Citation Impact
Citing Papers
Generation of knock-in primary human T cells using Cas9 ribonucleoproteins
2015 StandoutNobel
A Phase I Pharmacokinetic and Biological Correlative Study of IMP321, a Novel MHC Class II Agonist, in Patients with Advanced Renal Cell Carcinoma
2009
Metalloproteases regulate T‐cell proliferation and effector function via LAG‐3
2007
LAG-3 Regulates Plasmacytoid Dendritic Cell Homeostasis
2009
MART-1 peptide vaccination plus IMP321 (LAG-3Ig fusion protein) in patients receiving autologous PBMCs after lymphodepletion: results of a Phase I trial
2014
Crystal Structure and Mechanism of Activation of TANK-Binding Kinase 1
2013
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
Temporally regulated nuclear entry of the Drosophila period protein contributes to the circadian clock
1995 StandoutNobel
GM-CSF Gene-Modifed Cancer Cell Immunotherapies: Of Mice and Men
2006
Hormone Interactions to Leu-rich Repeats in the Gonadotropin Receptors
2001
Requirement forPeriodGene Expression in the Adult and Not During Development for Locomotor Activity Rhythms of ImaginalDrosophila Melanogaster
1990 StandoutNobel
The leucine-rich repeat structure
2008
Hormone Interactions to Leu-rich Repeats in the Gonadotropin Receptors
2001
Ligand-induced receptor dimerization may be critical for signal transduction by choriogonadotropin
1997
A phase I study of IMP321 and gemcitabine as the front-line therapy in patients with advanced pancreatic adenocarcinoma
2012
Molecular Cloning, Genomic Organization, and Developmental Regulation of a Novel Receptor from Drosophila melanogaster Structurally Related to Members of the Thyroid-stimulating Hormone, Follicle-stimulating Hormone, Luteinizing Hormone/Choriogonadotropin Receptor Family from Mammals
1997
Clusters of Resistance Genes in Plants Evolve by Divergent Selection and a Birth-and-Death Process
1998
Hypoxia and Inflammation
2011 Standout
NF-κB, the first quarter-century: remarkable progress and outstanding questions
2012 Standout
The inhibitory cytokine IL-35 contributes to regulatory T-cell function
2007 StandoutNature
Cell death and proliferation in acute slices and organotypic cultures of mammalian CNS
2009
Targeting NF- B activation via pharmacologic inhibition of IKK2-induced apoptosis of human acute myeloid leukemia cells
2004
Circadian Pacemakers Blowing Hot and Cold—But They're Clocks, Not Thermometers
1997 StandoutNobel
A promoterless period gene mediates behavioral rhythmicity and cyclical per expression in a restricted subset of the drosophila nervous system
1994 StandoutNobel
Hormone Interactions to Leu-rich Repeats in the Gonadotropin Receptors
2001
IKK/NF- B signaling: balancing life and death - a new approach to cancer therapy
2005 Standout
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
Wnt/β-Catenin Signaling and Disease
2012 Standout
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
The Ectodomain of the Luteinizing Hormone Receptor Interacts with Exoloop 2 to Constrain the Transmembrane Region
2002 StandoutNobel
New drugs in multiple myeloma: mechanisms of action and phase I/II clinical findings
2008
Soluble Interleukin-6 (IL-6) Receptor/IL-6 Fusion Protein Enhances in Vitro Differentiation of Purified Rat Oligodendroglial Lineage Cells
2002
Molecular Cloning, Genomic Organization, Developmental Regulation, and a Knock-out Mutant of a Novel Leu-rich Repeats-containing G Protein-coupled Receptor (DLGR-2) from Drosophila melanogaster
2000
Plant pathogens and integrated defence responses to infection
2001 StandoutNature
Assembly of an adult type acetylcholine receptor in a mouse cell line transfected with rat muscle ϵ‐subunit DNA
1990 StandoutNobel
The evolution of checkpoint blockade as a cancer therapy: what's here, what's next?
2015
The Three Subfamilies of Leucine-Rich Repeat-Containing G Protein-Coupled Receptors (LGR): Identification of LGR6 and LGR7 and the Signaling Mechanism for LGR7
2000
NF-κB and cancer — identifying targets and mechanisms
2008
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
EMT: 2016
2016 Standout
Lag-3, Tim-3, and TIGIT: Co-inhibitory Receptors with Specialized Functions in Immune Regulation
2016 Standout
Cancer immunotherapy comes of age
2011 StandoutNature
The blockade of immune checkpoints in cancer immunotherapy
2012 Standout
Activation of the Luteinizing Hormone Receptor Following Substitution of Ser-277 with Selective Hydrophobic Residues in the Ectodomain Hinge Region
2000 StandoutNobel
LAG-3 in Cancer Immunotherapy
2010
The Role of the Hinge Region of the Luteinizing Hormone Receptor in Hormone Interaction and Signal Generation
2001
Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade
2017 StandoutNobel
Inhibition of NF-κB by Sodium Salicylate and Aspirin
1994 StandoutScience
Phenotypic analysis of the murine CD4-related glycoprotein, CD223 (LAG-3)
2002
Costimulatory and Coinhibitory Receptor Pathways in Infectious Disease
2016
Co-expression of Defective Luteinizing Hormone Receptor Fragments Partially Reconstitutes Ligand-induced Signal Generation
1997 StandoutNobel
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
2015 StandoutNature
Immune Checkpoint Blockade: A Common Denominator Approach to Cancer Therapy
2015 Standout
A selective novel low‐molecular‐weight inhibitor of IκB kinase‐β (IKK‐β) prevents pulmonary inflammation and shows broad anti‐inflammatory activity
2005
Identification of stem cells in small intestine and colon by marker gene Lgr5
2007 StandoutNature
A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application
2013 StandoutNobel
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
NF-κB, inflammation, immunity and cancer: coming of age
2018 Standout
Coexpression of CD49b and LAG-3 identifies human and mouse T regulatory type 1 cells
2013
Biochemical Analysis of the Regulatory T Cell Protein Lymphocyte Activation Gene-3 (LAG-3; CD223)
2004
Characterization of Two LGR Genes Homologous to Gonadotropin and Thyrotropin Receptors with Extracellular Leucine-Rich Repeats and a G Protein-Coupled, Seven-Transmembrane Region
1998
SPAS-1 (stimulator of prostatic adenocarcinoma-specific T cells)/SH3GLB2: A prostate tumor antigen identified by CTLA-4 blockade
2008 StandoutNobel
CD4+CD25−LAG3+regulatory T cells controlled by the transcription factor Egr-2
2009 StandoutNobel
Nods, Nalps and Naip: intracellular regulators of bacterial-induced inflammation
2003
Circadian oscillations in period gene mRNA levels are transcriptionally regulated.
1992 StandoutNobel
PER Protein Interactions and Temperature Compensation of a Circadian Clock in Drosophila
1995 StandoutScienceNobel
Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model
2016 StandoutNobel
THE LUTEINIZING HORMONE RECEPTOR
1998
PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice
2011 StandoutNobel
CD3/TCR Complex-Associated Lymphocyte Activation Gene-3 Molecules Inhibit CD3/TCR Signaling
1998
Coordinate changes in heat shock element-binding activity and HSP70 gene transcription rates in human cells.
1988
Molecular coevolution within a Drosophila clock gene
1998 StandoutNobel
Activation of Orphan Receptors by the Hormone Relaxin
2002 StandoutScience
Fundamental Mechanisms of Immune Checkpoint Blockade Therapy
2018 StandoutNobel
The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex
2009 StandoutNature
Inflammatory Blockade Restores Adult Hippocampal Neurogenesis
2003 StandoutScience
Maturation and Activation of Dendritic Cells Induced by Lymphocyte Activation Gene-3 (CD223)
2002
The future of immune checkpoint therapy
2015 StandoutScienceNobel
Phase Shifting of the Circadian Clock by Induction of the Drosophila period Protein
1994 StandoutScienceNobel
A post-transcriptional mechanism contributes to circadian cycling of a per-beta-galactosidase fusion protein.
1991 StandoutNobel
T cell exclusion, immune privilege, and the tumor microenvironment
2015 StandoutScience
Cutting Edge: Molecular Analysis of the Negative Regulatory Function of Lymphocyte Activation Gene-3
2002
Multiple Myeloma
2011 Standout
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Antiproliferative prostaglandins activate heat shock transcription factor.
1992
Negative Regulation of T Cell Homeostasis by Lymphocyte Activation Gene-3 (CD223)
2005
Chemical Implications for Antitumor and Antiviral Prostaglandins: Reaction of Δ7-Prostaglandin A1 and Prostaglandin A1 Methyl Esters with Thiols
1997 StandoutNobel
Works of Michel Dréano being referenced
Prevention of neuron and oligodendrocyte degeneration by interleukin-6 (IL-6) and IL-6 receptor/IL-6 fusion protein in organotypic hippocampal slices
2003
Structural predictions for the ligand-binding region of glycoprotein hormone receptors and the nature of hormone–receptor interactions
1995
Crystal structure of inhibitor of κB kinase β
2011 Nature
Neuroprotective effect of interleukin‐6 and IL6/IL6R chimera in the quinolinic acid rat model of Huntington's syndrome
2001
AS602868, a pharmacological inhibitor of IKK2, reveals the apoptotic potential of TNF-α in Jurkat leukemic cells
2003
Targeting NF‐κB pathway with an IKK2 inhibitor induces inhibition of multiple myeloma cell growth
2007
Lymphocyte activation gene-3 induces tumor regression and antitumor immune responses
1999
IKK2 Inhibitor Alleviates Kidney and Wasting Diseases in a Murine Model of Human AIDS
2004
Characterization of the major histocompatibility complex class II binding site on LAG-3 protein
1997
Organization of the Drosophila melanogaster hsp7O Heat Shock Regulation Unit
1987
Organization of the Drosophila melanogaster hsp70 heat shock regulation unit.
1987
Production of Secretable Proteins Using the Passage In Vivo as Tumours of Cells Carrying Heat-Inducible Expression Constructs
1988
High-level, heat-regulated synthesis of proteins in eukaryotic cells
1986