Citation Impact
Citing Papers
Anti-Markovnikov alkene oxidation by metal-oxo–mediated enzyme catalysis
2017 StandoutScienceNobel
Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation
2015 StandoutNobel
Long-Term Monitoring of Bacteria Undergoing Programmed Population Control in a Microchemostat
2005 StandoutScienceNobel
Metagenomic Analysis of the Human Distal Gut Microbiome
2006 StandoutScience
Application of in situ product-removal techniques to biocatalytic processes
1999
Industrial biocatalysis today and tomorrow
2001 StandoutNature
Catalytic Asymmetric Three‐Component Synthesis of Homoallylic Amines
2013 StandoutNobel
Recent advances in the catalytic asymmetric synthesis of β-amino acids
2010 StandoutNobel
Asymmetric Counteranion‐Directed Catalysis for the Epoxidation of Enals
2007 StandoutNobel
DNA-based asymmetric catalysis
2010 StandoutNobel
Microbial electrosynthesis — revisiting the electrical route for microbial production
2010
In vitro pharmacology of cryptophycin 52 (LY355703) in human tumor cell lines
1999
Selection and evolution of enzymes from a partially randomized non-catalytic scaffold
2007 StandoutNatureNobel
Membrane‐aerated microbioreactor for high‐throughput bioprocessing
2004
Combinatorial and computational challenges for biocatalyst design
2001 StandoutNatureNobel
Interaction of cryptophycin 1 with tubulin and microtubules
1995
Development of a multiplexed microbioreactor system for high-throughput bioprocessing
2005
Drug development from marine natural products
2008 Standout
Industrial Methods for the Production of Optically Active Intermediates
2004
The ecology and biotechnology of sulphate-reducing bacteria
2008 Standout
Cells on chips
2006 StandoutNature
Expanding the Enzyme Universe: Accessing Non‐Natural Reactions by Mechanism‐Guided Directed Evolution
2015 StandoutNobel
Cryptophycin 1 binds to tubulin at a site distinct from the colchicine binding site and at a site that may overlap the vinca binding site
1996
A Self‐Sufficient Peroxide‐Driven Hydroxylation Biocatalyst
2003 StandoutNobel
Semi-synthetic DNA shuffling of aveC leads to improved industrial scale production of doramectin by Streptomyces avermitilis
2005
Improving enzymes by using them in organic solvents
2001 StandoutNature
Metabolic Interactions Between Methanogenic Consortia and Anaerobic Respiring Bacteria
2003
High-throughput screening of enzyme libraries
2000
CH Activation: A Complementary Tool in the Total Synthesis of Complex Natural Products
2012
Cryptophycins-309, 249 and other cryptophycin analogs: Preclinical efficacy studies with mouse and human tumors
2005
Liver Failure and Death after Exposure to Microcystins at a Hemodialysis Center in Brazil
1998 Standout
Enantioselective Enzymes by Computational Design and In Silico Screening
2015 StandoutNobel
Phase I and pharmacological studies of the cryptophycin analogue LY355703 administered on a single intermittent or weekly schedule
2002
Phase 2 study of cryptophycin 52 ( LY355703) in patients previously treated with platinum based chemotherapy for advanced non-small cell lung cancer
2003
Towards High‐Performance Lewis Acid Organocatalysis
2014 StandoutNobel
A marine microbial consortium apparently mediating anaerobic oxidation of methane
2000 StandoutNature
Direct Visual Detection of the Stereoselectivity of a Catalytic Reaction
2004 StandoutNobel
DNA‐Templated Organic Synthesis: Nature's Strategy for Controlling Chemical Reactivity Applied to Synthetic Molecules
2004 Standout
Cyanobacteria secondary metabolites—the cyanotoxins
1992 Standout
Strategies and challenges for the next generation of therapeutic antibodies
2010
Synthesis of Heterobifunctional Protein Fusions Using Copper‐Free Click Chemistry and the Aldehyde Tag
2012 StandoutNobel
Metabolic interactions between anaerobic bacteria in methanogenic environments
1994
A genetic basis for Pseudomonas aeruginosa biofilm antibiotic resistance
2003 StandoutNature
Engineering the third wave of biocatalysis
2012 StandoutNature
Laboratory Evolution of Toluene Dioxygenase To Accept 4-Picoline as a Substrate
2001 StandoutNobel
Total Synthesis of Cryptophycins-1, -3, -4, -24 (Arenastatin A), and -29, Cytotoxic Depsipeptides from Cyanobacteria of the Nostocaceae
1999
3d Transition Metals for C–H Activation
2018 Standout
Rhodium-Catalyzed Enantioselective Hydrogenation of β-Phthalimide Acrylates to Synthesis of β2-Amino Acids
2006
Application of biocatalysis and biotransformations to the synthesis of pharmaceuticals
1997
Phase I trial of the cryptophycin analogue LY355703 administered as an intravenous infusion on a day 1 and 8 schedule every 21 days.
2002
Practical routes to the triarylsulfonyl chloride intermediate of a β3 adrenergic receptor agonist
2003
Improving Protein Expression, Stability, and Function with ProteinMPNN
2024 StandoutNobel
Drug Discovery and Natural Products: End of an Era or an Endless Frontier?
2009 StandoutScience
Grating‐coupled surface plasmon resonance: A cell and protein microarray platform
2005
Biodiesel from microalgae
2007 Standout
Host-Bacterial Mutualism in the Human Intestine
2005 StandoutScience
Particle‐tethered NADH for production of methanol from CO2 catalyzed by coimmobilized enzymes
2007
Arenastatin A, a potent cytotoxic depsipeptide from the okinawan marine sponge Dysidea arenaria
1994
Advances in the Enzymatic Reduction of Ketones
2007
A General Approach to the Synthesis of β2‐Amino Acid Derivatives via Highly Efficient Catalytic Asymmetric Hydrogenation of α‐Aminomethylacrylates
2010
A Convergent Synthesis of (+)-Cryptophycin B, a Potent Antitumor Macrolide from Nostoc sp. Cyanobacteria
2000
Interactions of the Sponge-Derived Antimitotic Tripeptide Hemiasterlin with Tubulin: Comparison with Dolastatin 10 and Cryptophycin 1
1999
Conversion of Wastes into Bioelectricity and Chemicals by Using Microbial Electrochemical Technologies
2012 StandoutScience
Development of the First Menthane‐Based Chiral Bis(π‐allylpalladium) Catalysis: Asymmetric Allylation of Imines
2012
Extremely Active Organocatalysts Enable a Highly Enantioselective Addition of Allyltrimethylsilane to Aldehydes
2016 StandoutNobel
Directed evolution: Past, present, and future
2012
Commensal Host-Bacterial Relationships in the Gut
2001 StandoutScience
The Neber Route to Substituted Indoles
2006
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Highly Enantioselective Organocatalytic Biginelli Reaction
2006
Synthesis and Applications of β-Aminocarboxylic Acids Containing a Cyclopropane Ring
2003
Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds
2011 Standout
Dioxygen Activation at Mononuclear Nonheme Iron Active Sites: Enzymes, Models, and Intermediates
2004 Standout
Chiral Bis-π-allylpalladium Complex Catalyzed Asymmetric Allylation of Imines: Enhancement of the Enantioselectivity and Chemical Yield in the Presence of Water
2003
Highly Enantioselective Conjugate Addition of Dialkylzinc Reagents to Acyclic Nitroalkenes: A Catalytic Route to β2-Amino Acids, Aldehydes, and Alcohols
2003 StandoutNobel
Diastereoselective Allylation of Carbonyl Compounds and Imines: Application to the Synthesis of Natural Products
2013 Standout
Substrate specificity and stereospecificity of limonene-1,2-epoxide hydrolase from Rhodococcus erythropolis DCL14; an enzyme showing sequential and enantioconvergent substrate conversion
1999
Diffusion of the Interspecies Electron Carriers H 2 and Formate in Methanogenic Ecosystems and Its Implications in the Measurement of K m for H 2 or Formate Uptake
1989
Small-Molecule H-Bond Donors in Asymmetric Catalysis
2007 Standout
Catalytic Asymmetric Synthesis of Unprotected β2-Amino Acids
2021 StandoutNobel
Enantioenriched Compounds via Enzyme-Catalyzed Redox Reactions
2011
The dioxygenase-catalysed formation of vicinal cis-diols
1998
Surface Plasmon Resonance Sensors for Detection of Chemical and Biological Species
2008 Standout
The Generation of Dihydropyrimidine Libraries Utilizing Biginelli Multicomponent Chemistry
2003
Recent advances in enantioselective copper-catalyzed 1,4-addition
2009 StandoutNobel
Microbial Biofilms: from Ecology to Molecular Genetics
2000 Standout
Cocatalysts for Selective Photoreduction of CO2into Solar Fuels
2019 Standout
Metabolic Commensalism and Competition in a Two-Species Microbial Consortium
2002
Development of a Biocatalytic Process as an Alternative to the (−)-DIP-Cl-Mediated Asymmetric Reduction of a Key Intermediate of Montelukast
2009
Total Synthesis of Cryptophycins via a Chemoenzymatic Approach
1996
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Sulfate reduction in methanogenic bioreactors
1994
Engineered bidirectional communication mediates a consensus in a microbial biofilm consortium
2007 StandoutNobel
Industrial biotechnology—the future of green chemistry?
2011
Biocatalytic Synthesis of Chiral Alcohols and Amino Acids for Development of Pharmaceuticals
2013
Stronger Brønsted Acids
2007 Standout
Industrielle Verfahren zur Herstellung von optisch aktiven Zwischenprodukten
2004
Works of Michel Chartrain being referenced
Microbial Conversion of Indene to Indandiol: A Key Intermediate in the Synthesis of CRIXIVAN
1999
Application of multi‐parameter flow cytometry using fluorescent probes to study substrate toxicity in the indene bioconversion
2002
Metabolic engineering and directed evolution for the production of pharmaceuticals
2000
Biocatalysis for Pharmaceuticals—Status and Prospects for a Key Technology
2000
Development and Production of Commercial Therapeutic Monoclonal Antibodies in Mammalian Cell Expression Systems: An Overview of the Current Upstream Technologies
2008
An Asymmetric Synthesis of L-694,458, a Human Leukocyte Elastase Inhibitor, via Novel Enzyme Resolution of β-Lactam Esters
1996
Microbial Ecophysiology of Whey Biomethanation: Characterization of Bacterial Trophic Populations and Prevalent Species in Continuous Culture
1986
Bioconversion of indene to cis (1S,2R) indandiol and trans (1R,2R) indandiol by Rhodococcus species
1998
Control of Interspecies Electron Flow during Anaerobic Digestion: Role of Floc Formation in Syntrophic Methanogenesis
1988
Asymmetric Biosynthesis of Key Aromatic Intermediates in the Synthesis of an Endothelin Receptor Antagonist
2001
Efficient synthesis of the optically active dihydropyrimidinone of a potent α1A- selective adrenoceptor antagonist
2002
Conversion of indene to cis -(1 S ),(2 R )-indandiol by mutants of Pseudomonas putida F1
1997
Asymmetric bioreduction of a β-ketoester to (R)-β-hydroxyester by the fungus Mortierella alpina MF 5534
1995
Asymmetric bioreduction of a β-tetralone to its corresponding (S)-alcohol by the yeast Trichosporon capitatum MY 1890
1996
Asymmetric bioreduction of (2-(4-nitro-phenyl)-N-(2-oxo-2-pyridin-3-yl-ethyl)-acetamide) to its corresponding (R) alcohol [(R)-N- (2-hydroxy-2-pyridin-3-yl-ethyl)-2-(4-nitro-phenyl)-acetamide] by using Candida sorbophila MY 1833
1999
Chiral bio-resolution of racemic indene oxide by fungal epoxide hydrolases
1995
Asymmetric bioreductions: application to the synthesis of pharmaceuticals
2001
Evaluation of an electrochemical bioreactor system in the biotransformation of 6-bromo-2-tetralone to 6-bromo-2-tetralol
2001
Pharmaceuticals from cultured algae
1990
Asymmetric bioreduction of a keto ester to its corresponding (S)-hydroxy ester by Microbacterium sp. MB 5614
1996
Practical chemoenzymatic synthesis of a 3-pyridylethanolamino β3 adrenergic receptor agonist
1999