with an Induced Inactivation of Notch1
1999
ErbB3 is required for normal cerebellar and cardiac development: a comparison with ErbB2- and heregulin-deficient mice
1997