Citation Impact
Citing Papers
Antibody Format and Drug Release Rate Determine the Therapeutic Activity of Noninternalizing Antibody–Drug Conjugates
2015
Engineered anti-CD70 antibody-drug conjugate with increased therapeutic index
2008
The biomass distribution on Earth
2018 Standout
Intracellular Activation of SGN-35, a Potent Anti-CD30 Antibody-Drug Conjugate
2010
SLC46A3 Is Required to Transport Catabolites of Noncleavable Antibody Maytansine Conjugates from the Lysosome to the Cytoplasm
2015
Hydrazino-Pictet-Spengler Ligation as a Biocompatible Method for the Generation of Stable Protein Conjugates
2013
Formylglycine-generating enzyme binds substrate directly at a mononuclear Cu(I) center to initiate O 2 activation
2019 StandoutNobel
Results of a Pivotal Phase II Study of Brentuximab Vedotin for Patients With Relapsed or Refractory Hodgkin's Lymphoma
2012 Standout
LGR5-Targeted Antibody–Drug Conjugate Eradicates Gastrointestinal Tumors and Prevents Recurrence
2016
RN927C, a Site-Specific Trop-2 Antibody–Drug Conjugate (ADC) with Enhanced Stability, Is Highly Efficacious in Preclinical Solid Tumor Models
2016
Anetumab Ravtansine: A Novel Mesothelin-Targeting Antibody–Drug Conjugate Cures Tumors with Heterogeneous Target Expression Favored by Bystander Effect
2014
The Prioritization of Cancer Antigens: A National Cancer Institute Pilot Project for the Acceleration of Translational Research
2009 StandoutNobel
Comparative Binding of Disulfide-Bridged PEG-Fabs
2012
Bone grafts and biomaterials substitutes for bone defect repair: A review
2017 Standout
Methods to Make Homogenous Antibody Drug Conjugates
2014
Aldehyde Tag Coupled with HIPS Chemistry Enables the Production of ADCs Conjugated Site-Specifically to Different Antibody Regions with Distinct in Vivo Efficacy and PK Outcomes
2014
Genetically Encoded Azide Containing Amino Acid in Mammalian Cells Enables Site-Specific Antibody–Drug Conjugates Using Click Cycloaddition Chemistry
2015
Reconstitution of Formylglycine-generating Enzyme with Copper(II) for Aldehyde Tag Conversion
2015
Targeted glycan degradation potentiates the anticancer immune response in vivo
2020 StandoutNobel
A Polymer-Based Antibody–Vinca Drug Conjugate Platform: Characterization and Preclinical Efficacy
2015
Design, Synthesis, and Evaluation of Linker-Duocarmycin Payloads: Toward Selection of HER2-Targeting Antibody–Drug Conjugate SYD985
2015
DS-8201a, A Novel HER2-Targeting ADC with a Novel DNA Topoisomerase I Inhibitor, Demonstrates a Promising Antitumor Efficacy with Differentiation from T-DM1
2016
Sortase Enzyme-Mediated Generation of Site-Specifically Conjugated Antibody Drug Conjugates with High In Vitro and In Vivo Potency
2015
Engineering precision nanoparticles for drug delivery
2020 Standout
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
Pressure effects on in vivo microbial processes
2002
Key factors influencing ADME properties of therapeutic proteins: A need for ADME characterization in drug discovery and development
2015
Antibody-drug conjugates for cancer therapy: The technological and regulatory challenges of developing drug-biologic hybrids
2015
A view on drug resistance in cancer
2019 StandoutNature
Brentuximab Vedotin (SGN-35) for Relapsed CD30-Positive Lymphomas
2010
Modifying enzyme activity and selectivity by immobilization
2012 Standout
Enzyme immobilisation in biocatalysis: why, what and how
2013 Standout
Spatiotemporal delivery of bone morphogenetic protein enhances functional repair of segmental bone defects
2011
Reducing hydrophobicity of homogeneous antibody-drug conjugates improves pharmacokinetics and therapeutic index
2015
Cancer nanomedicine: progress, challenges and opportunities
2016 Standout
Clinical Trials of Cancer Therapies Targeting Prostate-Specific Membrane Antigen
2007
Analysis of antibody-drug conjugates by comprehensive on-line two-dimensional hydrophobic interaction chromatography x reversed phase liquid chromatography hyphenated to high resolution mass spectrometry. I − Optimization of separation conditions
2016
Site‐Specific and Stoichiometric Modification of Antibodies by Bacterial Transglutaminase
2010
Antibody-targeted drugs and drug resistance—Challenges and solutions
2014
Prodrug Strategies in Anticancer Chemotherapy
2007
The challenge of establishing preclinical models for segmental bone defect research
2009
Linker Technologies for Antibody–Drug Conjugates
2013
Cutting-edge mass spectrometry methods for the multi-level structural characterization of antibody-drug conjugates
2015
Cancer Statistics, 2006
2006 Standout
Nanoparticle therapeutics: an emerging treatment modality for cancer
2008 Standout
Rapid identification of reactive cysteine residues for site-specific labeling of antibody-Fabs
2008
Characterization of Cysteine-Linked Conjugation Profiles of Immunoglobulin G1 and Immunoglobulin G2 Antibody–Drug Conjugates
2015
Organometallic palladium reagents for cysteine bioconjugation
2015 Nature
Treatment parameters modulating regression of human melanoma xenografts by an antibody–drug conjugate (CR011-vcMMAE) targeting GPNMB
2007
CRISPR-Cas9 screens identify regulators of antibody–drug conjugate toxicity
2019 StandoutNobel
Self-hydrolyzing maleimides improve the stability and pharmacological properties of antibody-drug conjugates
2014
M13-templated magnetic nanoparticles for targeted in vivo imaging of prostate cancer
2012
Effects of extracellular matrix viscoelasticity on cellular behaviour
2020 StandoutNature
Cancer stem cells revisited
2017 Standout
Antibody targeted drugs as cancer therapeutics
2006
The Heat Shock Response: Life on the Verge of Death
2010 Standout
The discovery and development of brentuximab vedotin for use in relapsed Hodgkin lymphoma and systemic anaplastic large cell lymphoma
2012
LYTACs that engage the asialoglycoprotein receptor for targeted protein degradation
2021 StandoutNobel
Potent antibody drug conjugates for cancer therapy
2009
The biotechnological potential of piezophiles
2001
Antibody therapy of cancer
2012 Standout
Site-specific antibody drug conjugates for cancer therapy
2013
Combination of the anti‐CD30‐auristatin‐E antibody‐drug conjugate (SGN‐35) with chemotherapy improves antitumour activity in Hodgkin lymphoma
2008
Antibody–drug conjugates: targeted drug delivery for cancer
2010
Practical method development for the separation of monoclonal antibodies and antibody-drug-conjugate species in hydrophobic interaction chromatoraphy, part 2: Optimization of the phase system
2016
Fucose-specific conjugation of hydrazide derivatives to a vascular-targeting monoclonal antibody in IgG format
2012
Targeted therapy for Hodgkin lymphoma and systemic anaplastic large cell lymphoma: focus on brentuximab vedotin
2013
Practical method development for the separation of monoclonal antibodies and antibody-drug-conjugate species in hydrophobic interaction chromatography, part 1: optimization of the mobile phase
2015
Antibody–drug conjugates: current status and future directions
2013
Effects of antibody, drug and linker on the preclinical and clinical toxicities of antibody-drug conjugates
2016
8thAnnual European Antibody Congress 2012
2013
Lysosomal Trafficking and Cysteine Protease Metabolism Confer Target-specific Cytotoxicity by Peptide-linked Anti-CD30-Auristatin Conjugates
2006
Site-specific modification of ED-B-targeting antibody using intein-fusion technology
2011
Matching chelators to radiometals for radiopharmaceuticals
2013 Standout
Interactions with Aromatic Rings in Chemical and Biological Recognition
2003 Standout
Strategies and challenges for the next generation of antibody–drug conjugates
2017 Standout
A sensitive multidimensional method for the detection, characterization, and quantification of trace free drug species in antibody-drug conjugate samples using mass spectral detection
2015
Site-specific chemical protein conjugation using genetically encoded aldehyde tags
2012 StandoutNobel
Targeted drug delivery for cancer therapy: the other side of antibodies
2012
Emerging formats for next-generation antibody drug conjugates
2015
A Bioorthogonal Reaction of N‐Oxide and Boron Reagents
2015 StandoutNobel
Paul Ehrlich's magic bullet concept: 100 years of progress
2008 Standout
Antibody–cytotoxic agent conjugates for cancer therapy
2005
π-Clamp-mediated cysteine conjugation
2015
Programmable design of orthogonal protein heterodimers
2018 StandoutNatureNobel
SNAP-Tag Technology Mediates Site Specific Conjugation of Antibody Fragments with a Photosensitizer and Improves Target Specific Phototoxicity in Tumor Cells
2011
Functional Expression and Characterization of an Archaeal Aquaporin
2003 StandoutNobel
Antibody-drug conjugates
2013
Engineered Nanoparticles for Drug Delivery in Cancer Therapy
2014 Standout
Antibody–Drug Conjugates: An Emerging Concept in Cancer Therapy
2014
Arming antibodies: prospects and challenges for immunoconjugates
2005
Cancer Therapy with Radiolabeled and Drug/Toxin-conjugated Antibodies
2005
Antibody–Drug Conjugates for Tumor Targeting—Novel Conjugation Chemistries and the Promise of non-IgG Binding Proteins
2015
Computational design of a synthetic PD-1 agonist
2021 StandoutNobel
Characterization of Therapeutic Antibodies and Related Products
2012
Current management of long bone large segmental defects
2010
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Design and Application of Antibody Cysteine Variants
2010
Microbial Provinces in the Subseafloor
2009
Supramolecular Polymerization
2009 Standout
Noncovalent Functionalization of Graphene and Graphene Oxide for Energy Materials, Biosensing, Catalytic, and Biomedical Applications
2016 Standout
Dynamic Metabolic Adjustments and Genome Plasticity Are Implicated in the Heat Shock Response of the Extremely Thermoacidophilic ArchaeonSulfolobus solfataricus
2006
Water as an Active Constituent in Cell Biology
2007 Standout
New Approaches in the Treatment of Critical‐Size Segmental Defects in Long Bones
2007
Molecular Basis of Bacterial Outer Membrane Permeability Revisited
2003 Standout
Methods for site-specific drug conjugation to antibodies
2013
Trop-2 is a novel target for solid cancer therapy with sacituzumab govitecan (IMMU-132), an antibody-drug conjugate (ADC)*
2015
Impact of Drug Conjugation on Pharmacokinetics and Tissue Distribution of Anti-STEAP1 Antibody–Drug Conjugates in Rats
2011
Metabolic Engineering of Monoclonal Antibody Carbohydrates for Antibody–Drug Conjugation
2013
RP-HPLC DAR Characterization of Site-Specific Antibody Drug Conjugates Produced in a Cell-Free Expression System
2016
Hierarchically porous materials: synthesis strategies and structure design
2016 Standout
New Strategies for Fluorescent Probe Design in Medical Diagnostic Imaging
2009 Standout
Site-Specific Dual Antibody Conjugation via Engineered Cysteine and Selenocysteine Residues
2015
Site-Specific Antibody–Drug Conjugation through Glycoengineering
2014
Biocompatible SuFEx Click Chemistry: Thionyl Tetrafluoride (SOF4)‐Derived Connective Hubs for Bioconjugation to DNA and Proteins
2019 StandoutNobel
Antibody Conjugates: From Heterogeneous Populations to Defined Reagents
2015
Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag
2009 StandoutNobel
Polymers for 3D Printing and Customized Additive Manufacturing
2017 Standout
Targeted delivery of methotrexate to epidermal growth factor receptor–positive brain tumors by means of cetuximab (IMC-C225) dendrimer bioconjugates
2006
Antibody–drug conjugates (ADCs) for cancer therapy: Strategies, challenges, and successes
2018
Why molecules move along a temperature gradient
2006 Standout
Bridging Disulfides for Stable and Defined Antibody Drug Conjugates
2014
Rational Tuning of Fluorobenzene Probes for Cysteine‐Selective Protein Modification
2018 StandoutNobel
A View of the Hydrophobic Effect
2001
Potent Antitumor Activity of an Auristatin-Conjugated, Fully Human Monoclonal Antibody to Prostate-Specific Membrane Antigen
2006
Targeted Anticancer Immunotoxins and Cytotoxic Agents with Direct Killing Moieties
2006
Computation-Guided Rational Design of a Peptide Motif That Reacts with Cyanobenzothiazoles via Internal Cysteine–Lysine Relay
2018 StandoutNobel
Carbon Nanomaterials for Biological Imaging and Nanomedicinal Therapy
2015 Standout
Glycans of Antibodies as a Specific Site for Drug Conjugation Using Glycosyltransferases
2015
Precision glycocalyx editing as a strategy for cancer immunotherapy
2016 StandoutNobel
Characterization of therapeutic antibodies and related products by two-dimensional liquid chromatography coupled with UV absorbance and mass spectrometric detection
2016
Impact of Natural Products on Developing New Anti-Cancer Agents
2009 Standout
Site-Specific Conjugation of Monomethyl Auristatin E to Anti-CD30 Antibodies Improves Their Pharmacokinetics and Therapeutic Index in Rodent Models
2015
Site-Specific Antibody–Drug Conjugates: The Nexus of Bioorthogonal Chemistry, Protein Engineering, and Drug Development
2014 StandoutNobel
Targeting LGR5 + cells with an antibody-drug conjugate for the treatment of colon cancer
2015
Stabilization of multimeric enzymes: Strategies to prevent subunit dissociation
2009
Site-specifically 89Zr-labeled monoclonal antibodies for ImmunoPET
2010
Sensitive ELISA Method for the Measurement of Catabolites of Antibody–Drug Conjugates (ADCs) in Target Cancer Cells
2015
Tandem Native Mass-Spectrometry on Antibody–Drug Conjugates and Submillion Da Antibody–Antigen Protein Assemblies on an Orbitrap EMR Equipped with a High-Mass Quadrupole Mass Selector
2015
pH-Operated Nanopistons on the Surfaces of Mesoporous Silica Nanoparticles
2010 StandoutNobel
Brentuximab Vedotin (SGN-35)
2011
Mild Method for Succinimide Hydrolysis on ADCs: Impact on ADC Potency, Stability, Exposure, and Efficacy
2014
Antibody-drug conjugate model fast characterization by LC-MS following IdeS proteolytic digestion
2013
Osmoadaptation and osmoregulation in archaea
2000
Dendrimers Designed for Functions: From Physical, Photophysical, and Supramolecular Properties to Applications in Sensing, Catalysis, Molecular Electronics, Photonics, and Nanomedicine
2010 Standout
A Versatile Bifunctional Chelate for Radiolabeling Humanized Anti-CEA Antibody with In-111 and Cu-64 at Either Thiol or Amino Groups: PET Imaging Of CEA-Positive Tumors with Whole Antibodies
2007
Linkers Having a Crucial Role in Antibody–Drug Conjugates
2016
Mass Spectrometric Characterization of Transglutaminase Based Site-Specific Antibody–Drug Conjugates
2013
Transglutaminase-Based Chemo-Enzymatic Conjugation Approach Yields Homogeneous Antibody–Drug Conjugates
2014
One-Step Conjugation Method for Site-Specific Antibody–Drug Conjugates through Reactive Cysteine-Engineered Antibodies
2016
Contribution of Linker Stability to the Activities of Anticancer Immunoconjugates
2008
Improving the Serum Stability of Site-Specific Antibody Conjugates with Sulfone Linkers
2014
PK Assays for Antibody–Drug Conjugates: Case Study with Ado-Trastuzumab Emtansine
2013
Works of Michael Sun being referenced
[27] Pressure effects on activity and stability of hyperthermophilic enzymes
2001
The efficacy of cylindrical titanium mesh cage for the reconstruction of a critical-size canine segmental femoral diaphyseal defect
2006
Fourth World Antibody-Drug Conjugate Summit
2012
Pressure‐induced thermostabilization of glutamate dehydrogenase from the hyperthermophile pyrococcus furiosus
1999
Effects of Drug Loading on the Antitumor Activity of a Monoclonal Antibody Drug Conjugate
2004
SGN-35, an Anti-CD30 Antibody-Drug Conjugate, Exhibits Potent Antitumor Activity for the Treatment of CD30+ Malignancies.
2005
Reduction−Alkylation Strategies for the Modification of Specific Monoclonal Antibody Disulfides
2005
In vivoDrug-Linker Stability of an Anti-CD30 Dipeptide-Linked Auristatin Immunoconjugate
2005