Citation Impact
Citing Papers
PKA phosphorylation couples hepatic inositol-requiring enzyme 1α to glucagon signaling in glucose metabolism
2011
XBP1s Is an Anti-lipogenic Protein
2016
Potential for therapeutic manipulation of the UPR in disease
2013
Unfolded Protein Response Signaling and Metabolic Diseases
2013
A novel missense mutation causing abnormal LMAN1 in a Japanese patient with combined deficiency of factor V and factor VIII
2009
Crystal structure of the LMAN1‐CRD/MCFD2 transport receptor complex provides insight into combined deficiency of factor V and factor VIII
2010
Mechanisms, regulation and functions of the unfolded protein response
2020 Standout
Terminal differentiation of spontaneous rheumatoid factor–secreting B cells from rheumatoid arthritis patients depends on endogenous interleukin‐1 0
1995
mTOR Signaling in Growth Control and Disease
2012 Standout
Hepatic Bax Inhibitor-1 Inhibits IRE1α and Protects from Obesity-associated Insulin Resistance and Glucose Intolerance
2009
Inflammatory links between obesity and metabolic disease
2011 Standout
The contribution made bySchistosomainfection to non-traumatic disorders of the spinal cord in Malawi
2003
Lipid Droplets as Immune Modulators in Myeloid Cells
2018
Brown and beige fat: development, function and therapeutic potential
2013 Standout
A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
2012 StandoutNature
Intestinal homeostasis and its breakdown in inflammatory bowel disease
2011 StandoutNature
New insights into ER stress-induced insulin resistance
2012
Autophagy and the Integrated Stress Response
2010 Standout
Ulcerative Colitis
2011 Standout
ACSL3 and GSK‐3β are essential for lipid upregulation induced by endoplasmic reticulum stress in liver cells
2010
ER Stress Cooperates with Hypernutrition to Trigger TNF-Dependent Spontaneous HCC Development
2014
Human schistosomiasis
2006 Standout
The chemical chaperone 4-phenylbutyrate inhibits adipogenesis by modulating the unfolded protein response
2009
Dissociation of Inositol-requiring Enzyme (IRE1α)-mediated c-Jun N-terminal Kinase Activation from Hepatic Insulin Resistance in Conditional X-box-binding Protein-1 (XBP1) Knock-out Mice
2011
Hallmarks of aging: An expanding universe
2023 Standout
The unfolded protein response: controlling cell fate decisions under ER stress and beyond
2012 Standout
The contribution of endoplasmic reticulum stress to liver diseases
2011
Treatment of Obesity with Celastrol
2015 Standout
The Unfolded Protein Response Mediates Adaptation to Exercise in Skeletal Muscle through a PGC-1α/ATF6α Complex
2011
Atherosclerosis: current pathogenesis and therapeutic options
2011 Standout
Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis
2009
Type 2 diabetes as an inflammatory disease
2011 Standout
Adaptive suppression of the ATF4–CHOP branch of the unfolded protein response by toll-like receptor signalling
2009
Mechanisms of NAFLD development and therapeutic strategies
2018 Standout
Two to Tango: Regulation of Mammalian Iron Metabolism
2010 Standout
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Endoplasmic reticulum stress and atherosclerosis
2010
Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
2010 Standout
Dynamics and functions of lipid droplets
2018 Standout
Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain
2020 StandoutNobel
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
2018 StandoutNobel
Glycogen synthase kinase 3β inhibitors prevent hepatitis C virus release/assembly through perturbation of lipid metabolism
2017 StandoutNobel
Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial
2014 Standout
Molecular mechanisms of lipotoxicity and glucotoxicity in nonalcoholic fatty liver disease
2016
GRP78 expression inhibits insulin and ER stress–induced SREBP-1c activation and reduces hepatic steatosis in mice
2009
What We Talk About When We Talk About Fat
2014 Standout
Mechanisms for Insulin Resistance: Common Threads and Missing Links
2012 Standout
The unfolded protein response transducer IRE1α prevents ER stress‐induced hepatic steatosis
2011
Protective and pathogenic functions of macrophage subsets
2011 Standout
The UPR Activator ATF6 Responds to Proteotoxic and Lipotoxic Stress by Distinct Mechanisms
2018
Molecular analysis in two Tunisian families with combined factor V and factor VIII deficiency
2010
Endoplasmic reticulum-tethered transcription factor cAMP responsive element-binding protein, hepatocyte specific, regulates hepatic lipogenesis, fatty acid oxidation, and lipolysis upon metabolic stress in mice
2011
Energy Metabolism in the Liver
2014 Standout
Development of therapeutic antibodies for the treatment of diseases
2020 Standout
ER Stress-Inducible Factor CHOP Affects the Expression of Hepcidin by Modulating C/EBPalpha Activity
2009
Bispecific antibodies: a mechanistic review of the pipeline
2019
The role of ER stress in lipid metabolism and lipotoxicity
2016
Animal Models in the Study of the Unfolded Protein Response
2011
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Fine-Tuning of the Unfolded Protein Response: Assembling the IRE1α Interactome
2009
Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression
2019 StandoutNobel
NF-κB, inflammation, immunity and cancer: coming of age
2018 Standout
Inflammation in obesity, diabetes, and related disorders
2022 Standout
The unfolded protein response is required to maintain the integrity of the endoplasmic reticulum, prevent oxidative stress and preserve differentiation in β ‐cells
2010
Immunogenic cell death and DAMPs in cancer therapy
2012 Standout
Endoplasmic Reticulum Stress and Oxidative Stress in Cell Fate Decision and Human Disease
2014
A Fibrosis‐Independent Hepatic Transcriptomic Signature Identifies Drivers of Disease Progression in Primary Sclerosing Cholangitis
2020 StandoutNobel
Mice deficient in LMAN1 exhibit FV and FVIII deficiencies and liver accumulation of α1-antitrypsin
2011 StandoutNobel
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Molecular basis of LMAN1 in coordinating LMAN1-MCFD2 cargo receptor formation and ER-to-Golgi transport of FV/FVIII
2010
A Role of the Bile Salt Receptor FXR in Atherosclerosis
2010
EF-hand domains of MCFD2 mediate interactions with both LMAN1 and coagulation factor V or VIII
2009
Luminal Domain of ATF6 Alone Is Sufficient for Sensing Endoplasmic Reticulum Stress and Subsequent Transport to the Golgi Apparatus
2010
Regulation of basal cellular physiology by the homeostatic unfolded protein response
2010
Graft-versus-leukemia reactions after bone marrow transplantation
1990 Standout
Pharmacological ER stress promotes hepatic lipogenesis and lipid droplet formation.
2012
Induction of Liver Steatosis and Lipid Droplet Formation in ATF6α-Knockout Mice Burdened with Pharmacological Endoplasmic Reticulum Stress
2010
The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
2011 StandoutScience
Lipotoxicity and the gut-liver axis in NASH pathogenesis
2017
Inflammatory Bowel Disease
2010 Standout
The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis
2018 Standout
The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition
2014 Standout
Modular repeat protein sculpting using rigid helical junctions
2020 StandoutNobel
Interleukin-10 and the Interleukin-10 Receptor
2001 Standout
Inflammatory Mechanisms in Obesity
2011 Standout
Immune Interventions in Disease
1987
Structural basis for the cooperative interplay between the two causative gene products of combined factor V and factor VIII deficiency
2010
Human Fatty Liver Disease: Old Questions and New Insights
2011 StandoutScience
Targeted deletion of thioesterase superfamily member 1 promotes energy expenditure and protects against obesity and insulin resistance
2012
The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress
2011
A Homeostatic Shift Facilitates Endoplasmic Reticulum Proteostasis through Transcriptional Integration of Proteostatic Stress Response Pathways
2016
Inhibition of the oxygen sensor PHD2 in the liver improves survival in lactic acidosis by activating the Cori cycle
2015 StandoutNobel
Grp78 Heterozygosity Promotes Adaptive Unfolded Protein Response and Attenuates Diet-Induced Obesity and Insulin Resistance
2009
Nuclear factor‐erythroid 2‐related factor 1 regulates expression of proteasome genes in hepatocytes and protects against endoplasmic reticulum stress and steatosis in mice
2013
Works of Michael U. Callaghan being referenced
Emicizumab Prophylaxis in Hemophilia A with Inhibitors
2017
UPR Pathways Combine to Prevent Hepatic Steatosis Caused by ER Stress-Mediated Suppression of Transcriptional Master Regulators
2008
Prevalence and indicators of HIV and AIDS among adults admitted to medical and surgical wards in Blantyre, Malawi
2004
IL-2 enhances polyclonal IgM but not IgM-rheumatoid factor synthesis by activated human peripheral blood B cells
1993
Genotype-phenotype correlation in combined deficiency of factor V and factor VIII
2008
Alpha(human leukocyte)-interferon as treatment for non-small cell carcinoma of the lung: a phase II trial.
1983
Emicizumab Prophylaxis in Patients Who Have Hemophilia A without Inhibitors
2018