Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Hypoxia Induces Trimethylated H3 Lysine 4 by Inhibition of JARID1A Demethylase
2010
HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O 2 Sensing
2001 StandoutScienceNobel
Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist
2004 StandoutNobel
A sex-biased imbalance between Tfr, Tph, and atypical B cells determines antibody responses in COVID-19 patients
2023 StandoutNobel
PD-1 + regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer
2019 StandoutNobel
Regulation of tyrosine hydroxylase promoter activity by the von Hippel–Lindau tumor suppressor protein and hypoxia‐inducible transcription factors
2003
Regulation of Angiogenesis by Oxygen and Metabolism
2009
Transcriptional Regulation of Mitotic Checkpoint Gene MAD1 by p53
2003
Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons
2013 StandoutNobel
Differential Roles of Hypoxia-Inducible Factor 1α (HIF-1α) and HIF-2α in Hypoxic Gene Regulation
2003
Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m 6 A-demethylation of NANOG mRNA
2016 StandoutNobel
TET1-Mediated Hydroxymethylation Facilitates Hypoxic Gene Induction in Neuroblastoma
2014
The DNA-damage response in human biology and disease
2009 StandoutNature
Positive autoregulation of the myogenic determination gene MyoD1
1989
Powerful Skin Cancer Protection by a CPD-Photolyase Transgene
2005
Adjacent DNA elements dominantly restrict the ubiquitous activity of a novel chromatin-opening region to specific tissues
1997
Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a
1999
Transcriptional regulation by p53: one protein, many possibilities
2006
CeMyoD accumulation defines the body wall muscle cell fate during C. elegans embryogenesis
1990 StandoutNobel
Hypoxia, DNA repair and genetic instability
2008
Rescue of end fragments of yeast artificial chromosomes by homologous recombination in yeast
1991
Analyses of p53 Target Genes in the Human Genome by Bioinformatic and Microarray Approaches
2001
Retinoic acid receptors: From molecular mechanisms to cancer therapy
2014
p53 is a NF‐Y‐ and p21‐independent, Sp1‐dependent repressor of cyclin B1 transcription
2005
Control of the Embryonic Stem Cell State
2011
Repression of New p53 Targets Revealed by ChIP on Chip Experiments
2006
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Chromatin Unfolds
1996
Transcription-coupled DNA repair: two decades of progress and surprises
2008
Molecular basis of the VHL hereditary cancer syndrome
2002 StandoutNobel
Histone methylation: a dynamic mark in health, disease and inheritance
2012 Standout
Pathophysiological Response to Hypoxia — From the Molecular Mechanisms of Malady to Drug Discovery: Epigenetic Regulation of the Hypoxic Response via Hypoxia-Inducible Factor and Histone Modifying Enzymes
2011
The von Hippel–Lindau tumor suppressor protein
2001 StandoutNobel
Hypoxia increases genome-wide bivalent epigenetic marking by specific gain of H3K27me3
2016
Activation of muscle genes without myogenesis by ectopic expression of MyoD in frog embryo cells
1990 StandoutNatureNobel
TheXenopus laevisEstrogen Receptor: Sequence Homology with Human and Avian Receptors and Identification of Multiple Estrogen Receptor Messenger Ribonucleic Acids*
1987
Crystal structure of the nucleosome core particle at 2.8 Å resolution
1997 StandoutNature
Positional cloning of the mouse obese gene and its human homologue
1994 StandoutNature
Hypoxia causes epigenetic gene regulation in macrophages by attenuating Jumonji histone demethylase activity
2010
Regulatory phases of early liver development: paradigms of organogenesis
2002
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
Silencers and locus control regions: opposite sides of the same coin
1997
DNA Damage-Induced Downregulation of Cdc25C Is Mediated by p53 via Two Independent Mechanisms
2004
Blinded by the Light: The Growing Complexity of p53
2009 Standout
Clusterin Is a Secreted Marker for a Hypoxia-Inducible Factor-Independent Function of the von Hippel-Lindau Tumor Suppressor Protein
2006 StandoutNobel
Ubiquitin-dependent regulation of COPII coat size and function
2012 StandoutNatureNobel
Myocarditis
2011 Standout
Pioneer transcription factors: establishing competence for gene expression
2011
p53 negatively regulates the expression of FAT10, a gene upregulated in various cancers
2006
Helper T Cell Differentiation Is Controlled by the Cell Cycle
1998
The transcriptional and signalling networks of pluripotency
2011
Profile of gene expression regulated by induced p53: connection to the TGF‐β family
2000
A Universal Live Cell Barcoding-Platform for Multiplexed Human Single Cell Analysis
2018
The control of histone methylation and gene expression by oxidative stress, hypoxia, and metals
2012
Serial analysis of gene expression in renal carcinoma cells reveals VHL-dependent sensitivity to TNFα cytotoxicity
2002
HIF-1 Regulates Cytochrome Oxidase Subunits to Optimize Efficiency of Respiration in Hypoxic Cells
2007 StandoutNobel
Transcription coupled nucleotide excision repair in the yeast Saccharomyces cerevisiae: The ambiguous role of Rad26
2015
Chromatin as an oxygen sensor and active player in the hypoxia response
2011
Transcriptional Repression by p53 through Direct Binding to a Novel DNA Element
2001
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Hypoxia upregulates the histone demethylase JMJD1A via HIF-1
2008
Structural and functional conservation at the boundaries of the chicken β-globin domain
2000
Cancer-related inflammation
2008 StandoutNature
Molecular mechanisms and clinical applications of angiogenesis
2011 StandoutNature
Global transcriptional program of p53 target genes during the process of apoptosis and cell cycle progression
2003
The von Hippel-Lindau Tumor Suppressor Stabilizes Novel Plant Homeodomain Protein Jade-1
2002
Gene regulation by long non-coding RNAs and its biological functions
2020 Standout
FoxA1 directs the lineage and immunosuppressive properties of a novel regulatory T cell population in EAE and MS
2014
The Bradykinin Type 2 Receptor Is a Target for p53-mediated Transcriptional Activation
2000
KLF5 Interacts with p53 in Regulating Survivin Expression in Acute Lymphoblastic Leukemia
2006
Master Transcription Factors Determine Cell-Type-Specific Responses to TGF-β Signaling
2011
Transcriptional Repression of the Anti-apoptoticsurvivin Gene by Wild Type p53
2002
Myocarditis
2009 Standout
Regulation of the human AP-endonuclease (APE1/Ref-1) expression by the tumor suppressor p53 in response to DNA damage
2008
Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21
2015 StandoutNobel
Cytotoxic T lymphocyte antigen-4 (CTLA-4) regulates primary and secondary peptide-specific CD4+T cell responses
1999 StandoutNobel
HIF-1α is required for development of the sympathetic nervous system
2019 StandoutNobel
Single-cell transplantation determines the time when Xenopus muscle precursor cells acquire a capacity for autonomous differentiation.
1993 StandoutNobel
Structure of the STRA6 receptor for retinol uptake
2016 StandoutScienceNobel
The Steroid and Thyroid Hormone Receptor Superfamily
1988 StandoutScience
Epigenetic Regulation by Histone Demethylases in Hypoxia
2015
Chromatin and oxygen sensing in the context of JmjC histone demethylases
2014
The von Hippel-Lindau tumor suppressor protein sensitizes renal cell carcinoma cells to tumor necrosis factor-induced cytotoxicity by suppressing the nuclear factor-kappaB-dependent antiapoptotic pathway.
2003
Increase in membrane cholesterol: A possible trigger for degradation of HMG CoA reductase and crystalloid endoplasmic reticulum in UT-1 cells
1984 StandoutNobel
Transcriptional control of human p53-regulated genes
2008 Standout
p53-mediated repression of DNA methyltransferase 1 expression by specific DNA binding.
2003
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
Control of skin cancer by the circadian rhythm
2011 StandoutNobel
Two domains of MyoD mediate transcriptional activation of genes in repressive chromatin: a mechanism for lineage determination in myogenesis.
1997
pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner
2016 StandoutScienceNobel
Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells
2012 StandoutNobel
Pcid2 Inactivates Developmental Genes in Human and Mouse Embryonic Stem Cells to Sustain Their Pluripotency by Modulation of EID1 Stability
2013
von Hippel-Lindau Protein-Mediated Repression of Tumor Necrosis Factor Alpha Translation Revealed through Use of cDNA Arrays
2003
Structure of an HIF-1α-pVHL Complex: Hydroxyproline Recognition in Signaling
2002 StandoutScienceNobel
Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis
2009
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1α
2008 StandoutNobel
Membrane-bound domain of HMG CoA reductase is required for sterol-enhanced degradation of the enzyme
1985 StandoutNobel
Direct Link between RACK1 Function and Localization at the Ribosome In Vivo
2008 StandoutNobel
Endogenous von Hippel-Lindau tumor suppressor protein regulates catecholaminergic phenotype in PC12 cells.
2002
von Hippel–Lindau protein binds hyperphosphorylated large subunit of RNA polymerase II through a proline hydroxylation motif and targets it for ubiquitination
2003
Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase
2010 StandoutNobel
Promotion of direct reprogramming by transformation-deficient Myc
2010 StandoutNobel
Mevalonolactone inhibits the rate of synthesis and enhances the rate of degradation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in rat hepatocytes.
1983
A DNA insulator prevents repression of a targeted X-linked transgene but not its random or imprinted X inactivation
2006 StandoutNobel
Role ofVHLGene Mutation in Human Cancer
2004 StandoutNobel
Conservation of sequence and structure flanking the mouse and human β-globin loci: The β-globin genes are embedded within an array of odorant receptor genes
1999 StandoutNobel
ATP-sensitive potassium channel (K ATP )–dependent regulation of cardiotropic viral infections
2011 StandoutNobel
Works of Michelle Barton being referenced
Rapid monoisotopic cisplatin based barcoding for multiplexed mass cytometry
2017
Hypoxia-induced and stress-specific changes in chromatin structure and function
2007
von Hippel-Lindau Protein Induces Hypoxia-regulated Arrest of Tyrosine Hydroxylase Transcript Elongation in Pheochromocytoma Cells
1999
Hypoxia Actively Represses Transcription by Inducing Negative Cofactor 2 (Dr1/DrAP1) and Blocking Preinitiation Complex Assembly
2003
Foxa1 Functions as a Pioneer Transcription Factor at Transposable Elements to Activate Afp during Differentiation of Embryonic Stem Cells
2010
p53 Regulates Cell Cycle and MicroRNAs to Promote Differentiation of Human Embryonic Stem Cells
2012
Ronin/Hcf-1 binds to a hyperconserved enhancer element and regulates genes involved in the growth of embryonic stem cells
2010
Site-directed, recombination-mediated mutagenesis of a complex gene locus
1990
TRIM24 links a non-canonical histone signature to breast cancer
2010 Nature
LncPRESS1 Is a p53-Regulated LncRNA that Safeguards Pluripotency by Disrupting SIRT6-Mediated De-acetylation of Histone H3K56
2016
Hypoxia induces a novel signature of chromatin modifications and global repression of transcription
2008
Hepatocyte Nuclear Factor 3 Relieves Chromatin-mediated Repression of the α-Fetoprotein Gene
1999
Eosinophilic Myocarditis Temporally Associated With Conjugate Meningococcal C and Hepatitis B Vaccines in Children
2008
p53-Mediated Repression of Alpha-Fetoprotein Gene Expression by Specific DNA Binding
1999
Production and characterization of monoclonal antibodies to rat liver microsomal 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
1982
The erythroid protein cGATA-1 functions with a stage-specific factor to activate transcription of chromatin-assembled beta-globin genes.
1993
A Direct Intersection between p53 and Transforming Growth Factor β Pathways Targets Chromatin Modification and Transcription Repression of the α-Fetoprotein Gene
2005
UV-induced inhibition of transcription involves repression of transcription initiation and phosphorylation of RNA polymerase II
2000
Regulated expression of the beta-globin gene locus in synthetic nuclei.
1994
Estrogen induces transcription of the Xenopus laevis serum retinol-binding protein gene.
1987
Transcription Factor Interactions and Chromatin Modifications Associated with p53-Mediated, Developmental Repression of the Alpha-Fetoprotein Gene
2005
Chromatin-Bound p53 Anchors Activated Smads and the mSin3A Corepressor To Confer Transforming Growth Factor β-Mediated Transcription Repression
2008
Transient administration of estradiol-17 beta establishes an autoregulatory loop permanently inducing estrogen receptor mRNA.
1988