Standout Papers

The amyloid state and its association with protein misfolding diseas... 2009 2026 2014 2020 1.8k
  1. The amyloid state and its association with protein misfolding diseases (2014)
    Tuomas P. J. Knowles, Michele Vendruscolo et al. Nature Reviews Molecular Cell Biology
  2. Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism (2013)
    Samuel I. A. Cohen, Sara Linse et al. Proceedings of the National Academy of Sciences
  3. The Amyloid-β Pathway in Alzheimer’s Disease (2021)
    Harald Hampel, John Hardy et al. Molecular Psychiatry
  4. An Analytical Solution to the Kinetics of Breakable Filament Assembly (2009)
    Tuomas P. J. Knowles, Christopher A. Waudby et al. Science
  5. Parmbsc1: a refined force field for DNA simulations (2015)
    Iván Ivani, Pablo D. Dans et al. Nature Methods
  6. Role of Intermolecular Forces in Defining Material Properties of Protein Nanofibrils (2007)
    Tuomas P. J. Knowles, Anthony W. P. Fitzpatrick et al. Science
  7. Mapping Long-Range Interactions in α-Synuclein using Spin-Label NMR and Ensemble Molecular Dynamics Simulations (2004)
    Matthew M. Dedmon, Kresten Lindorff‐Larsen et al. Journal of the American Chemical Society
  8. Simultaneous determination of protein structure and dynamics (2005)
    Kresten Lindorff‐Larsen, Robert B. Best et al. Nature Cell Biology
  9. Molecular mechanisms of protein aggregation from global fitting of kinetic models (2016)
    Georg Meisl, Julius B. Kirkegaard et al. Nature Protocols
  10. Amyloid-like Aggregates Sequester Numerous Metastable Proteins with Essential Cellular Functions (2011)
    Heidi Olzscha, Andreas C. Woerner et al. Cell
  11. Solution conditions determine the relative importance of nucleation and growth processes in α-synuclein aggregation (2014)
    Alexander K. Buell, Céline Galvagnion et al. Proceedings of the National Academy of Sciences
  12. Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers (2017)
    Giuliana Fusco, Serene W. Chen et al. Science
  13. Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation (2015)
    Céline Galvagnion, Alexander K. Buell et al. Nature Chemical Biology
  14. Prediction of “Aggregation-prone” and “Aggregation-susceptible” Regions in Proteins Associated with Neurodegenerative Diseases (2005)
    Amol Pawar, Jesús Zurdo et al. Journal of Molecular Biology
  15. Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms (2019)
    Suman De, David C. Wirthensohn et al. Nature Communications
  16. Dynamics of oligomer populations formed during the aggregation of Alzheimer’s Aβ42 peptide (2020)
    Thomas C. T. Michaels, Anđela Šarić et al. Nature Chemistry
  17. Misfolded protein oligomers: mechanisms of formation, cytotoxic effects, and pharmacological approaches against protein misfolding diseases (2024)
    Fabrizio Chiti, Michele Vendruscolo et al. Molecular Neurodegeneration

Immediate Impact

13 by Nobel laureates 44 from Science/Nature 113 standout
Sub-graph 1 of 17

Citing Papers

Stress response silencing by an E3 ligase mutated in neurodegeneration
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A cytosolic surveillance mechanism activates the mitochondrial UPR
2023 StandoutNature
2 intermediate papers

Works of Michele Vendruscolo being referenced

Cytosolic aggregation of mitochondrial proteins disrupts cellular homeostasis by stimulating the aggregation of other proteins
2021
Widespread Proteome Remodeling and Aggregation in Aging C. elegans
2015
and 7 more

Author Peers

Author Last Decade Papers Cites
Michele Vendruscolo 28961 13607 7947 562 40.5k
David Eisenberg 45622 12033 9841 404 60.7k
Vladimir N. Uversky 50938 10686 13737 1.1k 71.7k
Tuomas P. J. Knowles 18790 14500 3917 461 31.8k
Roland Riek 16991 8080 3296 278 24.8k
Anthony L. Fink 17604 9033 4640 229 28.3k
Jeffery W. Kelly 28496 11543 3391 418 39.1k
Sara Linse 14383 9002 5277 338 26.9k
Peter T. Lansbury 17957 16702 2144 222 34.8k
Fabrizio Chiti 16267 11220 3488 182 21.7k
M.R. Sawaya 21025 7226 4311 240 27.4k

All Works

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2026