Standout Papers

Role of the Ubiquitin-Proteasome Pathway in Regulating Abundance of the Cyclin-Depend... 1992 2026 2003 2014 1.6k
  1. Role of the Ubiquitin-Proteasome Pathway in Regulating Abundance of the Cyclin-Dependent Kinase Inhibitor p27 (1995)
    Michele Pagano, Sun W. Tam et al. Science
  2. Cyclin D1 is a nuclear protein required for cell cycle progression in G1. (1993)
    Véronique Baldin, Jiří Lukáš et al. Genes & Development
  3. SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27 (1999)
    Andrea C. Carrano, Esther Eytan et al. Nature Cell Biology
  4. Structure of the Cul1–Rbx1–Skp1–F boxSkp2 SCF ubiquitin ligase complex (2002)
    Ning Zheng, Brenda A. Schulman et al. Nature
  5. Cyclin A is required at two points in the human cell cycle. (1992)
    Michele Pagano, Rainer Pepperkok et al. The EMBO Journal
  6. Human Cyclin E, a Nuclear Protein Essential for the G1-to-S Phase Transition (1995)
    Motoaki Ohtsubo, Anne M. Theodoras et al. Molecular and Cellular Biology
  7. Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas (1997)
    Massimo Loda, Barry Cukor et al. Nature Medicine
  8. The SCF ubiquitin ligase: insights into a molecular machine (2004)
    Timothy Cardozo, Michele Pagano Nature Reviews Molecular Cell Biology
  9. Deregulated proteolysis by the F-box proteins SKP2 and β-TrCP: tipping the scales of cancer (2008)
    David Frescas, Michele Pagano Nature reviews. Cancer
  10. Regulation of the Cdk inhibitor p27 and its deregulation in cancer (2000)
    Joyce M. Slingerland, Michele Pagano Journal of Cellular Physiology
  11. S6K1- and ßTRCP-Mediated Degradation of PDCD4 Promotes Protein Translation and Cell Growth (2006)
    N. Valerio Dorrello, Angelo Peschiaroli et al. Science
  12. The F-box protein family. (2000)
    Edward T. Kipreos, Michele Pagano Genome Biology
  13. Mechanisms and function of substrate recruitment by F-box proteins (2013)
    Jeffrey R. Skaar, Julia K. Pagan et al. Nature Reviews Molecular Cell Biology
  14. Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation (1999)
    A. Montagnoli, Frédéric Di Fiore et al. Genes & Development
  15. Nrf2 Activation Promotes Lung Cancer Metastasis by Inhibiting the Degradation of Bach1 (2019)
    Luca Lignitto, Sarah E. LeBoeuf et al. Cell
  16. The cell-cycle regulatory protein Cks1 is required for SCFSkp2-mediated ubiquitinylation of p27 (2001)
    Dvora Ganoth, Gil Bornstein et al. Nature Cell Biology
  17. Role of the SCFSkp2 Ubiquitin Ligase in the Degradation of p21Cip1 in S Phase (2003)
    Gil Bornstein, Joanna Bloom et al. Journal of Biological Chemistry
  18. Degradation of Cdc25A by β-TrCP during S phase and in response to DNA damage (2003)
    Luca Busino, Maddalena Donzelli et al. Nature

Immediate Impact

25 by Nobel laureates 51 from Science/Nature 139 standout
Sub-graph 1 of 16

Citing Papers

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1 intermediate paper

Works of Michele Pagano being referenced

USP33 regulates centrosome biogenesis via deubiquitination of the centriolar protein CP110
2013 Nature
SCF ubiquitin ligases in the maintenance of genome stability
2011
and 2 more

Author Peers

Author Last Decade Papers Cites
Michele Pagano 27686 16059 6972 451 42.0k
Lance A. Liotta 34161 16682 6021 650 61.2k
Joseph R. Nevins 28518 15981 2785 279 38.7k
Harold Varmus 32046 13020 2519 381 55.3k
Claus Garbe 14755 20753 2092 730 33.4k
Joe W. Gray 26319 11338 3906 469 45.4k
Paul S. Meltzer 22087 9027 1744 378 35.0k
Lars Juhl Jensen 47759 5318 3776 232 71.9k
Mien‐Chie Hung 42788 27578 5010 740 66.0k
David W. Russell 29215 7866 3806 522 51.7k
Jeffrey M. Trent 20147 7246 1955 377 30.9k

All Works

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